Research Topics
| Jeremy C HebdenSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Accuracy and resolution of THz reflection spectroscopy for medical imagingCaroline B Reid
Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK
Phys Med Biol 55:4825-38. 2010..The accuracy and resolution of each method were determined to assess the potential of each method as a tool for medical diagnosis at THz frequencies...
Optical tomography of the neonatal brainJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London, WC1E 6BT, UK
Eur Radiol 17:2926-33. 2007..Optical tomography of the healthy infant brain is also providing a means of studying neurophysiological processes during early development and the potential consequences of prematurity...
Assessment of an in situ temporal calibration method for time-resolved optical tomographyJeremy C Hebden
University College London, Department of Medical Physics and Bioengineering, 11 20 Capper Street, London WC1E 6JA, UK
J Biomed Opt 8:87-92. 2003..The effectiveness of the method is briefly demonstrated by imaging a solid object with tissue-equivalent optical properties...
Monitoring recovery after laser surgery of the breast with optical tomography: a case studyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, United Kingdom
Appl Opt 44:1898-904. 2005..Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed...
Advances in optical imaging of the newborn infant brainJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, 11 20 Capper Street, London WC1E 6JA, UK
Psychophysiology 40:501-10. 2003..Recent technological and methodological advances in this research field are reviewed, and the likely impact of optical imaging methods on the care of newborn infants is assessed...
Experimental evaluation of an anisotropic scattering model of a slab geometryJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, London WC1E 6JA, UK
Opt Lett 29:2518-20. 2004..It is shown that a single set of optical parameters is sufficient to model the experimental measurements acquired across all three orientations of the cube...
Three-dimensional time-resolved optical mammography of the uncompressed breastLouise C Enfield
Department of Medical Physics and Bioengineering, University College London, London, WC1E 6BT, UK
Appl Opt 46:3628-38. 2007..Only half of the fibroadenomas scanned could be observed, but of those that could be detected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation...
Imaging changes in blood volume and oxygenation in the newborn infant brain using three-dimensional optical tomographyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, 11-20 Capper Street, London WC1E 6JA, UK
Phys Med Biol 49:1117-30. 2004..The results exhibit large changes in absorption coefficient at both wavelengths. Images corresponding to differences in concentrations of oxy- and deoxyhaemoglobin are in qualitative agreement with known physiological data...
A quantitative assessment of the depth sensitivity of an optical topography system using a solid dynamic tissue-phantomTeresa Correia
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 54:6277-86. 2009....
Optical tomography of the breast using a multi-channel time-resolved imagerTara Yates
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 50:2503-17. 2005..Drawbacks of our current methodology and plans for overcoming them are discussed...
Linear and nonlinear reconstruction for optical tomography of phantoms with nonscattering regionsAdam P Gibson
Department of Medical Physics and Bioengineering, University College London, London WC1E 6JA, United Kingdom
Appl Opt 44:3925-36. 2005..This study supports the use of linear reconstruction for dynamic imaging but suggests that, in all cases, image quality is likely to improve if the clear regions are modeled correctly...
Three-dimensional optical tomography of the premature infant brainJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, 11-20 Capper Street, London WC1E 6JA, UK
Phys Med Biol 47:4155-66. 2002....
Time-resolved optical mammography using a liquid coupled interfaceTara D Yates
University College London, Department of Medical Physics and Bioengineering, London WC1E 6BT, United Kingdom
J Biomed Opt 10:054011. 2005..Preliminary images of a healthy human subject are also presented, which reveal subtle heterogeneity, particularly in the distribution of scatter. The ability to detect an absorbing target adjacent to the breast is also demonstrated...
Transient haemodynamic events in neurologically compromised infants: a simultaneous EEG and diffuse optical imaging studyR J Cooper
Biomedical Optics Research Laboratory, Department of Medical Physics and Bioengineering, University College London, London, UK
Neuroimage 55:1610-6. 2011..The importance and physiological implications of our findings are discussed, as is the suitability of a combined EEG and diffuse optical imaging approach to the study and monitoring of neonatal brain injury...
Optical tomography of a realistic neonatal head phantomAdam Gibson
Department of Medical Physics and Bioengineering, University College London, 11 20 Capper Street, London WC1E 6JA
Appl Opt 42:3109-16. 2003..The head-shaped mesh performed slightly better than the spherical mesh, particularly when the absorption of the central region of the phantom was increased...
Three-dimensional optical topography of brain activity in infants watching videos of human movementTeresa Correia
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 57:1135-46. 2012..These results suggest that infants a few months old have regions which are specialized for reacting to human activity, and that these subtle changes can be effectively analysed using 3D optical topography...
A tissue-like optically turbid and electrically conducting phantom for simultaneous EEG and near-infrared imagingR J Cooper
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 54:N403-8. 2009..The results of this simultaneous EEG and near-infrared imaging experiment are presented...
Design and evaluation of a probe for simultaneous EEG and near-infrared imaging of cortical activationR J Cooper
Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK
Phys Med Biol 54:2093-102. 2009..We successfully acquired NIR optical and EEG data simultaneously for both our phantom and our human motor cortex experiments, clearly demonstrating the effectiveness and suitability of our 'opto-electrode'...
A dynamic optical imaging phantom based on an array of semiconductor diodesJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 53:N407-13. 2008..Two designs of diode-array phantom are described and results of imaging experiments are presented...
An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systemsJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 53:329-37. 2008..Images of the phantom have been reconstructed using data acquired with a continuous wave optical topography system...
Optical tomography of breast cancer-monitoring response to primary medical therapyLouise C Enfield
Department of Medical Physics and Bioengineering, Malet Place Engineering Building, University College London, Gower Street, London, WC1E 6BT, UK
Target Oncol 4:219-33. 2009..These findings demonstrate that optical techniques could play a role in the monitoring of changes in angiogenesis, apoptosis and hypoxia due to neoadjuvant chemotherapy...
Mid-infrared optical coherence tomographyChristopher S Colley
Department of Medical Physics and Bioengineering, University College London, Malet Place Engineering Building, Gower Street, London WC1E 6BT, United Kingdom
Rev Sci Instrum 78:123108. 2007..Therefore, this technology provides an opportunity for optical coherence molecular imaging without the need for molecular contrast agents. Preliminary measurements are presented...
A soft deformable tissue-equivalent phantom for diffuse optical tomographyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 51:5581-90. 2006..The deformable phantoms may be used to test and calibrate optical tomography systems designed for use on patients with irregular or variable geometries...
Optical imaging of infants' neurocognitive development: recent advances and perspectivesYasuyo Minagawa-Kawai
Laboratoire de Sciences Cognitives et Psycholinguistique, EHESS DEC ENS CNRS, Paris 75005, France
Dev Neurobiol 68:712-28. 2008..Although NIRS studies of the infant brain have yet to fulfill their potential, a review of the work done so far indicates that NIRS is likely to provide many unique insights in the field of developmental neuroscience...
Comparison between a time-domain and a frequency-domain system for optical tomographyIlkka Nissila
Helsinki University of Technology, Laboratory of Biomedical Engineering, 02015 HUT, Finland
J Biomed Opt 11:064015. 2006..The image quality of the reconstructions from the data measured with the two systems were compared with several quantitative criteria. In general a higher contrast was observed in the images calculated from the HUT data...
Validity conditions for the radiative transfer equationLuis Martí-López
Centro de Neurociencias de Cuba, Apartado Postal 6412, C P 10600, La Habana, Cuba
J Opt Soc Am A Opt Image Sci Vis 20:2046-56. 2003..Each condition is geometrically interpreted. Some implications of the results are discussed...
