William H James

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi request reprint A potential explanation of some established major risk factors for autism
    William H James
    Department of Genetics, Evolution and Environment, University College, London, UK
    Dev Med Child Neurol 54:301-5. 2012
  2. doi request reprint Evolution and the variation of mammalian sex ratios at birth: reflections on Trivers and Willard (1973)
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    J Theor Biol 334:141-8. 2013
  3. doi request reprint The relevance of the epidemiology of human sex ratios at birth to some medical problems
    William H James
    Department of Genetics, Evolution and Environment, University College London, London, UK
    Paediatr Perinat Epidemiol 26:181-9. 2012
  4. doi request reprint Hypotheses on the stability and variation of human sex ratios at birth
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
    J Theor Biol 310:183-6. 2012
  5. doi request reprint The variations of human sex ratio at birth during and after wars, and their potential explanations
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    J Theor Biol 257:116-23. 2009
  6. doi request reprint Further evidence that some male-based neurodevelopmental disorders are associated with high intrauterine testosterone concentrations
    William H James
    The Galton Laboratory, University College London, Wolfson House, London, UK
    Dev Med Child Neurol 50:15-8. 2008
  7. ncbi request reprint The validity of Weinberg's Differential Rule
    William H James
    The Galton Laboratory, University College London, London, United Kingdom
    Twin Res Hum Genet 10:771-2. 2007
  8. ncbi request reprint Are there preconceptional determinants of mammalian sex? A response to Boklage (2005)
    William H James
    The Galton Laboratory, University College London, London, UK
    Hum Reprod 21:2486-90. 2006
  9. doi request reprint Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    J Endocrinol 198:3-15. 2008
  10. doi request reprint Sex ratios in twin families: commentary on Fellman and Eriksson
    William H James
    The Galton Laboratory, University College London, London, United Kingdom
    Twin Res Hum Genet 11:215-8. 2008

Detail Information

Publications63

  1. doi request reprint A potential explanation of some established major risk factors for autism
    William H James
    Department of Genetics, Evolution and Environment, University College, London, UK
    Dev Med Child Neurol 54:301-5. 2012
    ..If that were correct, it would follow that high maternally derived intrauterine androgen concentrations may be a major environmental cause of autism...
  2. doi request reprint Evolution and the variation of mammalian sex ratios at birth: reflections on Trivers and Willard (1973)
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    J Theor Biol 334:141-8. 2013
    ..TW reasoning applies to both parents, not just the mother. Indeed, the TW prediction seems fulfilled more generally by fathers than by mothers. My hormonal hypothesis can apparently explain both the successes and the failures of TW. ..
  3. doi request reprint The relevance of the epidemiology of human sex ratios at birth to some medical problems
    William H James
    Department of Genetics, Evolution and Environment, University College London, London, UK
    Paediatr Perinat Epidemiol 26:181-9. 2012
    ....
  4. doi request reprint Hypotheses on the stability and variation of human sex ratios at birth
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
    J Theor Biol 310:183-6. 2012
    ..3. It has been proposed by Catalano that other variation in sex ratios at birth is associated with maternal stress during pregnancy. He and his co-workers have adduced substantial quantities of data to support this hypothesis too...
  5. doi request reprint The variations of human sex ratio at birth during and after wars, and their potential explanations
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    J Theor Biol 257:116-23. 2009
    ..However, I have been unable to locate direct supporting sex ratio data relating to any conflict before World War One. So it would be useful if historical demographers were to search for such data relating to these earlier wars...
  6. doi request reprint Further evidence that some male-based neurodevelopmental disorders are associated with high intrauterine testosterone concentrations
    William H James
    The Galton Laboratory, University College London, Wolfson House, London, UK
    Dev Med Child Neurol 50:15-8. 2008
    ..Provisionally, the data may be interpreted as suggesting that RD may be caused by high intrauterine testosterone levels, and confirming the hypothesis that ADHD is partially caused by high intrauterine testosterone...
  7. ncbi request reprint The validity of Weinberg's Differential Rule
    William H James
    The Galton Laboratory, University College London, London, United Kingdom
    Twin Res Hum Genet 10:771-2. 2007
    ..This is in spite of the fact that one of the premises he used in its derivation is almost certainly, to some extent, false. An explanation is offered here...
  8. ncbi request reprint Are there preconceptional determinants of mammalian sex? A response to Boklage (2005)
    William H James
    The Galton Laboratory, University College London, London, UK
    Hum Reprod 21:2486-90. 2006
    ..Efforts should be made to confirm or discredit these suspicions...
  9. doi request reprint Evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    J Endocrinol 198:3-15. 2008
    ..The purpose of this article is to elicit such comment. Readers are requested to read the accompanying editorial (Clark & Davis 2008) to gain a better perspective of this hypothesis article...
  10. doi request reprint Sex ratios in twin families: commentary on Fellman and Eriksson
    William H James
    The Galton Laboratory, University College London, London, United Kingdom
    Twin Res Hum Genet 11:215-8. 2008
    ..Lastly, appeals are made for (a) data that would test the reliability of the data of Geissler and Lommatsch on the point questioned above, and (b) data on the sex ratios of offspring of twins by the sex and zygosity of the twin parents...
  11. ncbi request reprint Possible constraints on adaptive variation in sex ratio at birth in humans and other primates
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    J Theor Biol 238:383-94. 2006
    ..It seems that gonadal hormones are responsible for adaptive variation; and that maternal adrenal hormones are responsible for maladaptive variation. In evolutionary terms, gonadal hormones precede adrenal hormones...
  12. ncbi request reprint Do celebrities' cosmetic breast augmentations jeopardise their fans' willingness to breast feed?
    William H James
    Galton Laboratory, University College London, 4 Stephenson Way, London, NW1 2HE, UK
    Paediatr Perinat Epidemiol 22:116. 2008
  13. doi request reprint The variances of the distributions of the combinations of the sexes within mammalian litters: notes to mark the centenary of the problem
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    J Theor Biol 259:264-8. 2009
    ..And it is a standard result in probability theory that such variation causes sub-binomial variance...
  14. ncbi request reprint Monitoring reproductive health in Europe: what are the best indicators?
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    Hum Reprod 22:1197-9. 2007
    ..Efforts should be made to assess the sperm quality of volunteer donors in each European country...
  15. ncbi request reprint Potential solutions to problems posed by the offspring sex ratios of people with parasitic and viral infections
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    Folia Parasitol (Praha) 57:114-20. 2010
    ..And if this solution turns out to be correct, it would suggest new endocrine means of combating hepatitis B infection...
  16. doi request reprint The sex ratios of monozygotic and dizygotic twins
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    Twin Res Hum Genet 13:381-2. 2010
    ..Fellman and Eriksson (2010) cited my suggestion that the sex ratio (proportion male) of monozygotic (MZ) twins is lower than that of dizygotic (DZ) twins (James 1975). Here I offer elaborations on and potential explanations for this...
  17. doi request reprint The variations of human sex ratio at birth with time of conception within the cycle, coital rate around the time of conception, duration of time taken to achieve conception, and duration of gestation: a synthesis
    William H James
    Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    J Theor Biol 255:199-204. 2008
    ..Lastly, sex ratio varies substantially with DOG, though the explanation for this is not established: it is suggested that the present treatment provides a testable framework for such an explanation...
  18. ncbi request reprint Further evidence that mammalian sex ratios at birth are partially controlled by parental hormone levels around the time of conception
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    Hum Reprod 19:1250-6. 2004
    ..It is intended that a reader who has read both this paper and my previous paper should be aware of all the data relating to the hypothesis [James WH (1996), J Theor Biol 180, 271-286]...
  19. doi request reprint Behavioural and biological determinants of human sex ratio at birth
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    J Biosoc Sci 42:587-99. 2010
    ..It is noted that the lines of evidence for three hypotheses (James', Manning's and Baron-Cohen's) are mutually supportive...
  20. doi request reprint Further support for the hypothesis that parental hormone levels around the time of conception are associated with human sex ratios at birth
    William H James
    The Galton Laboratory, University College London, UK
    J Biosoc Sci 40:855-61. 2008
    ..It is intended that anyone who has read the present note and my two previous papers (James, 1996, 2004) should be aware of all the data relating to the hypothesis...
  21. ncbi request reprint Offspring sex ratios at birth as markers of paternal endocrine disruption
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2 HE, UK
    Environ Res 100:77-85. 2006
    ....
  22. ncbi request reprint The sexual orientation of men who were brought up in gay or lesbian households
    William H James
    The Galton Laboratory, University College London
    J Biosoc Sci 36:371-4. 2004
    ..Here it is argued that the available data on men raised by same-sex parents cannot validly be interpreted as supporting or refuting this suggestion...
  23. doi request reprint The categories of evidence relating to the hypothesis that mammalian sex ratios at birth are causally related to the hormone concentrations of both parents around the time of conception
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    J Biosoc Sci 43:167-84. 2011
    ..This observational/correlational evidence is tabulated to illustrate its consistency...
  24. doi request reprint Variation of the probability of a male birth within and between sibships
    William H James
    Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, England
    Hum Biol 81:13-22. 2009
    ..Contrary to their inference, a binomial distribution may result when equal and counterbalancing measures of Poisson and Lexis variation are simultaneously present. These conditions are approximately met with respect to human births...
  25. ncbi request reprint Biological and psychosocial determinants of male and female human sexual orientation
    William H James
    The Galton Laboratory, University College London
    J Biosoc Sci 37:555-67. 2005
    ..Methods of testing some of these ideas are presented...
  26. doi request reprint Amendments to hypotheses on the proximate causes of variation in human sex ratios at birth with parental infection with hepatitis B virus or Toxoplasma gondii
    William H James
    The Galton Laboratory, Department of Genetics, Evolution and Environment, University College London, UK
    J Biosoc Sci 43:247-51. 2011
    ..Subsequent research suggests that these hypotheses need amending. A detailed account of the amendments is given elsewhere in a specialized journal (James, 2010a). Here they are summarized...
  27. ncbi request reprint 'Over-ripeness ovopathy, sex ratio increase and sex ratio reversal a challenging hypothesis for sex ratio modulation': an alternative interpretation
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    Hum Reprod 19:775-7. 2004
    ..Finally, it is suggested that there is a circularity in his presentation of his concept of sex ratio 'reversal'...
  28. ncbi request reprint Two hypotheses on the causes of male homosexuality and paedophilia
    William H James
    The Galton Laboratory, University College London
    J Biosoc Sci 38:745-61. 2006
    ..To summarize: most boys who experience CSA do not later develop into homosexuals or paedophiles. However, the available evidence suggests that a few do so as a result of the abuse...
  29. ncbi request reprint The cause(s) of the fraternal birth order effect in male homosexuality
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE
    J Biosoc Sci 36:51-9, 61-2. 2004
    ..Lastly, there seem likely to be causes common to male homosexuality and paedophilia. They may include sexual (or quasi-sexual) experience in childhood or adolescence...
  30. ncbi request reprint Hypotheses on how selection for some traits in rodents led to correlated responses in offspring sex ratios
    William H James
    The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW 1 2HE, UK
    J Theor Biol 228:1-6. 2004
    ..If this line of reasoning were correct, the selection for sex drive would be expected to be accompanied by correlated changes in offspring sex ratio...
  31. doi request reprint Variation of human sex ratios at birth by the sex combinations of the existing sibs, and by reproductive stopping rules: comments on Garenne (2009)
    William H James
    The Galton Laboratory, University College London, UK
    J Biosoc Sci 43:751-60, author reply 761-3. 2011
    ..I suggest that they may reveal it - but do not cause it. Moreover, I suggest that the effects of such stopping rules may be counter-intuitive...
  32. ncbi request reprint Potential of the hormonal hypothesis of sex ratio to explain the unusual sex ratios typical of some malformations
    William H James
    The Galton Laboratory, University College London, Wolfson House, London, England
    Teratology 66:101-2; author reply 103-4. 2002
  33. ncbi request reprint Evidence that intrauterine and postnatal androgens affect the development of pyloric stenosis
    William H James
    Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
    Birth Defects Res A Clin Mol Teratol 70:37-9. 2004
    ..It seemed worth reviewing the epidemiological data on PS in the light of these new developments to see whether this would provide a basis for a plausible hypothesis on these suspected environmental causes of PS...
  34. ncbi request reprint Significance of sib sex ratios in testing the hypothesis that some sex-biased congenital malformations are caused by unusual maternal hormone profiles
    William H James
    Birth Defects Res A Clin Mol Teratol 67:274-5; author reply 273. 2003
  35. ncbi request reprint Testosterone and male fertility in red deer
    William H James
    Science 316:980-1; author reply 980-1. 2007
  36. doi request reprint Re: "Brothers and reduction of the birth weight of later-born siblings"
    William H James
    Am J Epidemiol 168:665; author reply 665-6. 2008
  37. ncbi request reprint The curious negative (protective?) associations between Parkinson's disease and certain behavioral risk factors
    William H James
    Neuroepidemiology 21:305-6. 2002
  38. ncbi request reprint Re: Prostate cancer in fathers with fewer male offspring: the Jerusalem Perinatal Study cohort
    William H James
    J Natl Cancer Inst 99:902; author reply 903-4. 2007
  39. ncbi request reprint Support for a hypothesis on the offspring sex ratios of hepatitis B carriers
    William H James
    J Theor Biol 247:395. 2007
  40. ncbi request reprint Sex ratios of births conceived during wartime
    William H James
    Hum Reprod 18:1133-4. 2003
  41. ncbi request reprint The causes of the excess males among pre-term and post-term births
    William H James
    Hum Reprod 18:655-6. 2003
  42. ncbi request reprint Hormone levels in pre-eclampsia
    William H James
    Acta Obstet Gynecol Scand 81:1152; author reply 1152. 2002
  43. ncbi request reprint Sex ratio of offspring born to men exposed to polychlorinated biphenyls
    William H James
    Lancet 360:1887. 2002
  44. ncbi request reprint Smoking, sperm quality and testosterone level
    William H James
    Hum Reprod 17:3275-6. 2002
  45. ncbi request reprint Periconceptual parental smoking and sex ratio of offspring
    William H James
    Lancet 360:1515; author reply 1515-6. 2002
  46. ncbi request reprint Fish eaters and sex ratio
    William H James
    J Occup Environ Med 44:885-6; author reply 887-8. 2002
  47. ncbi request reprint Birthweight in dizygotic twins
    William H James
    Twin Res 5:309; author reply 10. 2002
  48. ncbi request reprint Is omphalocele a consequence of high maternal estrogen levels?
    William H James
    Teratology 66:59; author reply 60. 2002
  49. pmc Parental exposure to dioxin and offspring sex ratios
    William H James
    Environ Health Perspect 110:A502; discussion A502. 2002
  50. ncbi request reprint Gestation and birthweight in dizygotic twins
    William H James
    Lancet 359:171-2. 2002
  51. ncbi request reprint Response to the "pooling of heterogeneous data"
    William H James
    Fertil Steril 80:680-1. 2003
  52. ncbi request reprint Re: Fetal testosterone and sex differences
    William H James
    Early Hum Dev 84:43. 2008
  53. ncbi request reprint Sex ratios of offspring of patients with breast cancer and other endocrine related cancers
    William H James
    Int J Cancer 119:2710-1; author reply 2712. 2006
  54. ncbi request reprint Fetal sex and intrauterine growth restriction
    William H James
    Am J Obstet Gynecol 195:1498; author reply 1498-9. 2006
  55. ncbi request reprint A further note on the sex ratios of births conceived during wartime
    William H James
    Hum Reprod 19:1495; author reply 1495-6. 2004
  56. pmc The sex ratio of offspring of male gasoline filling station workers
    William H James
    J Epidemiol Community Health 59:339. 2005
  57. ncbi request reprint A hypothesis on the sexual behaviour of men who are destined to develop prostate cancer
    William H James
    Int J Epidemiol 34:483-5. 2005
  58. ncbi request reprint The sex ratio of pregnancies complicated by hospitalisation for hyperemesis gravidarum
    William H James
    BJOG 111:636. 2004
  59. ncbi request reprint Do gonadal hormones confound between parental smoking and offspring sex ratio?
    William H James
    Int J Epidemiol 33:226. 2004
  60. ncbi request reprint Smoking and sex selection?--Not proven yet
    William H James
    Fertil Steril 80:1289; author reply 1290. 2003
  61. ncbi request reprint Food preferences, testosterone concentrations and offspring sex ratios of female mice
    William H James
    Psychoneuroendocrinology 28:1044-5; author reply 1045-6. 2003
  62. ncbi request reprint Evidence that non-ionizing radiation alters men's hormone levels
    William H James
    J Occup Environ Med 44:305-7; author reply 307. 2002