Ariane L Herrick

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi request reprint Acute intermittent porphyria
    Ariane L Herrick
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Best Pract Res Clin Gastroenterol 19:235-49. 2005
  2. pmc Genetic epidemiology: systemic sclerosis
    Ariane L Herrick
    Arthritis Research Campaign Epidemiology Unit, University of Manchester, UK
    Arthritis Res 4:165-8. 2002
  3. ncbi request reprint Development of agents for the treatment of systemic sclerosis
    A L Herrick
    Rheumatic Diseases Centre, Hope Hospital, University of Manchester Medical School, Manchester, M13 9PT, UK
    Expert Opin Investig Drugs 10:1255-64. 2001
  4. ncbi request reprint Pathogenesis of Raynaud's phenomenon
    A L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 44:587-96. 2005
  5. ncbi request reprint Vascular function in systemic sclerosis
    A L Herrick
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Curr Opin Rheumatol 12:527-33. 2000
  6. ncbi request reprint A double-blind placebo-controlled trial of antioxidant therapy in limited cutaneous systemic sclerosis
    A L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Clin Exp Rheumatol 18:349-56. 2000
  7. ncbi request reprint Treatment of Raynaud's phenomenon: new insights and developments
    Ariane L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Curr Rheumatol Rep 5:168-74. 2003
  8. doi request reprint Noninvasive imaging techniques in the assessment of scleroderma spectrum disorders
    Andrea K Murray
    School of Translational Medicine, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK
    Arthritis Rheum 61:1103-11. 2009
  9. doi request reprint The influence of measurement location on reliability of quantitative nailfold videocapillaroscopy in patients with SSc
    Andrea K Murray
    Clinical Sciences Building, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 51:1323-30. 2012
  10. doi request reprint Nail-fold capillary abnormalities are associated with anti-centromere antibody and severity of digital ischaemia
    Ariane L Herrick
    The University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 49:1776-82. 2010

Detail Information

Publications59

  1. ncbi request reprint Acute intermittent porphyria
    Ariane L Herrick
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Best Pract Res Clin Gastroenterol 19:235-49. 2005
    ..Finally we discuss management, including family screening, avoidance of triggering factors, analgesia, maintenance of a high calorie intake, and administration of haem derivatives...
  2. pmc Genetic epidemiology: systemic sclerosis
    Ariane L Herrick
    Arthritis Research Campaign Epidemiology Unit, University of Manchester, UK
    Arthritis Res 4:165-8. 2002
    ..Recent advances in genetic methodologies should further our understanding of this complex disease process...
  3. ncbi request reprint Development of agents for the treatment of systemic sclerosis
    A L Herrick
    Rheumatic Diseases Centre, Hope Hospital, University of Manchester Medical School, Manchester, M13 9PT, UK
    Expert Opin Investig Drugs 10:1255-64. 2001
    ..Conversely, it is to be hoped that in the future, drugs shown to be effective in SSc might prove beneficial for other fibrotic diseases...
  4. ncbi request reprint Pathogenesis of Raynaud's phenomenon
    A L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 44:587-96. 2005
    ..As our understanding of the pathophysiology of Raynaud's phenomenon increases, so do our possibilities for identifying effective treatments...
  5. ncbi request reprint Vascular function in systemic sclerosis
    A L Herrick
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Curr Opin Rheumatol 12:527-33. 2000
    ....
  6. ncbi request reprint A double-blind placebo-controlled trial of antioxidant therapy in limited cutaneous systemic sclerosis
    A L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Clin Exp Rheumatol 18:349-56. 2000
    ..To evaluate the effects of a combination of micronutrient antioxidants (selenium, beta-carotene, vitamin C, vitamin E and methionine) with allopurinol in patients with limited cutaneous systemic sclerosis (SSc)...
  7. ncbi request reprint Treatment of Raynaud's phenomenon: new insights and developments
    Ariane L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Curr Rheumatol Rep 5:168-74. 2003
    ..The necessity of prompt assessment and treatment of acute digital ischemia, which is a medical emergency, is highlighted...
  8. doi request reprint Noninvasive imaging techniques in the assessment of scleroderma spectrum disorders
    Andrea K Murray
    School of Translational Medicine, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK
    Arthritis Rheum 61:1103-11. 2009
    ....
  9. doi request reprint The influence of measurement location on reliability of quantitative nailfold videocapillaroscopy in patients with SSc
    Andrea K Murray
    Clinical Sciences Building, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 51:1323-30. 2012
    ..However, it requires further validation. Our aim was to assess the inter-observer, intra-observer and test-retest variability of semi-automated measurement of capillary features as well as of a manual density measurement...
  10. doi request reprint Nail-fold capillary abnormalities are associated with anti-centromere antibody and severity of digital ischaemia
    Ariane L Herrick
    The University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 49:1776-82. 2010
    ..v. vasodilators, debridements or amputations), (ii) a positive ACA, (iii) clinically evident calcinosis, (iv) pulmonary arterial hypertension and (v) telangiectases...
  11. ncbi request reprint A double-blind, randomized, placebo-controlled crossover trial of the α2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis
    Ariane L Herrick
    Clinical Sciences Building, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 53:948-52. 2014
    ..Secondary objectives were to assess safety and tolerability...
  12. doi request reprint Reliability of dermoscopy in the assessment of patients with Raynaud's phenomenon
    Tonia L Moore
    Salford Royal NHS Foundation Trust, Salford M6 8HD, UK
    Rheumatology (Oxford) 49:542-7. 2010
    ..Good reliability is a necessary prerequisite for a test to be a valid clinical or research tool...
  13. doi request reprint Preliminary clinical evaluation of semi-automated nailfold capillaroscopy in the assessment of patients with Raynaud's phenomenon
    Andrea K Murray
    School of Translational Medicine, The University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK
    Microcirculation 18:440-7. 2011
    ..Our aim was to compare semi-automatic feature measurement from newly developed software with manual measurements, and determine the degree to which semi-automated data allows disease group classification...
  14. doi request reprint Clinical features of childhood localized scleroderma in an incidence cohort
    Ariane L Herrick
    Arthritis Research UK Epidemiology Unit, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Rheumatology (Oxford) 50:1865-8. 2011
    ..Our aim was to describe clinical features and pattern of care in children with localized scleroderma presenting to secondary care during a 25-month incidence study...
  15. doi request reprint Quantitative nailfold video capillaroscopy in patients with idiopathic inflammatory myopathy
    Louise K Mercer
    ARC Epidemiology Unit, University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK
    Rheumatology (Oxford) 49:1699-705. 2010
    ....
  16. doi request reprint Contemporary management of Raynaud's phenomenon and digital ischaemic complications
    Ariane L Herrick
    The University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Salford, UK
    Curr Opin Rheumatol 23:555-61. 2011
    ..New approaches to therapy are being driven by increased understanding of pathophysiology and by increased international networking of clinicians and scientists, facilitating clinical trials...
  17. doi request reprint Therapy: A local approach to Raynaud phenomenon
    Ariane L Herrick
    University of Manchester and Salford Royal Hospital, Salford, Manchester, UK
    Nat Rev Rheumatol 5:246-7. 2009
    ..Topical, or transdermal, treatments that increase digital blood flow without systemic adverse effects are, therefore, an attractive option. A novel topical nitroglycerin formulation has shown promise in treating Raynaud attacks...
  18. doi request reprint Expression of advanced glycation end products and their receptor in skin from patients with systemic sclerosis with and without calcinosis
    Christine A Davies
    Tissue Injury and Repair Research Group, Research School of Clinical and Laboratory Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK
    Rheumatology (Oxford) 48:876-82. 2009
    ....
  19. ncbi request reprint Digital iontophoresis of vasoactive substances as measured by laser Doppler imaging--a non-invasive technique by which to measure microvascular dysfunction in Raynaud's phenomenon
    M E Anderson
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 43:986-91. 2004
    ....
  20. ncbi request reprint A pilot study of body image dissatisfaction and the psychological impact of systemic sclerosis-related telangiectases
    Holly Ennis
    Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academic Health Science Center, Manchester, UK
    Clin Exp Rheumatol 31:12-7. 2013
    ....
  21. doi request reprint Management of Raynaud's phenomenon and digital ischemia
    Ariane L Herrick
    Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, University of Manchester, Salford M6 8HD, UK
    Curr Rheumatol Rep 15:303. 2013
    ..Increased availability and interest in nailfold capillaroscopy, by facilitating early diagnosis of SSc, should pave the way for studies of early intervention and vascular protection...
  22. doi request reprint Modified-release sildenafil reduces Raynaud's phenomenon attack frequency in limited cutaneous systemic sclerosis
    Ariane L Herrick
    University of Manchester, Manchester Academic Health Science Centre, Salford Royal Hospital, Salford, UK
    Arthritis Rheum 63:775-82. 2011
    ..To examine the effect of sildenafil in patients with Raynaud's phenomenon (RP) secondary to limited cutaneous systemic sclerosis (lcSSc)...
  23. doi request reprint Acro-osteolysis in systemic sclerosis is associated with digital ischaemia and severe calcinosis
    Emma M Johnstone
    University of Manchester, Manchester Academic Health Science Centre, Salford Royal Hospital, Salford, UK
    Rheumatology (Oxford) 51:2234-8. 2012
    ..Our aim was to investigate the hypothesis that acro-osteolysis is associated with (i) the severity of digital ischaemia and (ii) the presence of calcinosis...
  24. ncbi request reprint Systemic sclerosis: an update for clinicians
    Ariane L Herrick
    Rheumatic Diseases Centre, Clinical Sciences Building, University of Manchester, Salford Royal NHS Foundation Trust, Salford M6 8HD
    Br J Hosp Med (Lond) 69:464-70. 2008
    ..This review will discuss diagnosis, subtyping, and the major clinical features and their management...
  25. doi request reprint Incidence of childhood linear scleroderma and systemic sclerosis in the UK and Ireland
    Ariane L Herrick
    University of Manchester, Manchester, UK, and Salford Royal Hospital, Salford, UK
    Arthritis Care Res (Hoboken) 62:213-8. 2010
    ..Our aim was to ascertain the incidence of childhood scleroderma in its different forms in the UK and Ireland, and to describe the age, sex, and ethnicity of the cases...
  26. ncbi request reprint Comparison of thermography and laser Doppler imaging in the assessment of Raynaud's phenomenon
    Stuart Clark
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, M6 8HD, Salford, UK
    Microvasc Res 66:73-6. 2003
    ..Therefore one technique cannot substitute for another...
  27. ncbi request reprint Possible therapeutic use of vasodilator iontophoresis
    Andrea K Murray
    Department of Physics and Astronomy, Laser Photonics Group, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
    Microvasc Res 69:89-94. 2005
    ..The current treatment of choice for scleroderma-related critical digital ischaemia and/or ulceration is intravenous prostanoid therapy, necessitating hospitalisation. However, iloprost is often poorly tolerated and may be ineffective...
  28. ncbi request reprint Comparison of red and green laser doppler imaging of blood flow
    Andrea K Murray
    Laser Photonics Group, University of Manchester, Manchester M13 9PL, United Kingdom
    Lasers Surg Med 35:191-200. 2004
    ..Laser Doppler imaging (LDI) of perfusion has been performed with a novel green wavelength (532 nm) for comparison with a HeNe laser (633 nm), the aim being validation of the green laser wavelength as a research tool...
  29. ncbi request reprint Vascular imaging
    Ariane L Herrick
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Best Pract Res Clin Rheumatol 18:957-79. 2004
    ..For each of these, the method(s) and then the clinical and research applications are discussed. Laser Doppler, a research technique, is also described...
  30. ncbi request reprint Laser Doppler imaging: a developing technique for application in the rheumatic diseases
    A K Murray
    University of Manchester, Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 43:1210-8. 2004
  31. ncbi request reprint Nailfold video capillaroscopy in psoriasis
    M Bhushan
    Dermatology Centre and Centre for Rheumatic Diseases, University of Manchester, Hope Hospital, Salford, Manchester M6 8HD, U K
    Br J Dermatol 142:1171-6. 2000
    ..However, in contrast to previous studies, we found no specific pattern of a morphological nature of nailfold capillaries in patients with psoriasis with or without nail changes, when compared with normal controls...
  32. ncbi request reprint Calcium channel blockers for primary Raynaud's phenomenon
    Holly Ennis
    Centre for Musculoskeletal Research, Institute of Inflammation and Repair, University of Manchester, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, Manchester, UK, M13 9PT
    Cochrane Database Syst Rev 1:CD002069. 2014
    ..Primary Raynaud's phenomenon is a common condition characterised by an exaggerated vasospastic response to cold or emotion: classically the digits (fingers and toes) turn white, then blue, then red...
  33. doi request reprint The pathogenesis, diagnosis and treatment of Raynaud phenomenon
    Ariane L Herrick
    University of Manchester, Manchester Academic Health Science Centre, Salford Royal Hospital, Salford M6 8HD, UK
    Nat Rev Rheumatol 8:469-79. 2012
    ..This Review provides an update of the pathogenesis, diagnosis and treatment of Raynaud phenomenon. Current and future treatment approaches are discussed, and some key unanswered questions are highlighted...
  34. ncbi request reprint Computerized nailfold video capillaroscopy--a new tool for assessment of Raynaud's phenomenon
    Marina E Anderson
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    J Rheumatol 32:841-8. 2005
    ..To develop a computer based nailfold video capillaroscopy system with enhanced image quality and to assess its disease-subgroup resolving power in patients with primary and secondary Raynaud's phenomenon (RP)...
  35. ncbi request reprint Vasodilator iontophoresis a possible new therapy for digital ischaemia in systemic sclerosis?
    A K Murray
    Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Rheumatology (Oxford) 47:76-9. 2008
    ..This study investigated whether whole finger vasodilator iontophoresis increases digital blood flow in patients with systemic sclerosis (SSc): If so, this might indicate a novel approach to therapy...
  36. ncbi request reprint Digital vascular response to topical glyceryl trinitrate, as measured by laser Doppler imaging, in primary Raynaud's phenomenon and systemic sclerosis
    M E Anderson
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Rheumatology (Oxford) 41:324-8. 2002
    ..To investigate digital microvascular responses to topical glyceryl trinitrate (GTN) in patients with primary Raynaud's phenomenon (PRP), limited cutaneous systemic sclerosis (LCSSc) and healthy control subjects, using laser Doppler imaging...
  37. ncbi request reprint Lack of agreement between rheumatologists in defining digital ulceration in systemic sclerosis
    Ariane L Herrick
    University of Manchester, Manchester, UK, and Salford Royal National Health Service Foundation Trust, Salford, UK
    Arthritis Rheum 60:878-82. 2009
    ..To test the intra- and interobserver variability, among clinicians with an interest in systemic sclerosis (SSc), in defining digital ulcers...
  38. ncbi request reprint Occurrence of Raynaud's phenomenon in children ages 12-15 years: prevalence and association with other common symptoms
    Gareth T Jones
    University of Manchester, Manchester, UK
    Arthritis Rheum 48:3518-21. 2003
    ..This study was undertaken to ascertain the prevalence of RP in children ages 12-15 years and to determine whether, as with other commonly reported symptoms, there were any associations with adverse psychosocial factors...
  39. ncbi request reprint Dual wavelength (532 and 633 nm) laser Doppler imaging of plaque psoriasis
    A K Murray
    Laser Photonics Group, Department of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK
    Br J Dermatol 152:1182-6. 2005
    ..Increased blood flow occurs in plaques of psoriasis, and an increase in blood flow has been shown to occur in uninvolved skin adjacent to the active edge...
  40. ncbi request reprint Abnormal microvascular response is localized to the digits in patients with systemic sclerosis
    A K Murray
    Hope Hospital, Salford, UK
    Arthritis Rheum 54:1952-60. 2006
    ....
  41. pmc Assessing periarticular bone mineral density in patients with early psoriatic arthritis or rheumatoid arthritis
    B J Harrison
    Department of Rheumatology, North Manchester General Hospital and ARC Epidemiology Unit, University of Manchester, UK
    Ann Rheum Dis 61:1007-11. 2002
    ..Bone mineral density (BMD) can now be measured accurately using dual energy x ray absorptiometry (DEXA). Recently, DEXA has been used to measure periarticular BMD at predefined regions of interest (ROIs) around the joints...
  42. ncbi request reprint Malnutrition in systemic sclerosis
    Elizabeth Harrison
    Department of Gastroenterology, Salford Royal NHS Foundation Trust, Salford, UK
    Rheumatology (Oxford) 51:1747-56. 2012
    ..The development of specialist knowledge of SSc-related gastrointestinal disease management and nutritional screening and interventions is required. This paper reviews current knowledge relating to malnutrition and its management in SSc...
  43. ncbi request reprint Cigarette smoking as a significant risk factor for digital vascular disease in patients with systemic sclerosis
    Beverley J Harrison
    North Manchester General Hospital and ARC Epidemiology Unit, Manchester, UK
    Arthritis Rheum 46:3312-6. 2002
    ..Cigarette smoking is an important risk factor for vascular disease in the general population. We investigated the influence of cigarette smoking on digital ischemia in patients with SSc...
  44. ncbi request reprint Systemic sclerosis: patients' perceptions of their condition
    Helen L Richards
    Department of Behavioural Medicine, Hope Hospital, Salford, United Kingdom
    Arthritis Rheum 49:689-96. 2003
    ..To examine patients' beliefs about systemic sclerosis (SSc) and to investigate the relationship between these beliefs, symptom report, and clinical and demographic variables...
  45. ncbi request reprint The differential expression of VEGF, VEGFR-2, and GLUT-1 proteins in disease subtypes of systemic sclerosis
    Christine Ann Davies
    Division of Laboratory and Regenerative Medicine, University of Manchester, UK
    Hum Pathol 37:190-7. 2006
    ..Increased GLUT-1 expression in lcSSc/cal and dcSSc indicates that hypoxia is an associated factor...
  46. ncbi request reprint Home parenteral nutrition--an effective and safe long-term therapy for systemic sclerosis-related intestinal failure
    M Brown
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, Manchester, UK
    Rheumatology (Oxford) 47:176-9. 2008
    ....
  47. ncbi request reprint Expression of osteonectin and matrix Gla protein in scleroderma patients with and without calcinosis
    C A Davies
    Rheumatic Diseases Centre, Clinical Sciences Building, Hope Hospital, Eccles Old Road, Salford M6 8HD, UK
    Rheumatology (Oxford) 45:1349-55. 2006
    ....
  48. doi request reprint An investigation into the blood-flow characteristics of telangiectatic skin lesions in systemic sclerosis using dual-wavelength laser Doppler imaging
    A K Murray
    Rheumatic Diseases Centre, Hope Hospital, University of Manchester, Manchester, UK
    Clin Exp Dermatol 34:618-20. 2009
    ..Dual-wavelength LDI may help predict treatment response...
  49. ncbi request reprint Keloidal scleroderma
    T C Ling
    The Dermatology Centre, Hope Hospital, Manchester, UK
    Clin Exp Dermatol 28:171-3. 2003
    ..The nodules failed to respond to therapy with topical steroid, calcipotriol, or extended photochemotherapy. This is a rare, disfiguring variant of scleroderma, unresponsive to treatment, and poorly understood...
  50. ncbi request reprint A pilot study of acetic acid iontophoresis and ultrasound in the treatment of systemic sclerosis-related calcinosis
    S Shetty
    University of Manchester Rheumatic Diseases Centre, Salford, Leeds, UK
    Rheumatology (Oxford) 44:536-8. 2005
    ..This combination treatment has been used in other calcifying disorders...
  51. doi request reprint Pilot study of dual-wavelength (532 and 633 nm) laser Doppler imaging and infrared thermography of morphoea
    T L Moore
    Rheumatic Diseases Centre, University of Manchester, Salford Royal NHS Foundation Trust, Salford, UK
    Br J Dermatol 160:864-7. 2009
    ..Little is known about the pathophysiology of localized scleroderma (skin fibrosis, also termed 'morphoea'), although it is likely that microvascular dysfunction is a contributing factor...
  52. ncbi request reprint Seventeen-point dermal ultrasound scoring system--a reliable measure of skin thickness in patients with systemic sclerosis
    T L Moore
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 42:1559-63. 2003
    ..Our objective was to develop a 17-site ultrasound method of measuring skin thickness in patients with systemic sclerosis (SSc) and to assess its inter- and intra-observer variability...
  53. ncbi request reprint Antibodies against oxidized low-density lipoproteins in systemic sclerosis
    A L Herrick
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK
    Rheumatology (Oxford) 40:401-5. 2001
    ..Prospective longitudinal studies are required to investigate whether anti-oxidized LDL antibodies may be a marker of vascular damage in SSC...
  54. ncbi request reprint Ankle brachial pressure index in systemic sclerosis: influence of disease subtype and anticentromere antibody
    M C Wan
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Rheumatology (Oxford) 40:1102-5. 2001
    ..04 (95% CI -0.01 to +0.09). CONCLUSIONS: The severity of large vessel macrovascular disease, as assessed by ABPI, is not dependent on disease subtype. Anticentromere antibody may be weakly associated with a reduction in ABPI...
  55. ncbi request reprint Foot problems in patients with systemic sclerosis
    H Sari-Kouzel
    University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford M6 8HD, UK
    Rheumatology (Oxford) 40:410-3. 2001
    ..Care of the feet is therefore an important part of the management of SSC...
  56. pmc Development of a provisional core set of response measures for clinical trials of systemic sclerosis
    D Khanna
    Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, California 90095, USA
    Ann Rheum Dis 67:703-9. 2008
    ..To develop a provisional core set of response measures for clinical trials of systemic sclerosis (SSc)...
  57. ncbi request reprint A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma
    Rachel K Hoyles
    Royal Brompton Hospital, Imperial College, London, UK
    Arthritis Rheum 54:3962-70. 2006
    ..This RCT was undertaken to investigate the effects of intravenous (IV) cyclophosphamide (CYC) followed by azathioprine (AZA) treatment in pulmonary fibrosis in SSc...
  58. ncbi request reprint Polymorphisms in COL15 gene are not associated with systemic sclerosis
    Sudeep P Pushpakom
    National Genetics Reference Laboratory, Department of Medical Genetics, St Mary s Hospital, Hathersage Road, Manchester M13 0JH, UK
    J Rheumatol 35:251-3. 2008
    ..We undertook an association study to explore the role of COL15 single-nucleotide polymorphisms (SNP) in SSc disease development...
  59. pmc Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
    Gillian Rice
    Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, LS9 7TF, UK
    Am J Hum Genet 80:811-5. 2007
    ..Additionally, we describe a de novo heterozygous mutation, affecting a critical catalytic residue in TREX1, that results in typical Aicardi-Goutieres syndrome...