David C Harrowven

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi request reprint Total synthesis of cavicularin and riccardin C: addressing the synthesis of an arene that adopts a boat configuration
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK
    Angew Chem Int Ed Engl 44:3899-901. 2005
  2. ncbi request reprint An Efficient Flow-Photochemical Synthesis of 5H-Furanones Leads to an Understanding of Torquoselectivity in Cyclobutenone Rearrangements
    David C Harrowven
    Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ UK
    Angew Chem Int Ed Engl 51:4405-8. 2012
  3. doi request reprint Potassium carbonate-silica: a highly effective stationary phase for the chromatographic removal of organotin impurities
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK
    Chem Commun (Camb) 46:6335-7. 2010
  4. doi request reprint CH activation and CH2 double activation of indolines by radical translocation: understanding the chemistry of the indolinyl radical
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, Hampshire, UK
    Org Biomol Chem 9:4882-5. 2011
  5. doi request reprint Macrocylic bisbibenzyl natural products and their chemical synthesis
    David C Harrowven
    Chemistry, University of Southampton, Southampton, SO17 1BJ, UK
    Nat Prod Rep 29:223-42. 2012
  6. doi request reprint New insights into cyclobutenone rearrangements: a total synthesis of the natural ROS-generating anti-cancer agent cribrostatin 6
    Mubina Mohamed
    Chemistry, University of Southampton, Highfield, Southampton, Hampshire, SO17 1BJ, UK
    Chemistry 17:13698-705. 2011
  7. doi request reprint Unified syntheses of cavicularin and riccardin C: addressing the synthesis of an arene adopting a boat configuration
    Sarah L Kostiuk
    Chemistry, University of Southampton, Highfield, Southampton, Hampshire, SO17 1BJ, UK
    Chemistry 17:10906-15. 2011
  8. ncbi request reprint Total synthesis of (-)-colombiasin A and (-)-elisapterosin B
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, UK
    Angew Chem Int Ed Engl 44:1221-2. 2005

Collaborators

  • DENNIS CURRAN
  • Sarah L Kostiuk
  • Mubina Mohamed
  • Peter D Howes
  • Richard J Whitby
  • Helen F Sneddon
  • Timothy Woodcock
  • Leo F Dudin
  • Théo P Gonçalves

Detail Information

Publications8

  1. ncbi request reprint Total synthesis of cavicularin and riccardin C: addressing the synthesis of an arene that adopts a boat configuration
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK
    Angew Chem Int Ed Engl 44:3899-901. 2005
  2. ncbi request reprint An Efficient Flow-Photochemical Synthesis of 5H-Furanones Leads to an Understanding of Torquoselectivity in Cyclobutenone Rearrangements
    David C Harrowven
    Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ UK
    Angew Chem Int Ed Engl 51:4405-8. 2012
    ..Selectivity in the photochemical rearrangement is due a dichotomous reactivity of the (E)- and (Z)-vinylketene intermediates...
  3. doi request reprint Potassium carbonate-silica: a highly effective stationary phase for the chromatographic removal of organotin impurities
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK
    Chem Commun (Camb) 46:6335-7. 2010
    ..Organotin impurities in product mixtures can be reduced from stoichiometric levels to approximately 15 parts per million by column chromatography using 10% w/w anhydrous potassium carbonate-silica as a stationary phase...
  4. doi request reprint CH activation and CH2 double activation of indolines by radical translocation: understanding the chemistry of the indolinyl radical
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton, Hampshire, UK
    Org Biomol Chem 9:4882-5. 2011
    ..The fate of the C2 indolinyl radical is dictated by the substitution at C3. Fragmentation, cyclisation and tandem cyclisation reactions leading to indole, azaheterocycle and azapropellane formation, respectively, are reported...
  5. doi request reprint Macrocylic bisbibenzyl natural products and their chemical synthesis
    David C Harrowven
    Chemistry, University of Southampton, Southampton, SO17 1BJ, UK
    Nat Prod Rep 29:223-42. 2012
    ..Prod. Rep. 1995, 12, 69-75) and largely focuses on new additions to the family and the strategies used to effect their chemical synthesis...
  6. doi request reprint New insights into cyclobutenone rearrangements: a total synthesis of the natural ROS-generating anti-cancer agent cribrostatin 6
    Mubina Mohamed
    Chemistry, University of Southampton, Highfield, Southampton, Hampshire, SO17 1BJ, UK
    Chemistry 17:13698-705. 2011
    ..A short and efficient total synthesis of cribrostatin 6, an anti-neoplastic and anti-microbial agent, provides a topical demonstration of the value of this method...
  7. doi request reprint Unified syntheses of cavicularin and riccardin C: addressing the synthesis of an arene adopting a boat configuration
    Sarah L Kostiuk
    Chemistry, University of Southampton, Highfield, Southampton, Hampshire, SO17 1BJ, UK
    Chemistry 17:10906-15. 2011
    ....
  8. ncbi request reprint Total synthesis of (-)-colombiasin A and (-)-elisapterosin B
    David C Harrowven
    School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, UK
    Angew Chem Int Ed Engl 44:1221-2. 2005