Patrick J Horner
Affiliation: University of Bristol
- Quantitative analysis of epithelial cells in urine from men with and without urethritis: implications for studying epithelial: pathogen interactions in vivoRebecca Wiggins
Department of Medical Biochemistry and Immunology, Cardiff University, The Tenovus Building, Academic Avenue, Heath Park, Cardiff, UK
BMC Res Notes 2:139. 2009..These would provide novel opportunities for studying cellular interactions of C. trachomatis in male urethral infections, about which little is currently known...
- Testing for sexually transmitted infections in general practice: cross-sectional studyKatharine E Sadler
Research Department of Infection and Population Health, University College London, London, UK
BMC Public Health 10:667. 2010..We sought to explore the extent of testing for chlamydia and HIV in general practice and its relation to associated measures of sexual health in two contrasting geographical settings...
- Comparative performance of culture using swabs transported in Amies medium and the Aptima Combo 2 nucleic acid amplification test in detection of Neisseria gonorrhoeae from genital and extra-genital sites: a retrospective studyLindsey Harryman
Bristol Sexual Health Centre, University Hospitals NHS Foundation Trust, Bristol, UK
Sex Transm Infect 88:27-31. 2012..The authors investigated how symptoms and infection site influenced test sensitivity...
- Association of Mycoplasma genitalium with balanoposthitis in men with non-gonococcal urethritisPatrick J Horner
Department of Social Medicine, School of Social and Community Medicine, University of Bristol, 39 Whatley Road, Bristol BS8 2PS, UK
Sex Transm Infect 87:38-40. 2011..To determine whether Mycoplasma genitalium is associated with balanitis and/or posthitis in a previous study of the role of M genitalium in men with acute non-gonococcal urethritis (NGU)...
- Is there a role for leucocyte esterase testing in non-invasive screening using nucleic acid amplification tests of asymptomatic men?Patrick J Horner
Milne Sexual Health Centre, Bristol Royal Infirmary, Lower Maudlin Street, Bristol BS2 8HW
Int J STD AIDS 18:73-4. 2007....
- The case for further treatment studies of uncomplicated genital Chlamydia trachomatis infectionP Horner
The Milne Centre for Sexual Health, Bristol Royal, Infirmary, Lower Maudlin Street, Bristol BS2 8HW, UK
Sex Transm Infect 82:340-3. 2006..Given the imminent role out of the National Chlamydia Screening Programme and the consequences of persistent chlamydial infection in women this hypothesis urgently merits further investigation...
- Should we still be testing for asymptomatic non-specific urethritis in departments of genitourinary medicine?P J Horner
Milne Sexual Health Centre, Bristol Royal Infirmary, Lower Maudlin Street, Bristol BS2 8HW, UK
Int J STD AIDS 16:273-7. 2005..This review article summarizes the available evidence and argues that research is urgently needed in order to properly evaluate the cost-effectiveness of detecting urethritis in asymptomatic men...
- Enhanced enzyme immunoassay with negative-gray-zone testing compared to a single nucleic Acid amplification technique for community-based chlamydial screening of menPaddy Horner
The Milne Centre, United Bristol Healthcare Trust, Bristol BS2 8HW, United Kingdom
J Clin Microbiol 43:2065-9. 2005..In addition, positive nucleic acid amplification test results should be confirmed and an inhibition control should be used...
- Quantifying leukocytes in first catch urine provides new insights into our understanding of symptomatic and asymptomatic urethritisRebecca C Wiggins
Department of Clinical Sciences at South Bristol, University of Bristol, Bristol BS2 8AE, UK
Int J STD AIDS 17:289-95. 2006..This would explain why men with asymptomatic urethritis are less likely to have a sexually transmitted infection detected than those with discharge and/or dysuria...
- Mycoplasma genitalium is associated with symptomatic urethritisA Leung
Department of Genitourinary Medicine, Bristol Royal Infirmary, Bristol BS2 8AS, UK
Int J STD AIDS 17:285-8. 2006..genitalium detected (OR 2.61, 95% CI [1.09-6.25], P = 0.032). We found no association with younger age or a recent change of sexual partner. In conclusion, M. genitalium is associated with symptomatic urethritis...
- The chlamydia screening studies: rationale and designN Low
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Sex Transm Infect 80:342-8. 2004..Screening has been recommended to reduce the prevalence and morbidity associated with genital chlamydia infection in the United Kingdom...
- A novel polymerase chain reaction assay to detect Mycoplasma genitaliumK Eastick
Public Health Laboratory, Level 8, Bristol Royal Infirmary, Maudlin Street, Bristol BS2 8HW, UK
Mol Pathol 56:25-8. 2003..To design and validate a polymerase chain reaction (PCR) assay targeting the 16S rRNA gene of Mycoplasma genitalium...