Carl Heneghan

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Optimal loading dose for the initiation of warfarin: a systematic review
    Carl Heneghan
    Department of Primary Health Care, University of Oxford, Oxford, UK
    BMC Cardiovasc Disord 10:18. 2010
  2. pmc Determining which automatic digital blood pressure device performs adequately: a systematic review
    Y Wan
    Department of Health Statistics, Fourth Military Medical University, Xi an, China
    J Hum Hypertens 24:431-8. 2010
  3. ncbi request reprint Prevention of hepatitis C in Japan: a lesson for us all
    Carl Heneghan
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF, UK
    Lancet 370:1982-3. 2007
  4. pmc Assessing differential attrition in clinical trials: self-monitoring of oral anticoagulation and type II diabetes
    Carl Heneghan
    Department of Primary Health Care, University of Oxford, Oxford, UK
    BMC Med Res Methodol 7:18. 2007
  5. ncbi request reprint Self-monitoring of oral anticoagulation: a systematic review and meta-analysis
    C Heneghan
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, UK
    Lancet 367:404-11. 2006
  6. pmc Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherence
    Carl Heneghan
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford
    Br J Gen Pract 57:948-52. 2007
  7. doi request reprint Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data
    Carl Heneghan
    Oxford University, Department of Primary Care Health Sciences, Oxford, UK
    Lancet 379:322-34. 2012
  8. pmc Primary care clinicians' attitudes towards point-of-care blood testing: a systematic review of qualitative studies
    Caroline H D Jones
    Department of Primary Care Health Sciences, University of Oxford, UK
    BMC Fam Pract 14:117. 2013
  9. pmc Assessment of central haemomodynamics from a brachial cuff in a community setting
    David Nunan
    Department of Primary Care Health Sciences, University of Oxford, Hythe Bridge St, Oxford, UK
    BMC Cardiovasc Disord 12:48. 2012
  10. pmc What are the basic self-monitoring components for cardiovascular risk management?
    Alison M Ward
    Department of Primary Health Care, The University of Oxford, Headington, UK
    BMC Med Res Methodol 10:105. 2010

Collaborators

Detail Information

Publications48

  1. pmc Optimal loading dose for the initiation of warfarin: a systematic review
    Carl Heneghan
    Department of Primary Health Care, University of Oxford, Oxford, UK
    BMC Cardiovasc Disord 10:18. 2010
    ..Selection of the right warfarin dose at the outset of treatment is not straightforward, and current evidence is lacking to determine the optimal strategy for initiation of therapy...
  2. pmc Determining which automatic digital blood pressure device performs adequately: a systematic review
    Y Wan
    Department of Health Statistics, Fourth Military Medical University, Xi an, China
    J Hum Hypertens 24:431-8. 2010
    ..Multiple readings are essential to provide clinicians and patients with accurate information on which to base diagnostic and treatment decisions...
  3. ncbi request reprint Prevention of hepatitis C in Japan: a lesson for us all
    Carl Heneghan
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF, UK
    Lancet 370:1982-3. 2007
  4. pmc Assessing differential attrition in clinical trials: self-monitoring of oral anticoagulation and type II diabetes
    Carl Heneghan
    Department of Primary Health Care, University of Oxford, Oxford, UK
    BMC Med Res Methodol 7:18. 2007
    ..Analyzing drop out rates and when they occur may give important information about the patient characteristics and trial characteristics that affect the overall uptake of an intervention...
  5. ncbi request reprint Self-monitoring of oral anticoagulation: a systematic review and meta-analysis
    C Heneghan
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, UK
    Lancet 367:404-11. 2006
    ..We did a systematic review and meta-analysis of all randomised controlled trials that assessed the effects of self-monitoring or self-management (self-testing and self-dosage) of anticoagulation compared with standard monitoring...
  6. pmc Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherence
    Carl Heneghan
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford
    Br J Gen Pract 57:948-52. 2007
    ..GPs vary greatly in their clinical management of hypertension, for reasons that are poorly understood...
  7. doi request reprint Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data
    Carl Heneghan
    Oxford University, Department of Primary Care Health Sciences, Oxford, UK
    Lancet 379:322-34. 2012
    ....
  8. pmc Primary care clinicians' attitudes towards point-of-care blood testing: a systematic review of qualitative studies
    Caroline H D Jones
    Department of Primary Care Health Sciences, University of Oxford, UK
    BMC Fam Pract 14:117. 2013
    ..We aimed to systematically review qualitative studies of primary care clinicians' attitudes to point-of-care blood tests...
  9. pmc Assessment of central haemomodynamics from a brachial cuff in a community setting
    David Nunan
    Department of Primary Care Health Sciences, University of Oxford, Hythe Bridge St, Oxford, UK
    BMC Cardiovasc Disord 12:48. 2012
    ..However, the feasibility of this method in a community based setting has not been assessed...
  10. pmc What are the basic self-monitoring components for cardiovascular risk management?
    Alison M Ward
    Department of Primary Health Care, The University of Oxford, Headington, UK
    BMC Med Res Methodol 10:105. 2010
    ..We examined the interventions included in systematic reviews of self-monitoring for four clinical problems that increase cardiovascular disease risk...
  11. pmc Physical activity for the prevention and treatment of major chronic disease: an overview of systematic reviews
    David Nunan
    Department Primary Care Health Sciences, Radcliffe Observatory Quarter, University of Oxford, Oxford OX2 6GG, UK
    Syst Rev 2:56. 2013
    ..This protocol has been registered on PROSPERO 2013: CRD42013003523...
  12. doi request reprint Increase in emergency admissions to hospital for children aged under 15 in England, 1999-2010: national database analysis
    Peter J Gill
    Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK
    Arch Dis Child 98:328-34. 2013
    ..To investigate a reported rise in the emergency hospital admission of children in England for conditions usually managed in the community...
  13. pmc Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysis
    Claire Friedemann
    University of Oxford, Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Oxford OX2 6GG, UK
    BMJ 345:e4759. 2012
    ..To describe the association and its magnitude between body mass index category, sex, and cardiovascular disease risk parameters in school aged children in highly developed countries...
  14. pmc Are treatments more effective than placebos? A systematic review and meta-analysis
    Jeremy Howick
    Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 8:e62599. 2013
    ..Whether such use is justified depends in part on the relative benefit of placebos compared to 'active' treatments. A direct test for differences between placebo and 'active' treatment effects has not been conducted...
  15. doi request reprint Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studies
    Alison M Ward
    Department of Primary Care Health Sciences, The University of Oxford, Oxford, UK
    J Hypertens 30:449-56. 2012
    ..Examine the relationship between home blood pressure (BP) and risk for all-cause mortality, cardiovascular mortality and cardiovascular events...
  16. doi request reprint A model for reflection for good clinical practice
    John I Balla
    Centre for Evidence Based Medicine, Department of Primary Care, Old Road Campus, Headington Oxford OX3 7LF, UK
    J Eval Clin Pract 15:964-9. 2009
    ..In line with good practice, the model also links the crucial knowledge used in decision making, to value judgments made in relation to the patient...
  17. ncbi request reprint Individual patient meta-analysis of self-monitoring of an oral anticoagulation protocol
    Rafael Perera
    Department of Primary Health Care, University of Oxford, UK
    J Heart Valve Dis 17:233-8. 2008
    ..In order to overcome these limitations and allow further investigation of the data, the study aim is to undertake an Individual Patient Data (IPD) meta-analysis...
  18. pmc Reducing antibiotic prescribing for children with respiratory tract infections in primary care: a systematic review
    Talley A Vodicka
    Department of Primary Care Health Sciences, University of Oxford, Oxford
    Br J Gen Pract 63:e445-54. 2013
    ..Respiratory tract infections (RTIs) in children are common and often result in antibiotic prescription despite their typically self-limiting course...
  19. pmc Intranasal corticosteroids in management of acute sinusitis: a systematic review and meta-analysis
    Gail Hayward
    Department of Primary Care Health Sciences, Oxford University, Oxford, England, UK
    Ann Fam Med 10:241-9. 2012
    ..We performed a systematic review and meta-analysis of the effects of intranasal corticosteroids on the symptoms of acute sinusitis...
  20. pmc Type and accuracy of sphygmomanometers in primary care: a cross-sectional observational study
    Christine A'court
    Department of Primary Health Care, University of Oxford, Oxford
    Br J Gen Pract 61:e598-603. 2011
    ..Previous studies identified worrying levels of sphygmomanometer inaccuracy and have not been repeated in the era of digital measurement of blood pressure...
  21. pmc Point-of-care testing for the analysis of lipid panels: primary care diagnostic technology update
    Annette Plüddemann
    Centre for Monitoring and Diagnosis, University of Oxford, Oxford, UK
    Br J Gen Pract 62:224-6. 2012
    ..Clinical Question Does point-of-care testing (POCT) for lipids improve the risk stratification and management of cardiovascular disease compared to standard practice...
  22. doi request reprint Individual patient data meta-analysis of trials of self-monitoring of blood glucose in non-insulin treated type 2 diabetes: protocol for a systematic review
    A J Farmer
    Department of Primary Health Care, NIHR School of Primary Care Research, University of Oxford, Oxford, UK
    Prim Care Diabetes 3:117-21. 2009
    ..We will systematically examine these factors within the trials of SMBG to enable further investigation of the data through an individual patient data analysis (IPD)...
  23. pmc The need for randomization in animal trials: an overview of systematic reviews
    Jennifer A Hirst
    Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 9:e98856. 2014
    ..We extended the scope the work from CAMARADES to include investigations of treatments for any condition...
  24. pmc Primary care diagnostic technology update: point-of-care testing for glycosylated haemoglobin
    Annette Plüddemann
    Primary Care Diagnostic Horizon Scanning, Centre for Monitoring and Diagnosis Oxford, Department of Primary Health Care, University of Oxford, Oxford, UK
    Br J Gen Pract 61:139-40. 2011
    ..In the monitoring of patients with type 1 and type 2 diabetes, what advantages does point-of-care HbA(1c) testing provide over current practice?..
  25. pmc Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: a systematic review of observational studies
    Susannah Fleming
    Oxford University, Department of Primary Health Care, Rosemary Rue Building, Old Road Campus, Headington, Oxford, UK
    Lancet 377:1011-8. 2011
    ..We aimed to derive new centile charts for these vital signs and to compare these centiles with existing international ranges...
  26. pmc What is missing from descriptions of treatment in trials and reviews?
    Paul Glasziou
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
    BMJ 336:1472-4. 2008
  27. doi request reprint Evidence-based medicine teaching in UK medical schools
    Emma Meats
    Department of Primary Health Care, University of Oxford, Oxford, UK
    Med Teach 31:332-7. 2009
    ..It is recognized that clinicians need training in evidence-based medicine (EBM), however there is considerable variation in the content and methods of the EBM curriculum in UK medical schools...
  28. pmc Placebo use in the United kingdom: results from a national survey of primary care practitioners
    Jeremy Howick
    Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 8:e58247. 2013
    ..Surveys in various countries suggest 17% to 80% of doctors prescribe 'placebos' in routine practice, but prevalence of placebo use in UK primary care is unknown...
  29. pmc Effect of UK policy on medical migration: a time series analysis of physician registration data
    Claire Blacklock
    Department of Primary Care Health Sciences, Oxford University, Radcliffe Observatory Quarter, Oxford, OX2 6GG, UK
    Hum Resour Health 10:35. 2012
    ..abstract:..
  30. pmc Prioritisation criteria for the selection of new diagnostic technologies for evaluation
    Annette Plüddemann
    Oxford Centre for Monitoring and Diagnosis, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF, UK
    BMC Health Serv Res 10:109. 2010
    ..Therefore we aimed to develop prioritisation criteria for the assessment of new diagnostic technologies, by gaining international consensus on not only which criteria should be used, but also their relative importance...
  31. pmc A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome
    Nourieh Hoveyda
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Old Road Campus, Headington, Oxford, UK
    BMC Gastroenterol 9:15. 2009
    ..We searched Ovid versions of MEDLINE (1950-2007), EMBASE (1980-2007), CINAHL (1982-2007), AMED (1985-2007), the Cochrane library and hand searched retrieved papers...
  32. pmc Corticosteroids for pain relief in sore throat: systematic review and meta-analysis
    Gail Hayward
    Department of Primary Health Care, University of Oxford, Bond University, Gold Coast, Queensland 4229, Australia
    BMJ 339:b2976. 2009
    ..To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children...
  33. doi request reprint Meta-analysis of individual patient data in randomised trials of self monitoring of blood glucose in people with non-insulin treated type 2 diabetes
    Andrew J Farmer
    Department of Primary Health Care, University of Oxford, and NIHR School for Primary Care Research, Oxford OX1 2ET, UK
    BMJ 344:e486. 2012
    ..To assess the effectiveness of self monitoring blood glucose levels in people with non-insulin treated type 2 diabetes compared with clinical management without self monitoring, and to explore the effects in specific patient groups...
  34. pmc The evidence base for interventions delivered to children in primary care: an overview of cochrane systematic reviews
    Peter J Gill
    Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
    PLoS ONE 6:e23051. 2011
    ....
  35. doi request reprint Adequacy of reporting monitoring regimens of risk factors for cardiovascular disease in clinical guidelines: systematic review
    Ivan Moschetti
    Department of Primary Health Care, University of Oxford, Oxford, UK
    BMJ 342:d1289. 2011
    ..To assess the reporting of monitoring recommendations in guidelines on the prevention and treatment of cardiovascular disease...
  36. pmc Using the Turning Research Into Practice (TRIP) database: how do clinicians really search?
    Emma Meats
    Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, United Kingdom
    J Med Libr Assoc 95:156-63. 2007
    ..This study aimed to examine clinicians' current search behavior when using the Turning Research Into Practice (TRIP) database to examine search engine use and the ways it might be improved...
  37. pmc Overview of systematic reviews: yoga as a therapeutic intervention for adults with acute and chronic health conditions
    Marcy C McCall
    Department of Continuing Education, Kellogg College, University of Oxford, 60 62 Banbury Road, Oxford OX2 6PN, UK
    Evid Based Complement Alternat Med 2013:945895. 2013
    ..Significant heterogeneity and variability in reporting interventions by type of yoga, settings, and population characteristics limit the generalizability of results...
  38. ncbi request reprint Accuracy of ambulatory blood pressure monitors: a systematic review of validation studies
    James A Hodgkinson
    Primary Care Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    J Hypertens 31:239-50. 2013
    ..Recent research and guidelines recommend the routine use of ambulatory blood pressure monitoring for the diagnosis of hypertension, so accuracy of such monitors is more important than ever...
  39. pmc Clinical decision making in a high-risk primary care environment: a qualitative study in the UK
    John Balla
    Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
    BMJ Open 2:e000414. 2012
    ..Examine clinical reasoning and decision making in an out of hours (OOH) primary care setting to gain insights into how general practitioners (GPs) make clinical decisions and manage risk in this environment...
  40. doi request reprint Interpreting meta-analysis in systematic reviews
    Rafael Perera
    Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
    Evid Based Med 13:67-9. 2008
  41. doi request reprint Epley and the slow boat from research to practice
    Paul Glasziou
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford, UK
    Evid Based Med 13:34-5. 2008
  42. doi request reprint Sex-specific familial clustering of myocardial infarction in patients with acute coronary syndromes
    Amitava Banerjee
    Stroke Prevention Research Unit, University of Oxford, Oxford, United Kingdom
    Circ Cardiovasc Genet 2:98-105. 2009
    ..Although excess mother-to-daughter "transmission" occurs in ischemic stroke, no published studies have considered sex-of-parent/sex-of-proband interactions in the heritability of MI...
  43. pmc Graphical method for depicting randomised trials of complex interventions
    Rafael Perera
    Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
    BMJ 334:127-9. 2007
  44. ncbi request reprint Making sense of diagnostic test likelihood ratios
    Raphael Perera
    University of Oxford, Oxford, England, UK
    ACP J Club 146:A8-9. 2007
  45. ncbi request reprint The GATE frame: critical appraisal with pictures
    Rod Jackson
    University of Auckland, Auckland, New Zealand
    Evid Based Med 11:35-8. 2006
  46. pmc Prevention of diabetes
    Carl Heneghan
    BMJ 333:764-5. 2006
  47. ncbi request reprint The GATE frame: critical appraisal with pictures
    Rod Jackson
    University of Auckland, Auckland, New Zealand
    ACP J Club 144:A8-11. 2006