W Hamilton

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. ncbi request reprint Diagnosis of lung cancer in primary care: a structured review
    William Hamilton
    Division of Primary Health Care, Cotham House, Cotham Hill, Bristol BS6 6JL, UK
    Fam Pract 21:605-11. 2004
  2. pmc The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records
    S Stapley
    CAPER research practices, Halford Wing, Dean Clarke House, Exeter, UK
    Br J Cancer 95:1321-5. 2006
  3. pmc Pathways to the diagnosis of lung cancer in the UK: a cohort study
    Jacqueline Barrett
    CAPER research unit, Exeter EX4 5BW, UK
    BMC Fam Pract 9:31. 2008
  4. pmc Risk of ovarian cancer in women with symptoms in primary care: population based case-control study
    William Hamilton
    NIHR School for Primary Care Research, Department of Community Based Medicine, University of Bristol, Bristol BS8 2AA, UK
    BMJ 339:b2998. 2009
  5. pmc Five misconceptions in cancer diagnosis
    William Hamilton
    National School for Primary Care Research, Academic Unit of Primary Health Care, University of Bristol
    Br J Gen Pract 59:441-5, 447; discussion 446. 2009
  6. pmc Clinical features of prostate cancer before diagnosis: a population-based, case-control study
    William Hamilton
    Department of Community Based Medicine, University of Bristol, The Grange, 1 Woodland Road, Bristol BS8 1AU
    Br J Gen Pract 56:756-62. 2006
  7. ncbi request reprint The effect of patient self-completion agenda forms on prescribing and adherence in general practice: a randomized controlled trial
    William Hamilton
    CAPER research practices, Halford Wing Dean Clarke House, Southernhay, Exeter EX1 1PQ, UK
    Fam Pract 24:77-83. 2007
  8. pmc The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients
    W Hamilton
    Department of Community Based Medicine, NIHR School for Primary Care Research, University of Bristol, 25 27 Belgrave Road, Bristol, UK
    Br J Cancer 101:S80-6. 2009
  9. pmc Clinical features of primary brain tumours: a case-control study using electronic primary care records
    William Hamilton
    Academic Unit of Primary Health Care, University of Bristol, Bristol
    Br J Gen Pract 57:695-9. 2007
  10. pmc The importance of anaemia in diagnosing colorectal cancer: a case-control study using electronic primary care records
    W Hamilton
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, 25 Belgrave Road, Bristol BS8 2AA, UK
    Br J Cancer 98:323-7. 2008

Detail Information

Publications33

  1. ncbi request reprint Diagnosis of lung cancer in primary care: a structured review
    William Hamilton
    Division of Primary Health Care, Cotham House, Cotham Hill, Bristol BS6 6JL, UK
    Fam Pract 21:605-11. 2004
    ..This is partly addressed by referral guidelines which aim to help GPs in selection of patients for chest X-ray or referral for specialist investigation...
  2. pmc The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records
    S Stapley
    CAPER research practices, Halford Wing, Dean Clarke House, Exeter, UK
    Br J Cancer 95:1321-5. 2006
    ..5 (0.98, 2.3): P=0.064). When corrected for emergency admission, sex, and the site of the tumour, the HR for mild anaemia was 1.7 (1.1, 2.6); P=0.015. No relationship was found between the duration of symptoms and staging or mortality...
  3. pmc Pathways to the diagnosis of lung cancer in the UK: a cohort study
    Jacqueline Barrett
    CAPER research unit, Exeter EX4 5BW, UK
    BMC Fam Pract 9:31. 2008
    ..We performed a cohort study of 246 patients with lung cancer in Exeter, Devon UK. All patients had their cancer symptoms, referrals and diagnoses identified and dated using their doctors' records...
  4. pmc Risk of ovarian cancer in women with symptoms in primary care: population based case-control study
    William Hamilton
    NIHR School for Primary Care Research, Department of Community Based Medicine, University of Bristol, Bristol BS8 2AA, UK
    BMJ 339:b2998. 2009
    ..To identify and quantify symptoms of ovarian cancer in women in primary care...
  5. pmc Five misconceptions in cancer diagnosis
    William Hamilton
    National School for Primary Care Research, Academic Unit of Primary Health Care, University of Bristol
    Br J Gen Pract 59:441-5, 447; discussion 446. 2009
    ..Finally, considerable nihilism exists about the value of early diagnosis, despite considerable observational evidence that earlier diagnosis of symptomatic cancer is beneficial...
  6. pmc Clinical features of prostate cancer before diagnosis: a population-based, case-control study
    William Hamilton
    Department of Community Based Medicine, University of Bristol, The Grange, 1 Woodland Road, Bristol BS8 1AU
    Br J Gen Pract 56:756-62. 2006
    ..Even in areas where screening is available, many prostate cancers are diagnosed after the symptoms begin. However, the risk posed by particular symptoms is largely unknown, especially in unselected populations such as primary care...
  7. ncbi request reprint The effect of patient self-completion agenda forms on prescribing and adherence in general practice: a randomized controlled trial
    William Hamilton
    CAPER research practices, Halford Wing Dean Clarke House, Southernhay, Exeter EX1 1PQ, UK
    Fam Pract 24:77-83. 2007
    ..What the patient wants from a general practice consultation and what the doctor believes they want are not always the same thing. This mismatch may lead to unwanted and unnecessary prescribing...
  8. pmc The CAPER studies: five case-control studies aimed at identifying and quantifying the risk of cancer in symptomatic primary care patients
    W Hamilton
    Department of Community Based Medicine, NIHR School for Primary Care Research, University of Bristol, 25 27 Belgrave Road, Bristol, UK
    Br J Cancer 101:S80-6. 2009
    ..They also sought to quantify the risk of cancer for symptoms and primary care investigations, both individually and paired together...
  9. pmc Clinical features of primary brain tumours: a case-control study using electronic primary care records
    William Hamilton
    Academic Unit of Primary Health Care, University of Bristol, Bristol
    Br J Gen Pract 57:695-9. 2007
    ..Around 4500 new primary brain tumours are diagnosed in the UK each year. Symptoms of these tumours have not previously been studied in primary care...
  10. pmc The importance of anaemia in diagnosing colorectal cancer: a case-control study using electronic primary care records
    W Hamilton
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, 25 Belgrave Road, Bristol BS8 2AA, UK
    Br J Cancer 98:323-7. 2008
    ..7% (5.7, 11). Current guidance for urgent investigation of anaemia misses some patients with a moderate risk of cancer, particularly men...
  11. pmc What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study
    W Hamilton
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, Bristol BS8 1AU, UK
    Thorax 60:1059-65. 2005
    ..Over 38,000 new cases of lung cancer occur each year in the UK. Most are diagnosed after initial presentation to primary care, but the relative importance of the various clinical features is largely unknown...
  12. pmc Clinical features of colorectal cancer before diagnosis: a population-based case-control study
    W Hamilton
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, UK
    Br J Cancer 93:399-405. 2005
    ..1% (5.1, 10); blood glucose >10 mmol l(-1) 0.78% (0.51, 1.1): all P < 0.001. Earlier diagnosis of colorectal cancer may be possible using the predictive values for single or multiple symptoms, physical signs or test results...
  13. ncbi request reprint The prognosis of different fatigue diagnostic labels: a longitudinal survey
    William T Hamilton
    The Grange, Bristol BS8 1AU, UK
    Fam Pract 22:383-8. 2005
    ..An allied condition is fibromyalgia. No study has examined prognostic differences across these different labels...
  14. ncbi request reprint Diagnosis of colorectal cancer in primary care: the evidence base for guidelines
    William Hamilton
    Division of Primary Health Care, Cotham House, Cotham Hill, Bristol BS6 6JL, UK
    Fam Pract 21:99-106. 2004
    ..However, a GP would only expect to see one new presentation each year. Referral guidelines outlining clinical scenarios of high risk have been published. These aim to help GPs select patients for rapid investigation...
  15. pmc The risk of colorectal cancer with symptoms at different ages and between the sexes: a case-control study
    William Hamilton
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, 25 Belgrave Road, Bristol, BS8 2AA, UK
    BMC Med 7:17. 2009
    ..Although the presenting features of the cancer are well described, the risks they convey are less well known. This study aimed to quantify the risk of cancer for different symptoms, across age groups and in both sexes...
  16. ncbi request reprint High incidence of mesothelioma in an English city without heavy industrial use of asbestos
    William T Hamilton
    Division of Primary Health Care, University of Bristol
    J Public Health (Oxf) 26:77-8. 2004
    ..Lower rates have been reported from areas without such industries. We studied an area without heavy industry to examine if such a pattern occurred in England...
  17. pmc Symptomatic diagnosis of prostate cancer in primary care: a structured review
    William Hamilton
    Division of Primary Health Care, University of Bristol, Cotham House, Cotham Hill, Bristol BS6 6JL
    Br J Gen Pract 54:617-21. 2004
    ..A general practitioner (GP) has to try and identify which of these patients have prostate cancer...
  18. pmc Cancer diagnosis in primary care
    William Hamilton
    NIHR School for Primary Care Research, Department of Community Based Medicine, University of Bristol, Bristol
    Br J Gen Pract 60:121-8. 2010
    ..It concentrates on the four commonest UK cancers: breast, lung, colon, and prostate as these have been the subject of most recent studies...
  19. pmc The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case-control study using electronic records
    S Stapley
    School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, UK
    Br J Cancer 108:25-31. 2013
    ..Over 15 000 new oesophago-gastric cancers are diagnosed annually in the United Kingdom, with most being advanced disease. We identified and quantified features of this cancer in primary care...
  20. pmc Features of cancer in teenagers and young adults in primary care: a population-based nested case-control study
    R M Dommett
    School of Clinical Sciences, University of Bristol, Level 6 UHB Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
    Br J Cancer 108:2329-33. 2013
    ..Teenagers and young adults (TYA, 15-24 years) diagnosed with cancer report repeated visits to primary care before referral. We investigated associations of symptoms and consultation frequency in primary care with TYA cancers...
  21. pmc The risk of pancreatic cancer in symptomatic patients in primary care: a large case-control study using electronic records
    S Stapley
    School of Social and Community Medicine, University of Bristol, UK
    Br J Cancer 106:1940-4. 2012
    ..Over 8000 new pancreatic cancers are diagnosed annually in the UK; most at an advanced stage, with only 3% 5-year survival. We aimed to identify and quantify the risk of pancreatic cancer for features in primary care...
  22. ncbi request reprint Clinical features of colorectal cancer before emergency presentation: a population-based case-control study
    Jonathan Cleary
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol The Grange, 1 Woodland Road, Bristol BS8 1AU, UK
    Fam Pract 24:3-6. 2007
    ..To identify the clinical features of colorectal cancer presenting as a surgical emergency...
  23. ncbi request reprint What happens to new-onset headache in children that present to primary care? A case-cohort study using electronic primary care records
    D Kernick
    Primary Care Research Group, Peninsula College of Medicine and Dentistry, St Luke s Campus, University of Bristol, Bristol, UK
    Cephalalgia 29:1311-6. 2009
    ..General practitioners are likely to be underdiagnosing migraine. This study can inform management guidelines for new presentations of headache in primary care, particularly when a secondary pathology is suspected...
  24. doi request reprint Pathways to the diagnosis of ovarian cancer in the UK: a cohort study in primary care
    J Barrett
    CAPER research unit, Exeter, UK
    BJOG 117:610-4. 2010
    ..To identify the routes patients with ovarian cancer take between first symptom presentation and diagnosis...
  25. doi request reprint Ovarian cancer prediction: development of a scoring system for primary care
    K Grewal
    University Hospital Bristol, Bristol Royal Infirmary, Bristol, UK
    BJOG 120:1016-9. 2013
    ..Recent studies have identified specific symptoms of ovarian cancer at all stages, raising the hope of reducing diagnostic delays. We aimed to devise a scoring system for symptoms of ovarian cancer in primary care...
  26. pmc Features of childhood cancer in primary care: a population-based nested case-control study
    R M Dommett
    School of Clinical Sciences, University of Bristol, Level 6 UHB Education Centre, Upper Maudlin Street, Bristol BS2 8AE, UK
    Br J Cancer 106:982-7. 2012
    ..This study investigated the risk of cancer in children with alert symptoms identified in current UK guidance, or with increased consultation frequency in primary care...
  27. ncbi request reprint Pathways to the diagnosis of colorectal cancer: an observational study in three UK cities
    Jacqueline Barrett
    Academic Unit of Primary Health Care, Department of Community Based Medicine, University of Bristol, The Grange, 1 Woodland Road, Bristol BS8 1AU, UK
    Fam Pract 23:15-9. 2006
    ..The route that has received most investment in the UK National Health Service is the 2-week clinic, but the proportions of patients taking this and other routes to diagnosis are largely unknown...
  28. doi request reprint What happens to new-onset headache presented to primary care? A case-cohort study using electronic primary care records
    D Kernick
    St Thomas Medical Group, Exeter, UK
    Cephalalgia 28:1188-95. 2008
    ..Accepting the limitations of this approach, our data can inform management guidelines for new presentations of headache in primary care and confirm the need for follow-up, even if a primary headache diagnosis is made...
  29. ncbi request reprint Do community based self-reading sphygmomanometers improve detection of hypertension? A feasibility study
    William Hamilton
    Division of Primary Care, University of Bristol, Cotham House, Bristol B56 6JL
    J Public Health Med 25:125-30. 2003
    ..Those who rarely use medical services are less likely to have their blood pressure (BP) measured. We hypothesized that open access self-reading BP measurement would detect previously unrecognized hypertension...
  30. pmc Incidence of fatigue symptoms and diagnoses presenting in UK primary care from 1990 to 2001
    Arlene M Gallagher
    Centre for Psychiatry and Department of Information Services, Queen Mary School of Medicine and Dentistry, St Bartholomew s Hospital, London EC1A 7BE
    J R Soc Med 97:571-5. 2004
    ..This is likely to reflect fashions in diagnostic labelling rather than true changes in incidence...
  31. pmc The quality of record keeping in primary care: a comparison of computerised, paper and hybrid systems
    William T Hamilton
    Division of Primary Health Care, University of Bristol
    Br J Gen Pract 53:929-33; discussion 933. 2003
    ..Computerised record keeping in primary care is increasing. However, no study has systematically examined the completeness of computer records in practices using different forms of record keeping...
  32. ncbi request reprint Risk factors for ill health insurance claims
    William T Hamilton
    Division of Primary Care, University of Bristol, Cotham House, Bristol BS6 6JL, UK
    J Insur Med 35:17-25. 2003
    ..The strength and significance of such factors were assessed and a predictive model was developed...
  33. pmc GPs can separate oncological wheat from chaff
    William T Hamilton
    BMJ 326:397. 2003