Ana Izcue

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Regulatory lymphocytes and intestinal inflammation
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK
    Annu Rev Immunol 27:313-38. 2009
  2. ncbi Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo
    Simon Read
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, United Kingdom
    J Immunol 177:4376-83. 2006
  3. ncbi Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis
    Holm H Uhlig
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    J Immunol 177:5852-60. 2006
  4. ncbi Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    Immunity 28:559-70. 2008
  5. ncbi Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunol Rev 212:256-71. 2006
  6. ncbi Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunology 123:6-10. 2008
  7. ncbi The interleukin-23 axis in intestinal inflammation
    Philip P Ahern
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunol Rev 226:147-59. 2008
  8. ncbi Prenatal tolerance--a role for regulatory T cells?
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Eur J Immunol 35:379-82. 2005

Collaborators

Detail Information

Publications8

  1. ncbi Regulatory lymphocytes and intestinal inflammation
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, OX1 3RE, UK
    Annu Rev Immunol 27:313-38. 2009
    ....
  2. ncbi Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo
    Simon Read
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, United Kingdom
    J Immunol 177:4376-83. 2006
    ..This role has to be taken into account when targeting CTLA-4 for therapeutic purposes, as such a strategy will not only boost effector T cell responses, but might also break T(R)-mediated self-tolerance...
  3. ncbi Characterization of Foxp3+CD4+CD25+ and IL-10-secreting CD4+CD25+ T cells during cure of colitis
    Holm H Uhlig
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    J Immunol 177:5852-60. 2006
    ....
  4. ncbi Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    Immunity 28:559-70. 2008
    ..Taken together, our data indicate that overriding immunosuppressive pathways is an important function of IL-23 in the intestine and could influence not only Th17 cell activity but also other types of immune responses...
  5. ncbi Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunol Rev 212:256-71. 2006
    ..Further understanding of the factors that control the activity of Tregs in different immune compartments may facilitate the design of strategies to target regulation in a tissue-specific way...
  6. ncbi Special regulatory T-cell review: Regulatory T cells and the intestinal tract--patrolling the frontier
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunology 123:6-10. 2008
    ..In this review, we briefly discuss the historical background leading to the identification of Foxp3+ Treg and give an overview of their role in controlling systemic and mucosal immune responses...
  7. ncbi The interleukin-23 axis in intestinal inflammation
    Philip P Ahern
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Immunol Rev 226:147-59. 2008
    ..Here we discuss the dual roles of IL-23 in intestinal immunity and how IL-23 and downstream effector pathways may make novel targets for the treatment of IBD...
  8. ncbi Prenatal tolerance--a role for regulatory T cells?
    Ana Izcue
    Sir William Dunn School of Pathology, University of Oxford, Oxford, UK
    Eur J Immunol 35:379-82. 2005
    ....