Ailsa J Hall

Summary

Affiliation: University of St Andrews
Country: UK

Publications

  1. pmc Phocid seal leptin: tertiary structure and hydrophobic receptor binding site preservation during distinct leptin gene evolution
    John A Hammond
    Institute for Animal Health, Compton, Newbury, UK
    PLoS ONE 7:e35395. 2012
  2. ncbi request reprint Exposure to persistent organic pollutants and first-year survival probability in gray seal pups
    Ailsa J Hall
    Sea Mammal Research Unit, Scottish Oceans Institute, University of St Andrews, St Andrews, Fife, KY16 8LB, Scotland
    Environ Sci Technol 43:6364-9. 2009
  3. ncbi request reprint Changes in blubber contaminant concentrations in California sea lions (Zalophus californianus) associated with weight loss and gain during rehabilitation
    A J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife, KY16 8LB, UK
    Environ Sci Technol 42:4181-7. 2008
  4. ncbi request reprint Annual, seasonal and individual variation in hematology and clinical blood chemistry profiles in bottlenose dolphins (Tursiops truncatus) from Sarasota Bay, Florida
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, Fife, Scotland, KY16 8LB, United Kingdom
    Comp Biochem Physiol A Mol Integr Physiol 148:266-77. 2007
  5. ncbi request reprint Polychlorinated biphenyls, DDT, polybrominated diphenyl ethers, and organic pesticides in United Kingdom harbor seals (Phoca vitulina)--mixed exposures and thyroid homeostasis
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife KY18 8LB, United Kingdom
    Environ Toxicol Chem 26:851-61. 2007
  6. pmc Individual-based model framework to assess population consequences of polychlorinated biphenyl exposure in bottlenose dolphins
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Scotland, United Kingdom
    Environ Health Perspect 114:60-4. 2006
  7. ncbi request reprint Molecular cloning and expression of leptin in gray and harbor seal blubber, bone marrow, and lung and its potential role in marine mammal respiratory physiology
    John A Hammond
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Scotland, KY16 8LB, UK
    Am J Physiol Regul Integr Comp Physiol 289:R545-R553. 2005
  8. pmc The risk of infection from polychlorinated biphenyl exposure in the harbor porpoise (Phocoena phocoena): a case-control approach
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife, United Kingdom
    Environ Health Perspect 114:704-11. 2006
  9. ncbi request reprint Polybrominated diphenyl ethers (PBDEs) in grey seals during their first year of life--are they thyroid hormone endocrine disrupters?
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, Fife, UK
    Environ Pollut 126:29-37. 2003
  10. ncbi request reprint Isolation of two cytochrome P450 cDNAs, CYP1A1 and CYP1A2, from harp seal (Phoca groenlandica) and grey seal (Halichoerus grypus)
    Rachel E Tilley
    Centre for Biomolecular Sciences, University of St Andrews, St Andrews, UK
    Comp Biochem Physiol C Toxicol Pharmacol 132:181-91. 2002

Detail Information

Publications18

  1. pmc Phocid seal leptin: tertiary structure and hydrophobic receptor binding site preservation during distinct leptin gene evolution
    John A Hammond
    Institute for Animal Health, Compton, Newbury, UK
    PLoS ONE 7:e35395. 2012
    ..We suggest that this additional surfactant requirement is met by the leptin pulmonary surfactant production pathway which normally appears only to function in the mammalian foetus...
  2. ncbi request reprint Exposure to persistent organic pollutants and first-year survival probability in gray seal pups
    Ailsa J Hall
    Sea Mammal Research Unit, Scottish Oceans Institute, University of St Andrews, St Andrews, Fife, KY16 8LB, Scotland
    Environ Sci Technol 43:6364-9. 2009
    ..These compounds were not the most abundant in the blubber, suggesting further studies into their toxicological effects in this species are necessary. The specific mechanisms driving the reduction in survivorship remain unknown...
  3. ncbi request reprint Changes in blubber contaminant concentrations in California sea lions (Zalophus californianus) associated with weight loss and gain during rehabilitation
    A J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife, KY16 8LB, UK
    Environ Sci Technol 42:4181-7. 2008
    ..These results indicate the importance of considering the energetic contextwhen sampling blubberfor long-term contaminant monitoring and suggest an initial approach to adjust for such differences...
  4. ncbi request reprint Annual, seasonal and individual variation in hematology and clinical blood chemistry profiles in bottlenose dolphins (Tursiops truncatus) from Sarasota Bay, Florida
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, Fife, Scotland, KY16 8LB, United Kingdom
    Comp Biochem Physiol A Mol Integr Physiol 148:266-77. 2007
    ..Again, nutritional and thermal constraints seem to be the most likely environmental factors influencing these patterns...
  5. ncbi request reprint Polychlorinated biphenyls, DDT, polybrominated diphenyl ethers, and organic pesticides in United Kingdom harbor seals (Phoca vitulina)--mixed exposures and thyroid homeostasis
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife KY18 8LB, United Kingdom
    Environ Toxicol Chem 26:851-61. 2007
    ....
  6. pmc Individual-based model framework to assess population consequences of polychlorinated biphenyl exposure in bottlenose dolphins
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Scotland, United Kingdom
    Environ Health Perspect 114:60-4. 2006
    ..Such data require continued efforts directed toward long-term studies of known individuals in wild and semiwild populations...
  7. ncbi request reprint Molecular cloning and expression of leptin in gray and harbor seal blubber, bone marrow, and lung and its potential role in marine mammal respiratory physiology
    John A Hammond
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Scotland, KY16 8LB, UK
    Am J Physiol Regul Integr Comp Physiol 289:R545-R553. 2005
    ..Finally, we report the substantial inadequacies of using heterologous antibodies to measure leptin in unextracted gray seal serum...
  8. pmc The risk of infection from polychlorinated biphenyl exposure in the harbor porpoise (Phocoena phocoena): a case-control approach
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife, United Kingdom
    Environ Health Perspect 114:704-11. 2006
    ..However, as with case-control studies in human and veterinary epidemiology, unforeseen misclassification errors may result in biased risk estimates in either direction...
  9. ncbi request reprint Polybrominated diphenyl ethers (PBDEs) in grey seals during their first year of life--are they thyroid hormone endocrine disrupters?
    Ailsa J Hall
    Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, Fife, UK
    Environ Pollut 126:29-37. 2003
    ..Such an association is not alone sufficient evidence for a cause and effect relationship, however it is in accordance with the hypothesis that these compounds are endocrine disrupters in grey seal pups...
  10. ncbi request reprint Isolation of two cytochrome P450 cDNAs, CYP1A1 and CYP1A2, from harp seal (Phoca groenlandica) and grey seal (Halichoerus grypus)
    Rachel E Tilley
    Centre for Biomolecular Sciences, University of St Andrews, St Andrews, UK
    Comp Biochem Physiol C Toxicol Pharmacol 132:181-91. 2002
    ..The CYP1A sequence information presented in this study has provided the necessary data for the future production of species-specific probes for the use as biomarkers of environmental contaminant exposure...
  11. ncbi request reprint Cryostorage of hepatic microsomes from two marine mammal species: effects on cytochrome P450-monooxygenase activities and content
    Rachel E Tilley
    Centre for Biomolecular Sciences, University of St Andrews, St Andrews KY16 9SB, UK
    Mar Pollut Bull 46:654-8. 2003
  12. ncbi request reprint The immunocompetence handicap hypothesis in two sexually dimorphic pinniped species--is there a sex difference in immunity during early development?
    Ailsa J Hall
    NERC Sea Mammal Research Unit, Gatty Marine Laboratory, University of St Andrews, St Andrews, Fife KY16 8LB, UK
    Dev Comp Immunol 27:629-37. 2003
    ..Southern elephant seals had higher concentrations than grey seals and total leucocyte counts in the former were among the highest reported for mammals...
  13. ncbi request reprint Identification and real-time PCR quantification of Phocine distemper virus from two colonies of Scottish grey seals in 2002
    John A Hammond
    NERC Sea Mammal Research Unit, University of St Andrews, Gatty Marine Laboratory, St Andrews, Fife KY16 8LB, UK
    J Gen Virol 86:2563-7. 2005
    ..In some seals the virus is able to replicate from the primary site of infection. This study provides evidence that grey seals may have an active role in the spread of PDV during an epidemic...
  14. ncbi request reprint The role of organochlorines in cancer-associated mortality in California sea lions (Zalophus californianus)
    Gina M Ylitalo
    Environmental Conservation Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, 2725 Montlake Boulevard East, Seattle, WA 98112, USA
    Mar Pollut Bull 50:30-9. 2005
    ..Age, sex, mass and length did not affect the probability of dying from carcinoma...
  15. ncbi request reprint Absorption of decabromodiphenyl ether and other organohalogen chemicals by grey seals (Halichoerus grypus)
    Gareth O Thomas
    Department of Environmental Science, Institute of Environmental and Natural Sciences, Lancaster University, Lancaster LA1 4YQ, UK
    Environ Pollut 133:581-6. 2005
    ..Current understanding of the mechanism of absorption of organohalogen chemicals and the potential for accumulation of decabromodiphenyl ether will need reassessing in the light of these results...
  16. ncbi request reprint Comparison of polychlorinated biphenyl (PCB) induced effects on innate immune functions in harbour and grey seals
    John A Hammond
    School of Life Sciences, Heriot Watt University, Edinburgh EH14 4AS, UK
    Aquat Toxicol 74:126-38. 2005
    ....
  17. ncbi request reprint Transplacental transfer of organochlorines in California sea lions (Zalophus californianus)
    Denise J Greig
    The Marine Mammal Center, 1065 Fort Cronkhite, Sausalito, California 94965, USA
    Environ Toxicol Chem 26:37-44. 2007
    ..Fetal TEQ was explained by maternal TEQ and maternal age. The ability to predict contaminant concentrations in fetal blubber from maternal parameters is important for developing risk assessment models for marine mammals...
  18. ncbi request reprint Blood chemistry in southern elephant seal mothers and pups during lactation reveals no effect of handling
    Georg H Engelhard
    Alterra Institute, Marine and Coastal Zone Research, P O Box 167, 1790 AD Den Burg, The Netherlands
    Comp Biochem Physiol A Mol Integr Physiol 133:367-78. 2002
    ..g. food limitation, suspected to be involved in population declines...