Jason C G Halford

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi Clinical pharmacotherapy for obesity: current drugs and those in advanced development
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:637-46. 2004
  2. ncbi Beyond-brand effect of television food advertisements on food choice in children: the effects of weight status
    Jason Cg Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, University of Liverpool, Liverpool L69 7ZA, UK
    Public Health Nutr 11:897-904. 2008
  3. doi Serotonergic anti-obesity agents: past experience and future prospects
    Jason C G Halford
    Experimental Psychology, University of Liverpool, Liverpool, UK
    Drugs 71:2247-55. 2011
  4. doi Satiety-enhancing products for appetite control: science and regulation of functional foods for weight management
    Jason C G Halford
    Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool L69 7ZA, UK
    Proc Nutr Soc 71:350-62. 2012
  5. pmc The effect of Korean pine nut oil (PinnoThin) on food intake, feeding behaviour and appetite: a double-blind placebo-controlled trial
    Georgina M Hughes
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK
    Lipids Health Dis 7:6. 2008
  6. ncbi Separate systems for serotonin and leptin in appetite control
    J C Halford
    Department of Psychology, University of Liverpool, UK
    Ann Med 32:222-32. 2000
  7. ncbi Serotonergic drugs : effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs 67:27-55. 2007
  8. ncbi Beyond-brand effect of television (TV) food advertisements/commercials on caloric intake and food choice of 5-7-year-old children
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, University of Liverpool, Liverpool L69 7ZA, UK
    Appetite 49:263-7. 2007
  9. doi Children's food preferences: effects of weight status, food type, branding and television food advertisements (commercials)
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, UK
    Int J Pediatr Obes 3:31-8. 2008
  10. doi From Claude Bernard to Walter Cannon. Emergence of the concept of homeostasis
    Steven J Cooper
    School of Psychology, University of Liverpool, Bedford Street South, Liverpool, UK
    Appetite 51:419-27. 2008

Detail Information

Publications37

  1. ncbi Clinical pharmacotherapy for obesity: current drugs and those in advanced development
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:637-46. 2004
    ..Wider use of pharmacotherapy and enhanced efficacy for the next generation of anti-obesity drugs certainly promise to reduce obesity related illness if not halt the rise in obesity per se...
  2. ncbi Beyond-brand effect of television food advertisements on food choice in children: the effects of weight status
    Jason Cg Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, University of Liverpool, Liverpool L69 7ZA, UK
    Public Health Nutr 11:897-904. 2008
    ..To investigate the effect of television food advertising on children's food intake, specifically whether childhood obesity is related to a greater susceptibility to food promotion...
  3. doi Serotonergic anti-obesity agents: past experience and future prospects
    Jason C G Halford
    Experimental Psychology, University of Liverpool, Liverpool, UK
    Drugs 71:2247-55. 2011
    ..The serotonergic system remains a viable target for anti-obesity treatment. In this review, we examine the limited behavioural data available on these two new CNS-acting appetite suppressants...
  4. doi Satiety-enhancing products for appetite control: science and regulation of functional foods for weight management
    Jason C G Halford
    Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Liverpool L69 7ZA, UK
    Proc Nutr Soc 71:350-62. 2012
    ..Nonetheless, we possess the methodological tools, which when employed in appropriate designs, are sufficient to support health claims...
  5. pmc The effect of Korean pine nut oil (PinnoThin) on food intake, feeding behaviour and appetite: a double-blind placebo-controlled trial
    Georgina M Hughes
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK
    Lipids Health Dis 7:6. 2008
    ..Collectively, these data suggest that PinnoThin may exert satiating effects consistent with its known action on CCK and GLP-1 release, and previously observed effects on self-reported appetite ratings...
  6. ncbi Separate systems for serotonin and leptin in appetite control
    J C Halford
    Department of Psychology, University of Liverpool, UK
    Ann Med 32:222-32. 2000
    ..At a conceptual level, these may represent the distinction between 'satiety' and 'drive'. Interestingly, both 5-HT and leptin modulate the action of NPY, which may form a part of a common output pathway for the expression of appetite...
  7. ncbi Serotonergic drugs : effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs 67:27-55. 2007
    ..The hope is that these drugs will not only be free of their predecessors' adverse effect profiles, but will also be equally or more effective at regulating appetite and controlling bodyweight...
  8. ncbi Beyond-brand effect of television (TV) food advertisements/commercials on caloric intake and food choice of 5-7-year-old children
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, University of Liverpool, Liverpool L69 7ZA, UK
    Appetite 49:263-7. 2007
    ..Beyond their effects on brand choice, exposure to food advertisements (commercials) promotes over-consumption in younger children...
  9. doi Children's food preferences: effects of weight status, food type, branding and television food advertisements (commercials)
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, UK
    Int J Pediatr Obes 3:31-8. 2008
    ..This suggests that television food advertisement exposure can produce the same 'obesigenic' food preference response found in overweight and obese children in their normal weight counterparts...
  10. doi From Claude Bernard to Walter Cannon. Emergence of the concept of homeostasis
    Steven J Cooper
    School of Psychology, University of Liverpool, Bedford Street South, Liverpool, UK
    Appetite 51:419-27. 2008
    ....
  11. doi Neuropharmacology of human appetite expression
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, United Kingdom
    Dev Disabil Res Rev 14:158-64. 2008
    ..All these drugs act by modifying the expression of human appetite. An assessment of a drug's effects on caloric intake and feelings of hunger and satiety is necessary before they can be considered for clinical use...
  12. doi Pharmacological management of appetite expression in obesity
    Jason C G Halford
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Nat Rev Endocrinol 6:255-69. 2010
    ..Rational interventions designed specifically to modulate these processes could limit the normally aversive consequences of caloric restriction and maximize an individual's capacity to successfully gain control over their appetite...
  13. ncbi 5-HT(2C) Receptor Agonists and the Control of Appetite
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, L69 7ZA, UK
    Handb Exp Pharmacol 209:349-56. 2012
    ..The effects of lorcaserin on eating behaviour remain to be characterised as does its behavioural specificity...
  14. ncbi Obesity drugs in clinical development
    Jason C G Halford
    University of Liverpool, Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, Eleanor Rathbone Building, Bedford Street South, Liverpool, UK
    Curr Opin Investig Drugs 7:312-8. 2006
    ..Of these, only rimonabant has got as far as completing phase III clinical trials. This review will provide an overview of the most prominent drugs currently undergoing clinical development as potential anti-obesity therapies...
  15. ncbi Pharmacotherapy for obesity
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 46:6-10. 2006
    ..Despite this, in the XENDOS trial, the modest placebo-subtract weight loss produced by orlistat (2.8 kg) reduced the incidence of diabetes by over a third. Recent data on the potential anti-obesity drug rimonabant are also reviewed...
  16. ncbi Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity
    Jason C G Halford
    School of Psychology, University of Liverpool, Liverpool L69 7ZA, UK
    Curr Drug Targets 6:201-13. 2005
    ..Hopefully, such drugs will be as or even more effective at regulating appetite and controlling body weight, and will also be free of their predecessors' side effect...
  17. ncbi Pharmacology of appetite suppression: implication for the treatment of obesity
    J C Halford
    Department of Psychology, University of Liverpool, UK
    Curr Drug Targets 2:353-70. 2001
    ..Such compounds used in combination with life style changes and dietary intervention may be critical in dealing with the rising world epidemic of obesity...
  18. doi Food commercials increase preference for energy-dense foods, particularly in children who watch more television
    Emma J Boyland
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, United Kingdom
    Pediatrics 128:e93-100. 2011
    ..Our aim was to determine if levels of television viewing (a proxy measure for habitual commercial exposure) affect children's food preference responses to television food commercials...
  19. ncbi The hypothalamus and obesity
    Joanne A Harrold
    School of Psychology, University of Liverpool, Liverpool, L69 7ZA, UK
    Recent Pat CNS Drug Discov 1:305-14. 2006
    ..The true relevance of many of these to the regulation of human energy balance remains uncertain, but some novel anti-obesity drugs aimed at these targets are likely to emerge in the next few years...
  20. doi Television advertising and branding. Effects on eating behaviour and food preferences in children
    Emma J Boyland
    Department of Experimental Psychology, Institute of Psychology, Health and Society, University of Liverpool, Liverpool L69 7ZA, United Kingdom
    Appetite 62:236-41. 2013
    ....
  21. ncbi The pharmacology of human appetite expression
    Jason C G Halford
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, Department of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool, L69 7ZA, UK
    Curr Drug Targets 5:221-40. 2004
    ..However, such an understanding must be based on knowledge of the effect of the treatment on meal size, eating rate, meal pattern, food choice and the subjective experience of appetite flux (hunger and satiety), and notjust food intake...
  22. ncbi Effect of television advertisements for foods on food consumption in children
    Jason C G Halford
    Department of Psychology, Kissileff Laboratory for the Study of Human Ingestive Behaviour, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 42:221-5. 2004
    ..As suggested the relationship between TV viewing and childhood obesity appears not merely a matter of excessive sedentary activity. Exposure to food adverts promotes consumption...
  23. doi Food choice and overconsumption: effect of a premium sports celebrity endorser
    Emma J Boyland
    Kissileff Laboratory for Study of Human Ingestive Behavior, Department of Experimental Psychology, University of Liverpool, Liverpool, United Kingdom
    J Pediatr 163:339-43. 2013
    ..To determine whether exposure to celebrity endorsement in television (TV) food advertising and a nonfood context would affect ad libitum intake of the endorsed product and a perceived alternative brand...
  24. doi Persuasive techniques used in television advertisements to market foods to UK children
    Emma J Boyland
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Appetite 58:658-64. 2012
    ..Further studies should incorporate an analysis of the content of websites promoted during food adverts...
  25. doi CNS regulation of appetite
    Joanne A Harrold
    Human Ingestive Behaviour Laboratory, Department of Experimental Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, UK
    Neuropharmacology 63:3-17. 2012
    ..This article is part of a Special Issue entitled 'Central Control of Food Intake'...
  26. ncbi Effects of insulin-induced hypoglycaemia on energy intake and food choice at a subsequent test meal
    Shivani Dewan
    Diabetes and Endocrinology Research Group, University Hospital Aintree, Liverpool, UK
    Diabetes Metab Res Rev 20:405-10. 2004
    ..Hypoglycaemia is assumed to increase food intake, but there is little data on the magnitude or qualitative nature of this effect. We have therefore investigated the effects of insulin-induced hypoglycaemia on food intake at a test meal...
  27. ncbi Food neophobia and 'picky/fussy' eating in children: a review
    Terence M Dovey
    Department of Psychology, Staffordshire University, College Road, Stoke on Trent, Staffordshire ST4 2DE, UK
    Appetite 50:181-93. 2008
    ..Behavioural interventions, focusing on early life exposure, could be developed to attenuate food neophobia and 'picky/fussy' eating in children, so promoting the ready acceptance and independent choice of fruits and vegetables...
  28. doi The extent of food advertising to children on UK television in 2008
    Emma J Boyland
    Department of Experimental Psychology, Institute of Psychology, Health and Society, University of Liverpool, Liverpool, UK
    Int J Pediatr Obes 6:455-61. 2011
    ..To provide the most comprehensive analysis to date of the extent of food advertising on UK television channels popular with young people following regulatory reform of this type of marketing activity...
  29. ncbi Characterization of olanzapine-induced weight gain in rats
    Andrew J Goudie
    Psychology Department, Eleanor Rathbone Building, Liverpool University, Liverpool, UK
    J Psychopharmacol 16:291-6. 2002
    ..However, it remains to be determined how closely rodent models mimic the clinical situation and whether the mechanism(s) involved in the weight gain we have observed are the same as those involved in the clinical use of these drugs...
  30. doi Autoradiographic analysis of ghrelin receptors in the rat hypothalamus
    Joanne A Harrold
    School of Psychology, University of Liverpool, Eleanor Rathbone Building, Bedford Street South, Liverpool L69 7ZA, U K
    Brain Res 1196:59-64. 2008
    ..We suggest that this may relate to the paradigm employed to modify nutritional status in the study or could indicate that peripheral ghrelin is unlikely to be the major source of ghrelin that acts in many hypothalamic sites...
  31. ncbi Orphan G-protein-coupled receptors : strategies for identifying ligands and potential for use in eating disorders
    Joanne A Harrold
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Drugs R D 8:287-99. 2007
    ..Consequently, hypophagic treatments may be of potential benefit in normal, overweight or obese individuals displaying aberrant (out of control) eating behaviour...
  32. doi Stigmatisation of a formerly obese young female
    Sonia A Tucci
    Kissileff Laboratory for the Study of Human Ingestive Behaviour, School of Psychology, University of Liverpool, Liverpool, UK
    Obes Facts 6:433-42. 2013
    ..Since past weight history tends to be disclosed in several contexts, this study aims to investigate whether negative appraisals are gender-specific and if they are modulated by the evaluators' own BMI...
  33. ncbi Adolescence and the diet-dieting disparity: healthy food choice or risky health behaviour?
    Paul J Lattimore
    Department of Psychology, Chester College of Higher Education, UK
    Br J Health Psychol 8:451-63. 2003
    ..It was predicted that dieters would make healthier food choices compared to non-dieters and that measures of eating psychopathology would be associated with food choice...
  34. ncbi A preliminary investigation into the relationship between anabolic-androgenic steroid use and the symptoms of reverse anorexia in both current and ex-users
    Jon C Cole
    Psychology Department, Liverpool University, Liverpool, L69 7ZA, UK
    Psychopharmacology (Berl) 166:424-9. 2003
    ..To establish whether the symptoms of reverse anorexia continue with the cessation of anabolic-androgenic steroid (AAS) use in male body builders...
  35. ncbi Editorial
    Jason C G Halford
    Curr Drug Targets 6:143-4. 2005
  36. ncbi Is there a role for ghrelin and peptide-YY in the pathogenesis of obesity in adults with acquired structural hypothalamic damage?
    Christina Daousi
    University Hospital Aintree, Diabetes and Endocrinology Research Group, Clinical Sciences Center, Longmoor Lane, Liverpool L9 7AL, United Kingdom
    J Clin Endocrinol Metab 90:5025-30. 2005
    ..Obesity is a common sequel to hypothalamic tumors and their treatment, but the underlying mechanisms are not fully established...
  37. ncbi H(1)-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
    Andrew J Goudie
    Neuropsychopharmacology 28:2209; author reply 2210-11. 2003