Research Topics
| Carl HeneghanSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Optimal loading dose for the initiation of warfarin: a systematic reviewCarl Heneghan
Department of Primary Health Care, University of Oxford, Oxford, UK
BMC Cardiovasc Disord 10:18. 2010..Selection of the right warfarin dose at the outset of treatment is not straightforward, and current evidence is lacking to determine the optimal strategy for initiation of therapy...
Self-monitoring of oral anticoagulation: a systematic review and meta-analysisC Heneghan
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, UK
Lancet 367:404-11. 2006..We did a systematic review and meta-analysis of all randomised controlled trials that assessed the effects of self-monitoring or self-management (self-testing and self-dosage) of anticoagulation compared with standard monitoring...- Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherenceCarl Heneghan
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford
Br J Gen Pract 57:948-52. 2007..GPs vary greatly in their clinical management of hypertension, for reasons that are poorly understood... - Prevention of hepatitis C in Japan: a lesson for us allCarl Heneghan
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF, UK
Lancet 370:1982-3. 2007 - Assessing differential attrition in clinical trials: self-monitoring of oral anticoagulation and type II diabetesCarl Heneghan
Department of Primary Health Care, University of Oxford, Oxford, UK
BMC Med Res Methodol 7:18. 2007..Analyzing drop out rates and when they occur may give important information about the patient characteristics and trial characteristics that affect the overall uptake of an intervention... 
Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient dataCarl Heneghan
Oxford University, Department of Primary Care Health Sciences, Oxford, UK
Lancet 379:322-34. 2012....- Assessment of central haemomodynamics from a brachial cuff in a community settingDavid Nunan
Department of Primary Care Health Sciences, University of Oxford, Hythe Bridge St, Oxford, UK
BMC Cardiovasc Disord 12:48. 2012..However, the feasibility of this method in a community based setting has not been assessed... - What are the basic self-monitoring components for cardiovascular risk management?Alison M Ward
Department of Primary Health Care, The University of Oxford, Headington, UK
BMC Med Res Methodol 10:105. 2010..We examined the interventions included in systematic reviews of self-monitoring for four clinical problems that increase cardiovascular disease risk... - Cardiovascular disease risk in healthy children and its association with body mass index: systematic review and meta-analysisClaire Friedemann
University of Oxford, Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Oxford OX2 6GG, UK
BMJ 345:e4759. 2012..To describe the association and its magnitude between body mass index category, sex, and cardiovascular disease risk parameters in school aged children in highly developed countries... - Home measurement of blood pressure and cardiovascular disease: systematic review and meta-analysis of prospective studiesAlison M Ward
Department of Primary Care Health Sciences, The University of Oxford, Oxford, UK
J Hypertens 30:449-56. 2012..Examine the relationship between home blood pressure (BP) and risk for all-cause mortality, cardiovascular mortality and cardiovascular events... - A model for reflection for good clinical practiceJohn I Balla
Centre for Evidence Based Medicine, Department of Primary Care, Old Road Campus, Headington Oxford OX3 7LF, UK
J Eval Clin Pract 15:964-9. 2009..In line with good practice, the model also links the crucial knowledge used in decision making, to value judgments made in relation to the patient... - Individual patient meta-analysis of self-monitoring of an oral anticoagulation protocolRafael Perera
Department of Primary Health Care, University of Oxford, UK
J Heart Valve Dis 17:233-8. 2008..In order to overcome these limitations and allow further investigation of the data, the study aim is to undertake an Individual Patient Data (IPD) meta-analysis... - Intranasal corticosteroids in management of acute sinusitis: a systematic review and meta-analysisGail Hayward
Department of Primary Care Health Sciences, Oxford University, Oxford, England, UK
Ann Fam Med 10:241-9. 2012..We performed a systematic review and meta-analysis of the effects of intranasal corticosteroids on the symptoms of acute sinusitis... - Type and accuracy of sphygmomanometers in primary care: a cross-sectional observational studyChristine A'court
Department of Primary Health Care, University of Oxford, Oxford
Br J Gen Pract 61:e598-603. 2011..Previous studies identified worrying levels of sphygmomanometer inaccuracy and have not been repeated in the era of digital measurement of blood pressure... - Point-of-care testing for the analysis of lipid panels: primary care diagnostic technology updateAnnette Plüddemann
Centre for Monitoring and Diagnosis, University of Oxford, Oxford, UK
Br J Gen Pract 62:224-6. 2012..Clinical Question Does point-of-care testing (POCT) for lipids improve the risk stratification and management of cardiovascular disease compared to standard practice... - Individual patient data meta-analysis of trials of self-monitoring of blood glucose in non-insulin treated type 2 diabetes: protocol for a systematic reviewA J Farmer
Department of Primary Health Care, NIHR School of Primary Care Research, University of Oxford, Oxford, UK
Prim Care Diabetes 3:117-21. 2009..We will systematically examine these factors within the trials of SMBG to enable further investigation of the data through an individual patient data analysis (IPD)... - Increase in emergency admissions to hospital for children aged under 15 in England, 1999-2010: national database analysisPeter J Gill
Department of Primary Care Health Sciences, University of Oxford, Radcliffe Observatory Quarter, Woodstock Road, Oxford OX2 6GG, UK
Arch Dis Child 98:328-34. 2013..To investigate a reported rise in the emergency hospital admission of children in England for conditions usually managed in the community... - Evidence-based medicine teaching in UK medical schoolsEmma Meats
Department of Primary Health Care, University of Oxford, Oxford, UK
Med Teach 31:332-7. 2009..It is recognized that clinicians need training in evidence-based medicine (EBM), however there is considerable variation in the content and methods of the EBM curriculum in UK medical schools... - What is missing from descriptions of treatment in trials and reviews?Paul Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 336:1472-4. 2008 - Normal ranges of heart rate and respiratory rate in children from birth to 18 years of age: a systematic review of observational studiesSusannah Fleming
Oxford University, Department of Primary Health Care, Rosemary Rue Building, Old Road Campus, Headington, Oxford, UK
Lancet 377:1011-8. 2011..We aimed to derive new centile charts for these vital signs and to compare these centiles with existing international ranges... - Primary care diagnostic technology update: point-of-care testing for glycosylated haemoglobinAnnette Plüddemann
Primary Care Diagnostic Horizon Scanning, Centre for Monitoring and Diagnosis Oxford, Department of Primary Health Care, University of Oxford, Oxford, UK
Br J Gen Pract 61:139-40. 2011..CLINICAL QUESTION: In the monitoring of patients with type 1 and type 2 diabetes, what advantages does point-of-care HbA(1c) testing provide over current practice?.. - A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndromeNourieh Hoveyda
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Old Road Campus, Headington, Oxford, UK
BMC Gastroenterol 9:15. 2009..We searched Ovid versions of MEDLINE (1950-2007), EMBASE (1980-2007), CINAHL (1982-2007), AMED (1985-2007), the Cochrane library and hand searched retrieved papers... - Prioritisation criteria for the selection of new diagnostic technologies for evaluationAnnette Plüddemann
Oxford Centre for Monitoring and Diagnosis, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF, UK
BMC Health Serv Res 10:109. 2010..Therefore we aimed to develop prioritisation criteria for the assessment of new diagnostic technologies, by gaining international consensus on not only which criteria should be used, but also their relative importance... - Effect of UK policy on medical migration: a time series analysis of physician registration dataClaire Blacklock
Department of Primary Care Health Sciences, Oxford University, Radcliffe Observatory Quarter, Oxford, OX2 6GG, UK
Hum Resour Health 10:35. 2012..abstract:.. - Corticosteroids for pain relief in sore throat: systematic review and meta-analysisGail Hayward
Department of Primary Health Care, University of Oxford, Bond University, Gold Coast, Queensland 4229, Australia
BMJ 339:b2976. 2009..To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children... - Meta-analysis of individual patient data in randomised trials of self monitoring of blood glucose in people with non-insulin treated type 2 diabetesAndrew J Farmer
Department of Primary Health Care, University of Oxford, and NIHR School for Primary Care Research, Oxford OX1 2ET, UK
BMJ 344:e486. 2012..To assess the effectiveness of self monitoring blood glucose levels in people with non-insulin treated type 2 diabetes compared with clinical management without self monitoring, and to explore the effects in specific patient groups... - Adequacy of reporting monitoring regimens of risk factors for cardiovascular disease in clinical guidelines: systematic reviewIvan Moschetti
Department of Primary Health Care, University of Oxford, Oxford, UK
BMJ 342:d1289. 2011..To assess the reporting of monitoring recommendations in guidelines on the prevention and treatment of cardiovascular disease... - The evidence base for interventions delivered to children in primary care: an overview of cochrane systematic reviewsPeter J Gill
Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
PLoS ONE 6:e23051. 2011.... - Using the Turning Research Into Practice (TRIP) database: how do clinicians really search?Emma Meats
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, United Kingdom
J Med Libr Assoc 95:156-63. 2007..This study aimed to examine clinicians' current search behavior when using the Turning Research Into Practice (TRIP) database to examine search engine use and the ways it might be improved... - Placebo use in the United kingdom: results from a national survey of primary care practitionersJeremy Howick
Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom
PLoS ONE 8:e58247. 2013..Surveys in various countries suggest 17% to 80% of doctors prescribe 'placebos' in routine practice, but prevalence of placebo use in UK primary care is unknown... - Accuracy of ambulatory blood pressure monitors: a systematic review of validation studiesJames A Hodgkinson
Primary Care Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, UK
J Hypertens 31:239-50. 2013..Recent research and guidelines recommend the routine use of ambulatory blood pressure monitoring for the diagnosis of hypertension, so accuracy of such monitors is more important than ever... - Clinical decision making in a high-risk primary care environment: a qualitative study in the UKJohn Balla
Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
BMJ Open 2:e000414. 2012..Examine clinical reasoning and decision making in an out of hours (OOH) primary care setting to gain insights into how general practitioners (GPs) make clinical decisions and manage risk in this environment... - Epley and the slow boat from research to practicePaul Glasziou
Centre for Evidence-based Medicine, Department of Primary Health Care, University of Oxford, Oxford, UK
Evid Based Med 13:34-5. 2008 - Interpreting meta-analysis in systematic reviewsRafael Perera
Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
Evid Based Med 13:67-9. 2008 - Sex-specific familial clustering of myocardial infarction in patients with acute coronary syndromesAmitava Banerjee
Stroke Prevention Research Unit, University of Oxford, Oxford, United Kingdom
Circ Cardiovasc Genet 2:98-105. 2009..Although excess mother-to-daughter "transmission" occurs in ischemic stroke, no published studies have considered sex-of-parent/sex-of-proband interactions in the heritability of MI... - Graphical method for depicting randomised trials of complex interventionsRafael Perera
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 334:127-9. 2007 - Making sense of diagnostic test likelihood ratiosRaphael Perera
University of Oxford, Oxford, England, UK
ACP J Club 146:A8-9. 2007 - Prevention of diabetesCarl Heneghan
BMJ 333:764-5. 2006 - The GATE frame: critical appraisal with picturesRod Jackson
University of Auckland, Auckland, New Zealand
Evid Based Med 11:35-8. 2006 - The GATE frame: critical appraisal with picturesRod Jackson
University of Auckland, Auckland, New Zealand
ACP J Club 144:A8-11. 2006