Neil C Henderson

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Integrin-mediated regulation of TGFβ in fibrosis
    Neil C Henderson
    MRC Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK Electronic address
    Biochim Biophys Acta 1832:891-6. 2013
  2. doi request reprint Hepatic fibrogenesis: from within and outwith
    Neil C Henderson
    The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Toxicology 254:130-5. 2008
  3. ncbi request reprint Regulation of alternative macrophage activation by galectin-3
    Alison C Mackinnon
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, 49 Little France Crescent, Edinburgh, United Kingdom
    J Immunol 180:2650-8. 2008
  4. pmc Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function
    Sarah L Farnworth
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK
    Am J Pathol 172:395-405. 2008
  5. doi request reprint The regulation of inflammation by galectin-3
    Neil C Henderson
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK
    Immunol Rev 230:160-71. 2009
  6. pmc Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
    Neil C Henderson
    1 Lung Biology Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA 2 Medical Research Council Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK
    Nat Med 19:1617-24. 2013
  7. pmc Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis
    Neil C Henderson
    The Queen s Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK
    Am J Pathol 172:288-98. 2008
  8. ncbi request reprint Liver fibrosis: cellular mechanisms of progression and resolution
    Neil C Henderson
    MRC University of Edinburgh Centre for Inflammation Research, Queen s Medical Research Institute, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4TJ, U K
    Clin Sci (Lond) 112:265-80. 2007
  9. doi request reprint Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
    John P Iredale
    MRC Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK Electronic address
    Biochim Biophys Acta 1832:876-83. 2013

Collaborators

Detail Information

Publications9

  1. pmc Integrin-mediated regulation of TGFβ in fibrosis
    Neil C Henderson
    MRC Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, 47 Little France Crescent, Edinburgh EH16 4TJ, UK Electronic address
    Biochim Biophys Acta 1832:891-6. 2013
    ..This article is part of a Special Issue entitled: Fibrosis: Translation of basic research to human disease...
  2. doi request reprint Hepatic fibrogenesis: from within and outwith
    Neil C Henderson
    The Queen s Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK
    Toxicology 254:130-5. 2008
    ..We will then discuss newly emerging sources of scar forming cells during hepatic injury together with the role of hepatic macrophages which have a regulatory function in both the formation and resolution of liver fibrosis...
  3. ncbi request reprint Regulation of alternative macrophage activation by galectin-3
    Alison C Mackinnon
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, 49 Little France Crescent, Edinburgh, United Kingdom
    J Immunol 180:2650-8. 2008
    ..Pharmacological modulation of galectin-3 function represents a novel therapeutic strategy in pathologies associated with alternatively activated macrophages...
  4. pmc Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function
    Sarah L Farnworth
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK
    Am J Pathol 172:395-405. 2008
    ....
  5. doi request reprint The regulation of inflammation by galectin-3
    Neil C Henderson
    Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK
    Immunol Rev 230:160-71. 2009
    ..In this review, we examine the role of galectin-3 in inflammation, and discuss the manipulation of galectin-3 expression as a potentially novel therapeutic strategy in the treatment of a broad range of inflammatory diseases...
  6. pmc Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
    Neil C Henderson
    1 Lung Biology Center, Department of Medicine, University of California, San Francisco, San Francisco, California, USA 2 Medical Research Council Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK
    Nat Med 19:1617-24. 2013
    ..These data identify a core pathway that regulates fibrosis and suggest that pharmacological targeting of all α(v) integrins may have clinical utility in the treatment of patients with a broad range of fibrotic diseases...
  7. pmc Galectin-3 expression and secretion links macrophages to the promotion of renal fibrosis
    Neil C Henderson
    The Queen s Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK
    Am J Pathol 172:288-98. 2008
    ..Therefore, we demonstrate for the first time that galectin-3 expression and secretion by macrophages is a major mechanism linking macrophages to the promotion of renal fibrosis...
  8. ncbi request reprint Liver fibrosis: cellular mechanisms of progression and resolution
    Neil C Henderson
    MRC University of Edinburgh Centre for Inflammation Research, Queen s Medical Research Institute, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4TJ, U K
    Clin Sci (Lond) 112:265-80. 2007
    ....
  9. doi request reprint Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
    John P Iredale
    MRC Centre for Inflammation Research, The Queen s Medical Research Institute, University of Edinburgh, Edinburgh, UK Electronic address
    Biochim Biophys Acta 1832:876-83. 2013
    ..This article is part of a Special Issue entitled: Fibrosis: Translation of basic research to human disease...