Affiliation: University of Southampton
- B7 costimulation is required for IL-5 and IL-13 secretion by bronchial biopsy tissue of atopic asthmatic subjects in response to allergen stimulationZ Jaffar
University Medicine, Southampton General Hospital, Southampton, United Kingdom, Seattle, Washington
Am J Respir Cell Mol Biol 20:153-62. 1999..This requirement for B7/CD28 costimulation is consistent with the hypothesis that IL-5 and IL-13 are produced by allergen-specific T cells resident in the asthmatic bronchial mucosa...
- The role of CD28-B7 costimulation in allergen-induced cytokine release by bronchial mucosa from patients with moderately severe asthmaJ L Lordan
Respiratory, Cell and Molecular Biology Division, School of Medicine, University of Southampton, Southampton, United Kingdom
J Allergy Clin Immunol 108:976-81. 2001..The different requirements for CD28-mediated costimulation in PBMC cultures and bronchial tissue cultures emphasizes the importance of the tissue microenvironment in pulmonary inflammatory responses in severe asthma...
- Interleukin-5 production by human airway epithelial cellsS Salvi
Department of Medicine, University of Southampton, Southampton, United Kingdom
Am J Respir Cell Mol Biol 20:984-91. 1999....