G Jeffery

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Architecture of the optic chiasm and the mechanisms that sculpt its development
    G Jeffery
    University College London, Institute of Ophthalmology, London, United Kingdom
    Physiol Rev 81:1393-414. 2001
  2. ncbi request reprint Cellular localisation of metabotropic glutamate receptors in the mammalian optic nerve: a mechanism for axon-glia communication
    G Jeffery
    Institute of Ophthalmology, University College London, UK
    Brain Res 741:75-81. 1996
  3. ncbi request reprint Correction of retinal abnormalities found in albinism by introduction of a functional tyrosinase gene in transgenic mice and rabbits
    G Jeffery
    Institute of Ophthalmology, University College London, UK
    Brain Res Dev Brain Res 99:95-102. 1997
  4. ncbi request reprint First evidence of diversity in eutherian chiasmatic architecture: tree shrews, like marsupials, have spatially segregated crossed and uncrossed chiasmatic pathways
    G Jeffery
    Institute of Ophthalmology, University College London, United Kingdom
    J Comp Neurol 390:183-93. 1998
  5. ncbi request reprint PNS features of rodent optic nerve axons
    G Jeffery
    Institute of Ophthalmology, University College London, United Kingdom
    J Comp Neurol 366:370-8. 1996
  6. ncbi request reprint Correction of abnormal retinal pathways found with albinism by introduction of a functional tyrosinase gene in transgenic mice
    G Jeffery
    Institute of Ophthalmology, London University, United Kingdom
    Dev Biol 166:460-4. 1994
  7. ncbi request reprint Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium
    M Cayouette
    Medical Research Council Laboratory for Molecular Cell Biology and the Biology Department, University College London, London WC1E 6BT, United Kingdom
    J Neurosci 21:5643-51. 2001
  8. ncbi request reprint Oxygen modulates cell death in the proliferating retina
    M Semo
    University College London, Institute of Ophthalmology, London EC1V 9EL, UK
    Eur J Neurosci 13:1257-60. 2001
  9. ncbi request reprint Growth dynamics of the developing lateral geniculate nucleus
    A L Williams
    Institute of Ophthalmology, University College London, London EC1V 9EL, United Kingdom
    J Comp Neurol 430:332-42. 2001
  10. pmc Segregated hemispheric pathways through the optic chiasm distinguish primates from rodents
    G Jeffery
    Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK
    Neuroscience 157:637-43. 2008

Detail Information

Publications13

  1. ncbi request reprint Architecture of the optic chiasm and the mechanisms that sculpt its development
    G Jeffery
    University College London, Institute of Ophthalmology, London, United Kingdom
    Physiol Rev 81:1393-414. 2001
    ..Furthermore, in albinos, where many cells do not exit the cell cycle at normal times, there are systematic chiasmatic abnormalities in ganglion cell projections...
  2. ncbi request reprint Cellular localisation of metabotropic glutamate receptors in the mammalian optic nerve: a mechanism for axon-glia communication
    G Jeffery
    Institute of Ophthalmology, University College London, UK
    Brain Res 741:75-81. 1996
    ..It is probable that in the adult this form of signalling underpins a range of functions that have yet to be described...
  3. ncbi request reprint Correction of retinal abnormalities found in albinism by introduction of a functional tyrosinase gene in transgenic mice and rabbits
    G Jeffery
    Institute of Ophthalmology, University College London, UK
    Brain Res Dev Brain Res 99:95-102. 1997
    ..Hence, the tyrosinase gene is responsible for each of the retinal deficits associated with albinism. However, it is not clear whether this is due to the absence of melanin or whether the key agent is an associated cell product...
  4. ncbi request reprint First evidence of diversity in eutherian chiasmatic architecture: tree shrews, like marsupials, have spatially segregated crossed and uncrossed chiasmatic pathways
    G Jeffery
    Institute of Ophthalmology, University College London, United Kingdom
    J Comp Neurol 390:183-93. 1998
    ....
  5. ncbi request reprint PNS features of rodent optic nerve axons
    G Jeffery
    Institute of Ophthalmology, University College London, United Kingdom
    J Comp Neurol 366:370-8. 1996
    ..They develop caudally, mirroring glial maturation. It is probable that the glia are maturing astrocytes that provide a scaffold for this feature of optic axon trajectory...
  6. ncbi request reprint Correction of abnormal retinal pathways found with albinism by introduction of a functional tyrosinase gene in transgenic mice
    G Jeffery
    Institute of Ophthalmology, London University, United Kingdom
    Dev Biol 166:460-4. 1994
    ..The establishment of the transgenic model provides a unique tool with which to investigate the way in which melanin shapes this region of the developing mammalian visual system...
  7. ncbi request reprint Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium
    M Cayouette
    Medical Research Council Laboratory for Molecular Cell Biology and the Biology Department, University College London, London WC1E 6BT, United Kingdom
    J Neurosci 21:5643-51. 2001
    ....
  8. ncbi request reprint Oxygen modulates cell death in the proliferating retina
    M Semo
    University College London, Institute of Ophthalmology, London EC1V 9EL, UK
    Eur J Neurosci 13:1257-60. 2001
    ..These results highlight the important role played by oxygen during early natural cell death in the retina and reveal the different developmental conditions present in the retinae of the two pigmentation phenotypes examined...
  9. ncbi request reprint Growth dynamics of the developing lateral geniculate nucleus
    A L Williams
    Institute of Ophthalmology, University College London, London EC1V 9EL, United Kingdom
    J Comp Neurol 430:332-42. 2001
    ..After segregation, nuclear growth is mainly isotropic. The mature shape of the nucleus is achieved before it reaches its full size and while cell density and cell sizes are still changing...
  10. pmc Segregated hemispheric pathways through the optic chiasm distinguish primates from rodents
    G Jeffery
    Institute of Ophthalmology, University College London, Bath Street, London EC1V 9EL, UK
    Neuroscience 157:637-43. 2008
    ..Our results therefore suggest that both the organization and development of the primate optic chiasm differ markedly from that revealed in rodents and carnivores...
  11. ncbi request reprint The retinal pigment epithelium as a developmental regulator of the neural retina
    G Jeffery
    Institute of Ophthalmology, UCL, London, UK
    Eye (Lond) 12:499-503. 1998
    ..This may be caused by a reduction in ocular DOPA in albinos as this is in the synthetic pathway of melanin and is a known cell cycle regulator...
  12. ncbi request reprint Distribution of metabotropic glutamate receptors in the superior colliculus of the adult rat, ferret and cat
    J Cirone
    Department of Visual Science, Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Neuroscience 109:779-86. 2002
    ..This is particularly so for the Group II and Group III receptors, which appear to have specific and distinct roles in the modulation of visual responses...
  13. ncbi request reprint Chiasm formation in man is fundamentally different from that in the mouse
    M M Neveu
    Institute of Ophthalmology, University College London, London, UK
    Eye (Lond) 21:1264-70. 2007
    ..This implies that optic chiasm formation in rodents and ferrets is not common to placental mammals in general...