Andrew L Hopkins

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. ncbi request reprint Network pharmacology
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, United Kingdom
    Nat Biotechnol 25:1110-1. 2007
  2. doi request reprint Network pharmacology: the next paradigm in drug discovery
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Science, University of Dundee, Dundee, UK
    Nat Chem Biol 4:682-90. 2008
  3. pmc Rapid analysis of pharmacology for infectious diseases
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, UK
    Curr Top Med Chem 11:1292-300. 2011
  4. pmc Automated design of ligands to polypharmacological profiles
    Jérémy Besnard
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    Nature 492:215-20. 2012
  5. ncbi request reprint Structural bioinformatics in drug discovery
    Eric B Fauman
    Discovery Research Informatics, Ann Arbor, MI, USA
    Methods Biochem Anal 44:477-97. 2003
  6. ncbi request reprint Global mapping of pharmacological space
    Gaia V Paolini
    The Department of Knowledge Discovery, Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Nat Biotechnol 24:805-15. 2006

Collaborators

  • Vincent Setola
  • Ian H Gilbert
  • John P Overington
  • Jérémy Besnard
  • Gaia V Paolini
  • Eric B Fauman
  • Xi Ping Huang
  • Nabil G Seidah
  • Lauren A Webster
  • Kevin D Read
  • Ramona M Rodriguiz
  • Bryan L Roth
  • William C Wetsel
  • Keren Abecassis
  • G Richard Bickerton
  • Maria F Sassano
  • Gian Filippo Ruda
  • Laste Stojanovski
  • Annik Prat
  • Antony I Shin
  • Suzanne Norval
  • Daniel B Constam
  • Frederick R C Simeons
  • Richard H B Shapland
  • Jonathan S Mason
  • Willem P van Hoorn
  • Colin R Groom

Detail Information

Publications6

  1. ncbi request reprint Network pharmacology
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, United Kingdom
    Nat Biotechnol 25:1110-1. 2007
  2. doi request reprint Network pharmacology: the next paradigm in drug discovery
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Science, University of Dundee, Dundee, UK
    Nat Chem Biol 4:682-90. 2008
    ..Advances in these areas are creating the foundation of the next paradigm in drug discovery: network pharmacology...
  3. pmc Rapid analysis of pharmacology for infectious diseases
    Andrew L Hopkins
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, UK
    Curr Top Med Chem 11:1292-300. 2011
    ....
  4. pmc Automated design of ligands to polypharmacological profiles
    Jérémy Besnard
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK
    Nature 492:215-20. 2012
    ..We also demonstrate target engagement in vivo. The approach can be a useful source of drug leads when multi-target profiles are required to achieve either selectivity over other drug targets or a desired polypharmacology...
  5. ncbi request reprint Structural bioinformatics in drug discovery
    Eric B Fauman
    Discovery Research Informatics, Ann Arbor, MI, USA
    Methods Biochem Anal 44:477-97. 2003
  6. ncbi request reprint Global mapping of pharmacological space
    Gaia V Paolini
    The Department of Knowledge Discovery, Pfizer Global Research and Development, Sandwich, Kent CT13 9NJ, UK
    Nat Biotechnol 24:805-15. 2006
    ..The relationships between proteins, chemical structures and drug-like properties provide a framework for developing a probabilistic approach to drug discovery that can be exploited to increase research productivity...