Richard FD Hobbs

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. doi request reprint Barriers to cardiovascular disease risk scoring and primary prevention in Europe
    F D R Hobbs
    Primary Care Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    QJM 103:727-39. 2010
  2. pmc Research output on primary care in Australia, Canada, Germany, the Netherlands, the United Kingdom, and the United States: bibliometric analysis
    Julie Glanville
    York Health Economics Consortium, University of York
    BMJ 342:d1028. 2011
  3. pmc Heart failure guidelines and prescribing in primary care across Europe
    Heidrun B Sturm
    Department of Clinical Pharmacology, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    BMC Health Serv Res 5:57. 2005
  4. pmc SMART: self-management of anticoagulation, a randomised trial [ISRCTN19313375]
    Deborah McCahon
    BMC Fam Pract 4:11. 2003
  5. pmc A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s: (SAFE) [ISRCTN19633732]
    Dawn Swancutt
    Department of Primary Care and General Practice, The University of Birmingham, UK
    BMC Cardiovasc Disord 4:12. 2004
  6. pmc Protocol for a randomised controlled trial of telemonitoring and self-management in the control of hypertension: telemonitoring and self-management in hypertension. [ISRCTN17585681]
    Richard J McManus
    Primary Care Clinical Sciences, Primary Care and Clinical Sciences Building, University of Birmingham, Birmingham, UK
    BMC Cardiovasc Disord 9:6. 2009
  7. pmc Protocol for Birmingham Atrial Fibrillation Treatment of the Aged study (BAFTA): a randomised controlled trial of warfarin versus aspirin for stroke prevention in the management of atrial fibrillation in an elderly primary care population [ISRCTN89345269]
    Jonathan W F Mant
    Department of Primary Care and General Practice, University of Birmingham, UK
    BMC Cardiovasc Disord 3:9. 2003
  8. pmc Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care
    Kate Fletcher
    Primary Care Clinical Sciences, Clinical Sciences Building University of Birmingham, Edgbaston, Birmingham, UK
    BMC Cardiovasc Disord 10:37. 2010
  9. pmc Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme
    Sue Wilson
    Primary Care Clinical Sciences, The University of Birmingham, Birmingham, UK
    BMC Cancer 9:36. 2009
  10. pmc Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population
    Sue Wilson
    Department of Primary Care and General Practice, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    BMC Cancer 6:258. 2006

Detail Information

Publications84

  1. doi request reprint Barriers to cardiovascular disease risk scoring and primary prevention in Europe
    F D R Hobbs
    Primary Care Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    QJM 103:727-39. 2010
    ..A thorough, easy-to-use, and standardized tool for risk estimation would allow for improvements in the primary prevention of CVD...
  2. pmc Research output on primary care in Australia, Canada, Germany, the Netherlands, the United Kingdom, and the United States: bibliometric analysis
    Julie Glanville
    York Health Economics Consortium, University of York
    BMJ 342:d1028. 2011
    ..To compare the volume and quality of original research in primary care published by researchers from primary care in the United Kingdom against five countries with well established academic primary care...
  3. pmc Heart failure guidelines and prescribing in primary care across Europe
    Heidrun B Sturm
    Department of Clinical Pharmacology, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, The Netherlands
    BMC Health Serv Res 5:57. 2005
    ..National guideline recommendations might be a relevant factor. This study, therefore, explored variation of heart failure guideline recommendations in Europe...
  4. pmc SMART: self-management of anticoagulation, a randomised trial [ISRCTN19313375]
    Deborah McCahon
    BMC Fam Pract 4:11. 2003
    ..Patient self-management is a logical progression from the primary care model. This study will be the first to randomise non-selected patients in primary care, to either self-management or standard care...
  5. pmc A randomised controlled trial and cost effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in the over 65s: (SAFE) [ISRCTN19633732]
    Dawn Swancutt
    Department of Primary Care and General Practice, The University of Birmingham, UK
    BMC Cardiovasc Disord 4:12. 2004
    ..The value of clinical assessment and echocardiography as additional methods of risk stratification for thromboembolic disease in patients with AF were also evaluated...
  6. pmc Protocol for a randomised controlled trial of telemonitoring and self-management in the control of hypertension: telemonitoring and self-management in hypertension. [ISRCTN17585681]
    Richard J McManus
    Primary Care Clinical Sciences, Primary Care and Clinical Sciences Building, University of Birmingham, Birmingham, UK
    BMC Cardiovasc Disord 9:6. 2009
    ..Self-management of hypertension is an under researched area in which potential benefits for both patients and professionals are great...
  7. pmc Protocol for Birmingham Atrial Fibrillation Treatment of the Aged study (BAFTA): a randomised controlled trial of warfarin versus aspirin for stroke prevention in the management of atrial fibrillation in an elderly primary care population [ISRCTN89345269]
    Jonathan W F Mant
    Department of Primary Care and General Practice, University of Birmingham, UK
    BMC Cardiovasc Disord 3:9. 2003
    ..The Birmingham Atrial Fibrillation Treatment of the Aged (BAFTA) study will provide evidence of the risks and benefits of warfarin versus aspirin for the prevention of stroke for older people with AF in a primary care setting...
  8. pmc Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care
    Kate Fletcher
    Primary Care Clinical Sciences, Clinical Sciences Building University of Birmingham, Edgbaston, Birmingham, UK
    BMC Cardiovasc Disord 10:37. 2010
    ..PAST BP will determine whether more intensive BP targets can be achieved in a primary care setting, and whether more intensive therapy is associated with adverse effects on quality of life...
  9. pmc Establishing the added benefit of measuring MMP9 in FOB positive patients as a part of the Wolverhampton colorectal cancer screening programme
    Sue Wilson
    Primary Care Clinical Sciences, The University of Birmingham, Birmingham, UK
    BMC Cancer 9:36. 2009
    ..MMP9 has potential for detecting those at risk of having colorectal cancer. The aim of this study is to assess whether MMP9 estimation enhances the predictive value of a positive FOBt...
  10. pmc Evaluation of the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population
    Sue Wilson
    Department of Primary Care and General Practice, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    BMC Cancer 6:258. 2006
    ..Serum MMP-9 is potentially an accurate, low risk and cost-effective population screening tool. This study aims to evaluate the accuracy of serum MMP-9 as a test for colorectal cancer in a primary care population...
  11. pmc A prospective study to assess the value of MMP-9 in improving the appropriateness of urgent referrals for colorectal cancer
    Angela V Ryan
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT, UK
    BMC Cancer 6:251. 2006
    ..This study aims to find out whether measuring MMP-9 levels could improve the appropriateness of urgent referrals for patients with bowel symptoms...
  12. pmc Cardiovascular disease: different strategies for primary and secondary prevention?
    F D R Hobbs
    Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK
    Heart 90:1217-23. 2004
  13. pmc Doxazosin versus bendrofluazide: a comparison of the metabolic effects in British South Asians with hypertension
    Fd Richard Hobbs
    Department of Primary Care and General Practice, University of Birmingham, Birmingham
    Br J Gen Pract 55:437-43. 2005
    ..Doxazosin, a selective alpha(1)-adrenergic blocker, in addition to lowering blood pressure, has been shown to have positive effects on glucose metabolism and lipid profiles in patients with hypertension...
  14. ncbi request reprint The diagnosis of heart failure in European primary care: The IMPROVEMENT Programme survey of perception and practice
    F D Richard Hobbs
    Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Eur J Heart Fail 7:768-79. 2005
    ..To examine European primary care physicians (PCPs) views on diagnosis of heart failure and compare perceptions with actual practice...
  15. ncbi request reprint Achievement of English National Service Framework lipid-lowering goals: pooled data from recent comparative treatment trials of statins at starting doses
    F D R Hobbs
    The Medical School, University of Birmingham, Birmingham, UK
    Int J Clin Pract 59:1171-7. 2005
    ..49% on simvaststin and 24% on pravastatin. In summary, there are considerable and clinically significant variations in the achievement of lipid goals between common starting doses of statins in hypercholesterolaemic patients...
  16. ncbi request reprint Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an international, open-label program to assess the effectiveness of a single pill (amlodipine/atorv
    F D Richard Hobbs
    Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, UK
    Int J Cardiol 110:242-50. 2006
    ..The JEWEL study program will investigate the use of single-pill amlodipine/atorvastatin as a strategy to improve management of these patients...
  17. ncbi request reprint Effective management of dyslipidaemia among patients with cardiovascular risk: updated recommendations on identification and follow-up
    Richard Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, UK
    Eur J Gen Pract 11:68-75. 2005
    ..This clinical review highlights the problems in current CHD risk management and summarises the updated evidence base within clinical recommendations to effectively manage at-risk patients...
  18. ncbi request reprint Type-2 diabetes mellitus related cardiovascular risk: new options for interventions to reduce risk and treatment goals
    F D Richard Hobbs
    University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Atheroscler Suppl 7:29-32. 2006
    ....
  19. doi request reprint International open-label studies to assess the efficacy and safety of single-pill amlodipine/atorvastatin in attaining blood pressure and lipid targets recommended by country-specific guidelines: the JEWEL programme
    Frederick D Richard Hobbs
    University of Birmingham, Edgbaston, Birmingham, UK
    Eur J Cardiovasc Prev Rehabil 16:472-80. 2009
    ..We evaluated the clinical utility of this single pill to help patients across Europe and Canada achieve country-specific targets for blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C)...
  20. ncbi request reprint Prognosis of all-cause heart failure and borderline left ventricular systolic dysfunction: 5 year mortality follow-up of the Echocardiographic Heart of England Screening Study (ECHOES)
    F D Richard Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK
    Eur Heart J 28:1128-34. 2007
    ..However, for a number of reasons, neither type of study have, to date, provided generalizable data on HF mortality. Furthermore, data on the prognosis of borderline left ventricular systolic dysfunction (LVSD) are even more limited...
  21. pmc Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? The single pill of amlodipine/atorvastatin
    F D Richard Hobbs
    University of Birmingham, Edgbaston, Birmingham, UK
    Vasc Health Risk Manag 3:711-9. 2007
    ....
  22. ncbi request reprint The From The Heart study: a global survey of patient understanding of cholesterol management and cardiovascular risk, and physician-patient communication
    F D Richard Hobbs
    Primary Care Clinical Sciences Building, University of Birmingham, Birmingham, UK
    Curr Med Res Opin 24:1267-78. 2008
    ..However, little is known of patient perceptions about CVD risk...
  23. pmc Should we ditch impact factors?
    Richard Hobbs
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 334:569. 2007
  24. pmc Reliability of N-terminal proBNP assay in diagnosis of left ventricular systolic dysfunction within representative and high risk populations
    F D R Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK
    Heart 90:866-70. 2004
    ..To determine the performance of a new NT-proBNP assay in comparison with brain natriuretic peptide (BNP) in identifying left ventricular systolic dysfunction (LVSD) in randomly selected community populations...
  25. ncbi request reprint Cardiovascular risk management in primary care
    F D Richard Hobbs
    Primary Care Clinical Sciences Building, School of Medicine, University of Birmingham, Birmingham, UK
    Diabetes Obes Metab 4:362-7. 2002
  26. ncbi request reprint Cardiovascular disease and lipids. Issues and evidence for the management of dyslipidaemia in primary care
    F D Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham, B15 2TT, United Kingdom
    Eur J Gen Pract 9:16-24. 2003
    ..In summary, the application of the enormous evidence-base for interventions in cardiovascular disease, especially over the treatment of elevated cholesterol, pose a huge challenge to primary and secondary care in most healthcare systems...
  27. ncbi request reprint Acceptance of guideline recommendations and perceived implementation of coronary heart disease prevention among primary care physicians in five European countries: the Reassessing European Attitudes about Cardiovascular Treatment (REACT) survey
    F D Richard Hobbs
    Division of Primary Care, Public and Occupational Health, Department of Primary Care and General Practice, University of Birmingham, Edgbaston, UK
    Fam Pract 19:596-604. 2002
    ..The REACT survey was designed to assess the views, and perceived implementation, of CHD and lipid treatment guidelines among primary care physicians...
  28. pmc Reliability of N-terminal pro-brain natriuretic peptide assay in diagnosis of heart failure: cohort study in representative and high risk community populations
    F D R Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT
    BMJ 324:1498. 2002
    ..To investigate the performance of a novel assay for N-terminal pro-brain natriuretic peptide (NT-proBNP) in diagnosing heart failure in various randomly selected general and high risk community populations...
  29. pmc Management of heart failure: evidence versus practice. Does current prescribing provide optimal treatment for heart failure patients?
    F D Hobbs
    Department of Primary Care and General Practice, University of Birmingham Medical School
    Br J Gen Pract 50:735-42. 2000
    ..Current evidence suggests that in North America and Europe today primary care physicians do underperform in their management of patients with heart failure, often owing to factors outside of their immediate control...
  30. pmc Primary prevention of cardiovascular disease: managing hypertension and hyperlipidaemia
    F D R Hobbs
    Primary Care and General Practice, Primary Care Clinical Sciences Building, School of Medicine, University of Birmingham, Birmingham B15 2TT, UK
    Heart 90:iv22-5. 2004
    ..There is a need to structure care to identify individuals who are at risk. Current targets are explicit and achievable for both hypertension and lipids. Effective treatment is likely to require multiple drug treatment...
  31. doi request reprint Telemonitoring and self-management in the control of hypertension (TASMINH2): a randomised controlled trial
    Richard J McManus
    Primary Care Clinical Sciences, University of Birmingham and National Institute for Health Research NIHR National School for Primary Care Research, Birmingham, UK
    Lancet 376:163-72. 2010
    ..This study assessed whether self-management by people with poorly controlled hypertension resulted in better blood pressure control compared with usual care...
  32. pmc Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: cluster randomised controlled trial
    David A Fitzmaurice
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 335:383. 2007
    ..To assess whether screening improves the detection of atrial fibrillation (cluster randomisation) and to compare systematic and opportunistic screening...
  33. ncbi request reprint A cross-sectional study of hypertension in an elderly population (75 years and over) with atrial fibrillation: secondary analysis of data from the Birmingham Atrial Fibrillation in the Aged (BAFTA) randomised controlled trial
    Victoria Hurley
    Department of Primary Care and General Practice, The University of Birmingham, Edgbaston, Birmingham B15 2TT, England, UK
    Int J Cardiol 117:152-6. 2007
    ..Little information is available regarding the epidemiology of hypertension in elderly patients with atrial fibrillation...
  34. ncbi request reprint Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial
    Jonathan Mant
    Primary Care Clinical Sciences, University of Birmingham, Birmingham, UK
    Lancet 370:493-503. 2007
    ..We assessed whether warfarin reduced risk of major stroke, arterial embolism, or other intracranial haemorrhage compared with aspirin in elderly patients...
  35. doi request reprint Cost effectiveness of warfarin versus aspirin in patients older than 75 years with atrial fibrillation
    Sue Jowett
    Health Economics Unit, Public Health Building, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Stroke 42:1717-21. 2011
    ..Although the benefits of reduced stroke risk outweigh the risks of bleeding, the cost effectiveness of warfarin in this patient population has not yet been established...
  36. ncbi request reprint Reducing cardiovascular risk in diabetes: beyond glycemic and blood pressure control
    F D Richard Hobbs
    Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, UK
    Int J Cardiol 110:137-45. 2006
    ....
  37. pmc Accuracy of diagnosing atrial fibrillation on electrocardiogram by primary care practitioners and interpretative diagnostic software: analysis of data from screening for atrial fibrillation in the elderly (SAFE) trial
    Jonathan Mant
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 335:380. 2007
    ..To assess the accuracy of general practitioners, practice nurses, and interpretative software in the use of different types of electrocardiogram to diagnose atrial fibrillation...
  38. ncbi request reprint "I" and "we": a concordancing analysis of how doctors and patients use first person pronouns in primary care consultations
    John R Skelton
    Department of Primary Care and General Practice, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Fam Pract 19:484-8. 2002
    ..It is widely accepted that "partnership" with patients is desirable, and that patients should be enabled to participate in decisions, but it is not clear to what extent doctor-patient interactions represent partnership in action...
  39. ncbi request reprint An analysis of factors that predict patient consent to take part in a randomized controlled trial
    Kate Fletcher
    Department of Primary Care and General Practice, The University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Fam Pract 24:388-94. 2007
    ..Recruitment targets of patients to multi-centre primary care-based randomized controlled trials (RCT) are often not met. A critical step in the pathway is whether an eligible patient will give consent...
  40. pmc Helicobacter pylori test and treat versus proton pump inhibitor in initial management of dyspepsia in primary care: multicentre randomised controlled trial (MRC-CUBE trial)
    Brendan C Delaney
    Primary Care Clinical Sciences, University of Birmingham, Birmingham B15 2TT
    BMJ 336:651-4. 2008
    ..To determine the cost effectiveness of Helicobacter pylori "test and treat" compared with empirical acid suppression in the initial management of patients with dyspepsia in primary care...
  41. doi request reprint Statins in heart failure: retrospective cohort study using routine primary care data
    Ronan P Ryan
    Primary Care Clinical Sciences, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK
    Ann Med 41:490-6. 2009
    ..This study aimed to assess the effect of a statin prescription prior to HF diagnosis on survival in an incident HF population...
  42. ncbi request reprint Is subclinical thyroid dysfunction in the elderly associated with depression or cognitive dysfunction?
    Lesley M Roberts
    Department of Primary Care and General Practice, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Ann Intern Med 145:573-81. 2006
    ..The clinical significance of this dysfunction, however, remains uncertain, and associations with cognitive impairment, depression, and anxiety are unconfirmed...
  43. ncbi request reprint Real-world trials to answer real-world questions
    Nick Freemantle
    University of Birmingham, Birmingham, UK
    Pharmacoeconomics 23:747-54. 2005
    ..As an example, a real-world trial currently underway that examines scenarios of introducing inhaled insulin into clinical practice is described...
  44. ncbi request reprint A randomised controlled trial and cost-effectiveness study of systematic screening (targeted and total population screening) versus routine practice for the detection of atrial fibrillation in people aged 65 and over. The SAFE study
    F D R Hobbs
    Department of Primary Care and General Practice, University of Birmingham, UK
    Health Technol Assess 9:iii-iv, ix-x, 1-74. 2005
    ..Also to evaluate the relative cost-effectiveness of different methods of recording and interpreting the electrocardiogram (ECG) within a screening programme...
  45. ncbi request reprint Thromboembolism
    David A Fitzmaurice
    The Medical School University of Birmingham, Birmingham, United Kingdom
    Am Fam Physician 69:132-4. 2004
  46. ncbi request reprint What is the place of beta-blockade in patients who have experienced a myocardial infarction with preserved left ventricular function? Evidence and (mis)interpretation
    Nick Freemantle
    Department of Primary Care and General Practice, School of Medicine, University of Birmingham, Edgbaston, UK
    Prog Cardiovasc Dis 44:243-50. 2002
    ..In this article we address a series of questions related to the important and continuing role of beta blockade after myocardial infarction...
  47. pmc Unmet need for diagnosis of heart failure: the view from primary care
    F D R Hobbs
    Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Heart 88:ii9-11. 2002
  48. ncbi request reprint Association between serum free thyroxine concentration and atrial fibrillation
    M D Gammage
    Department of Cardiovascular Medicine, University of Birmingham, Birmingham, England
    Arch Intern Med 167:928-34. 2007
    ..Our objective was to determine the relationship between thyroid function and presence of atrial fibrillation (AF) in older subjects...
  49. pmc Self management of oral anticoagulation: randomised trial
    D A Fitzmaurice
    Department of Primary Care, University of Birmingham, Birmingham
    BMJ 331:1057. 2005
    ..To determine the clinical effectiveness of self management compared with routine care in patients on long term oral anticoagulants...
  50. ncbi request reprint Major policy changes for primary care: potential lessons for the US New Model of family medicine from the quality and outcomes framework in the United Kingdom
    Helen Lester
    Department of Primary Care, University of Birmingham, UK
    Fam Med 39:96-102. 2007
    ....
  51. pmc Prevalence of left ventricular systolic dysfunction and heart failure in high risk patients: community based epidemiological study
    R C Davis
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT, UK
    BMJ 325:1156. 2002
    ..To determine the prevalence of left ventricular systolic dysfunction, and of heart failure due to different causes, in patients with risk factors for these conditions...
  52. doi request reprint A randomized controlled trial of the effect of thyroxine replacement on cognitive function in community-living elderly subjects with subclinical hypothyroidism: the Birmingham Elderly Thyroid study
    J Parle
    School of Health and Population Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B152TT, United Kingdom
    J Clin Endocrinol Metab 95:3623-32. 2010
    ..Subclinical hypothyroidism (SCH) and cognitive dysfunction are both common in the elderly and have been linked. It is important to determine whether T4 replacement therapy in SCH confers cognitive benefit...
  53. ncbi request reprint Rhythm control agents and adverse events in patients with atrial fibrillation
    C J Taylor
    Primary Care Clinical Sciences, School of Health and Population Sciences, University of Birmingham, Birmingham, UK
    Int J Clin Pract 64:1069-75. 2010
    ..Controversy remains about the best treatment strategy between rate and rhythm control (in addition to adequate thromboprophylaxis). Rhythm control agents are associated with clinically important adverse events...
  54. pmc Targets and self monitoring in hypertension: randomised controlled trial and cost effectiveness analysis
    R J McManus
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 331:493. 2005
    ....
  55. pmc A randomised controlled trial of patient self management of oral anticoagulation treatment compared with primary care management
    D A Fitzmaurice
    Department of Primary Care and General Practice, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    J Clin Pathol 55:845-9. 2002
    ..Patient self management for oral anticoagulation is a model new to the UK. This randomised trial was the first to compare routine primary care management of oral anticoagulation with patient self management...
  56. pmc Comparison of estimates and calculations of risk of coronary heart disease by doctors and nurses using different calculation tools in general practice: cross sectional study
    R J McManus
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 324:459-64. 2002
    ..To assess the effect of using different risk calculation tools on how general practitioners and practice nurses evaluate the risk of coronary heart disease with clinical data routinely available in patients' records...
  57. doi request reprint Impact of study design on recruitment of patients to a primary care trial: an observational time series analysis of the Birmingham Atrial Fibrillation Treatment of the Aged (BAFTA) study
    K Fletcher
    Department of Primary Care and General Practice, Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, UK
    Fam Pract 27:691-7. 2010
    ..recruitment targets to randomized controlled trials (RCTs) are often not met. Many interventions are used to improve recruitment but there is little empirical evidence on whether these approaches work...
  58. doi request reprint Anticoagulant management in patients with atrial fibrillation
    David A Fitzmaurice
    University of Birmingham, Birmingham, United Kingdom
    Semin Thromb Hemost 35:543-7. 2009
    ..0 to 3.0 (target: 2.5). To have a public health impact, patients with AF need efficient and correct identification, with appropriate treatment directed at those patients at most risk from the condition...
  59. pmc Does changing from mercury to electronic blood pressure measurement influence recorded blood pressure? An observational study
    Richard J McManus
    Department of Primary Care and General Practice, University of Birmingham, Edgbaston
    Br J Gen Pract 53:953-6. 2003
    ..No consistent change in mean blood pressure was apparent following their introduction, but there was a large and significant fall in terminal digit preference suggesting improved precision of recording...
  60. ncbi request reprint Availability of inhaled insulin promotes greater perceived acceptance of insulin therapy in patients with type 2 diabetes
    Nick Freemantle
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham Edgbaston, Birmingham B15 2TT UK
    Diabetes Care 28:427-8. 2005
  61. ncbi request reprint Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community-based cross-sectional survey
    Sue Wilson
    Department of Primary Care and General Practice, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom
    J Clin Endocrinol Metab 91:4809-16. 2006
    ..Population-based screening has been advocated for subclinical thyroid dysfunction in the elderly because the disorder is perceived to be common, and health benefits may be accrued by detection and treatment...
  62. ncbi request reprint Patient self-management of anticoagulation therapy: a trial-based cost-effectiveness analysis
    Sue Jowett
    Health Economics Facility, Health Services Management Centre, University of Birmingham, Birmingham, UK
    Br J Haematol 134:632-9. 2006
    ..However, PSM may have other benefits in relieving pressure on traditional clinic-based care, and the cost-effectiveness of this model of care for some subgroups of anticoagulation patients needs to be explored further...
  63. ncbi request reprint Left ventricular ejection fraction: are the revised cut-off points for defining systolic dysfunction sufficiently evidence based?
    G Mahadevan
    Department of Cardiovascular Medicine, University of Birmingham, 21 Metchley Park Road, Edgbaston, Birmingham B15 2PQ, UK
    Heart 94:426-8. 2008
  64. doi request reprint Ten-year prognosis of heart failure in the community: follow-up data from the Echocardiographic Heart of England Screening (ECHOES) study
    Clare J Taylor
    Primary Care Clinical Sciences, University of Birmingham, Edgbaston B15 2TT, UK
    Eur J Heart Fail 14:176-84. 2012
    ..This study investigates the 10-year survival in the ECHOES (Echocardiographic Heart of England Screening) study and examines factors associated with prognosis...
  65. pmc A concordance-based study of metaphoric expressions used by general practitioners and patients in consultation
    John R Skelton
    Department of Primary Care and General Practice, University of Birmingham, Edgbaston
    Br J Gen Pract 52:114-8. 2002
    ..Increasingly, it is suggested metaphoric expressions constrain the way we conceptualise the world, as well as being a means of achieving stylistic effect...
  66. ncbi request reprint A comparison of Bayesian and maximum likelihood methods to determine the performance of a point of care test for Helicobacter pylori in the office setting
    Brendan C Delaney
    Department of Primary Care and General Practice, Medical School, University of Birmingham, Edgbaston, United Kingdom
    Med Decis Making 23:21-30. 2003
    ..This study aimed to compare the results of a Bayesian statistical analysis and a maximum likelihood method to evaluate the performance of a PCT for Helicobacter pylori in primary care...
  67. pmc Type 2 diabetes, thiazolidinediones, and cardiovascular risk
    Clare Taylor
    Primary Care Clinical Services, University of Birmingham, Birmingham
    Br J Gen Pract 59:520-4. 2009
    ..This article discusses the evidence behind these concerns and the most recent guidance on use of thiazolidinediones in clinical practice...
  68. pmc Coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and prevalence of infection in the United Kingdom general population: cross sectional study
    John Macleod
    Department of Primary Care and General Practice, University of Birmingham, Birmingham B15 2TT
    BMJ 330:940. 2005
    ..To measure the coverage and uptake of systematic postal screening for genital Chlamydia trachomatis and the prevalence of infection in the general population in the United Kingdom. To investigate factors associated with these measures...
  69. pmc Predictors of incident atrial fibrillation and influence of medications: a retrospective case-control study
    James A Hodgkinson
    Department of Primary Care Clinical Sciences, School of Health and Population Sciences, University of Birmingham, UK
    Br J Gen Pract 61:e353-61. 2011
    ..Atrial fibrillation (AF) is a common condition, associated with raised mortality and risk of major morbidity, and is predicted to increase due to an aging population...
  70. doi request reprint Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care
    J Mant
    Primary Care Clinical Sciences, University of Birmingham, UK
    Health Technol Assess 13:1-207, iii. 2009
    ....
  71. ncbi request reprint A systematic review of the evidence for rapid access chest pain clinics
    R J McManus
    Department of Primary Care and General Practice, University of Birmingham, UK
    Int J Clin Pract 56:29-33. 2002
    ..In conclusion, the evidence base for the introduction of rapid access chest pain clinics is poor. The introduction of these clinics should include a randomised prospective evaluation of their worth...
  72. ncbi request reprint Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care
    J Mant
    Department of Primary Care and General Practice, University of Birmingham, UK
    Health Technol Assess 8:iii, 1-158. 2004
    ....
  73. ncbi request reprint Impact of heart failure and left ventricular systolic dysfunction on quality of life: a cross-sectional study comparing common chronic cardiac and medical disorders and a representative adult population
    F D R Hobbs
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Birmingham B15 2TT, U K
    Eur Heart J 23:1867-76. 2002
    ..However, despite the high prevalence and malignant prognosis, few studies have reported the impact of heart failure and LVSD on overall quality of life and, more crucially, have not researched the elderly or those in the community...
  74. ncbi request reprint How representative of primary care are research active practices? Cross-sectional survey
    Richard J McManus
    Department of Primary Care and General Practice, Primary Care Clinical Sciences Building, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Fam Pract 25:56-62. 2008
    ..There has been a continued trend towards undertaking primary care-based research but the characteristics and generalizability of practices that participate in such research are not well known...
  75. ncbi request reprint Public awareness of heart failure in Europe: first results from SHAPE
    Willem J Remme
    Sticares Cardiovascular Research Foundation, PO Box 882, 3160 AB Rhoon, The Netherlands
    Eur Heart J 26:2413-21. 2005
    ..The extent of public awareness in Europe is not known...
  76. ncbi request reprint Thromboembolism
    David A Fitzmaurice
    The Medical School University of Birmingham, United Kingdom
    Am Fam Physician 66:475-7. 2002
  77. doi request reprint Awareness and perception of heart failure among European cardiologists, internists, geriatricians, and primary care physicians
    Willem J Remme
    Sticares Cardiovascular Research Foundation, PO Box 882, 3160 AB Rhoon, The Netherlands
    Eur Heart J 29:1739-52. 2008
    ..To assess awareness of heart failure (HF) management recommendations in Europe among cardiologists (C), internists and geriatricians (I/G), and primary care physicians (PCPs)...
  78. ncbi request reprint Chronic obstructive pulmonary disease, risk factors, and outcome trials: comparisons with cardiovascular disease
    Scott D Ramsey
    University of Washington and Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Proc Am Thorac Soc 3:635-40. 2006
    ..There is a need for large prospective trials in COPD, based on hard clinical outcomes such as death, which, together with physician and patient education, will help to drive improvements in clinical management...
  79. ncbi request reprint Practical recommendations for the use of ACE inhibitors, beta-blockers, aldosterone antagonists and angiotensin receptor blockers in heart failure: putting guidelines into practice
    John McMurray
    Department of Cardiology, Western Infirmary, Glasgow, G12 8QQ, UK
    Eur J Heart Fail 7:710-21. 2005
    ..These practical recommendations are meant to serve as a supplement to, rather than replacement of, existing HF guidelines...
  80. ncbi request reprint Lipid management in cardiovascular disease prevention guidelines: strategies and tactics for implementation
    Leif R Erhardt
    Department of Cardiology, Malmo University Hospital, Malmo, Sweden
    Atherosclerosis 196:532-41. 2008
    ..Include professional societies from different specialties in guideline development and implementation, to increase ownership and decrease fragmentation of guideline committees...
  81. ncbi request reprint Concordance with heart failure medications: what do patients think?
    F D Richard Hobbs
    Fam Pract 23:607-8. 2006
  82. ncbi request reprint A single-pill combination of amlodipine besylate and atorvastatin calcium (update)
    Roy Blank
    Southern Piedmont Primary Care, Presbyterian Hospital, Charlotte, North Carolina, USA
    Drugs Today (Barc) 43:157-77. 2007
    ..These potential benefits are associated with important implications because hypertensive patients with additional risk factors represent a large proportion of those at risk for cardiovascular events...
  83. pmc How should we rate research?
    F D Richard Hobbs
    BMJ 332:983-4. 2006
  84. ncbi request reprint The potential for CETP inhibition to reduce cardiovascular disease risk
    Benjamin Ansell
    Division of General Internal Medicine Health Services Research, University of California Los Angeles School of Medicine, Los Angeles, CA 90095, USA
    Curr Med Res Opin 22:2467-78. 2006
    ....