Research Topics
| Julia Hippisley-CoxSummaryAffiliation: University of Nottingham Country: UK Publications
| Collaborators
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Detail Information
Publications
Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch databaseJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham NG2 7RD
BMJ 340:c2197. 2010..To quantify the unintended effects of statins according to type, dose, and duration of use...- Identifying patients with suspected lung cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, UK
Br J Gen Pract 61:e715-23. 2011..The challenge is to help earlier diagnosis of lung cancer and hence improve prognosis... - Identifying patients with suspected gastro-oesophageal cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, UK
Br J Gen Pract 61:e707-14. 2011..Gastro-oesphageal is one of the most common cancers worldwide. Evidence suggested that increased awareness of symptoms and earlier diagnosis could help improve treatment options and improve survival... 
Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort studyJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham, UK
BMJ 344:e3427. 2012..To develop and validate an updated version of the QFracture algorithm for estimating the risk of a patient sustaining an osteoporotic fracture or hip fracture in a primary care population...- Identifying patients with suspected renal tract cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham
Br J Gen Pract 62:e251-60. 2012..Earlier diagnosis of renal tract cancer could help improve survival so better tools are needed to help this... - Identifying patients with suspected pancreatic cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, University of Nottingham
Br J Gen Pract 62:e38-45. 2012..Pancreatic cancer has the worst survival for any cancer and is often diagnosed late when the cancer is advanced. Chances of survival are more likely if patients can be diagnosed earlier... - Identifying patients with suspected colorectal cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, University of Nottingham
Br J Gen Pract 62:e29-37. 2012..Earlier diagnosis of colorectal cancer could help improve survival so better tools are needed to help this... - Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithmJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, Nottingham NG2 7RD, UK
BMJ 344:d8009. 2012..To derive and validate an algorithm to estimate the absolute risk of having ovarian cancer in women with and without symptoms... - Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysisJulia Hippisley-Cox
Institution 13th floor, Tower Building, University Park, Nottingham NG2 7RD
BMJ 330:1366. 2005.... - Effect of statins on the mortality of patients with ischaemic heart disease: population based cohort study with nested case-control analysisJ Hippisley-Cox
University of Nottingham, Nottingham, UK
Heart 92:752-8. 2006..To measure the effect of statins on mortality for community based patients with ischaemic heart disease and determine whether the likely benefits are similar for women, the elderly, and patients with diabetes... - Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysisJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, Nottingham NG2 7RD
BMJ 331:1310-6. 2005..To determine the risk of an adverse upper gastrointestinal event in patients taking different cyclo-oxygenase-2 inhibitors compared with non-selective non-steroidal anti-inflammatory drugs... - Sex inequalities in access to care for patients with diabetes in primary care: questionnaire surveyJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, Nottingham
Br J Gen Pract 56:342-8. 2006..Given the increased prevalence of diabetes, the healthcare needs and experiences of women with diabetes are increasing... 
QFLU: new influenza monitoring in UK primary care to support pandemic influenza planningJ Hippisley-Cox
University of Nottingham, Nottingham, United Kingdom
Euro Surveill 11:E060622.4. 2006- Inequalities in the primary care of patients with coronary heart disease and serious mental health problems: a cross-sectional studyJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, Nottingham, UK
Heart 93:1256-62. 2007.... - Derivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort studyJulia Hippisley-Cox
Tower Building, University Park, Nottingham NG2 7RD
BMJ 335:136. 2007..To derive a new cardiovascular disease risk score (QRISK) for the United Kingdom and to validate its performance against the established Framingham cardiovascular disease algorithm and a newly developed Scottish score (ASSIGN)... - Performance of the QRISK cardiovascular risk prediction algorithm in an independent UK sample of patients from general practice: a validation studyJ Hippisley-Cox
Division of Primary Care, 13th Floor, Tower Building, University Park, Nottingham NG2 7RD, UK
Heart 94:34-9. 2008..To assess the performance of the QRISK score for predicting cardiovascular disease (CVD) in an independent UK sample from general practice and compare with the Framingham score... - Risk of malignancy in patients with schizophrenia or bipolar disorder: nested case-control studyJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, 13th Floor Tower Bldg, University Park, Nottingham NG7 2RD, England
Arch Gen Psychiatry 64:1368-76. 2007..There is conflicting evidence on whether people with schizophrenia have a different risk of cancer from that of the general population... - Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2Julia Hippisley-Cox
Division of Primary Care, Tower Building, University Park, Nottingham NG2 7RD
BMJ 336:1475-82. 2008.... - Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScoreJulia Hippisley-Cox
Division of Primary Care, Tower Building, University Park, Nottingham NG2 7RD
BMJ 338:b880. 2009..To develop and validate a new diabetes risk algorithm (the QDScore) for estimating 10 year risk of acquiring diagnosed type 2 diabetes over a 10 year time period in an ethnically and socioeconomically diverse population... - Predicting the risk of chronic Kidney Disease in men and women in England and Wales: prospective derivation and external validation of the QKidney ScoresJulia Hippisley-Cox
Division of Primary Care, 13th Floor, Tower Building, University Park, Nottingham NG2 7RD, UK
BMC Fam Pract 11:49. 2010.... - Coronary heart disease prevention and age inequalities: the first year of the National Service Framework for CHDJulia Hippisley-Cox
Division of General Practice, Nottingham University, UK
Br J Gen Pract 55:369-75. 2005..The National Service Framework for Heart Disease sets national standards and defines service models for coronary heart disease (CHD). Little is known about the impact of this intervention on age inequalities... - Effect of combinations of drugs on all cause mortality in patients with ischaemic heart disease: nested case-control analysisJulia Hippisley-Cox
Division of Primary Care, School of Community Health Sciences, University Park, Nottingham NG2 7RD
BMJ 330:1059-63. 2005..To determine the effect of combinations of statins, aspirin, beta blockers, and angiotensin converting enzyme inhibitors in the secondary prevention of all cause mortality in patients with ischaemic heart disease... - Cross sectional survey of socioeconomic variations in severity and mechanism of childhood injuries in Trent 1992-7Julia Hippisley-Cox
Division of General Practice, Tower Building University Park, Nottingham NG7 2RD
BMJ 324:1132. 2002..To determine the relation between morbidity from injury and deprivation for different levels of injury severity and for different injury mechanisms for children aged 0-14 years... - The electronic patient record in primary care--regression or progression? A cross sectional studyJulia Hippisley-Cox
Division of General Practice, Nottingham University, Nottingham NG7 2RD
BMJ 326:1439-43. 2003..To determine whether paperless medical records contained less information than paper based medical records and whether that information was harder to retrieve... - Antidepressants as risk factor for ischaemic heart disease: case-control study in primary careJ Hippisley-Cox
Division of General Practice, University of Nottingham, Nottingham NG7 2RD
BMJ 323:666-9. 2001..To determine whether antidepressants are a risk factor for ischaemic heart disease and to compare the risk for different subgroups of antidepressants and individual antidepressants... - Cross sectional survey of effectiveness of lipid lowering drugs in reducing serum cholesterol concentration in patients in 17 general practicesJulia Hippisley-Cox
Division of General Practice, Nottingham University, Nottingham NG7 2RD
BMJ 326:689. 2003..To compare the effectiveness of lipid lowering drugs in lowering serum cholesterol concentrations... - Sex inequalities in ischaemic heart disease in general practice: cross sectional surveyJ Hippisley-Cox
Division of General Practice, Nottingham University, Nottingham NG7 2RD, UK
BMJ 322:832. 2001..To study differences in treatment for men and women with ischaemic heart disease by using standards defined in England's national service framework for coronary artery disease... - A case-control study on the effect of hormone replacement therapy on ischaemic heart diseaseJulia Hippisley-Cox
Division of General Practice, University of Nottingham, 13th Floor, Tower Building, University Park, Nottingham NG2 7RD
Br J Gen Pract 53:191-6. 2003..Since CHD is common in women--about half of all postmenopausal women will get it and about a third of these will die from it--the effect of HRT on CHD is of great public health importance... - Inequalities in access to coronary angiography and revascularisation: the association of deprivation and location of primary care servicesJ Hippisley-Cox
Division of General Practice, Medical School, Queen s Medical Centre, Nottingham
Br J Gen Pract 50:449-54. 2000..Coronary artery surgery reduces re-infarction rates and mortality in patients with ischaemic heart disease. This study examines inequality in relation to primary care services... - Married couples' risk of same disease: cross sectional studyJulia Hippisley-Cox
Division of General Practice, School of Community Health Sciences, University of Nottingham, Nottingham NG7 2RD
BMJ 325:636. 2002.... - Do single handed practices offer poorer care? Cross sectional survey of processes and outcomesJ Hippisley-Cox
Division of General Practice, University of Nottingham, Nottingham NG7 2RD
BMJ 323:320-3. 2001..To determine whether there are important differences in performance between group practices and singlehanded general practitioners and the extent to which any differences are explained by practice characteristics such as deprivation... - QRESEARCH: a new general practice database for researchJulia Hippisley-Cox
Division of Primary Care, University of Nottingham, Nottingham, UK
Inform Prim Care 12:49-50. 2004 - Association between teenage pregnancy rates and the age and sex of general practitioners: cross sectional survey in Trent 1994-7J Hippisley-Cox
Division of General Practice, Medical School, Queen s Medical Centre, Nottingham NG7 2UH
BMJ 320:842-5. 2000..To examine variations in teenage pregnancy rates in Trent region and to determine possible associations with local general practice characteristics such as the age and sex of the doctors... - Prevalence, care, and outcomes for patients with diet-controlled diabetes in general practice: cross sectional surveyJ Hippisley-Cox
Division of General Practice, Tower Building University Park, Nottingham NG7 2RD, UK
Lancet 364:423-8. 2004..We aimed to establish the proportion with type 2 diabetes treated through diet only and to determine levels of complications and quality of care received compared with patients on hypoglycaemic medication... - Association of deprivation, ethnicity, and sex with quality indicators for diabetes: population based survey of 53,000 patients in primary careJulia Hippisley-Cox
Division of Primary Care, Tower Building, University Park, Nottingham NG2 7RD
BMJ 329:1267-9. 2004..To determine the effect of deprivation and ethnicity on the achievement of quality indicators for patients with diabetes and the extent of any inequalities between the sexes... - Risk of colorectal cancer in patients prescribed statins, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 inhibitors: nested case-control studyYana Vinogradova
Division of Primary Care, University of Nottingham, Nottingham, United Kingdom
Gastroenterology 133:393-402. 2007..Several studies suggest that statins prevent some cancers, with one study finding a 47% reduction in colorectal cancer risk after >or=5 years of regular use... - Accidental injury: a neglected area within Primary Care Groups and Trusts?Denise Kendrick
Division of General Practice, Floor 13, Tower Building, University Park, Nottingham NG7 2RD, UK
Health Educ Res 18:380-8. 2003..Gaps in knowledge about accidents and their prevention are apparent. PCG/Ts will need help and support to fully develop their potential in preventing accidental injuries... - A randomized controlled trial of the effect of providing information on accidental injury admissions and their costs to Primary Care Groups and TrustsCarol A C Coupland
Division of Primary Care, University of Nottingham, Tower Building, University Park, Nottingham, NG7 2RD, UK
Fam Pract 22:249-52. 2005..Primary Care Groups and Trusts (PCG/Ts) are responsible for improving the health of local populations, but there is little evidence of their strategic involvement in accident prevention... - Predicting risk of osteoporotic fracture in men and women in England and Wales: prospective derivation and validation of QFractureScoresJulia Hippisley-Cox
Division of Primary Care, Tower Building, University Park, Nottingham NG2 7RD
BMJ 339:b4229. 2009..To develop and validate two new fracture risk algorithms (QFractureScores) for estimating the individual risk of osteoporotic fracture or hip fracture over 10 years... - General practice characteristics associated with rates of testing and detection of hepatitis C: cross-sectional study in Nottingham and DerbyshireCarol Coupland
School of Community Health Sciences, Division of Primary Care, University of Nottingham, UK
Br J Gen Pract 56:620-3. 2006..Practices where at least half of the GPs were female had higher testing rates but lower positivity rates. The variation observed was not explained by deprivation or rurality of the practice... - Effects of severe mental illness on survival of people with diabetesYana Vinogradova
Department of Primary Care, Tower Building 13th Floor, University Park, University of Nottingham, Nottingham NG7 2RD, UK
Br J Psychiatry 197:272-7. 2010..People with mental health problems are more likely to die prematurely than the general population but no study has examined this in individuals with diabetes... - A comparison of research general practices and their patients with other practices--a cross-sectional survey in TrentVicky Hammersley
Division of General Practice, University of Nottingham
Br J Gen Pract 52:463-8. 2002..When interpreting results of studies undertaken by research networks we need to know how representative volunteer practices and their registered patients are of the total population of practices and patients in their locality... - Derivation, validation, and evaluation of a new QRISK model to estimate lifetime risk of cardiovascular disease: cohort study using QResearch databaseJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham NG2 7RD, UK
BMJ 341:c6624. 2010..To develop, validate, and evaluate a new QRISK model to estimate lifetime risk of cardiovascular disease... - Assisted delivery in the teenage population: the effect of inter-hospital variation, deprivation, and ageJane Allen
Division of Primary Care, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham, United Kingdom
Int J Adolesc Med Health 15:341-7. 2003..The objective was to determine the relationship between the risk of assisted delivery in women aged under 20 years and place of treatment, deprivation and age... - Teenagers at risk of unintended pregnancy: identification of practical risk markers for use in general practice from a retrospective analysis of case records in the United KingdomDick Churchill
Division of General Practice, University of Nottingham Medical School, Queen s Medical Centre, Nottingham, NG7 2UH, United Kingdom
Int J Adolesc Med Health 14:153-60. 2002..The findings from this study may assist primary care professionals in focussing opportunistic sexual health interventions at some teenagers who are at higher risk of unintended pregnancy... - Antidepressant use and risk of adverse outcomes in older people: population based cohort studyCarol Coupland
Division of Primary Care, University of Nottingham, Nottingham NG7 2RD, UK
BMJ 343:d4551. 2011..To investigate the association between antidepressant treatment and risk of several potential adverse outcomes in older people with depression and to examine risks by class of antidepressant, duration of use, and dose... - Risk of pneumonia in patients taking statins: population-based nested case-control studyYana Vinogradova
Division of Primary Care, University Park, Nottingham, UK
Br J Gen Pract 61:e742-8. 2011..Recent research suggests that statins might improve the outcome of infectious diseases because of their anti-oxidative and anti-inflammatory properties... - Severe traffic injuries to children, Trent, 1992-7: time trend analysisCarol Coupland
Division of Primary Care, University of Nottingham, Nottingham NG7 2RD, UK
BMJ 327:593-4. 2003 - Exposure to statins and risk of common cancers: a series of nested case-control studiesYana Vinogradova
Division of Primary Care, 13th Floor, Tower Building, University Park, Nottingham, NG2 7RD, UK
BMC Cancer 11:409. 2011..Many studies and meta-analyses have investigated the effects of statins on cancer incidence but without showing consistent effects... - Inequalities in uptake of influenza vaccine by deprivation and risk group: time trends analysisCarol Coupland
Division of Primary Care, Tower Building, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
Vaccine 25:7363-71. 2007..This general practice based study suggests that substantial increases in influenza vaccination rates have occurred across all risk groups, but that increased focus should be given to immunising high-risk patients below the age of 65... - Individualising the risks of statins in men and women in England and Wales: population-based cohort studyJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham, UK
Heart 96:939-47. 2010..To derive and validate risk algorithms so that the risks of four clinical outcomes associated with statin use can be estimated for individual patients... - Identification of new risk factors for pneumonia: population-based case-control studyYana Vinogradova
Division of Primary Care, University of Nottingham, Nottingham
Br J Gen Pract 59:e329-38. 2009..Certain conditions are established as risk factors for community-acquired pneumonia. There are a number of other conditions that may also be risk factors, but information on these is limited... - Exposure to bisphosphonates and risk of gastrointestinal cancers: series of nested case-control studies with QResearch and CPRD dataYana Vinogradova
Division of Primary Care, University Park, Nottingham NG2 7RD, UK
BMJ 346:f114. 2013..To investigate the association between use of bisphosphonates estimated from prescription information and risk of gastrointestinal cancers... - Exposure to bisphosphonates and risk of cancer: a protocol for nested case-control studies using the QResearch primary care databaseYana Vinogradova
Division of Primary Care, University of Nottingham, School of Community Health Sciences, Division of Primary Care, University Park, Nottingham, UK
BMJ Open 2:e000548. 2012..Conditional logistic regression will be applied to produce ORs adjusted for smoking status, socioeconomic status, ethnicity, cancer-specific co-morbidities and use of other medications... - Symptoms and risk factors to identify men with suspected cancer in primary care: derivation and validation of an algorithmJulia Hippisley-Cox
Division of Primary Care, Tower Building, University Park, Nottingham, NG2 7RD, UK
Br J Gen Pract 63:1-10. 2013..Early diagnosis of cancer could improve survival so better tools are needed... - Development and validation of risk prediction algorithm (QThrombosis) to estimate future risk of venous thromboembolism: prospective cohort studyJulia Hippisley-Cox
Division of Primary Care, University Park, Nottingham NG2 7RD, UK
BMJ 343:d4656. 2011..To derive and validate a new clinical risk prediction algorithm (QThrombosis, www.qthrombosis.org) to estimate individual patients' risk of venous thromboembolism... - Trends in the epidemiology and prescribing of medication for allergic rhinitis in EnglandNazim Ghouri
Ayr Hospital, UK
J R Soc Med 101:466-72. 2008..To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of symptom relief medication for allergic rhinitis in England... - Identifying undiagnosed diabetes: cross-sectional survey of 3.6 million patients' electronic recordsTim A Holt
Health Sciences Research Institute, University of Warwick, Coventry, CV4 7AL, UK
Br J Gen Pract 58:192-6. 2008..Around 1% of the UK population has diabetes that is either undiagnosed or unrecorded on practice disease registers... - Measuring performance and missing the point?Iona Heath
Caversham Group Practice, London NW5 2UP
BMJ 335:1075-6. 2007 - Rectal and postmenopausal bleeding: consultation and referral of patients with and without severe mental health problemsChris Parker
Nottingham Primary Care Research Partnership, Hucknall, Nottingham
Br J Gen Pract 57:371-6. 2007..There is concern that this could apply to rectal bleeding or postmenopausal bleeding. Published estimates of consultation rates and outcomes for these symptoms vary widely... - Developing a national primary care-based early warning system for health protection--a surveillance tool for the future? Analysis of routinely collected dataGillian Smith
Health Protection Agency West Midlands, 9th Floor Ladywood House, Birmingham B2 4DY, UK
J Public Health (Oxf) 29:75-82. 2007..The data were used 'real time' to reassure about lack of illness following the Buncefield Fuel Depot incident. This scheme is being further developed to provide daily local influenza-related information needed in an influenza pandemic... - Inequalities in access to care for patients with ischaemic heart diseaseJulia Hippisley-Cox
Br J Gen Pract 54:411-2. 2004 - Trends in national incidence, lifetime prevalence and adrenaline prescribing for anaphylaxis in EnglandAziz Sheikh
Allergy and Respiratory Research Group, Division of Community Health Sciences GP section, University of Edinburgh
J R Soc Med 101:139-43. 2008..Aim: To investigate recent trends in the recorded incidence, lifetime prevalence and prescribing of adrenaline for anaphylaxis in England...