Rowan S Hardy

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. pmc Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation
    Rowan S Hardy
    Bone Research Program, ANZAC Research Institute, University of Sydney, Hospital Road, Concord, Sydney, 2139, Australia
    Arthritis Res Ther 15:R24. 2013
  2. pmc Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis
    Rowan Hardy
    Arthritis Res Ther 14:R226. 2012
  3. doi request reprint Endogenous glucocorticoids in inflammation: contributions of systemic and local responses
    Rowan S Hardy
    Centre for Endocrinology, Diabetes and Metabolism, Institute of Biomedical Research, University of Birmingham, United Kingdom
    Swiss Med Wkly 142:w13650. 2012
  4. ncbi request reprint Glucocorticoid metabolism in rheumatoid arthritis
    Rowan S Hardy
    Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom
    Ann N Y Acad Sci 1318:18-26. 2014
  5. doi request reprint Targeting 11β-hydroxysteroid dehydrogenases: a novel approach to manipulating local glucocorticoid levels with implications for rheumatic disease
    Rowan S Hardy
    Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, B15 2TH, UK
    Curr Opin Pharmacol 13:440-4. 2013
  6. doi request reprint Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin
    Ana Tiganescu
    Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
    J Invest Dermatol 131:30-6. 2011

Collaborators

Detail Information

Publications6

  1. pmc Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation
    Rowan S Hardy
    Bone Research Program, ANZAC Research Institute, University of Sydney, Hospital Road, Concord, Sydney, 2139, Australia
    Arthritis Res Ther 15:R24. 2013
    ..Additionally, this study provides guidelines for the effective characterisation, duration and treatment of murine FLS culture...
  2. pmc Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis
    Rowan Hardy
    Arthritis Res Ther 14:R226. 2012
    ..Consequently, the links between synovial inflammation, altered Wnt signalling and bone remodelling are not direct but are dependent on local activation of endogenous glucocorticoids...
  3. doi request reprint Endogenous glucocorticoids in inflammation: contributions of systemic and local responses
    Rowan S Hardy
    Centre for Endocrinology, Diabetes and Metabolism, Institute of Biomedical Research, University of Birmingham, United Kingdom
    Swiss Med Wkly 142:w13650. 2012
    ..Increasingly, it will be important to understand how the levels of glucocorticoids within the circulation and within the tissues are regulated in a coordinated manner...
  4. ncbi request reprint Glucocorticoid metabolism in rheumatoid arthritis
    Rowan S Hardy
    Rheumatology Research Group, University of Birmingham, Birmingham, United Kingdom
    Ann N Y Acad Sci 1318:18-26. 2014
    ..The role of 11β-HSD enzymes in the severity and persistence of inflammatory arthritis in a clinical setting is currently being explored. ..
  5. doi request reprint Targeting 11β-hydroxysteroid dehydrogenases: a novel approach to manipulating local glucocorticoid levels with implications for rheumatic disease
    Rowan S Hardy
    Centre for Endocrinology, Diabetes and Metabolism, University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, B15 2TH, UK
    Curr Opin Pharmacol 13:440-4. 2013
    ....
  6. doi request reprint Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin
    Ana Tiganescu
    Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
    J Invest Dermatol 131:30-6. 2011
    ..The age- and site-associated increase in dermal 11β-HSD1, and the ensuing increased local GC activation, may contribute to the adverse changes in skin morphology and function associated with chronological aging and photoaging...