Neil Hall

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi request reprint The genome of the African trypanosome Trypanosoma brucei
    Matthew Berriman
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Science 309:416-22. 2005
  2. ncbi request reprint Advanced sequencing technologies and their wider impact in microbiology
    Neil Hall
    School of Biological Sciences, Biosciences Building, Crown Street, University of Liverpool, Liverpool L69 7ZB, UK
    J Exp Biol 210:1518-25. 2007
  3. pmc Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections
    Rosalind M K Stewart
    Institute of Infection and Global Health, University of Liverpool, Duncan Building, Daulby Street, Liverpool, L69 3GA, United Kingdom
    J Clin Microbiol 49:993-1003. 2011
  4. pmc Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages
    Azra Yasmin
    School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
    J Bacteriol 192:1122-30. 2010
  5. ncbi request reprint A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics
    Claire Whitton
    Ashworth Laboratories, Institution of Cell, Animal and Polulation Biology, School of Biological Sciences, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Mol Biochem Parasitol 137:215-27. 2004
  6. ncbi request reprint Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes
    Malcolm J Gardner
    Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:134-7. 2005
  7. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
  8. ncbi request reprint Comparative genomics of malaria parasites
    Neil Hall
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20851, USA
    Curr Opin Genet Dev 15:609-13. 2005
  9. ncbi request reprint Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    William C Nierman
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    Nature 438:1151-6. 2005
  10. doi request reprint Meeting report: the fourth Genomic Standards Consortium (GSC) workshop
    Dawn Field
    NERC Centre for Ecology and Hydrology, Mansfield Road, Oxford, OX1 3SR United Kingdom
    OMICS 12:101-8. 2008

Collaborators

Detail Information

Publications22

  1. ncbi request reprint The genome of the African trypanosome Trypanosoma brucei
    Matthew Berriman
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Science 309:416-22. 2005
    ..brucei and the greatest in L. major. Horizontal transfer of genes of bacterial origin has contributed to some of the metabolic differences in these parasites, and a number of novel potential drug targets have been identified...
  2. ncbi request reprint Advanced sequencing technologies and their wider impact in microbiology
    Neil Hall
    School of Biological Sciences, Biosciences Building, Crown Street, University of Liverpool, Liverpool L69 7ZB, UK
    J Exp Biol 210:1518-25. 2007
    ..While this review will concentrate on microorganisms, many of the important arguments about the need to measure and understand variation at the species, population and ecosystem level will hold true for many other biological systems...
  3. pmc Genetic characterization indicates that a specific subpopulation of Pseudomonas aeruginosa is associated with keratitis infections
    Rosalind M K Stewart
    Institute of Infection and Global Health, University of Liverpool, Duncan Building, Daulby Street, Liverpool, L69 3GA, United Kingdom
    J Clin Microbiol 49:993-1003. 2011
    ..Thus, the keratitis isolates were associated with specific characteristics, indicating that a subpopulation of P. aeruginosa is adapted to cause corneal infection...
  4. pmc Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages
    Azra Yasmin
    School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
    J Bacteriol 192:1122-30. 2010
    ..The eight phages were tested for their ability to package host DNA, and three were shown to be very effective for generalized transduction of naive host cells of the laboratory strains OG1RF and JH2-2...
  5. ncbi request reprint A genome sequence survey of the filarial nematode Brugia malayi: repeats, gene discovery, and comparative genomics
    Claire Whitton
    Ashworth Laboratories, Institution of Cell, Animal and Polulation Biology, School of Biological Sciences, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Mol Biochem Parasitol 137:215-27. 2004
    ..B. malayi is estimated to have over 18,500 protein-coding genes...
  6. ncbi request reprint Genome sequence of Theileria parva, a bovine pathogen that transforms lymphocytes
    Malcolm J Gardner
    Institute for Genomic Research TIGR, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:134-7. 2005
    ..Several biosynthetic pathways are incomplete or absent, suggesting substantial metabolic dependence on the host cell. One protein family that may generate parasite antigenic diversity is not telomere-associated...
  7. ncbi request reprint Comparative genomics of trypanosomatid parasitic protozoa
    Najib M El-Sayed
    Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 309:404-9. 2005
    ..Contrary to recent reports, our analyses reveal no evidence that these species are descended from an ancestor that contained a photosynthetic endosymbiont...
  8. ncbi request reprint Comparative genomics of malaria parasites
    Neil Hall
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20851, USA
    Curr Opin Genet Dev 15:609-13. 2005
    ..Recent research has led to the description of a motif that is conserved across Plasmodium species and which plays a central role in protein export into the host cell...
  9. ncbi request reprint Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    William C Nierman
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    Nature 438:1151-6. 2005
    ..The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus...
  10. doi request reprint Meeting report: the fourth Genomic Standards Consortium (GSC) workshop
    Dawn Field
    NERC Centre for Ecology and Hydrology, Mansfield Road, Oxford, OX1 3SR United Kingdom
    OMICS 12:101-8. 2008
    ..g., compliant with MIGS/MIMS), but also be extended to include a variety of data processing and calculations. Further information about the Genomic Standards Consortium and its range of activities can be found at http://gensc.org...
  11. ncbi request reprint Genome of the host-cell transforming parasite Theileria annulata compared with T. parva
    Arnab Pain
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Science 309:131-3. 2005
    ....
  12. pmc Gene arrays at Pneumocystis carinii telomeres
    Scott P Keely
    Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, Cincinnati, Ohio 45267, USA
    Genetics 170:1589-600. 2005
    ..Long mononucleotide tracts were present in some MSR genes. These unstable sequences can be expected to suffer frequent frameshift mutations, providing P. carinii with another mechanism to generate antigen variation...
  13. pmc An ancestral oomycete locus contains late blight avirulence gene Avr3a, encoding a protein that is recognized in the host cytoplasm
    Miles R Armstrong
    Plant Pathogen Interactions Programme, Scottish Crop Research Institute, Invergowrie, DD2 5DA Dundee, UK
    Proc Natl Acad Sci U S A 102:7766-71. 2005
    ..We suggest that Avr3a has undergone gene duplication and that an allele evading recognition by R3a arose under positive selection...
  14. ncbi request reprint Genome sequence of the human malaria parasite Plasmodium falciparum
    Malcolm J Gardner
    The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, Maryland 20850, USA
    Nature 419:498-511. 2002
    ..The genome sequence provides the foundation for future studies of this organism, and is being exploited in the search for new drugs and vaccines to fight malaria...
  15. pmc The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism
    Neil Hall
    The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK
    Nucleic Acids Res 31:4864-73. 2003
    ..Genetic polymorphisms are exceptionally rare in sequences located within and around the strand-switches between several gene clusters...
  16. pmc GeneDB: a resource for prokaryotic and eukaryotic organisms
    Christiane Hertz-Fowler
    The Wellcome Trust Sanger Institute, The Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Nucleic Acids Res 32:D339-43. 2004
    ..The current release stores 11 datasets of which six are curated and maintained by biologists, who review and incorporate information from the scientific literature, public databases and the respective research communities...
  17. ncbi request reprint Insight into the genome of Aspergillus fumigatus: analysis of a 922 kb region encompassing the nitrate assimilation gene cluster
    Arnab Pain
    The Pathogen Sequencing Unit, The Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge CB10 1SA, UK
    Fungal Genet Biol 41:443-53. 2004
    ..We observed large scale synteny between A. fumigatus and Aspergillus nidulans by comparing this sequence to the A. nidulans genetic map of linkage group VIII...
  18. ncbi request reprint Gene synteny and evolution of genome architecture in trypanosomatids
    Elodie Ghedin
    Parasity Genomics, The Institute for Genomics Research, 9712 Medical Center Dr Rockville, MD 20850, USA
    Mol Biochem Parasitol 134:183-91. 2004
    ..major by examining the regions near breakage points of the synteny. This is the first such element found in L. major suggesting that retroelements were found in the common ancestor of all three species...
  19. ncbi request reprint A transcriptomic analysis of the phylum Nematoda
    John Parkinson
    Hospital for Sick Children, 555 University Avenue, Departments of Biochemistry and Medical Genetics and Microbiology, University of Toronto, Toronto, Ontario M5G 1X8, Canada
    Nat Genet 36:1259-67. 2004
    ..Nematode-specific families are particularly interesting as drug and vaccine targets...
  20. ncbi request reprint The genome of model malaria parasites, and comparative genomics
    Jane Carlton
    The Institute for Genomic Research, Rockville, MD 20850, USA
    Curr Issues Mol Biol 7:23-37. 2005
    ..This is a stimulating time for comparative genomics of model and human malaria parasites, which promises to produce useful results for the development of antimalarial drugs and vaccines...
  21. ncbi request reprint A case for a Glossina genome project
    Serap Aksoy
    Yale University School of Medicine, 60 College Street, 606 LEPH, New Haven, CT 06520, USA
    Trends Parasitol 21:107-11. 2005
    ..An international consortium is now in place to further efforts to lead to a full genome project...
  22. ncbi request reprint The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei
    Matthew Berriman
    The Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK
    Mol Biochem Parasitol 122:131-40. 2002
    ..Unexpected conservation of sequences, including pseudogenes, indicates that the multiple ESs could have arisen through a relatively recent amplification of a single ES...