Jcg Halford

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi request reprint Pharmacotherapy for obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 46:6-10. 2006
  2. ncbi request reprint Serotonergic drugs : effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs 67:27-55. 2007
  3. ncbi request reprint Clinical pharmacotherapy for obesity: current drugs and those in advanced development
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:637-46. 2004
  4. ncbi request reprint Effect of television advertisements for foods on food consumption in children
    Jason C G Halford
    Department of Psychology, Kissileff Laboratory for the Study of Human Ingestive Behaviour, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 42:221-5. 2004
  5. ncbi request reprint The pharmacology of human appetite expression
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, Department of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:221-40. 2004
  6. doi request reprint The effects of sibutramine on the microstructure of eating behaviour and energy expenditure in obese women
    J C G Halford
    Kissileff Laboratory, School of Psychology, University of Liverpool, Liverpool, UK
    J Psychopharmacol 24:99-109. 2010
  7. ncbi request reprint Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    School of Psychology, University of Liverpool, Liverpool L69 7ZA, UK
    Curr Drug Targets 6:201-13. 2005
  8. ncbi request reprint A preliminary investigation into the relationship between anabolic-androgenic steroid use and the symptoms of reverse anorexia in both current and ex-users
    Jon C Cole
    Psychology Department, Liverpool University, Liverpool, L69 7ZA, UK
    Psychopharmacology (Berl) 166:424-9. 2003
  9. doi request reprint A guide to analysing Universal Eating Monitor data: assessing the impact of different analysis techniques
    Terence M Dovey
    Centre for Research into Eating Disorders, Department of Human Sciences, Loughborough University, Loughborough, Leicestershire, UK
    Physiol Behav 96:78-84. 2009
  10. ncbi request reprint The hypothalamus and obesity
    Joanne A Harrold
    School of Psychology, University of Liverpool, Liverpool, L69 7ZA, UK
    Recent Pat CNS Drug Discov 1:305-14. 2006

Detail Information

Publications22

  1. ncbi request reprint Pharmacotherapy for obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 46:6-10. 2006
    ..Despite this, in the XENDOS trial, the modest placebo-subtract weight loss produced by orlistat (2.8 kg) reduced the incidence of diabetes by over a third. Recent data on the potential anti-obesity drug rimonabant are also reviewed...
  2. ncbi request reprint Serotonergic drugs : effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs 67:27-55. 2007
    ..The hope is that these drugs will not only be free of their predecessors' adverse effect profiles, but will also be equally or more effective at regulating appetite and controlling bodyweight...
  3. ncbi request reprint Clinical pharmacotherapy for obesity: current drugs and those in advanced development
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:637-46. 2004
    ..Wider use of pharmacotherapy and enhanced efficacy for the next generation of anti-obesity drugs certainly promise to reduce obesity related illness if not halt the rise in obesity per se...
  4. ncbi request reprint Effect of television advertisements for foods on food consumption in children
    Jason C G Halford
    Department of Psychology, Kissileff Laboratory for the Study of Human Ingestive Behaviour, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 42:221-5. 2004
    ..As suggested the relationship between TV viewing and childhood obesity appears not merely a matter of excessive sedentary activity. Exposure to food adverts promotes consumption...
  5. ncbi request reprint The pharmacology of human appetite expression
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, Department of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:221-40. 2004
    ..However, such an understanding must be based on knowledge of the effect of the treatment on meal size, eating rate, meal pattern, food choice and the subjective experience of appetite flux (hunger and satiety), and notjust food intake...
  6. doi request reprint The effects of sibutramine on the microstructure of eating behaviour and energy expenditure in obese women
    J C G Halford
    Kissileff Laboratory, School of Psychology, University of Liverpool, Liverpool, UK
    J Psychopharmacol 24:99-109. 2010
    ..Changes in within-meal appetite ratings appear particularly sensitive to drug-induced enhancement of satiation, and may provide key indices for assessing the therapeutic potential of novel anti-obesity drugs...
  7. ncbi request reprint Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    School of Psychology, University of Liverpool, Liverpool L69 7ZA, UK
    Curr Drug Targets 6:201-13. 2005
    ..Hopefully, such drugs will be as or even more effective at regulating appetite and controlling body weight, and will also be free of their predecessors' side effect...
  8. ncbi request reprint A preliminary investigation into the relationship between anabolic-androgenic steroid use and the symptoms of reverse anorexia in both current and ex-users
    Jon C Cole
    Psychology Department, Liverpool University, Liverpool, L69 7ZA, UK
    Psychopharmacology (Berl) 166:424-9. 2003
    ..To establish whether the symptoms of reverse anorexia continue with the cessation of anabolic-androgenic steroid (AAS) use in male body builders...
  9. doi request reprint A guide to analysing Universal Eating Monitor data: assessing the impact of different analysis techniques
    Terence M Dovey
    Centre for Research into Eating Disorders, Department of Human Sciences, Loughborough University, Loughborough, Leicestershire, UK
    Physiol Behav 96:78-84. 2009
    ..017). Whilst the relative merits of various approaches to microstructural analysis of eating behaviour remain to be fully evaluated, the case for some form of standardised analytic approach may need to be addressed...
  10. ncbi request reprint The hypothalamus and obesity
    Joanne A Harrold
    School of Psychology, University of Liverpool, Liverpool, L69 7ZA, UK
    Recent Pat CNS Drug Discov 1:305-14. 2006
    ..The true relevance of many of these to the regulation of human energy balance remains uncertain, but some novel anti-obesity drugs aimed at these targets are likely to emerge in the next few years...
  11. doi request reprint Neuropharmacology of human appetite expression
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, United Kingdom
    Dev Disabil Res Rev 14:158-64. 2008
    ..All these drugs act by modifying the expression of human appetite. An assessment of a drug's effects on caloric intake and feelings of hunger and satiety is necessary before they can be considered for clinical use...
  12. doi request reprint Pharmacological management of appetite expression in obesity
    Jason C G Halford
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Nat Rev Endocrinol 6:255-69. 2010
    ..Rational interventions designed specifically to modulate these processes could limit the normally aversive consequences of caloric restriction and maximize an individual's capacity to successfully gain control over their appetite...
  13. ncbi request reprint Obesity drugs in clinical development
    Jason C G Halford
    University of Liverpool, Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, Liverpool, UK
    Curr Opin Investig Drugs 7:312-8. 2006
    ..Of these, only rimonabant has got as far as completing phase III clinical trials. This review will provide an overview of the most prominent drugs currently undergoing clinical development as potential anti-obesity therapies...
  14. ncbi request reprint Beyond-brand effect of television (TV) food advertisements/commercials on caloric intake and food choice of 5-7-year-old children
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, University of Liverpool, Liverpool L69 7ZA, UK
    Appetite 49:263-7. 2007
    ..Beyond their effects on brand choice, exposure to food advertisements (commercials) promotes over-consumption in younger children...
  15. ncbi request reprint Orphan G-protein-coupled receptors : strategies for identifying ligands and potential for use in eating disorders
    Joanne A Harrold
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs R D 8:287-99. 2007
    ..Consequently, hypophagic treatments may be of potential benefit in normal, overweight or obese individuals displaying aberrant (out of control) eating behaviour...
  16. ncbi request reprint Food neophobia and 'picky/fussy' eating in children: a review
    Terence M Dovey
    Department of Psychology, Staffordshire University, College Road, Stoke on Trent, Staffordshire ST4 2DE, UK
    Appetite 50:181-93. 2008
    ..Behavioural interventions, focusing on early life exposure, could be developed to attenuate food neophobia and 'picky/fussy' eating in children, so promoting the ready acceptance and independent choice of fruits and vegetables...
  17. ncbi request reprint Adolescence and the diet-dieting disparity: healthy food choice or risky health behaviour?
    Paul J Lattimore
    Department of Psychology, Chester College of Higher Education, UK
    Br J Health Psychol 8:451-63. 2003
    ..It was predicted that dieters would make healthier food choices compared to non-dieters and that measures of eating psychopathology would be associated with food choice...
  18. ncbi request reprint Effects of insulin-induced hypoglycaemia on energy intake and food choice at a subsequent test meal
    Shivani Dewan
    Diabetes and Endocrinology Research Group, University Hospital Aintree, Liverpool, UK
    Diabetes Metab Res Rev 20:405-10. 2004
    ..Hypoglycaemia is assumed to increase food intake, but there is little data on the magnitude or qualitative nature of this effect. We have therefore investigated the effects of insulin-induced hypoglycaemia on food intake at a test meal...
  19. doi request reprint Autoradiographic analysis of ghrelin receptors in the rat hypothalamus
    Joanne A Harrold
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, U K
    Brain Res 1196:59-64. 2008
    ..We suggest that this may relate to the paradigm employed to modify nutritional status in the study or could indicate that peripheral ghrelin is unlikely to be the major source of ghrelin that acts in many hypothalamic sites...
  20. ncbi request reprint Characterization of olanzapine-induced weight gain in rats
    Andrew J Goudie
    Psychology Department, Eleanor Rathbone Building, Liverpool University, Liverpool, UK
    J Psychopharmacol 16:291-6. 2002
    ..However, it remains to be determined how closely rodent models mimic the clinical situation and whether the mechanism(s) involved in the weight gain we have observed are the same as those involved in the clinical use of these drugs...
  21. ncbi request reprint Editorial
    Jason C G Halford
    Curr Drug Targets 6:143-4. 2005
  22. ncbi request reprint Is there a role for ghrelin and peptide-YY in the pathogenesis of obesity in adults with acquired structural hypothalamic damage?
    Christina Daousi
    University Hospital Aintree, Diabetes and Endocrinology Research Group, Clinical Sciences Center, Longmoor Lane, Liverpool L9 7AL, United Kingdom
    J Clin Endocrinol Metab 90:5025-30. 2005
    ..Obesity is a common sequel to hypothalamic tumors and their treatment, but the underlying mechanisms are not fully established...