Claire Hughes

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Executive function and theory of mind: Predictive relations from ages 2 to 4
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, England
    Dev Psychol 43:1447-59. 2007
  2. doi request reprint Tracking executive function across the transition to school: a latent variable approach
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, United Kingdom
    Dev Neuropsychol 35:20-36. 2010
  3. doi request reprint Does maternal depression predict young children's executive function? - a 4-year longitudinal study
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, UK
    J Child Psychol Psychiatry 54:169-77. 2013
  4. doi request reprint Individual differences in false belief understanding are stable from 3 to 6 years of age and predict children's mental state talk with school friends
    Claire Hughes
    Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK
    J Exp Child Psychol 108:96-112. 2011
  5. ncbi request reprint Acting nasty in the face of failure? Longitudinal observations of "hard-to-manage" children playing a rigged competitive game with a friend
    C Hughes
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, United Kingdom
    J Abnorm Child Psychol 29:403-16. 2001
  6. ncbi request reprint Positive and protective: effects of early theory of mind on problem behaviors in at-risk preschoolers
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 48:1025-32. 2007
  7. ncbi request reprint 'I'm gonna beat you!' SNap!: an observational paradigm for assessing young children's disruptive behaviour in competitive play
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 43:507-16. 2002
  8. ncbi request reprint Origins of individual differences in theory of mind: from nature to nurture?
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    Child Dev 76:356-70. 2005
  9. ncbi request reprint Executive function and theory of mind in 2 year olds: a family affair?
    Claire Hughes
    Centre for Family Research, University of Cambridge, England
    Dev Neuropsychol 28:645-68. 2005
  10. ncbi request reprint Behavioural problems in 2-year-olds: links with individual differences in theory of mind, executive function and harsh parenting
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 47:488-97. 2006

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Executive function and theory of mind: Predictive relations from ages 2 to 4
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, England
    Dev Psychol 43:1447-59. 2007
    ..The findings provide only partial support for the view that ToM is a prerequisite for EF but stronger support for the proposal that EF facilitates children's performance on ToM tasks...
  2. doi request reprint Tracking executive function across the transition to school: a latent variable approach
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, United Kingdom
    Dev Neuropsychol 35:20-36. 2010
    ..Across the transition to school, less able children (but not children from low income families) showed greater gains in EF than their peers...
  3. doi request reprint Does maternal depression predict young children's executive function? - a 4-year longitudinal study
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge, UK
    J Child Psychol Psychiatry 54:169-77. 2013
    ....
  4. doi request reprint Individual differences in false belief understanding are stable from 3 to 6 years of age and predict children's mental state talk with school friends
    Claire Hughes
    Centre for Family Research, University of Cambridge, Free School Lane, Cambridge CB2 3RF, UK
    J Exp Child Psychol 108:96-112. 2011
    ..We conclude that preschoolers' false belief understanding both directly and indirectly supports children's growing ability to discuss thoughts and feelings in their conversations with friends...
  5. ncbi request reprint Acting nasty in the face of failure? Longitudinal observations of "hard-to-manage" children playing a rigged competitive game with a friend
    C Hughes
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, United Kingdom
    J Abnorm Child Psychol 29:403-16. 2001
    ..These findings highlight just a few of the multiple paths leading to peer problems among children with disruptive behavior problems...
  6. ncbi request reprint Positive and protective: effects of early theory of mind on problem behaviors in at-risk preschoolers
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 48:1025-32. 2007
    ..This study examined whether these age-2 measures also predict age-4 problem behaviors...
  7. ncbi request reprint 'I'm gonna beat you!' SNap!: an observational paradigm for assessing young children's disruptive behaviour in competitive play
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 43:507-16. 2002
    ..Recent work suggests that this paradigm is useful for assessing disruptive behaviour in young children (Hughes, Cutting, & Dunn, 2001)...
  8. ncbi request reprint Origins of individual differences in theory of mind: from nature to nurture?
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    Child Dev 76:356-70. 2005
    ..Possible underlying proximal mechanisms are discussed, including maternal speech and mind-mindedness, sibling interactions, and peer influences...
  9. ncbi request reprint Executive function and theory of mind in 2 year olds: a family affair?
    Claire Hughes
    Centre for Family Research, University of Cambridge, England
    Dev Neuropsychol 28:645-68. 2005
    ..In contrast, positive sibling relationships predicted significant variance in ToM, even controlling for age, verbal ability, EF, social disadvantage, and parent-child relationships...
  10. ncbi request reprint Behavioural problems in 2-year-olds: links with individual differences in theory of mind, executive function and harsh parenting
    Claire Hughes
    Centre for Family Research, University of Cambridge, UK
    J Child Psychol Psychiatry 47:488-97. 2006
    ..Cognitive and family factors are implicated in the origins of behavioural problems, but little is known about their independence or interplay...
  11. ncbi request reprint Does executive function matter for preschoolers' problem behaviors?
    Claire Hughes
    Centre for Family Research, University of Cambridge, Free School Lane, Cambridge, CB2 3RF, UK
    J Abnorm Child Psychol 36:1-14. 2008
    ..In addition, age-3 EF mediated relations between age-2 verbal ability and age-4 problem behaviors...
  12. doi request reprint Individual differences in growth in executive function across the transition to school predict externalizing and internalizing behaviors and self-perceived academic success at 6 years of age
    Claire Hughes
    Centre for Family Research, University of Cambridge, Cambridge CB2 3RF, UK
    J Exp Child Psychol 108:663-76. 2011
    ..These findings underscore the clinical and educational significance of early individual differences in EF and highlight the value of adopting a developmental perspective...
  13. doi request reprint Gender differences in children's problem behaviours in competitive play with friends
    Rosie Ensor
    Centre for Family Research, University of Cambridge, UK
    Br J Dev Psychol 29:176-87. 2011
    ..In addition, the association between the latent factor and teachers' ratings of total difficulties was significantly stronger for boys than girls...
  14. doi request reprint Trajectories of antisocial behaviour towards siblings predict antisocial behaviour towards peers
    Rosie Ensor
    Centre for Family Research, University of Cambridge, Free School Lane, Cambridge, UK
    J Child Psychol Psychiatry 51:1208-16. 2010
    ..Young siblings' antisocial behaviour is common yet its impact has received relatively little research attention...
  15. pmc Flagellin polymerisation control by a cytosolic export chaperone
    F Auvray
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    J Mol Biol 308:221-9. 2001
    ..Compatible with this view, FliS was able to prevent in vitro polymerisation of FliC into filaments...
  16. ncbi request reprint Executive function deficits in autism spectrum disorders and attention-deficit/hyperactivity disorder: examining profiles across domains and ages
    Francesca Happe
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
    Brain Cogn 61:25-39. 2006
    ..Within the present groups, the overall findings suggested less severe and persistent EF deficits in ASD (including Asperger Syndrome) than in ADHD...
  17. doi request reprint Content or connectedness? Mother-child talk and early social understanding
    Rosie Ensor
    Centre for Family Research, Free School Lane, Cambridge, CB2 3RF, United Kingdom
    Child Dev 79:201-16. 2008
    ..Connected conversations provide a fertile context for children's developing social understanding...
  18. ncbi request reprint Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
    J P Issartel
    Department of Pathology, University of Cambridge, UK
    Nature 351:759-61. 1991
    ..Only acyl carrier protein, not acyl-CoA, can promote HlyC-directed proHlyA acylation, but a range of acyl groups are effective...
  19. ncbi request reprint Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
    V Koronakis
    Department of Pathology, University of Cambridge, UK
    Nature 405:914-9. 2000
    ..The structure provides an explanation of how the cell cytosol is connected to the external environment during export, and suggests a general mechanism for the action of bacterial efflux pumps...
  20. pmc Disentangling weak coherence and executive dysfunction: planning drawing in autism and attention-deficit/hyperactivity disorder
    Rhonda Booth
    Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, DeCrespigny Park, Denmark Hill, London SE5 8AF, UK
    Philos Trans R Soc Lond B Biol Sci 358:387-92. 2003
    ..These findings indicate that weak coherence may indeed be a cognitive style specific to autism and unrelated to cognitive deficits in frontal functions...
  21. ncbi request reprint In vitro recruitment of the RfaH regulatory protein into a specialised transcription complex, directed by the nucleic acid ops element
    M J Bailey
    Department of Pathology, University of Cambridge, UK
    Mol Gen Genet 262:1052-9. 2000
    ..The data confirm that the ops element directs recruitment of RfaH into a multi-component RNA polymerase complex that resists transcription termination...
  22. doi request reprint Silent films and strange stories: theory of mind, gender, and social experiences in middle childhood
    Rory T Devine
    Department of Psychology, University of Cambridge, Cambridge, UK
    Child Dev 84:989-1003. 2013
    ..Girls outperformed boys on the theory-of-mind latent factor, and the correlates of individual differences in theory of mind were gender specific: Low scores were related to loneliness in girls and to peer rejection in boys...
  23. ncbi request reprint A gene, yaeQ, that suppresses reduced operon expression caused by mutations in the transcription elongation gene rfaH in Escherichia coli and Salmonella typhimurium
    K R Wong
    Department of Pathology, University of Cambridge, UK
    Mol Gen Genet 257:693-6. 1998
    ..YaeQ also complements a rfaH::Tn5 null mutation, indicating that it compensates for loss of RfaH function without interaction between the two proteins...
  24. pmc Acylation of Escherichia coli hemolysin: a unique protein lipidation mechanism underlying toxin function
    P Stanley
    Department of Pathology, University of Cambridge, Cambridge CB2 1QP, United Kingdom
    Microbiol Mol Biol Rev 62:309-33. 1998
    ....
  25. ncbi request reprint An ordered reaction mechanism for bacterial toxin acylation by the specialized acyltransferase HlyC: formation of a ternary complex with acylACP and protoxin substrates
    P Stanley
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Mol Microbiol 34:887-901. 1999
    ....
  26. ncbi request reprint Channel-tunnels
    V Koronakis
    Department of Pathology, Cambridge University, Tennis Court Road, Cambridge CB2 1QP, UK
    Curr Opin Struct Biol 11:403-7. 2001
    ..The 'channel-tunnel' is closed at its periplasmic entrance, but can be opened by an 'iris-like' mechanism when recruited by substrate-engaged proteins in the cytosolic membrane...
  27. ncbi request reprint Functions of the subunits in the FlhD(2)C(2) transcriptional master regulator of bacterial flagellum biogenesis and swarming
    L Claret
    Department of Pathology, Cambridge University, Tennis Court Road, Cambridge, CB2 1QP, UK
    J Mol Biol 303:467-78. 2000
    ..FlhD(2)C(2)is therefore an atypical prokaryotic transcription activator in which interaction of the FlhC subunit with DNA target sequences is enhanced by the coexpressed helper subunit FlhD...
  28. ncbi request reprint RfaH and the ops element, components of a novel system controlling bacterial transcription elongation
    M J Bailey
    Department of Pathology, University of Cambridge, UK
    Mol Microbiol 26:845-51. 1997
    ....
  29. ncbi request reprint Increased distal gene transcription by the elongation factor RfaH, a specialized homologue of NusG
    M J Bailey
    Department of Pathology, University of Cambridge, UK
    Mol Microbiol 22:729-37. 1996
    ..We suggest that RfaH directs transcript elongation in an analogous way to NusG, but does so in a subset of bacterial operons primarily engaged in the production of extracellular components required for virulence and fertility...
  30. ncbi request reprint Suppression of transcription polarity in the Escherichia coli haemolysin operon by a short upstream element shared by polysaccharide and DNA transfer determinants
    J M Nieto
    Department of Pathology, University of Cambridge, UK
    Mol Microbiol 19:705-13. 1996
    ..We name it the ops element for operon polarity suppressor...
  31. ncbi request reprint Protein export and drug efflux through bacterial channel-tunnels
    C Andersen
    Cambridge University Department of Pathology, Tennis Court Road, CB2 1QP, Cambridge, UK
    Curr Opin Cell Biol 13:412-6. 2001
    ..TolC and its homologues thus provide large exit ducts for a wide range of substrates, including protein toxins and antibacterial drugs, that are engaged by specific recognition proteins in the cytosolic membrane...
  32. pmc Membrane interaction of Escherichia coli hemolysin: flotation and insertion-dependent labeling by phospholipid vesicles
    C Hyland
    Cambridge University Department of Pathology, Cambridge, CB2 1QP, United Kingdom
    J Bacteriol 183:5364-70. 2001
    ..Generation of five smaller peptides from the N-terminal region identified the principal determinant of lipid insertion as the hydrophobic sequence encompassing residues 177 to 411, which is conserved among hemolysin-related toxins...
  33. ncbi request reprint "I got some swords and you're dead!": violent fantasy, antisocial behavior, friendship, and moral sensibility in young children
    J Dunn
    Genetic and Developmental Psychiatry Research Centre, King s College London, UK
    Child Dev 72:491-505. 2001
    ..The usefulness of a focus on the content of children's pretend play-in particular, violent fantasy-as a window on children's preoccupations is considered...
  34. pmc Substrate complexes and domain organization of the Salmonella flagellar export chaperones FlgN and FliT
    J C Bennett
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Mol Microbiol 39:781-91. 2001
    ..In support of this view, the flgN mutation was specifically complemented by a hybrid chaperone comprising the N-terminal half of FliT and the C-terminal half of FlgN...
  35. ncbi request reprint Escherichia coli HlyT protein, a transcriptional activator of haemolysin synthesis and secretion, is encoded by the rfaH (sfrB) locus required for expression of sex factor and lipopolysaccharide genes
    M J Bailey
    Department of Pathology, University of Cambridge, UK
    Mol Microbiol 6:1003-12. 1992
    ..DNA sequencing of the hlyT locus identifies the HlyT/RfaH transcriptional activator as a protein of 162 amino acids (Mr 18325) which shows no identity to characterized transcription factors...
  36. ncbi request reprint Antisocial, angry, and unsympathetic: "hard-to-manage" preschoolers' peer problems and possible cognitive influences
    C Hughes
    Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 41:169-79. 2000
    ..However, given the relatively low power of the study, these findings require replication with a larger sample...
  37. ncbi request reprint Trick or treat?: uneven understanding of mind and emotion and executive dysfunction in "hard-to-manage" preschoolers
    C Hughes
    MRC Child and Adolescent Psychiatry Unit, Institute of Psychiatry, London, UK
    J Child Psychol Psychiatry 39:981-94. 1998
    ..Moreover, executive function was associated with performance on the theory of mind tasks for the hard-to-manage group alone, suggesting both direct and indirect links between executive dysfunction and disruptive behaviour...
  38. ncbi request reprint Infant vision screening predicts failures on motor and cognitive tests up to school age
    Janette Atkinson
    Visual Development Unit, Department of Psychology, University College London, London, UK
    Strabismus 10:187-98. 2002
    ..5 years. These effects are concentrated in visuocognitive and visuomotor domains rather than the linguistic domain...
  39. ncbi request reprint Streptavidin paramagnetic particles provide a choice of three affinity-based capture and magnetic concentration strategies for retroviral vectors
    C Hughes
    Guy's, King's, and St. Thomas' School of Medicine, Department of Molecular Medicine, The Rayne Institute, 123 Coldharbour Lane, London, SE5 9NU, United Kingdom
    Mol Ther 3:623-30. 2001
    ..Magnetic field-dependent localization such as this may enable the in vivo administration of formulations that concentrate retroviral infection to the required target tissues and organs...
  40. ncbi request reprint Understanding mind and emotion: longitudinal associations with mental-state talk between young friends
    C Hughes
    Medical Research Council Child and Adolescent Psychiatry Unit, Institute of Psychiatry, London, England
    Dev Psychol 34:1026-37. 1998
    ..Although there were no gender differences in children's task performances, girls showed more frequent and more developed mental-state talk than boys...