W N Hunter
Affiliation: University of Dundee
- Hunter W. The non-mevalonate pathway of isoprenoid precursor biosynthesis. J Biol Chem. 2007;282:21573-7 pubmed..Detailed knowledge of the pathway may also be exploited to genetically modify microorganisms and plants to produce compounds of agricultural and medical interest. ..
- O Rourke P, Kalinowska Tłuścik J, Fyfe P, Dawson A, Hunter W. Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment. BMC Struct Biol. 2014;14:1 pubmed publisher..The high degree of structural conservation in and around the IspF active site suggests that any structural model might be suitable to support a program of structure-based drug discovery. ..
- Zoltner M, Ng W, Money J, Fyfe P, Kneuper H, Palmer T, et al. EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system. Biochem J. 2016;473:1941-52 pubmed publisher....