Research Topics
| William H JamesSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
The relevance of the epidemiology of human sex ratios at birth to some medical problemsWilliam H James
Department of Genetics, Evolution and Environment, University College London, London, UK
Paediatr Perinat Epidemiol 26:181-9. 2012....
Hypotheses on the stability and variation of human sex ratios at birthWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
J Theor Biol 310:183-6. 2012..3. It has been proposed by Catalano that other variation in sex ratios at birth is associated with maternal stress during pregnancy. He and his co-workers have adduced substantial quantities of data to support this hypothesis too...
A potential explanation of some established major risk factors for autismWilliam H James
Department of Genetics, Evolution and Environment, University College, London, UK
Dev Med Child Neurol 54:301-5. 2012..If that were correct, it would follow that high maternally derived intrauterine androgen concentrations may be a major environmental cause of autism...
Are there preconceptional determinants of mammalian sex? A response to Boklage (2005)William H James
The Galton Laboratory, University College London, London, UK
Hum Reprod 21:2486-90. 2006..Efforts should be made to confirm or discredit these suspicions...
Monitoring reproductive health in Europe: what are the best indicators?William H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
Hum Reprod 22:1197-9. 2007..Efforts should be made to assess the sperm quality of volunteer donors in each European country...
The validity of Weinberg's Differential RuleWilliam H James
The Galton Laboratory, University College London, London, United Kingdom
Twin Res Hum Genet 10:771-2. 2007..This is in spite of the fact that one of the premises he used in its derivation is almost certainly, to some extent, false. An explanation is offered here...
Further evidence that some male-based neurodevelopmental disorders are associated with high intrauterine testosterone concentrationsWilliam H James
The Galton Laboratory, University College London, Wolfson House, London, UK
Dev Med Child Neurol 50:15-8. 2008..Provisionally, the data may be interpreted as suggesting that RD may be caused by high intrauterine testosterone levels, and confirming the hypothesis that ADHD is partially caused by high intrauterine testosterone...
Do celebrities' cosmetic breast augmentations jeopardise their fans' willingness to breast feed?William H James
Galton Laboratory, University College London, 4 Stephenson Way, London, NW1 2HE, UK
Paediatr Perinat Epidemiol 22:116. 2008
Sex ratios in twin families: commentary on Fellman and ErikssonWilliam H James
The Galton Laboratory, University College London, London, United Kingdom
Twin Res Hum Genet 11:215-8. 2008..Lastly, appeals are made for (a) data that would test the reliability of the data of Geissler and Lommatsch on the point questioned above, and (b) data on the sex ratios of offspring of twins by the sex and zygosity of the twin parents...
Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conceptionWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
J Endocrinol 198:3-15. 2008..The purpose of this article is to elicit such comment. Readers are requested to read the accompanying editorial (Clark & Davis 2008) to gain a better perspective of this hypothesis article...
Potential solutions to problems posed by the offspring sex ratios of people with parasitic and viral infectionsWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
Folia Parasitol (Praha) 57:114-20. 2010..And if this solution turns out to be correct, it would suggest new endocrine means of combating hepatitis B infection...
The variations of human sex ratio at birth with time of conception within the cycle, coital rate around the time of conception, duration of time taken to achieve conception, and duration of gestation: a synthesisWilliam H James
Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
J Theor Biol 255:199-204. 2008..Lastly, sex ratio varies substantially with DOG, though the explanation for this is not established: it is suggested that the present treatment provides a testable framework for such an explanation...
The variations of human sex ratio at birth during and after wars, and their potential explanationsWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
J Theor Biol 257:116-23. 2009..However, I have been unable to locate direct supporting sex ratio data relating to any conflict before World War One. So it would be useful if historical demographers were to search for such data relating to these earlier wars...
The variances of the distributions of the combinations of the sexes within mammalian litters: notes to mark the centenary of the problemWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
J Theor Biol 259:264-8. 2009..And it is a standard result in probability theory that such variation causes sub-binomial variance...
The sex ratios of monozygotic and dizygotic twinsWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
Twin Res Hum Genet 13:381-2. 2010..Fellman and Eriksson (2010) cited my suggestion that the sex ratio (proportion male) of monozygotic (MZ) twins is lower than that of dizygotic (DZ) twins (James 1975). Here I offer elaborations on and potential explanations for this...
Possible constraints on adaptive variation in sex ratio at birth in humans and other primatesWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
J Theor Biol 238:383-94. 2006..It seems that gonadal hormones are responsible for adaptive variation; and that maternal adrenal hormones are responsible for maladaptive variation. In evolutionary terms, gonadal hormones precede adrenal hormones...
Further evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conceptionWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
Hum Reprod 19:1250-6. 2004..It is intended that a reader who has read both this paper and my previous paper should be aware of all the data relating to the hypothesis [James WH (1996), J Theor Biol 180, 271-286]...
Behavioural and biological determinants of human sex ratio at birthWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
J Biosoc Sci 42:587-99. 2010..It is noted that the lines of evidence for three hypotheses (James', Manning's and Baron-Cohen's) are mutually supportive...
Further support for the hypothesis that parental hormone levels around the time of conception are associated with human sex ratios at birthWilliam H James
The Galton Laboratory, University College London, UK
J Biosoc Sci 40:855-61. 2008..It is intended that anyone who has read the present note and my two previous papers (James, 1996, 2004) should be aware of all the data relating to the hypothesis...
Offspring sex ratios at birth as markers of paternal endocrine disruptionWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
Environ Res 100:77-85. 2006....
The sexual orientation of men who were brought up in gay or lesbian householdsWilliam H James
The Galton Laboratory, University College London
J Biosoc Sci 36:371-4. 2004..Here it is argued that the available data on men raised by same-sex parents cannot validly be interpreted as supporting or refuting this suggestion...
The categories of evidence relating to the hypothesis that mammalian sex ratios at birth are causally related to the hormone concentrations of both parents around the time of conceptionWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
J Biosoc Sci 43:167-84. 2011..This observational/correlational evidence is tabulated to illustrate its consistency...
Variation of the probability of a male birth within and between sibshipsWilliam H James
Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, England
Hum Biol 81:13-22. 2009..Contrary to their inference, a binomial distribution may result when equal and counterbalancing measures of Poisson and Lexis variation are simultaneously present. These conditions are approximately met with respect to human births...
Biological and psychosocial determinants of male and female human sexual orientationWilliam H James
The Galton Laboratory, University College London
J Biosoc Sci 37:555-67. 2005..Methods of testing some of these ideas are presented...
Amendments to hypotheses on the proximate causes of variation in human sex ratios at birth with parental infection with hepatitis B virus or Toxoplasma gondiiWilliam H James
The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
J Biosoc Sci 43:247-51. 2011..Subsequent research suggests that these hypotheses need amending. A detailed account of the amendments is given elsewhere in a specialized journal (James, 2010a). Here they are summarized...
'Over-ripeness ovopathy, sex ratio increase and sex ratio reversal a challenging hypothesis for sex ratio modulation': an alternative interpretationWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
Hum Reprod 19:775-7. 2004..Finally, it is suggested that there is a circularity in his presentation of his concept of sex ratio 'reversal'...
The cause(s) of the fraternal birth order effect in male homosexualityWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE
J Biosoc Sci 36:51-9, 61-2. 2004..Lastly, there seem likely to be causes common to male homosexuality and paedophilia. They may include sexual (or quasi-sexual) experience in childhood or adolescence...
Two hypotheses on the causes of male homosexuality and paedophiliaWilliam H James
The Galton Laboratory, University College London
J Biosoc Sci 38:745-61. 2006..To summarize: most boys who experience CSA do not later develop into homosexuals or paedophiles. However, the available evidence suggests that a few do so as a result of the abuse...
Variation of human sex ratios at birth by the sex combinations of the existing sibs, and by reproductive stopping rules: comments on Garenne (2009)William H James
The Galton Laboratory, University College London, UK
J Biosoc Sci 43:751-60, author reply 761-3. 2011..I suggest that they may reveal it - but do not cause it. Moreover, I suggest that the effects of such stopping rules may be counter-intuitive...
Potential of the hormonal hypothesis of sex ratio to explain the unusual sex ratios typical of some malformationsWilliam H James
The Galton Laboratory, University College London, Wolfson House, London, England
Teratology 66:101-2; author reply 103-4. 2002
Evidence that intrauterine and postnatal androgens affect the development of pyloric stenosisWilliam H James
Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
Birth Defects Res A Clin Mol Teratol 70:37-9. 2004..Electronic data retrieval systems do not access incidentally recorded data such as sib sex ratios). CONCLUSIONS: It is hypothesized that high intrauterine and early postnatal androgen levels constitute an environmental cause of PS...
Hypotheses on how selection for some traits in rodents led to correlated responses in offspring sex ratiosWilliam H James
The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2HE, UK
J Theor Biol 228:1-6. 2004..If this line of reasoning were correct, the selection for sex drive would be expected to be accompanied by correlated changes in offspring sex ratio...
Testosterone and male fertility in red deerWilliam H James
Science 316:980-1; author reply 980-1. 2007
Significance of sib sex ratios in testing the hypothesis that some sex-biased congenital malformations are caused by unusual maternal hormone profilesWilliam H James
Birth Defects Res A Clin Mol Teratol 67:274-5; author reply 273. 2003
Birthweight in dizygotic twinsWilliam H James
Twin Res 5:309; author reply 10. 2002
Fish eaters and sex ratioWilliam H James
J Occup Environ Med 44:885-6; author reply 887-8. 2002
Re: "Brothers and reduction of the birth weight of later-born siblings"William H James
Am J Epidemiol 168:665; author reply 665-6. 2008
Periconceptual parental smoking and sex ratio of offspringWilliam H James
Lancet 360:1515; author reply 1515-6. 2002
The curious negative (protective?) associations between Parkinson's disease and certain behavioral risk factorsWilliam H James
Neuroepidemiology 21:305-6. 2002
Is omphalocele a consequence of high maternal estrogen levels?William H James
Teratology 66:59; author reply 60. 2002
Do gonadal hormones confound between parental smoking and offspring sex ratio?William H James
Int J Epidemiol 33:226. 2004
Parental exposure to dioxin and offspring sex ratiosWilliam H James
Environ Health Perspect 110:A502; discussion A502. 2002
Evidence that non-ionizing radiation alters men's hormone levelsWilliam H James
J Occup Environ Med 44:305-7; author reply 307. 2002
Smoking, sperm quality and testosterone levelWilliam H James
Hum Reprod 17:3275-6. 2002
Sex ratio of offspring born to men exposed to polychlorinated biphenylsWilliam H James
Lancet 360:1887. 2002
Food preferences, testosterone concentrations and offspring sex ratios of female miceWilliam H James
Psychoneuroendocrinology 28:1044-5; author reply 1045-6. 2003
A further note on the sex ratios of births conceived during wartimeWilliam H James
Hum Reprod 19:1495; author reply 1495-6. 2004
The sex ratio of pregnancies complicated by hospitalisation for hyperemesis gravidarumWilliam H James
BJOG 111:636. 2004
A hypothesis on the sexual behaviour of men who are destined to develop prostate cancerWilliam H James
Int J Epidemiol 34:483-5. 2005
The sex ratio of offspring of male gasoline filling station workersWilliam H James
J Epidemiol Community Health 59:339. 2005
Response to the "pooling of heterogeneous data"William H James
Fertil Steril 80:680-1. 2003
Fetal sex and intrauterine growth restrictionWilliam H James
Am J Obstet Gynecol 195:1498; author reply 1498-9. 2006
Sex ratios of offspring of patients with breast cancer and other endocrine related cancersWilliam H James
Int J Cancer 119:2710-1; author reply 2712. 2006
Sex ratios of births conceived during wartimeWilliam H James
Hum Reprod 18:1133-4. 2003
Re: Fetal testosterone and sex differencesWilliam H James
Early Hum Dev 84:43. 2008
Support for a hypothesis on the offspring sex ratios of hepatitis B carriersWilliam H James
J Theor Biol 247:395. 2007
Gestation and birthweight in dizygotic twinsWilliam H James
Lancet 359:171-2. 2002
Re: Prostate cancer in fathers with fewer male offspring: the Jerusalem Perinatal Study cohortWilliam H James
J Natl Cancer Inst 99:902; author reply 903-4. 2007
The causes of the excess males among pre-term and post-term birthsWilliam H James
Hum Reprod 18:655-6. 2003
Hormone levels in pre-eclampsiaWilliam H James
Acta Obstet Gynecol Scand 81:1152; author reply 1152. 2002
Smoking and sex selection?--Not proven yetWilliam H James
Fertil Steril 80:1289; author reply 1290. 2003
