Sam M Janes
Affiliation: University College London
Navani N, Nankivell M, Lawrence D, Lock S, Makker H, Baldwin D, et al
. Lung cancer diagnosis and staging with endobronchial ultrasound-guided transbronchial needle aspiration compared with conventional approaches: an open-label, pragmatic, randomised controlled trial. Lancet Respir Med. 2015;3:282-9 pubmed publisher
..UK Medical Research Council. ..
Lourenço S, Teixeira V, Kalber T, José R, Floto R, Janes S. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol. 2015;194:3463-74 pubmed publisher
..This improved understanding of MSC tumor tropism will further enable development of novel cellular therapies for cancers. ..
Crowley C, Klanrit P, Butler C, Varanou A, PlatÃ© M, Hynds R, et al
. Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold. Biomaterials. 2016;83:283-93 pubmed publisher
Yuan Z, Lourenco S, Sage E, Kolluri K, Lowdell M, Janes S. Cryopreservation of human mesenchymal stromal cells expressing TRAIL for human anti-cancer therapy. Cytotherapy. 2016;18:860-9 pubmed publisher
..This study shows that cryopreservation is unlikely to affect the therapeutic properties of MSCTRAIL and supports the generation of a cryopreserved master cell bank. ..
Butler C, Hynds R, Crowley C, Gowers K, Partington L, Hamilton N, et al
. Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials. 2017;124:95-105 pubmed publisher
..3-8 weeks) does not compromise the quality of human tracheal scaffold generated. These findings might inform clinical decellularization techniques as VAD offers accelerated scaffold production and reduces the associated costs. ..
Thakrar R, Pennycuick A, Borg E, Janes S. Preinvasive disease of the airway. Cancer Treat Rev. 2017;58:77-90 pubmed publisher
..In this paper we describe the known biology and natural history of preinvasive lesions and review the current treatment strategies. ..
Hynds R, Janes S. Airway Basal Cell Heterogeneity and Lung Squamous Cell Carcinoma. Cancer Prev Res (Phila). 2017;10:491-493 pubmed publisher
..i>Cancer Prev Res; 10(9); 491-3. Â©2017 AACRSee related article by Pagano et al., p. 514. ..
Sage E, Thakrar R, Janes S. Genetically modified mesenchymal stromal cells in cancer therapy. Cytotherapy. 2016;18:1435-1445 pubmed publisher
Taylor S, Mallett S, Miles A, Beare S, Bhatnagar G, Bridgewater J, et al
. Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L). BMC Cancer. 2017;17:299 pubmed publisher
..Streamline C ISRCTN43958015 (registered 25/7/2012). Streamline L ISRCTN50436483 (registered 31/7/2012). ..