Kim G Jackson

Summary

Affiliation: University of Reading
Country: UK

Publications

  1. ncbi request reprint Lack of influence of test meal fatty acid composition on the contribution of intestinally-derived lipoproteins to postprandial lipaemia
    K G Jackson
    Centre for Nutrition and Food Safety, School of Biological Sciences, University of Surrey, Guildford, UK
    Br J Nutr 81:51-7. 1999
  2. ncbi request reprint Olive oil increases the number of triacylglycerol-rich chylomicron particles compared with other oils: an effect retained when a second standard meal is fed
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, United Kingdom
    Am J Clin Nutr 76:942-9. 2002
  3. ncbi request reprint Measurement of apolipoprotein B-48 in the Svedberg flotation rate (S(f))>400, S(f) 60-400 and S(f) 20-60 lipoprotein fractions reveals novel findings with respect to the effects of dietary fatty acids on triacylglycerol-rich lipoproteins in postmenopausal
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
    Clin Sci (Lond) 103:227-37. 2002
  4. ncbi request reprint Second meal effect: modified sham feeding does not provoke the release of stored triacylglycerol from a previous high-fat meal
    K G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
    Br J Nutr 85:149-56. 2001
  5. ncbi request reprint The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentrations in middle-aged men and women
    K G Jackson
    Department of Food Science and Technology, University of Reading, UK
    Br J Nutr 82:23-30. 1999
  6. ncbi request reprint Differences in glucose-dependent insulinotrophic polypeptide hormone and hepatic lipase in subjects of southern and northern Europe: implications for postprandial lipemia
    K G Jackson
    Centre for Nutrition and Food Safety, School of Biological Sciences, University of Surrey, United Kingdom
    Am J Clin Nutr 71:13-20. 2000
  7. ncbi request reprint Acute effects of meal fatty acids on postprandial NEFA, glucose and apo E response: implications for insulin sensitivity and lipoprotein regulation?
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, RG6 6AP, UK
    Br J Nutr 93:693-700. 2005
  8. doi request reprint The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion
    Rosalind J Miller
    Department of Food and Nutritional Sciences, University of Reading, Reading, UK
    Mol Nutr Food Res 56:966-75. 2012
  9. doi request reprint A sequential two meal challenge reveals abnormalities in postprandial TAG but not glucose in men with increasing numbers of metabolic syndrome components
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK
    Atherosclerosis 220:237-43. 2012
  10. ncbi request reprint Apolipoprotein E enrichment of immuno-separated chylomicron and chylomicron remnants following saturated fatty acids
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, Berkshire RG6 6AP, UK
    Nutr Metab Cardiovasc Dis 16:405-17. 2006

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Lack of influence of test meal fatty acid composition on the contribution of intestinally-derived lipoproteins to postprandial lipaemia
    K G Jackson
    Centre for Nutrition and Food Safety, School of Biological Sciences, University of Surrey, Guildford, UK
    Br J Nutr 81:51-7. 1999
    ..The value of the two markers in investigating dietary fat absorption and metabolism is discussed...
  2. ncbi request reprint Olive oil increases the number of triacylglycerol-rich chylomicron particles compared with other oils: an effect retained when a second standard meal is fed
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, United Kingdom
    Am J Clin Nutr 76:942-9. 2002
    ..There is a rapid appearance of chylomicrons in the circulation carrying fat ingested with the first meal, with a peak 1 h after the second meal...
  3. ncbi request reprint Measurement of apolipoprotein B-48 in the Svedberg flotation rate (S(f))>400, S(f) 60-400 and S(f) 20-60 lipoprotein fractions reveals novel findings with respect to the effects of dietary fatty acids on triacylglycerol-rich lipoproteins in postmenopausal
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
    Clin Sci (Lond) 103:227-37. 2002
    ....
  4. ncbi request reprint Second meal effect: modified sham feeding does not provoke the release of stored triacylglycerol from a previous high-fat meal
    K G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading RG6 6AP, UK
    Br J Nutr 85:149-56. 2001
    ....
  5. ncbi request reprint The effect of the daily intake of inulin on fasting lipid, insulin and glucose concentrations in middle-aged men and women
    K G Jackson
    Department of Food Science and Technology, University of Reading, UK
    Br J Nutr 82:23-30. 1999
    ....
  6. ncbi request reprint Differences in glucose-dependent insulinotrophic polypeptide hormone and hepatic lipase in subjects of southern and northern Europe: implications for postprandial lipemia
    K G Jackson
    Centre for Nutrition and Food Safety, School of Biological Sciences, University of Surrey, United Kingdom
    Am J Clin Nutr 71:13-20. 2000
    ..This study was an extension of a previous study that showed different lipemic responses to standard test meals in subjects from southern and northern Europe...
  7. ncbi request reprint Acute effects of meal fatty acids on postprandial NEFA, glucose and apo E response: implications for insulin sensitivity and lipoprotein regulation?
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, University of Reading, Reading, RG6 6AP, UK
    Br J Nutr 93:693-700. 2005
    ..PUFA- and MUFA-rich lipoproteins. Elevated Apo E responses to high-SFA meals may have important implications for the hepatic metabolism of triacylglycerol-rich lipoproteins...
  8. doi request reprint The impact of the catechol-O-methyltransferase genotype on vascular function and blood pressure after acute green tea ingestion
    Rosalind J Miller
    Department of Food and Nutritional Sciences, University of Reading, Reading, UK
    Mol Nutr Food Res 56:966-75. 2012
    ..Here, the impact of the catechol-O-methyltransferase (COMT) genotype on vascular function and blood pressure (BP) after green tea extract ingestion are reported...
  9. doi request reprint A sequential two meal challenge reveals abnormalities in postprandial TAG but not glucose in men with increasing numbers of metabolic syndrome components
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK
    Atherosclerosis 220:237-43. 2012
    ..To examine the impact of increasing numbers of metabolic syndrome (MetS) components on postprandial lipaemia...
  10. ncbi request reprint Apolipoprotein E enrichment of immuno-separated chylomicron and chylomicron remnants following saturated fatty acids
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, Berkshire RG6 6AP, UK
    Nutr Metab Cardiovasc Dis 16:405-17. 2006
    ..We examined the effect of meal fatty acids on lipid and apolipoprotein concentrations of very low density lipoprotein (VLDL) and chylomicron/chylomicron remnants in lipid fractions with a Svedberg flotation rate (Sf) 60-400 and Sf 20-60...
  11. doi request reprint Dietary fat manipulation has a greater impact on postprandial lipid metabolism than the apolipoprotein E (epsilon) genotype-insights from the SATgenĪµ study
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK
    Mol Nutr Food Res 56:1761-70. 2012
    ..Our aim was to determine the effects of chronic dietary fat manipulation on postprandial lipaemia according to apolipoprotein (APO)E genotype...
  12. doi request reprint A preliminary investigation of the impact of catechol-O-methyltransferase genotype on the absorption and metabolism of green tea catechins
    Rosalind J Miller
    Department of Food and Nutritional Sciences, University of Reading, PO Box 226, Whiteknights, Reading, Berkshire RG6 6AP, UK
    Eur J Nutr 51:47-55. 2012
    ..The current preliminary study was designed to investigate the impact of COMT genotype on green tea catechin absorption and metabolism in humans...
  13. doi request reprint Interactions between age and apoE genotype on fasting and postprandial triglycerides levels
    Andrew L Carvalho-Wells
    Department of Food and Nutritional Sciences and Institute of Cardiovascular and Metabolic Research, University of Reading, Reading RG6 6AP, UK
    Atherosclerosis 212:481-7. 2010
    ..Here the impact of the common apolipoprotein (apo)E epsilon mutation on the postprandial triglyceride (TG) response is determined, along with an assessment of genotype penetrance according to age, body mass index and gender...
  14. doi request reprint DHA-rich fish oil reverses the detrimental effects of saturated fatty acids on postprandial vascular reactivity
    Katie J Newens
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, United Kingdom
    Am J Clin Nutr 94:742-8. 2011
    ..Experimental elevation of nonesterified fatty acids (NEFAs) impairs endothelial function, but the effect of NEFA composition is unknown...
  15. ncbi request reprint Saturated fat-induced changes in Sf 60-400 particle composition reduces uptake of LDL by HepG2 cells
    Kim G Jackson
    School of Food Biosciences, University of Reading, Reading, Berkshire, United Kingdom
    J Lipid Res 47:393-403. 2006
    ..008). In conclusion, these findings suggest an alternative or additional mechanism whereby acute fat ingestion can influence LDL clearance via competitive apoE-dependent effects of TRL on the LDL receptor...
  16. doi request reprint Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers
    David Vauzour
    Molecular Nutrition Group, School of Chemistry, Food and Pharmacy, University of Reading, Reading, UK
    Br J Nutr 103:1168-78. 2010
    ..Our data suggest that a daily moderate consumption of Champagne wine may improve vascular performance via the delivery of phenolic constituents capable of improving NO bioavailability and reducing matrix metalloproteinase activity...
  17. doi request reprint The leptin receptor Gln223Arg polymorphism (rs1137101) mediates the postprandial lipaemic response, but only in males
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research, PO Box 226, Whiteknights, University of Reading, Reading RG6 6AP, UK
    Atherosclerosis 225:135-41. 2012
    ....
  18. doi request reprint APOE genotype influences triglyceride and C-reactive protein responses to altered dietary fat intake in UK adults
    Andrew L Carvalho-Wells
    Hugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research, Department of Food and Nutritional Sciences, University of Reading, Reading, United Kingdom
    Am J Clin Nutr 96:1447-53. 2012
    ..The response of plasma lipids to dietary fat manipulation is highly heterogeneous, with some indications that APOE genotype may be important...
  19. doi request reprint SATgenĪµ dietary model to implement diets of differing fat composition in prospectively genotyped groups (apoE) using commercially available foods
    Stacey Lockyer
    Hugh Sinclair Unit of Human Nutrition and Institute for Cardiovascular and Metabolic Research, Department of Food and Nutritional Sciences, University of Reading, Whiteknights Campus, Reading, UK
    Br J Nutr 108:1705-13. 2012
    ..In summary, the dietary strategy was successfully implemented in a free-living population resulting in well-tolerated diets which broadly met the dietary targets set...
  20. pmc Glu298Asp polymorphism influences the beneficial effects of fish oil fatty acids on postprandial vascular function
    Abby K Thompson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, RG6 6AP, UK
    J Lipid Res 53:2205-13. 2012
    ..Effects of fat composition appear to be genotype and gender dependent, with the greatest difference in vasodilatory response to the two fat loads seen in the Asp298 females...
  21. doi request reprint The impact of age on the postprandial vascular response to a fish oil-enriched meal
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food Biosciences, University of Reading, PO Box 226, Whiteknights, Reading RG6 6AP, UK
    Br J Nutr 102:1414-9. 2009
    ..In conclusion, the ingestion of a meal enriched in fish oil fatty acids was shown to improve postprandial vascular reactivity at 4 h in our younger men, with little benefit evident in our older men...
  22. doi request reprint Impact of saturated, polyunsaturated and monounsaturated fatty acid-rich micelles on lipoprotein synthesis and secretion in Caco-2 cells
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading, RG6 6AP, UK
    Lipids 44:1081-9. 2009
    ..Our electron micrographs are suggestive that some endocytotic uptake of MUFA-rich taurocholate micelles may promote greater lipoprotein synthesis and secretion in Caco-2 cells...
  23. ncbi request reprint Exaggerated postprandial lipaemia and lower post-heparin lipoprotein lipase activity in middle-aged men
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Whiteknights, Reading RG6 6AP, UK
    Clin Sci (Lond) 105:457-66. 2003
    ..Alternatively, post-heparin lipase activities may not be good markers for the insulin-sensitive component of lipase that is activated postprandially...
  24. doi request reprint The impact of the catechol-O-methyltransferase genotype on the acute responsiveness of vascular reactivity to a green tea extract
    Rosalind J Miller
    Department of Food and Nutritional Sciences, University of Reading, Whiteknights, PO Box 226, Reading, Berkshire RG6 6AP, UK
    Br J Nutr 105:1138-44. 2011
    ..In conclusion, SI and insulin response to the glucose load differed between the COMT genotype groups, and this may be suggestive of a green tea extract and genotype interaction...
  25. doi request reprint Acute effects of elevated NEFA on vascular function: a comparison of SFA and MUFA
    Katie J Newens
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK
    Br J Nutr 105:1343-51. 2011
    ..More studies are needed to fully investigate the impact of NEFA composition on risk factors for CVD...
  26. doi request reprint Greater impairment of postprandial triacylglycerol than glucose response in metabolic syndrome subjects with fasting hyperglycaemia
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading RG6 6AP, UK
    Metabolism 62:1065-9. 2013
    ..Our aim was to examine the impact of the presence of raised fasting glucose as a MetS component on postprandial lipaemia...
  27. ncbi request reprint Fish oil fatty acids improve postprandial vascular reactivity in healthy men
    Christopher K Armah
    Hugh Sinclair Unit of Human Nutrition, Department of Food Biosciences, University of Reading, Reading RG6 6AP, UK
    Clin Sci (Lond) 114:679-86. 2008
    ..03). In conclusion, meal fatty acids appear to be an important determinant of vascular reactivity, with fish oils significantly improving postprandial endothelium-independent vasodilation...
  28. doi request reprint Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food Biosciences, University of Reading, Reading, United Kingdom
    Atherosclerosis 208:246-52. 2010
    ..To examine the impact of age and the natural menopause on the postprandial triacylglycerol (TAG) response in healthy women...
  29. ncbi request reprint Differences in cell morphology, lipid and apo B secretory capacity in caco-2 cells following long term treatment with saturated and monounsaturated fatty acids
    Paul A Bateman
    Hugh Sinclair Unit of Human Nutrition, Department of Food Biosciences, School of Chemistry, Food Biosciences and Pharmacy, The University of Reading, Reading Berkshire, UK
    Biochim Biophys Acta 1771:475-85. 2007
    ..In conclusion, previously reported differences in lipoprotein secretion by caco-2 cells supplemented with saturated fatty acids (SFA) and OA may partly reflect early cytotoxic effects of SFA on cellular integrity and function...
  30. ncbi request reprint Greater enrichment of triacylglycerol-rich lipoproteins with apolipoproteins E and C-III after meals rich in saturated fatty acids than after meals rich in unsaturated fatty acids
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, UK
    Am J Clin Nutr 81:25-34. 2005
    ....
  31. doi request reprint Postprandial lipemia and cardiovascular disease risk: Interrelationships between dietary, physiological and genetic determinants
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, UK
    Atherosclerosis 220:22-33. 2012
    ..Finally, we highlight the need for the development of a standardised 'fat tolerance test' for use in clinical trials, to allow the integration and comparison of data from individual studies...
  32. doi request reprint A review of the evidence for the effects of total dietary fat, saturated, monounsaturated and n-6 polyunsaturated fatty acids on vascular function, endothelial progenitor cells and microparticles
    Katerina Vafeiadou
    Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Reading, UK
    Br J Nutr 107:303-24. 2012
    ....
  33. doi request reprint Influence of apoA-V gene variants on postprandial triglyceride metabolism: impact of gender
    Estibaliz Olano-Martin
    Hugh Sinclair Human Nutrition Group, School of Chemistry, Food Biosciences, and Pharmacy, University of Reading, Reading RG6 6AP, United Kingdom
    J Lipid Res 49:945-53. 2008
    ..015). However, in linear regression analysis, a significant independent association with TG AUC (P = 0.007) was only evident for the apoA-V -1131 T>C SNP, indicating a greater relative importance of the apoA-V genotype...
  34. ncbi request reprint Apolipoprotein B-48: comparison of fasting concentrations measured in normolipidaemic individuals using SDS-PAGE, immunoblotting and ELISA
    Kim G Jackson
    Hugh Sinclair Unit of Human Nutrition, School of Food Biosciences, The University of Reading, Reading, Berkshire, UK
    Atherosclerosis 176:207-17. 2004
    ..A high degree of variability was observed in the apo B-48 concentrations reported in the literature both within and between the SDS-PAGE, immunoblotting and ELISA methods...
  35. doi request reprint Determination of the in vivo prebiotic potential of a maize-based whole grain breakfast cereal: a human feeding study
    Andrew L Carvalho-Wells
    Nutrition Research Group, Department of Food and Nutritional Sciences, School of Chemistry, Food and Pharmacy, University of Reading, Reading RG6 6AP, UK
    Br J Nutr 104:1353-6. 2010
    ..In conclusion, this WG maize-enriched breakfast cereal mediated a bifidogenic modulation of the gut microbiota, indicating a possible prebiotic mode of action...
  36. doi request reprint Green tea (Camellia sinensis) catechins and vascular function
    Rosalind J Moore
    Department of Food Biosciences, University of Reading, Whiteknights, Reading, UK
    Br J Nutr 102:1790-802. 2009
    ..Further studies in animal and cell models using physiological concentrations of catechins and their metabolites are warranted in order to gain some insight into the physiology and molecular basis of the observed beneficial effects...
  37. ncbi request reprint Acute ingestion of a meal rich in n-3 polyunsaturated fatty acids results in rapid gastric emptying in humans
    M Denise Robertson
    Oxford Centre for Diabetes, Endocrinology and Metabolism, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
    Am J Clin Nutr 76:232-8. 2002
    ..The effects on atherosclerosis may be partly mediated by the observed reduction in fasting and postprandial triacylglycerol concentrations after both acute and chronic n-3 PUFA ingestion...