R F Howard

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Current status of pain management in children
    Richard F Howard
    Anaesthesia and Pain Management, Children Nationwide Pain Research Centre, and Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London, England
    JAMA 290:2464-9. 2003
  2. ncbi request reprint Inflammatory pain and hypersensitivity are selectively reversed by epidural bupivacaine and are developmentally regulated
    R F Howard
    Department of Anesthesia, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, London, United Kingdom
    Anesthesiology 95:421-7. 2001
  3. doi request reprint Nurse-controlled analgesia (NCA) following major surgery in 10,000 patients in a children's hospital
    Richard F Howard
    Department of Anaesthesia and Pain Management, Great Ormond Street Hospital for Children, London, UK
    Paediatr Anaesth 20:126-34. 2010
  4. ncbi request reprint The ontogeny of neuropathic pain: postnatal onset of mechanical allodynia in rat spared nerve injury (SNI) and chronic constriction injury (CCI) models
    Richard F Howard
    Department of Anaesthesia, Level 4, Old Building, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, London WC1N 2JH, UK
    Pain 115:382-9. 2005
  5. ncbi request reprint The efficacy of morphine and Entonox analgesia during chest drain removal in children
    Elizabeth Bruce
    Pain Control Service, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Paediatr Anaesth 16:302-8. 2006
  6. ncbi request reprint Chest drain removal pain and its management: a literature review
    Elizabeth A Bruce
    Great Ormond Street Hospital for Children NHS Trust, London, UK
    J Clin Nurs 15:145-54. 2006
  7. ncbi request reprint Developmental age influences the effect of epidural dexmedetomidine on inflammatory hyperalgesia in rat pups
    Suellen M Walker
    University of Sydney Pain Management and Research Centre, Royal North Shore Hospital, St Leonard s, New South Wales, Australia
    Anesthesiology 102:1226-34. 2005
  8. doi request reprint The addition of ketamine to a morphine nurse- or patient-controlled analgesia infusion (PCA/NCA) increases analgesic efficacy in children with mucositis pain
    Paul J James
    Evelina Children s Hospital, London, UK
    Paediatr Anaesth 20:805-11. 2010
  9. ncbi request reprint Developmental regulation of codeine analgesia in the rat
    D Glyn Williams
    Portex Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, University College London, United Kingdom
    Anesthesiology 100:92-7. 2004
  10. ncbi request reprint Clinical signs of infection during continuous postoperative epidural analgesia in children: the value of catheter tip culture
    N Seth
    Department of Anaesthesia, Guys and St Thomas s Hospitals NHS Trust, London, UK
    Paediatr Anaesth 14:996-1000. 2004

Detail Information

Publications14

  1. ncbi request reprint Current status of pain management in children
    Richard F Howard
    Anaesthesia and Pain Management, Children Nationwide Pain Research Centre, and Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust, London, England
    JAMA 290:2464-9. 2003
    ..The assessment and treatment of this pain and its functional consequences present a considerable unmet challenge. There is a pressing need for further research and clinical development in the management of pain in children...
  2. ncbi request reprint Inflammatory pain and hypersensitivity are selectively reversed by epidural bupivacaine and are developmentally regulated
    R F Howard
    Department of Anesthesia, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, London, United Kingdom
    Anesthesiology 95:421-7. 2001
    ..The aim of this work was to investigate whether such low doses applied epidurally selectively reduce nociceptive responses in vivo and to investigate the influence of postnatal development on such local anesthetic actions...
  3. doi request reprint Nurse-controlled analgesia (NCA) following major surgery in 10,000 patients in a children's hospital
    Richard F Howard
    Department of Anaesthesia and Pain Management, Great Ormond Street Hospital for Children, London, UK
    Paediatr Anaesth 20:126-34. 2010
    ....
  4. ncbi request reprint The ontogeny of neuropathic pain: postnatal onset of mechanical allodynia in rat spared nerve injury (SNI) and chronic constriction injury (CCI) models
    Richard F Howard
    Department of Anaesthesia, Level 4, Old Building, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, London WC1N 2JH, UK
    Pain 115:382-9. 2005
    ..The results are consistent with human neonatal responses to nerve injury; further study of underlying mechanisms are likely to yield important information about the pathogenesis and treatment of neuropathic pain...
  5. ncbi request reprint The efficacy of morphine and Entonox analgesia during chest drain removal in children
    Elizabeth Bruce
    Pain Control Service, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Paediatr Anaesth 16:302-8. 2006
    ..Morphine is commonly used for chest drain removal pain, although a few studies in adults suggest that inhalation agents may be effective for this procedure. Little is known about chest drain removal pain and its management in children...
  6. ncbi request reprint Chest drain removal pain and its management: a literature review
    Elizabeth A Bruce
    Great Ormond Street Hospital for Children NHS Trust, London, UK
    J Clin Nurs 15:145-54. 2006
    ..The findings of descriptive and non-pharmacological intervention studies were summarized and studies of analgesic efficacy were critiqued in depth...
  7. ncbi request reprint Developmental age influences the effect of epidural dexmedetomidine on inflammatory hyperalgesia in rat pups
    Suellen M Walker
    University of Sydney Pain Management and Research Centre, Royal North Shore Hospital, St Leonard s, New South Wales, Australia
    Anesthesiology 102:1226-34. 2005
    ..The aim of this study was to determine the effect of epidural dexmedetomidine on sensory processing, reversal of inflammatory hyperalgesia, and sedation during early development in rats...
  8. doi request reprint The addition of ketamine to a morphine nurse- or patient-controlled analgesia infusion (PCA/NCA) increases analgesic efficacy in children with mucositis pain
    Paul J James
    Evelina Children s Hospital, London, UK
    Paediatr Anaesth 20:805-11. 2010
    ..To assess the efficacy of adding ketamine to morphine nurse- or patient-controlled analgesia (NCA/PCA) infusions in treating mucositis pain in children...
  9. ncbi request reprint Developmental regulation of codeine analgesia in the rat
    D Glyn Williams
    Portex Department of Anaesthesia, Great Ormond Street Hospital for Children NHS Trust and the Institute of Child Health, University College London, United Kingdom
    Anesthesiology 100:92-7. 2004
    ..Codeine is often given to infants and children. The aim of this study was to investigate the effects of developmental age on codeine analgesia in rats...
  10. ncbi request reprint Clinical signs of infection during continuous postoperative epidural analgesia in children: the value of catheter tip culture
    N Seth
    Department of Anaesthesia, Guys and St Thomas s Hospitals NHS Trust, London, UK
    Paediatr Anaesth 14:996-1000. 2004
    ..Infection arising from the use of epidural catheters for postoperative analgesia is a major source of anxiety...
  11. ncbi request reprint Epidural analgesia in children. A survey of current opinions and practices amongst UK paediatric anaesthetists
    D G Williams
    Great Ormond Street Hospital for Children, NHS Trust and Children Nationwide Pain Research Centre, London Portex Department of Anaesthesia, Institute of Child Health, London, UK
    Paediatr Anaesth 13:769-76. 2003
    ..In order to investigate the current practice of paediatric epidural analgesia in the UK paediatric anaesthetists and paediatric pain management teams were surveyed...
  12. pmc Population pharmacokinetics of oral diclofenac for acute pain in children
    Joseph F Standing
    Great Ormond Street Hospital for Children, London, UK
    Br J Clin Pharmacol 66:846-53. 2008
    ..To develop a population pharmacokinetic model for a new diclofenac suspension (50 mg 5 ml(-1)) in adult volunteers and paediatric patients, and recommend a dose for acute pain in children...
  13. pmc Prospective observational study of adverse drug reactions to diclofenac in children
    Joseph F Standing
    Great Ormond Street Hospital for Children, School of Pharmacy, University of London, London, UK
    Br J Clin Pharmacol 68:243-51. 2009
    ..The aim of this study was to investigate the type of common (occurring in >1% of patients) adverse reactions caused by diclofenac when given to children for acute pain...
  14. ncbi request reprint The functional expression of mu opioid receptors on sensory neurons is developmentally regulated; morphine analgesia is less selective in the neonate
    Reema Nandi
    Department of Anatomy and Developmental Biology, University College London, Gower Street, London WC1E6BT, UK
    Pain 111:38-50. 2004
    ..These results have important clinical implications for the use of morphine in neonates and provide a possible explanation for the differences in morphine requirements observed in the youngest patients...