S D Heys

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. doi request reprint Characterisation of tumour-infiltrating macrophages: impact on response and survival in patients receiving primary chemotherapy for breast cancer
    Steven D Heys
    Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
    Breast Cancer Res Treat 135:539-48. 2012
  2. pmc Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells
    Iain Brown
    Department of Surgery, University of Aberdeen, Medical School, Aberdeen, UK
    Breast Cancer Res 6:R601-7. 2004
  3. ncbi request reprint Nutrition and the surgical patient: triumphs and challenges
    S D Heys
    Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    Surgeon 3:139-44. 2005
  4. ncbi request reprint Neoadjuvant docetaxel in breast cancer: 3-year survival results from the Aberdeen trial
    Steven D Heys
    Department of Surgery, University of Aberdeen, Foresterhill, Scotland, UK
    Clin Breast Cancer 3:S69-74. 2002
  5. ncbi request reprint Peri-operative nutritional support: controversies and debates
    S D Heys
    University of Aberdeen, Scotland, UK
    Int J Surg Investig 2:107-15. 2000
  6. ncbi request reprint Primary docetaxel chemotherapy in patients with breast cancer: impact on response and survival
    Steven D Heys
    Department of Surgery, University of Aberdeen, Aberdeen, UK
    Breast Cancer Res Treat 90:169-85. 2005
  7. ncbi request reprint Immunonutrition in clinical practice: what is the current evidence?
    S D Heys
    Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, Scotland, UK
    Nutr Hosp 19:325-32. 2004
  8. ncbi request reprint Docetaxel as adjuvant and neoadjuvant treatment for patients with breast cancer
    Steven D Heys
    Department of Surgery, Medical Oncology University Medical Buildings, Foresterhill, Aberdeen, AB9 2ZD, UK
    Expert Opin Pharmacother 5:2147-57. 2004
  9. pmc Dietary supplementation with L-arginine in patients with breast cancer (> 4 cm) receiving multimodality treatment: report of a feasibility study
    J Brittenden
    Department of Surgery, University of Aberdeen, UK
    Br J Cancer 69:918-21. 1994
  10. ncbi request reprint Peri-operative acute phase response and cytokine releasein women with breast cancer: modulation bypolyadenylic-polyuridylic acid
    A L Khan
    Department of Surgery, University of Aberdeen, Aberdeen, Foresterhill, AB9 2ZD, UK
    Eur J Surg Oncol 25:574-9. 1999

Collaborators

Detail Information

Publications64

  1. doi request reprint Characterisation of tumour-infiltrating macrophages: impact on response and survival in patients receiving primary chemotherapy for breast cancer
    Steven D Heys
    Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
    Breast Cancer Res Treat 135:539-48. 2012
    ..The apparent impact of macrophage subsets on overall survival underlines the therapeutic potential of manipulating macrophage activation in cancer...
  2. pmc Reduced expression of p27 is a novel mechanism of docetaxel resistance in breast cancer cells
    Iain Brown
    Department of Surgery, University of Aberdeen, Medical School, Aberdeen, UK
    Breast Cancer Res 6:R601-7. 2004
    ..However, apoptosis and cell cycle regulation are key mechanisms by which most chemotherapeutic agents exert their cytotoxic effects...
  3. ncbi request reprint Nutrition and the surgical patient: triumphs and challenges
    S D Heys
    Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    Surgeon 3:139-44. 2005
    ....
  4. ncbi request reprint Neoadjuvant docetaxel in breast cancer: 3-year survival results from the Aberdeen trial
    Steven D Heys
    Department of Surgery, University of Aberdeen, Foresterhill, Scotland, UK
    Clin Breast Cancer 3:S69-74. 2002
    ..It is important to note that this was a small study, and the survival results should be interpreted with caution. The results are encouraging, however, and further studies are urgently required...
  5. ncbi request reprint Peri-operative nutritional support: controversies and debates
    S D Heys
    University of Aberdeen, Scotland, UK
    Int J Surg Investig 2:107-15. 2000
    ..However, the benefits of this approach have been debated and as we enter the new millennium there are many questions regarding then role of peri-operative nutritional support that remain unanswered...
  6. ncbi request reprint Primary docetaxel chemotherapy in patients with breast cancer: impact on response and survival
    Steven D Heys
    Department of Surgery, University of Aberdeen, Aberdeen, UK
    Breast Cancer Res Treat 90:169-85. 2005
    ..Non-anthracycline docetaxel-based primary regimens have shown early promise. As we continue to define the optimal regimen, a growing body of evidence supports the use of docetaxel in primary chemotherapeutic regimens for breast cancer...
  7. ncbi request reprint Immunonutrition in clinical practice: what is the current evidence?
    S D Heys
    Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, Scotland, UK
    Nutr Hosp 19:325-32. 2004
    ..The indications are that immunonutrition has the potential to help patients but its place must be more clearly defined before its widespread acceptance into clinical practice is based on sound scientific evidence...
  8. ncbi request reprint Docetaxel as adjuvant and neoadjuvant treatment for patients with breast cancer
    Steven D Heys
    Department of Surgery, Medical Oncology University Medical Buildings, Foresterhill, Aberdeen, AB9 2ZD, UK
    Expert Opin Pharmacother 5:2147-57. 2004
    ..In the neoadjuvant setting, the addition of docetaxel to standard regimens does increase pathological response rates, which is a surrogate marker of eventual outcome...
  9. pmc Dietary supplementation with L-arginine in patients with breast cancer (> 4 cm) receiving multimodality treatment: report of a feasibility study
    J Brittenden
    Department of Surgery, University of Aberdeen, UK
    Br J Cancer 69:918-21. 1994
    ..Further studies are now required to evaluate the potential beneficial use of nutritional pharmacology in combination with existing treatment regimens...
  10. ncbi request reprint Peri-operative acute phase response and cytokine releasein women with breast cancer: modulation bypolyadenylic-polyuridylic acid
    A L Khan
    Department of Surgery, University of Aberdeen, Aberdeen, Foresterhill, AB9 2ZD, UK
    Eur J Surg Oncol 25:574-9. 1999
    ..CONCLUSIONS: This modulation of acute phase response may have important implications for patients with cancer undergoing surgery...
  11. pmc In vivo cytokine production and recombinant interleukin 2 immunotherapy: an insight into the possible mechanisms underlying clinical responses
    D J Deehan
    Department of Surgery, University of Aberdeen, Scotland, UK
    Br J Cancer 69:1130-5. 1994
    ..Differential production and/or release of cytokines and prostaglandins, during therapy, further determined the likelihood of response to rIL-2...
  12. ncbi request reprint A pilot study with long term follow up of hyperbaric oxygen pretreatment in patients with locally advanced breast cancer undergoing neo-adjuvant chemotherapy
    S D Heys
    Department of Surgery, University of Aberdeen, Scotland
    Undersea Hyperb Med 33:33-43. 2006
    ..Five year survival in those who tolerated the trial regime was 73% and did not differ between the groups. This mortality was cancer related...
  13. ncbi request reprint Polyadenylic-polyuridylic acid enhances the natural cell-mediated cytotoxicity in patients with breast cancer undergoing mastectomy
    A L Khan
    Department of Surgery, University of Aberdeen, Medical School, Scotland
    Surgery 118:531-8. 1995
    ..This may have important implications for patients with cancer undergoing major operation...
  14. doi request reprint The biological correlates of macroscopic breast tumour structure measured using fractal analysis in patients undergoing neoadjuvant chemotherapy
    P Di Giovanni
    Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK
    Breast Cancer Res Treat 133:1199-206. 2012
    ....
  15. pmc Psychological, clinical and pathological effects of relaxation training and guided imagery during primary chemotherapy
    L G Walker
    Behavioural Oncology Unit, University of Aberdeen, Medical School, Foresterhill, UK
    Br J Cancer 80:262-8. 1999
    ..These simple, inexpensive and beneficial interventions should be offered to patients wishing to improve quality of life during primary chemotherapy...
  16. ncbi request reprint Can patients' likelihood of benefiting from primary chemotherapy for breast cancer be predicted before commencement of treatment?
    Keith N Ogston
    Department of Surgery, University of Aberdeen, UK
    Breast Cancer Res Treat 86:181-9. 2004
    ....
  17. doi request reprint The use of FDG-PET in assessing axillary lymph node status in breast cancer: a systematic review and meta-analysis of the literature
    Rebecca Peare
    Department of Nuclear Medicine, Aberdeen Royal, Infirmary, Aberdeen AB25 2ZD, UK
    Breast Cancer Res Treat 123:281-90. 2010
    ..Moreover, the additional benefit of an assessment of distal metastatic spread provided by FDG-PET requires further investigation...
  18. ncbi request reprint Local recurrence in patients with large and locally advanced breast cancer treated with primary chemotherapy
    Stuart A McIntosh
    Aberdeen Breast Unit, Ward 34, Aberdeen Royal Infirmary and University of Aberdeen, Foresterhill, AB25 2ZN, Aberdeen, Scotland, United Kingdom
    Am J Surg 185:525-31. 2003
    ....
  19. ncbi request reprint Neoadjuvant docetaxel in locally advanced breast cancer
    Andrew W Hutcheon
    University of Aberdeen Hospital, Aberdeen, Scotland
    Breast Cancer Res Treat 79:S19-24. 2003
    ..These data and data from the NSABP B-27 and GEPAR-duo trials strongly support a combined anthracycline/docetaxel regimen in the neoadjuvant setting...
  20. ncbi request reprint A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival
    Keith N Ogston
    Section of Surgical Oncology, University of Aberdeen, Foresterhill, Aberdeen, Scotland AB9 2ZD, UK
    Breast 12:320-7. 2003
    ....
  21. doi request reprint Regulation of fatty acid synthase (FAS) and apoptosis in estrogen-receptor positive and negative breast cancer cells by conjugated linoleic acids
    H J Song
    School of Life Science, The Robert Gordon University, Aberdeen, AB10 1JQ, UK
    Prostaglandins Leukot Essent Fatty Acids 87:197-203. 2012
    ..Sterol regulatory element binding proteins (SREBPs) are transcription factors that regulate genes involved in lipid metabolism, including FAS...
  22. ncbi request reprint Synthetic polyribonucleotides: current role and potential use in oncological practice
    A L Khan
    Department of Surgery, University of Aberdeen, UK
    Eur J Surg Oncol 21:224-7. 1995
    ..PAPU, therefore, merits further careful consideration and evaluation. This article reviews its present status and considers further priority areas for investigation...
  23. ncbi request reprint Effect of CLA supplementation on immune function in young healthy volunteers
    H J Song
    Rowett Research Institute, Aberdeen, UK
    Eur J Clin Nutr 59:508-17. 2005
    ..This study investigated the effect of dietary CLA supplementation (3g/day; 50:50 mix of the two major isomers) on the immune system and plasma lipids and glucose of healthy human (male and female) volunteers...
  24. doi request reprint Docosahexaenoic acid enhances the efficacy of docetaxel in prostate cancer cells by modulation of apoptosis: the role of genes associated with the NF-kappaB pathway
    Irshad A A Shaikh
    School of Medicine and Dentistry, Cancer Medicine Research Group, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    Prostate 68:1635-46. 2008
    ..Evidence for similar effects in prostate cancer is lacking. We investigated the effects of docosahexaenoic acid (DHA-22:6n-3), a component of fish oil, on the cytotoxicity of docetaxel in prostate cancer cells...
  25. doi request reprint Complementary and alternative medicines use by Scottish women with breast cancer. What, why and the potential for drug interactions?
    J S McLay
    Division of Applied Health Sciences, University of Aberdeen, Aberdeen AB25 2ZG, UK
    Eur J Clin Pharmacol 68:811-9. 2012
    ..Despite the increased use of complementary and alternative medicine (CAM) by breast cancer patients, there is little published information regarding CAM use in the Scottish breast cancer population...
  26. ncbi request reprint Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administration
    S I K Semple
    Department of Radiology, University of Aberdeen, Scotland, UK
    Ann Oncol 17:1393-8. 2006
    ..Reduction in (18)F-FDG PET metabolism has previously been shown to correlate with histological response to primary chemotherapy...
  27. ncbi request reprint Distal proctocolitis and n-3 polyunsaturated fatty acids (n-3 PUFAs): the mucosal effect in situ
    Y Z Almallah
    Department of Surgery, University of Aberdeen, United Kingdom
    J Clin Immunol 20:68-76. 2000
    ..This may have important implication for therapy in patients with ulcerative colitis...
  28. ncbi request reprint What is achieved by mammographic surveillance after breast conservation treatment for breast cancer?
    F Ashkanani
    Department of Surgery, University of Aberdeen, Aberdeen, UK
    Am J Surg 182:207-10. 2001
    ..This study has investigated this aspect and, in particular, whether mammography or clinical examination or both allowed an early detection of recurrence of the disease in the conserved breast...
  29. ncbi request reprint Positron emission tomography using [(18)F]-fluorodeoxy-D-glucose to predict the pathologic response of breast cancer to primary chemotherapy
    I C Smith
    John Mallard Scottish Positron Emission Tomography Center, Scotland, United Kingdom
    J Clin Oncol 18:1676-88. 2000
    ..To determine whether [(18)F]-fluorodeoxy-D-glucose ([(18)F]-FDG) positron emission tomography (PET) can predict the pathologic response of primary and metastatic breast cancer to chemotherapy...
  30. pmc Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines
    Iain Brown
    Cancer Medicine Research Programme, Translational Medical Sciences, Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Polwarth Building, Aberdeen, AB25 2ZD, UK
    Carcinogenesis 31:1584-91. 2010
    ..Our findings suggest that the expression of cannabinoid receptors and of FAAH in some tumour cells could well influence the effectiveness of DHA and EPA or their ethanolamide derivatives as anticancer agents...
  31. ncbi request reprint Neoadjuvant chemotherapy in breast cancer: significantly enhanced response with docetaxel
    Ian C Smith
    Department of Academic Radiology, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom
    J Clin Oncol 20:1456-66. 2002
    ..To compare the efficacy of neoadjuvant (NA) docetaxel (DOC) with anthracycline-based therapy and determine the efficacy of NA DOC in patients with breast cancer initially failing to respond to anthracycline-based NA chemotherapy (CT)...
  32. doi request reprint Genetic polymorphism in ornithine decarboxylase and risk of breast cancer
    Iain Brown
    School of Medicine and Dentistry, College of Life Sciences and Medicine, University of Aberdeen, Medical School, Foresterhill, Aberdeen AB25 2ZD, UK
    Fam Cancer 8:307-11. 2009
    ..In sporadic breast cancer, the presence of at least one A allele is protective against the disease. The influence of this polymorphism may be less important in individuals with an inherited breast cancer predisposition...
  33. doi request reprint Inhibition of gastric cancer cell growth by arginine: molecular mechanisms of action
    Shayanthan Nanthakumaran
    School of Medicine and Dentistry, College of Life Sciences and Medicine, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    Clin Nutr 28:65-70. 2009
    ..The aim of this study was to investigate the effects of arginine on tumour cell growth, invasion and modulation of expression of genes involved in these aspects of cell behaviour...
  34. doi request reprint Profiling the expression of cytochrome P450 in breast cancer
    Graeme I Murray
    Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, UK
    Histopathology 57:202-11. 2010
    ..The aim was to define the P450 expression profile in breast cancer and establish the significance of P450 expression in this tumour type...
  35. ncbi request reprint Good for them or good for us? The role of academic guidance interviews
    Alan R Denison
    School of Medicine, University of Aberdeen, Aberdeen, UK
    Med Educ 40:1188-91. 2006
    ..Early recognition and support of struggling students is crucial if they are to avoid subsequent failure at high stakes assessments...
  36. ncbi request reprint Alterations of beta-tubulin isotypes in breast cancer cells resistant to docetaxel
    Kawan Shalli
    School of Medicine, College of Life Sciences and Medicine, University of Aberdeen, Medical School, Foresterhill, Aberdeen, UK
    FASEB J 19:1299-301. 2005
    ..This allows further understanding and elucidation of mechanisms involved in resistance to docetaxel...
  37. ncbi request reprint Genomic changes identified by comparative genomic hybridisation in docetaxel-resistant breast cancer cell lines
    Sarah L McDonald
    School of Medicine, College of Life Sciences and Medicine, University of Aberdeen, Medical School, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
    Eur J Cancer 41:1086-94. 2005
    ..This study is the first description of a genomic approach specifically to identify genomic regions involved in resistance to docetaxel...
  38. ncbi request reprint The relationship between vascular and metabolic characteristics of primary breast tumours
    Scott I K Semple
    Department of Radiology, University of Aberdeen, Lilian Sutton Building, AB252ZD Aberdeen, Scotland, UK
    Eur Radiol 14:2038-45. 2004
    ..MRI and PET provide methods of assessing breast tumour vascularity and metabolism in vivo using the exchange rate constants of dynamic MRI, and DUR of PET, respectively, these measures being related but not equivalent...
  39. doi request reprint Enhancing cytotoxic therapies for breast and prostate cancers with polyunsaturated fatty acids
    Irshad A A Shaikh
    Cancer Medicine Group, Division of Applied Medicine, Medical School, University of Aberdeen, Aberdeen, UK
    Nutr Cancer 62:284-96. 2010
    ..It concludes that sufficient evidence is available to suggest that major clinical trials with these natural compounds as adjuncts to standard therapies should be undertaken as a priority...
  40. ncbi request reprint Correlation of MRI/PET rim enhancement in breast cancer: a delivery related phenomenon with therapy implications?
    Scott I K Semple
    Department of Radiology, University of Aberdeen, Foresterhill, Scotland, UK
    Lancet Oncol 4:759. 2003
  41. ncbi request reprint Plant phenolics in the prevention and treatment of cancer
    Klaus W J Wahle
    Cancer Medicine Research Group, School of Medicine and Dentistry, Aberdeen University, Aberdeen, UK
    Adv Exp Med Biol 698:36-51. 2010
    ..Much of the work in vitro with phenolic compounds has utilized concentrations higher than the amount that can be obtained from the diet suggesting a role of fortified, functional foods in cancer suppression...
  42. ncbi request reprint Guidance for the management of breast cancer treatment-induced bone loss: a consensus position statement from a UK Expert Group
    David M Reid
    Department of Rheumatology, University of Aberdeen, United Kingdom
    Cancer Treat Rev 34:S3-18. 2008
    ..Management recommendations have been summarised in two algorithms, one for women experiencing a premature menopause and the other for postmenopausal women requiring adjuvant aromatase inhibitor therapy...
  43. ncbi request reprint Immunohistochemical detection of a germline BRCA1 mutation in a breast and ovarian cancer family
    A C Schofied
    Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen AB25 2ZD, UK
    Breast 9:286-91. 2000
    ..Further mutation studies in early-onset breast cancer group will be necessary to evaluate the use of immunohistochemistry as a rapid, initial screening technique to identify BRCA1 mutations...
  44. doi request reprint Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines
    I Brown
    Translational Medical Sciences, Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, AB25 2ZD, UK
    Prostaglandins Leukot Essent Fatty Acids 85:305-10. 2011
    ..This could have important implications for the use of n-3 fatty acids as therapeutic agents in breast and prostate cancers expressing cannabinoid receptors...
  45. ncbi request reprint Potentiation of the anti-tumour effect of docetaxel by conjugated linoleic acids (CLAs) in breast cancer cells in vitro
    Alemu Fite
    Section of Surgical Oncology, Department of Surgery, University of Aberdeen, Medical School, Foresterhill, Aberdeen, Aberdeen, Scotland, UK
    Prostaglandins Leukot Essent Fatty Acids 77:87-96. 2007
    ..Results show that CLA isomers augment anti-tumour effects of docetaxel in breast cancer cells and suggest possible dual treatment regimens...
  46. pmc Interleukin 2 therapy in cancer: identification of responders
    J Broom
    Department of Clinical Biochemistry, University of Aberdeen, Scotland, UK
    Br J Cancer 66:1185-7. 1992
    ..e.m, P = 0.014). These findings suggest that it is possible to predict those cancer patients who are most likely to respond to and benefit from rIL2 therapy, either prior to the commencement of or during the first course of rIL2...
  47. doi request reprint Impaired expression of glutathione peroxidase-4 gene in peripheral blood mononuclear cells: a biomarker of increased breast cancer risk
    G Bermano
    School of Life Sciences, The Robert Gordon University, Aberdeen, UK
    Cancer Biomark 7:39-46. 2010
    ..Attenuation of GPX4 mRNA expression in PBMNC suggests this could be a simple,early biomarker for future breast cancer risk in the high proportion of women without known risk factors who eventually contract the disease...
  48. ncbi request reprint Psychosocial aspects of cancer in the elderly
    L G Walker
    Department of Mental Health, Medical School, University of Aberdeen, UK
    Eur J Surg Oncol 24:375-8. 1998
    ....
  49. ncbi request reprint Alterations in polyamine catabolic enzymes in human breast cancer tissue
    H M Wallace
    Department of Medicine, University of Aberdeen, Foresterhill, United Kingdom
    Clin Cancer Res 6:3657-61. 2000
    ..Therefore, drugs that induce PAO activity may be a novel means of attacking tumor cells...
  50. ncbi request reprint Breast cancer in women aged 35 and under: prognosis and survival
    S Jmor
    Department of Surgery, University of Aberdeen, Foresterhill, Aberdeen, UK
    J R Coll Surg Edinb 47:693-9. 2002
    ..This study has audited clinical and pathological features in patients aged 35 years and under with breast cancer...
  51. ncbi request reprint Immunonutrition
    H J Kirk
    Section of Surgical Oncology, University of Aberdeen, University Medical Buildings, Foresterhill, Aberdeen AB25 2ZD, UK
    Br J Surg 90:1459-60. 2003
  52. ncbi request reprint Monitoring primary breast cancer throughout chemotherapy using FDG-PET
    Garry M McDermott
    School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
    Breast Cancer Res Treat 102:75-84. 2007
    ..The purpose was to determine whether there is an optimal method for defining tumour volume and an optimal imaging time for predicting pathologic chemotherapy response...
  53. ncbi request reprint Patterns of local and distant disease relapse in patients with breast cancer treated with primary chemotherapy: do patients with a complete pathological response differ from those with residual tumour in the breast?
    Shailesh Chaturvedi
    Department of Surgery, Medical School, University of Aberdeen, UK
    Breast Cancer Res Treat 93:151-8. 2005
    ..A complete pathological response is associated with fewer local and distant recurrences as well as improved survival although there are no differences in time to development of metastatic relapse...
  54. ncbi request reprint Fatty acid regulation of protein kinase C isoforms in prostate cancer cells
    S S Pandian
    Department of Surgical Oncology, University of Aberdeen, Scotland, AB 25 9ZD, United Kingdom
    Biochem Biophys Res Commun 283:806-12. 2001
    ..Fatty acids enhanced cytosolic PKC-iota abundance but only EPA and to a lesser extent LA increased its membrane content. Changes in PKC-delta, -iota, and -gamma did not affect PSA production...
  55. doi request reprint Moving inwards, moving outwards, moving upwards: the role of spirituality during the early stages of breast cancer
    J Swinton
    School of Divinity, History and Philosophy, King s College University of Aberdeen, Aberdeen, UK
    Eur J Cancer Care (Engl) 20:640-52. 2011
    ....
  56. ncbi request reprint Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR)
    L Sharp
    Epidemiology Group, Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill House Annex, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
    Cancer Lett 181:65-71. 2002
    ..Patterns in risk with regard to genotype and folate combinations are broadly similar those reported for colorectal neoplasia. The roles of MTHFR and folate in breast cancer aetiology are likely to be complex...
  57. ncbi request reprint Immune suppression and isolated severe head injury: a significant clinical problem
    D E Boddie
    Section of Surgical Oncology, Department of Surgery, University of Aberdeen, Aberdeen, Scotland, UK
    Br J Neurosurg 17:405-17. 2003
    ....
  58. ncbi request reprint Conjugated linoleic acids (CLAs) regulate the expression of key apoptotic genes in human breast cancer cells
    Barun Majumder
    Unit of Surgical Oncology, Aberdeen University Medical School, Foresterhill, Aberdeen AB25 9ZD, Scotland
    FASEB J 16:1447-9. 2002
    ..Findings indicate that CLA elicits mainly proapoptotic effects in human breast tumor cells through both p53-dependent and p53-independent pathways, according to cell type...
  59. ncbi request reprint Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells
    Hyun Ju Song
    The Rowett Research Institute, Bucksburn, Aberdeen, Scotland, UK
    Nutr Cancer 49:100-8. 2004
    ..Increased PKC-delta and decreased PKC-iota membrane abundance was consistent with CLAs eliciting increased apoptosis and, in part, with their antitumor effects...
  60. ncbi request reprint Cell signal mechanisms, conjugated linoleic acids (CLAs) and anti-tumorigenesis
    K W J Wahle
    Rowett Research Institut, Bucksburn, Aberdeen, Scotland, UK
    Prostaglandins Leukot Essent Fatty Acids 67:183-6. 2002
    ..These findings support the anticancer effects of CLA found in animal models and indicate similar effects could occur in man...
  61. ncbi request reprint Factor analysis can be a useful standard setting tool in a high stakes OSCE assessment
    Alistair M S Chesser
    University of Aberdeen, Aberdeen, Scotland, UK
    Med Educ 38:825-31. 2004
    ..Using scores aggregated across stations risks allowing students who are incompetent in some core skills to pass an examination, which may not be acceptable for high stakes assessments...
  62. ncbi request reprint Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid
    Hyun Ju Song
    The Robert Gordon University, School of Life Sciences, St Andrews Street, Aberdeen, United Kingdom
    Prostate 66:839-46. 2006
    ..The present study investigated the effects of CLAs (cis-9, trans-11, and trans-10, cis-12 isomers and a 50:50 mixture) on apoptosis and NF-kappaB activation in LNCaP cells...