Catherine J Harmer

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Sustained attention deficit in bipolar disorder is not a working memory impairment in disguise
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Neuropsychologia 40:1586-90. 2002
  2. doi request reprint Effect of acute antidepressant administration on negative affective bias in depressed patients
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Am J Psychiatry 166:1178-84. 2009
  3. doi request reprint Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression
    Zola N Mannie
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Br J Psychiatry 192:356-61. 2008
  4. doi request reprint Short-term antidepressant treatment modulates amygdala response to happy faces
    Ray Norbury
    Psychopharmacology Research Unit PPRU, Department of Psychiatry, University of Oxford, Warneford Hospital, Neurosciences Building, Headington, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 206:197-204. 2009
  5. ncbi request reprint Impaired emotional categorisation in young people at increased familial risk of depression
    Zola N Mannie
    University Department of Psychiatry, Neurosciences Building, Warneford Hospital, Oxford OX3 7JX, UK
    Neuropsychologia 45:2975-80. 2007
  6. ncbi request reprint Differential effects of erythropoietin on neural and cognitive measures of executive function 3 and 7 days post-administration
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
    Exp Brain Res 184:313-21. 2008
  7. doi request reprint Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers
    Jamie Horder
    University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
    Psychopharmacology (Berl) 205:85-91. 2009
  8. ncbi request reprint Effects of alpha-lactalbumin on emotional processing in healthy women
    Helen Scrutton
    University Department of Psychiatry, Warneford Hospital, Oxford UK
    J Psychopharmacol 21:519-24. 2007
  9. doi request reprint Risk for depression and neural responses to fearful facial expressions of emotion
    Stella W Y Chan
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    Br J Psychiatry 194:139-45. 2009
  10. ncbi request reprint Lack of effect of tyrosine depletion on mood in recovered depressed women
    Sarah F B McTavish
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Neuropsychopharmacology 30:786-91. 2005

Detail Information

Publications59

  1. ncbi request reprint Sustained attention deficit in bipolar disorder is not a working memory impairment in disguise
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Neuropsychologia 40:1586-90. 2002
    ..Deficits in sustaining attention may help explain the difficulties in psychological and occupational functioning in bipolar disorder patients during remission...
  2. doi request reprint Effect of acute antidepressant administration on negative affective bias in depressed patients
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Am J Psychiatry 166:1178-84. 2009
    ..The authors investigated whether this effect is apparent in depressed patients early in treatment, prior to changes in mood and symptoms...
  3. doi request reprint Affective modulation of anterior cingulate cortex in young people at increased familial risk of depression
    Zola N Mannie
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Br J Psychiatry 192:356-61. 2008
    ..We previously found that children of parents with depression showed impaired performance on a task of emotional categorisation...
  4. doi request reprint Short-term antidepressant treatment modulates amygdala response to happy faces
    Ray Norbury
    Psychopharmacology Research Unit PPRU, Department of Psychiatry, University of Oxford, Warneford Hospital, Neurosciences Building, Headington, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 206:197-204. 2009
    ..These early effects of antidepressants may be an important component in the therapeutic effects of antidepressant treatment in patients with depression and anxiety...
  5. ncbi request reprint Impaired emotional categorisation in young people at increased familial risk of depression
    Zola N Mannie
    University Department of Psychiatry, Neurosciences Building, Warneford Hospital, Oxford OX3 7JX, UK
    Neuropsychologia 45:2975-80. 2007
    ..However, impairment in emotional categorization could identify a high-risk phenotype and may indicate that people at genetic risk of depression have difficulty in using "mood as information"...
  6. ncbi request reprint Differential effects of erythropoietin on neural and cognitive measures of executive function 3 and 7 days post-administration
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
    Exp Brain Res 184:313-21. 2008
    ..The present study supports the notion that Epo may have clinical applications in the treatment of psychiatric disorder characterized by cognitive dysfunction...
  7. doi request reprint Acute administration of the cannabinoid CB1 antagonist rimonabant impairs positive affective memory in healthy volunteers
    Jamie Horder
    University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
    Psychopharmacology (Berl) 205:85-91. 2009
    ..The anti-obesity drug and cannabinoid type 1 receptor antagonist, rimonabant, is associated with significant rates of depression and anxiety in clinical use...
  8. ncbi request reprint Effects of alpha-lactalbumin on emotional processing in healthy women
    Helen Scrutton
    University Department of Psychiatry, Warneford Hospital, Oxford UK
    J Psychopharmacol 21:519-24. 2007
    ..Further studies in subjects more vulnerable to stress are needed to assess the potential therapeutic effects of alpha-lactalbumin in clinical populations...
  9. doi request reprint Risk for depression and neural responses to fearful facial expressions of emotion
    Stella W Y Chan
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    Br J Psychiatry 194:139-45. 2009
    ..Depression is associated with neural abnormalities in emotional processing...
  10. ncbi request reprint Lack of effect of tyrosine depletion on mood in recovered depressed women
    Sarah F B McTavish
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Neuropsychopharmacology 30:786-91. 2005
    ..However ratings of depression were unaffected, suggesting that disruption of dopaminergic function by this manipulation does not induce a lowering of mood in individuals vulnerable to depression...
  11. doi request reprint Frontolimbic responses to emotional faces in young people at familial risk of depression
    Zola N Mannie
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    J Affect Disord 130:127-32. 2011
    ..The aim of the present study was to examine whether related neural abnormalities might be present in young people at increased familial risk of depression but with no personal history of illness...
  12. doi request reprint Risk for depression is associated with neural biases in emotional categorisation
    Stella W Y Chan
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
    Neuropsychologia 46:2896-903. 2008
    ..These results highlight a role of the fronto-parietal circuitry in emotional processing and further suggest that negative biases in these neural processes may be involved in risk for depression...
  13. doi request reprint Short-term serotonergic but not noradrenergic antidepressant administration reduces attentional vigilance to threat in healthy volunteers
    Susannah E Murphy
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Int J Neuropsychopharmacol 12:169-79. 2009
    ..Future studies are needed to clarify the neural mechanisms through which these effects on threat processing are mediated...
  14. ncbi request reprint Erythropoietin improves mood and modulates the cognitive and neural processing of emotion 3 days post administration
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    Neuropsychopharmacology 33:611-8. 2008
    ..Consistent with our previous finding, Epo improved self-reported mood for all 3 days post-administration. Together, these results suggest that characterization of the effects of Epo in a clinically depressed group is warranted...
  15. ncbi request reprint Emotional bias and waking salivary cortisol in relatives of patients with major depression
    Marisa Le Masurier
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Psychol Med 37:403-10. 2007
    ..We also measured waking salivary cortisol, as the regulation of the hypothalamo-pituitary-adrenal (HPA) axis is thought to be impaired in depressive disorder...
  16. doi request reprint A single dose of mirtazapine modulates neural responses to emotional faces in healthy people
    Nancy B Rawlings
    Psychopharmacology and Emotion Research Laboratory, Department of Psychiatry, University of Oxford, Warneford Hospital, Neurosciences Building, Headington, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 212:625-34. 2010
    ..The aim of this study was to investigate the effect of a single dose of mirtazapine on the neural processing of emotional faces in healthy volunteers...
  17. ncbi request reprint Low-dose tryptophan depletion in recovered depressed patients induces changes in cognitive processing without depressive symptoms
    Gail Hayward
    University Department of Psychiatry, Warneford Hospital, Oxford OX1 3UD, UK
    Biol Psychiatry 57:517-24. 2005
    ..The neurochemical mechanism is thought to be impairment of brain serotonin neurotransmission, but the neuropsychologic mechanisms underlying the effect are unclear...
  18. doi request reprint Short-term NK1 receptor antagonism and emotional processing in healthy volunteers
    Abbie Pringle
    Department of Psychiatry, University of Oxford, Oxford, UK
    Psychopharmacology (Berl) 215:239-46. 2011
    ..Healthy volunteer models of emotional processing offer a potential means by which novel drugs can be screened prior to clinical trials. Here, we consider the effect of 7 days of treatment with aprepitant in such a model...
  19. doi request reprint Neural responses to emotional faces in women recovered from anorexia nervosa
    Felicity A Cowdrey
    University of Oxford, Department of Psychiatry, Oxford, UK
    Psychiatry Res 201:190-5. 2012
    ..These results suggest that processing of emotional faces may not be aberrant after recovery from anorexia nervosa...
  20. doi request reprint Agomelatine facilitates positive versus negative affective processing in healthy volunteer models
    Catherine J Harmer
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    J Psychopharmacol 25:1159-67. 2011
    ..The study highlights the potential value of volunteer models in drug development for screening and profiling of novel antidepressants...
  21. doi request reprint Effects of 7 days of treatment with the cannabinoid type 1 receptor antagonist, rimonabant, on emotional processing
    Jamie Horder
    University Department of Psychiatry, Neurosciences Building, Warneford Hospital, Oxford, UK
    J Psychopharmacol 26:125-32. 2012
    ..Investigating such effects could be useful in detecting adverse psychiatric effects of novel treatments...
  22. pmc The D2 antagonist sulpiride modulates the neural processing of both rewarding and aversive stimuli in healthy volunteers
    Ciara McCabe
    Neuroscience Building, Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 217:271-8. 2011
    ..We have developed a functional magnetic resonance imaging (fMRI) model which permits examination of the neural processing of both rewarding and aversive stimuli...
  23. ncbi request reprint Increased positive versus negative affective perception and memory in healthy volunteers following selective serotonin and norepinephrine reuptake inhibition
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Am J Psychiatry 161:1256-63. 2004
    ..The present study therefore assessed the actions of repeated antidepressant administration on perception and memory for positive and negative emotional information in healthy volunteers...
  24. pmc Lateral prefrontal cortex mediates the cognitive modification of attentional bias
    Michael Browning
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 67:919-25. 2010
    ..It has been hypothesized, but not proved, that psychological interventions may alter the function of prefrontal regions supervising the allocation of attentional resources...
  25. doi request reprint NK1 receptor antagonism and the neural processing of emotional information in healthy volunteers
    Ciara McCabe
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Int J Neuropsychopharmacol 12:1261-74. 2009
    ..Such findings confirm animal studies which support a role for NK1 receptors in emotion. Such an approach may be useful in understanding the effects of novel drug treatments prior to full-scale clinical trials...
  26. pmc A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression
    Zola N Mannie
    Psychopharmacology Research Unit, University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, United Kingdom
    Biol Psychiatry 67:471-7. 2010
    ..These abnormalities apparently persist into clinical remission, raising the possibility that they might be trait markers indicating vulnerability to depression...
  27. ncbi request reprint Antidepressant drug treatment modifies the neural processing of nonconscious threat cues
    Catherine J Harmer
    Department of Experimental Psychology, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 59:816-20. 2006
    ..Emotional disorders such as depression and anxiety have been associated with hyperactivity of the amygdala, but it is unknown whether antidepressant treatment directly affects amygdala responses to emotionally significant information...
  28. ncbi request reprint 5HT(3) antagonism abolishes the emotion potentiated startle effect in humans
    Catherine J Harmer
    Department of Experimental Psychology, University of Oxford, and University Department of Psychiatry, Warneford Hospital, Oxford, OX1 3UD, UK
    Psychopharmacology (Berl) 186:18-24. 2006
    ..The serotonergic system has been implicated in emotional processing in animals and humans. Although the contribution of different receptor subtypes has been hypothesised, there have been few direct tests of this in human subjects...
  29. pmc 'It's the way that you look at it'--a cognitive neuropsychological account of SSRI action in depression
    Catherine J Harmer
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
    Philos Trans R Soc Lond B Biol Sci 368:20120407. 2013
    ..This suggests intriguing links between the effect of SSRIs to promote synaptic plasticity and neurogenesis, and their ability to remediate negative emotional biases in depressed patients...
  30. ncbi request reprint Tryptophan supplementation induces a positive bias in the processing of emotional material in healthy female volunteers
    Susannah E Murphy
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 187:121-30. 2006
    ..However, evidence of its efficacy as the primary treatment for depression is limited, and the direct action of TRP on the symptoms of depression and anxiety has not been well-characterised...
  31. doi request reprint Low-dose tryptophan depletion in recovered depressed women induces impairments in autobiographical memory specificity
    Anneke D M Haddad
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
    Psychopharmacology (Berl) 207:499-508. 2009
    ....
  32. doi request reprint The common adolescent bipolar phenotype shows positive biases in emotional processing
    Philippa L Rock
    Department of Psychiatry, University of Oxford, Warneford Hospital, UK
    Bipolar Disord 12:606-15. 2010
    ..However, studies of euthymic bipolar disorder patients may be confounded by the experience of mood episodes and medication. We therefore assessed an adolescent group for vulnerability markers associated with the bipolar phenotype...
  33. ncbi request reprint Single dose antidepressant administration modulates the neural processing of self-referent personality trait words
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
    Neuroimage 37:904-11. 2007
    ..These results support the hypothesis that antidepressants have early effects on the neural processing of emotional material which may be important in their therapeutic actions...
  34. doi request reprint Why do antidepressants take so long to work? A cognitive neuropsychological model of antidepressant drug action
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Br J Psychiatry 195:102-8. 2009
    ..The neuropharmacological actions of antidepressants are well characterised but our understanding of how these changes translate into improved mood are still emerging...
  35. doi request reprint Neural processing of reward and punishment in young people at increased familial risk of depression
    Ciara McCabe
    Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom
    Biol Psychiatry 72:588-94. 2012
    ..The aim of the present study was to determine whether similar abnormalities might be present in young people at increased familial risk of depression but with no personal history of mood disorder...
  36. pmc Using an experimental medicine model to explore combination effects of pharmacological and cognitive interventions for depression and anxiety
    Michael Browning
    Department of Psychiatry, University of Oxford, Oxford, UK
    Neuropsychopharmacology 36:2689-97. 2011
    ..More generally, the findings suggest that pinpointing the cognitive actions of treatments may inform future development of combination strategies in mental health...
  37. doi request reprint Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers
    Jamie Horder
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Int J Neuropsychopharmacol 13:1103-13. 2010
    ..fMRI may be a useful method of screening novel agents for unwanted effects on reward and associated clinical adverse reactions...
  38. ncbi request reprint Normalization of enhanced fear recognition by acute SSRI treatment in subjects with a previous history of depression
    Zubin Bhagwagar
    University Department of Psychiatry, Warneford Hospital, Oxford
    Am J Psychiatry 161:166-8. 2004
    ....
  39. ncbi request reprint The role of the anterior cingulate cortex in the counting Stroop task
    Gail Hayward
    Department of Psychiatry, Oxford University, Oxford, UK
    Exp Brain Res 154:355-8. 2004
    ..The Stroop interference effect was abolished by TMS over both anterior cingulate sites. These findings support functional neuroimaging research which suggests that cingulate cortex is central to the processes underlying the Stroop task...
  40. ncbi request reprint Bilateral generic working memory circuit requires left-lateralized addition for verbal processing
    Manaan Kar Ray
    Oxfordshire and Buckinghamshire Partnership National Health Service Trust, Warneford Hospital, Warneford Lane, Oxford OX3 7JX, UK
    Cereb Cortex 18:1421-8. 2008
    ....
  41. ncbi request reprint Increased waking salivary cortisol levels in young people at familial risk of depression
    Zola N Mannie
    Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford OX3 7JX, UK
    Am J Psychiatry 164:617-21. 2007
    ..The present study sought to answer this question by measuring waking salivary cortisol levels in young people at familial risk of depression but with no personal history of mood disorder...
  42. pmc Expectancy and surprise predict neural and behavioral measures of attention to threatening stimuli
    Michael Browning
    Department of Psychiatry, Oxford University, Oxford, UK
    Neuroimage 59:1942-8. 2012
    ..These results suggest that continuously calculated estimates of the probability of threat may plausibly be used to influence the deployment of visual attention and that use of this information is perturbed in anxious individuals...
  43. doi request reprint Efficacy markers in depression
    Catherine J Harmer
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford OX3 7JX, UK
    J Psychopharmacol 25:1148-58. 2011
    ..Greater validation is required to assess whether these effects are an obligatory component of effective treatment of depression and whether use of these models can improve the accuracy of go/no-go decisions in drug development...
  44. pmc Neural representation of reward in recovered depressed patients
    Ciara McCabe
    University Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK
    Psychopharmacology (Berl) 205:667-77. 2009
    ..We hypothesized that people at risk of depression by virtue of a personal history of the illness would show impaired neural responses to a primary rewarding stimulus...
  45. doi request reprint Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa
    Felicity A Cowdrey
    Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 70:736-43. 2011
    ..We hypothesized that women recovered from anorexia nervosa would show aberrant neural responses to both rewarding and aversive disorder-relevant stimuli...
  46. ncbi request reprint Acute administration of citalopram facilitates memory consolidation in healthy volunteers
    Catherine J Harmer
    Neurosciences Building, University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Psychopharmacology (Berl) 163:106-10. 2002
    ..However, the improvement in cognitive function often found following successful pharmacological treatment in depression may be confounded by symptom improvement...
  47. doi request reprint Serotonin and emotional processing: does it help explain antidepressant drug action?
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Neuropharmacology 55:1023-8. 2008
    ..Antidepressants may not directly modulate mood and anxiety but rather allow a different perspective for our ongoing evaluation of our self, the world and the future...
  48. ncbi request reprint Short-term antidepressant treatment and facial processing. Functional magnetic resonance imaging study
    Ray Norbury
    University of Oxford Centre for Clinical Magnetic Resonance Research, MRS Unit, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Br J Psychiatry 190:531-2. 2007
    ..Our results show that reboxetine modulates the neural substrates of emotional processing, highlighting a mechanism by which drug treatment could normalise negative bias in depression and anxiety...
  49. doi request reprint Combined NK₁ antagonism and serotonin reuptake inhibition: effects on emotional processing in humans
    Catherine J Harmer
    Department of Psychiatry, University of Oxford, Oxford, UK
    J Psychopharmacol 27:435-43. 2013
    ..GSK424887 is a selective competitive antagonist of the human NK₁ receptor and inhibitor of the serotonin transporter. However, its actions in human models of depression have not been assessed...
  50. doi request reprint Emotional processing and antidepressant action
    Catherine J Harmer
    Warneford Hospital, University Department of Psychiatry, Headington, Oxford, OX3 7JX, UK
    Curr Top Behav Neurosci 14:209-22. 2013
    ..Such a model could be applied to improve treatment development, stratification and combination approaches for patients with depression and provide a framework for considering and overcoming treatment nonresponse...
  51. pmc Effects of short-term varenicline administration on emotional and cognitive processing in healthy, non-smoking adults: a randomized, double-blind, study
    Roel J T Mocking
    University Department of Psychiatry, Warneford Hospital, Oxford, UK
    Neuropsychopharmacology 38:476-84. 2013
    ..In contrast, varenicline may have cognitive-enhancing effects...
  52. ncbi request reprint Enhanced recognition of disgust in bipolar illness
    Catherine J Harmer
    University Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Biol Psychiatry 51:298-304. 2002
    ..Although impairments of cognitive function have been found to persist in bipolar patients during periods of euthymic mood, it is not known whether abnormalities in emotional processing also occur during these periods of recovery...
  53. doi request reprint Effects of pramipexole on the processing of rewarding and aversive taste stimuli
    Ciara McCabe
    Neuroscience Building, Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, OX3 7JX, UK
    Psychopharmacology (Berl) 228:283-90. 2013
    ..Investigation of single doses of pramipexole in healthy participants in reward-based learning tasks has shown inhibition of the neural processing of reward, presumptively through stimulation of dopamine autoreceptors...
  54. ncbi request reprint Enhanced early morning salivary cortisol in neuroticism
    Maria J Portella
    Department of Psychiatry, Warneford Hospital, Neurosciences Bldg, Oxford OX3 7JX, UK
    Am J Psychiatry 162:807-9. 2005
    ..This study compared waking cortisol levels in healthy subjects with high and low levels of neuroticism without a previous history of depression...
  55. ncbi request reprint A dose-finding study on the effects of branch chain amino acids on surrogate markers of brain dopamine function
    Harm J Gijsman
    University of Oxford, Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK
    Psychopharmacology (Berl) 160:192-7. 2002
    ..The amino acid mixture we tested previously is unpalatable, whereas mixtures containing only branch chain amino acids can be made more palatable. However, the effects of such mixtures on dopamine function in humans have not been studied...
  56. ncbi request reprint Highly neurotic never-depressed students have negative biases in information processing
    Stella W Y Chan
    Department of Experimental Psychology, University of Oxford, UK
    Psychol Med 37:1281-91. 2007
    ..Although negatively biased cognitions are well documented in depressed patients and to some extent in recovered patients, it remains unclear whether these abnormalities are present before the first depressive episode...
  57. ncbi request reprint Toward a neuropsychological theory of antidepressant drug action: increase in positive emotional bias after potentiation of norepinephrine activity
    Catherine J Harmer
    Department of Psychiatry, Oxford University, Warneford Hospital, Oxford OX3 7JX, USA
    Am J Psychiatry 160:990-2. 2003
    ..Cognitive theories suggest that biases in information processing lead depressed patients to make unrealistically negative judgments about themselves and the world...
  58. ncbi request reprint Erythropoietin enhances hippocampal response during memory retrieval in humans
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
    J Neurosci 27:2788-92. 2007
    ..04) independent of changes in hematocrit. This is consistent with upregulation of hippocampal BDNF and neurotrophic actions found in animals and highlights Epo as a promising candidate for treatment of psychiatric disorders...
  59. ncbi request reprint Erythropoietin reduces neural and cognitive processing of fear in human models of antidepressant drug action
    Kamilla Miskowiak
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, United Kingdom
    Biol Psychiatry 62:1244-50. 2007
    ..The current study aimed to explore the effects of Epo on neural and behavioral measures of emotional processing relevant for depression and the effects of conventional antidepressant medication...