Ewald H Hettema

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. pmc Yeast peroxisomes multiply by growth and division
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, England, UK
    J Cell Biol 178:399-410. 2007
  2. pmc How peroxisomes multiply
    Ewald H Hettema
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    J Cell Sci 122:2331-6. 2009
  3. pmc Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK
    EMBO J 31:2852-68. 2012
  4. pmc A dual function for Pex3p in peroxisome formation and inheritance
    Joanne M Munck
    Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, England, UK
    J Cell Biol 187:463-71. 2009
  5. pmc Dnm1p-dependent peroxisome fission requires Caf4p, Mdv1p and Fis1p
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield, S10 2TN, UK
    J Cell Sci 121:1633-40. 2008
  6. pmc Atg36: the Saccharomyces cerevisiae receptor for pexophagy
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK
    Autophagy 8:1680-1. 2012
  7. pmc Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum
    James M Nuttall
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    Biochem J 447:353-61. 2012
  8. pmc A role for the dynamin-like protein Vps1 during endocytosis in yeast
    Iwona I Smaczynska-de Rooij
    Department of Molecular Biology and Biotechnology, Firth Court, University of Sheffield, Sheffield S102TN, UK
    J Cell Sci 123:3496-506. 2010
  9. doi request reprint Peroxisome biogenesis: recent advances
    James M Nuttall
    Dept Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
    Curr Opin Cell Biol 23:421-6. 2011

Collaborators

  • Martin W Goldberg
  • Alison M Motley
  • James M Nuttall
  • Iwona I Smaczynska-de Rooij
  • Joanne M Munck
  • Donald J Watts
  • Alison Motley
  • Ellen G Allwood
  • Soheil Aghamohammadzadeh
  • Kathryn R Ayscough
  • Gemma P Ward

Detail Information

Publications9

  1. pmc Yeast peroxisomes multiply by growth and division
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, England, UK
    J Cell Biol 178:399-410. 2007
    ..Our results show that peroxisomes multiply by growth and division under our assay conditions. We conclude that the ER to peroxisome pathway functions to supply existing peroxisomes with essential membrane constituents...
  2. pmc How peroxisomes multiply
    Ewald H Hettema
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    J Cell Sci 122:2331-6. 2009
    ....
  3. pmc Pex3-anchored Atg36 tags peroxisomes for degradation in Saccharomyces cerevisiae
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK
    EMBO J 31:2852-68. 2012
    ..We conclude that Pex3 recruits the pexophagy receptor Atg36. This reinforces the pivotal role played by Pex3 in coordinating the size of the peroxisome pool, and establishes its role in pexophagy in S. cerevisiae...
  4. pmc A dual function for Pex3p in peroxisome formation and inheritance
    Joanne M Munck
    Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield S10 2TN, England, UK
    J Cell Biol 187:463-71. 2009
    ..We conclude that Pex3p functions as an anchor for Inp1p at the peroxisomal membrane, and that this function is independent of its role at the ER in peroxisome biogenesis...
  5. pmc Dnm1p-dependent peroxisome fission requires Caf4p, Mdv1p and Fis1p
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield, S10 2TN, UK
    J Cell Sci 121:1633-40. 2008
    ....
  6. pmc Atg36: the Saccharomyces cerevisiae receptor for pexophagy
    Alison M Motley
    Department of Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield, UK
    Autophagy 8:1680-1. 2012
    ..Our recent findings suggest that Atg36 is a novel pexophagy receptor that may target peroxisomes for degradation via a noncanonical mechanism...
  7. pmc Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum
    James M Nuttall
    Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, UK
    Biochem J 447:353-61. 2012
    ..The peroxisomal location of FDPS in D. discoideum indicates that NBPs have to cross the peroxisomal membrane before they can bind to their target...
  8. pmc A role for the dynamin-like protein Vps1 during endocytosis in yeast
    Iwona I Smaczynska-de Rooij
    Department of Molecular Biology and Biotechnology, Firth Court, University of Sheffield, Sheffield S102TN, UK
    J Cell Sci 123:3496-506. 2010
    ..Vps1 mutants were generated, and analysis in several assays reveals a role for the C-terminal self-assembly domain in endocytosis but not in other membrane fission events with which Vps1 has previously been associated...
  9. doi request reprint Peroxisome biogenesis: recent advances
    James M Nuttall
    Dept Molecular Biology and Biotechnology, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
    Curr Opin Cell Biol 23:421-6. 2011
    ..In this minireview, we focus mainly on PMP biogenesis, and highlight recent advances in peroxisomal matrix protein import, fission and segregation in yeast...