Mark D Humphries

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. ncbi request reprint Solution methods for a new class of simple model neurons
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Neural Comput 19:3216-25. 2007
  2. doi request reprint The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, S10 2TN, UK
    Prog Neurobiol 90:385-417. 2010
  3. doi request reprint Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, UK
    Neural Netw 22:1174-88. 2009
  4. pmc Network 'small-world-ness': a quantitative method for determining canonical network equivalence
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, United Kingdom
    PLoS ONE 3:e0002051. 2008
  5. pmc Is there a brainstem substrate for action selection?
    M D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Philos Trans R Soc Lond B Biol Sci 362:1627-39. 2007
  6. pmc The brainstem reticular formation is a small-world, not scale-free, network
    M D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Proc Biol Sci 273:503-11. 2006
  7. pmc Reconstructing the three-dimensional GABAergic microcircuit of the striatum
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, United Kingdom
    PLoS Comput Biol 6:e1001011. 2010
  8. ncbi request reprint A robot model of the basal ganglia: behavior and intrinsic processing
    Tony J Prescott
    Adaptive Behavior Research Group, Department of Psychology, University of Sheffield, Sheffield, Western Bank, South Yorkshire, Sheffield S10 2TN, UK
    Neural Netw 19:31-61. 2006
  9. ncbi request reprint A physiologically plausible model of action selection and oscillatory activity in the basal ganglia
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, S10 2TP, United Kingdom
    J Neurosci 26:12921-42. 2006
  10. ncbi request reprint The role of intra-thalamic and thalamocortical circuits in action selection
    M D Humphries
    Department of Psychology, University of Sheffield, UK
    Network 13:131-56. 2002

Detail Information

Publications13

  1. ncbi request reprint Solution methods for a new class of simple model neurons
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Neural Comput 19:3216-25. 2007
    ..The model was surprisingly simple yet able to accurately replicate the firing patterns of different types of cortical cell. Here, we derive a solution method that allows efficient simulation of the model...
  2. doi request reprint The ventral basal ganglia, a selection mechanism at the crossroads of space, strategy, and reward
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, S10 2TN, UK
    Prog Neurobiol 90:385-417. 2010
    ....
  3. doi request reprint Dopamine-modulated dynamic cell assemblies generated by the GABAergic striatal microcircuit
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, UK
    Neural Netw 22:1174-88. 2009
    ..Such small cell assemblies forming spontaneously only in the absence of dopamine may contribute to motor control problems seen in humans and animals following a loss of dopamine cells...
  4. pmc Network 'small-world-ness': a quantitative method for determining canonical network equivalence
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, United Kingdom
    PLoS ONE 3:e0002051. 2008
    ..However, the process of establishing an equivalent WS model is imprecise and there is a pressing need to discover ways in which this equivalence may be quantified...
  5. pmc Is there a brainstem substrate for action selection?
    M D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Philos Trans R Soc Lond B Biol Sci 362:1627-39. 2007
    ..Finally, we consider the potential integration of the basal ganglia and mRF substrates for selection and suggest that they may collectively form a layered/hierarchical control system...
  6. pmc The brainstem reticular formation is a small-world, not scale-free, network
    M D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Proc Biol Sci 273:503-11. 2006
    ..We conclude that the medial RF is configured to create small-world (implying coherent rapid-processing capabilities), but not scale-free, type networks under assumptions which are amenable to quantitative measurement...
  7. pmc Reconstructing the three-dimensional GABAergic microcircuit of the striatum
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, United Kingdom
    PLoS Comput Biol 6:e1001011. 2010
    ..Our models thus intimately link striatal micro-anatomy to its dynamics, providing a biologically grounded platform for further study...
  8. ncbi request reprint A robot model of the basal ganglia: behavior and intrinsic processing
    Tony J Prescott
    Adaptive Behavior Research Group, Department of Psychology, University of Sheffield, Sheffield, Western Bank, South Yorkshire, Sheffield S10 2TN, UK
    Neural Netw 19:31-61. 2006
    ..The model is shown to cast light on recent neurobiological findings concerning behavioral switching and sequencing...
  9. ncbi request reprint A physiologically plausible model of action selection and oscillatory activity in the basal ganglia
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield, S10 2TP, United Kingdom
    J Neurosci 26:12921-42. 2006
    ....
  10. ncbi request reprint The role of intra-thalamic and thalamocortical circuits in action selection
    M D Humphries
    Department of Psychology, University of Sheffield, UK
    Network 13:131-56. 2002
    ..Thus, we conclude that the results are consistent with these structures having clearly defined functions in action selection...
  11. pmc Capturing dopaminergic modulation and bimodal membrane behaviour of striatal medium spiny neurons in accurate, reduced models
    Mark D Humphries
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield Sheffield, UK
    Front Comput Neurosci 3:26. 2009
    ..More importantly, these provide a tractable framework for further study of dopamine's effects on computation by individual neurons...
  12. doi request reprint Network effects of subthalamic deep brain stimulation drive a unique mixture of responses in basal ganglia output
    Mark D Humphries
    Group for Neural Theory, Department d Etudes Cognitives, Ecole Normale Superieure, 29 rue d Ulm, 75005 Paris, France
    Eur J Neurosci 36:2240-51. 2012
    ....
  13. ncbi request reprint A pulsed neural network model of bursting in the basal ganglia
    M D Humphries
    Department of Psychology, University of Sheffield, UK
    Neural Netw 14:845-63. 2001
    ..Third, that a variety of dendritic processing is necessary in order to obtain the full range of bursting behaviour...