Research Topics
| Elizabeth B IsaacsSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Double-blind, randomized trial of long-chain polyunsaturated fatty acid supplementation in formula fed to preterm infantsMary S Fewtrell
MRC Childhood Nutrition Research Center, Institute of Child Health, London, United Kingdom
Pediatrics 110:73-82. 2002....
Early diet and general cognitive outcome at adolescence in children born at or below 30 weeks gestationElizabeth B Isaacs
Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK
J Pediatr 155:229-34. 2009..To test the hypothesis that effects of early diet on cognition observed at age 8 years persist in adolescents born preterm at < or = 30 weeks gestational age...
Impact of breast milk on intelligence quotient, brain size, and white matter developmentElizabeth B Isaacs
Childhood Nutrition Research Centre and Radiology and Physics Unit, University College London Institute of Child Health, and Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, United Kingdom
Pediatr Res 67:357-62. 2010..The selective effect in males accords with animal and human evidence regarding gender effects of early diet. Our data have important neurobiological and public health implications and identify areas for future mechanistic study...
10-year cognition in preterms after random assignment to fatty acid supplementation in infancyElizabeth B Isaacs
Medical Research Council Childhood Nutrition Research Centre, University College London Institute of Child Health, London, England
Pediatrics 128:e890-8. 2011..To test the hypothesis that long-chain polyunsaturated fatty acid (LCPUFA) supplementation in infancy would improve cognition into later childhood (after 9 years) at both general and specific levels...
The effect of early human diet on caudate volumes and IQElizabeth B Isaacs
MRC Childhood Nutrition Research Centre, University College London Institute of Child Health, London WC1N 1EH, United Kingdom
Pediatr Res 63:308-14. 2008..Our findings may partly explain the effects of early diet on cognition and the predominant effects in males. They are among the first to show that human brain structure can be influenced by early nutrition...
Brain morphometry and IQ measurements in preterm childrenE B Isaacs
MRC Childhood Nutrition Research Centre, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain 127:2595-607. 2004..Whether this is true of children born at >30 weeks gestation and what other factors predispose to this decline have yet to be determined...
Cortical anomalies associated with visuospatial processing deficitsElizabeth B Isaacs
MRC Childhood Nutrition Research Centre, Institute of Child Health, University College, London, United Kingdom
Ann Neurol 53:768-73. 2003..We suggest that these anomalies of cortical architecture relate to impaired performance on the line orientation task...
Calculation difficulties in children of very low birthweight: a neural correlateE B Isaacs
MRC Childhood Nutrition Research Centre and Radiology and Physics Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain 124:1701-7. 2001..To our knowledge, this is the first report establishing a structural neural correlate of calculation ability in a group of neurologically normal individuals...
The 10-year follow-up of a randomised trial of long-chain polyunsaturated fatty acid supplementation in preterm infants: effects on growth and blood pressureKathy Kennedy
MRC Childhood Nutrition Research Centre, UCL Institute of Child Health, London, UK
Arch Dis Child 95:588-95. 2010..To test the hypothesis that consumption of infant formulas containing long-chain polyunsaturated fatty acids (LCPUFAs) by preterm infants would favourably influence growth, body composition and blood pressure (BP) at age 10 years...
The effect of intrauterine growth on verbal IQ scores in childhood: a study of monozygotic twinsCaroline J Edmonds
Medical Research Council, Childhood Nutrition Research Centre, Institute of Child Health, University College London, London, United Kingdom
Pediatrics 126:e1095-101. 2010....
Aluminum exposure from parenteral nutrition in preterm infants: bone health at 15-year follow-upMary S Fewtrell
Medical Research Council Childhood Nutrition Research Centre, University College London Institute of Child Health, London, United Kingdom
Pediatrics 124:1372-9. 2009..Here, in the same cohort, we test the hypothesis that neonatal aluminum exposure also adversely affects long-term bone health, as indicated by reduced bone mass...
Intelligence after stroke in childhood: review of the literature and suggestions for future researchA M Hogan
Cognitive Neurosciences Unit, Institute of Child Health, University College London Medical School, UK
J Child Neurol 15:325-32. 2000..Some suggestions for future research are highlighted in order to encourage further consideration of the issues raised here...
Low plasma taurine and later neurodevelopmentB A Wharton
Childhood Nutrition Research Centre, Institute of Child Health, London WC1 1EH, UK
Arch Dis Child Fetal Neonatal Ed 89:F497-8. 2004..Low plasma neonatal taurine was associated with lower scores on the Bayley mental development index at 18 months and the WISC-R arithmetic subtest at 7 years. Currently it is not mandatory to add taurine to infant formulas...
Developmental amnesia and its relationship to degree of hippocampal atrophyE B Isaacs
Institute of Child Health, University College London, London WC1N 1EH, United Kingdom
Proc Natl Acad Sci U S A 100:13060-3. 2003..Whether this is a sufficient condition for the disorder or whether abnormality in other brain regions is also necessary remains to be determined...
Intellectual decline in children with moyamoya and sickle cell anaemiaA M Hogan
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London and Great Ormond Street Hospital for Children, London, UK
Dev Med Child Neurol 47:824-9. 2005..While the reduction in IQ attributed to SCA does not appear to become more marked with increasing age, the difference between those with and without MMS is associated with increasing effect over time...
