Hugh Md Gurling

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2
    Irene Guerrini
    Molecular Psychiatry Laboratory, Windeyer Institute for Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London, W1T 4JF, UK
    BMC Genet 6:11. 2005
  2. pmc Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
    H M Gurling
    Molecular Psychiatry Laboratory, Department of Psychiatry and Behavioural Sciences, Windeyer Institute for Medical Sciences, Royal Free and University College London Medical School, London, W1T 4JF, United Kingdom
    Am J Hum Genet 68:661-73. 2001
  3. pmc Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia
    Nicholas J Bass
    Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London, W1T 4JF, UK
    Behav Brain Funct 5:28. 2009
  4. pmc Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia
    Susmita R Datta
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London, W1T 4JF, UK
    Behav Brain Funct 3:50. 2007
  5. pmc Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia
    Hugh M D Gurling
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, United Kingdom
    Arch Gen Psychiatry 63:844-54. 2006
  6. doi request reprint Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence
    G J Lydall
    Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Psychiatry and Behavioural Sciences, Royal Free and University College London, London Medical School, 46 Cleveland Street, London W1T 4JF, UK
    Neurosci Lett 500:162-6. 2011
  7. ncbi request reprint Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample
    Vinay Puri
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Royal Free and University College London Medical School, Windeyer Institute of Medical Sciences, London, W1T 4JF, UK
    Biol Psychiatry 59:195-7. 2006
  8. pmc A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia
    Khalid Choudhury
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, W1T 4JF, UK
    Am J Hum Genet 80:664-72. 2007
  9. ncbi request reprint Genetic linkage analysis of the X chromosome in autism, with emphasis on the fragile X region
    John B Vincent
    Molecular Psychiatry Laboratory, Department of Psychiatry and Behavioural Sciences, Windeyer Institute of Medical Science, University College London, London
    Psychiatr Genet 15:83-90. 2005
  10. ncbi request reprint Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS)
    Irene Guerrini
    Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London W1T 4JF, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 137:17-9. 2005

Collaborators

Detail Information

Publications14

  1. pmc Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2
    Irene Guerrini
    Molecular Psychiatry Laboratory, Windeyer Institute for Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London, W1T 4JF, UK
    BMC Genet 6:11. 2005
    ..In order to confirm a previous finding of linkage to alcoholism on chromosome 1 we have carried out a genetic linkage study...
  2. pmc Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23
    H M Gurling
    Molecular Psychiatry Laboratory, Department of Psychiatry and Behavioural Sciences, Windeyer Institute for Medical Sciences, Royal Free and University College London Medical School, London, W1T 4JF, United Kingdom
    Am J Hum Genet 68:661-73. 2001
    ..Such studies will soon allow the identification of mutations having a direct effect on susceptibility to schizophrenia...
  3. pmc Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia
    Nicholas J Bass
    Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London, W1T 4JF, UK
    Behav Brain Funct 5:28. 2009
    ..abstract:..
  4. pmc Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia
    Susmita R Datta
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, 46 Cleveland Street, London, W1T 4JF, UK
    Behav Brain Funct 3:50. 2007
    ..abstract:..
  5. pmc Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia
    Hugh M D Gurling
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, United Kingdom
    Arch Gen Psychiatry 63:844-54. 2006
    ..There is evidence of linkage to a schizophrenia susceptibility locus on chromosome 8p21-22 found by several family linkage studies...
  6. doi request reprint Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence
    G J Lydall
    Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Psychiatry and Behavioural Sciences, Royal Free and University College London, London Medical School, 46 Cleveland Street, London W1T 4JF, UK
    Neurosci Lett 500:162-6. 2011
    ..This dissociation of effect may reflect the fact that the EEG is a more direct marker of phenotypic GABRA2 expression than the more heterogeneous alcohol dependence phenotype...
  7. ncbi request reprint Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample
    Vinay Puri
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, Royal Free and University College London Medical School, Windeyer Institute of Medical Sciences, London, W1T 4JF, UK
    Biol Psychiatry 59:195-7. 2006
    ..A second Chinese study found a base pair polymorphism at the CAPON gene also associated with schizophrenia...
  8. pmc A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia
    Khalid Choudhury
    Molecular Psychiatry Laboratory, Department of Mental Health Sciences, University College London Medical School, Windeyer Institute of Medical Sciences, London, W1T 4JF, UK
    Am J Hum Genet 80:664-72. 2007
    ..Etiological base-pair changes in FXYD6 or in associated promoter/control regions are likely to cause abnormal function or expression of phosphohippolin and to increase genetic susceptibility to schizophrenia...
  9. ncbi request reprint Genetic linkage analysis of the X chromosome in autism, with emphasis on the fragile X region
    John B Vincent
    Molecular Psychiatry Laboratory, Department of Psychiatry and Behavioural Sciences, Windeyer Institute of Medical Science, University College London, London
    Psychiatr Genet 15:83-90. 2005
    ..1 for a broad phenotype diagnostic model. Thus, this study offers modest support for a susceptibility locus for autism within the Xq27-q28 region. Further genetic investigations of this region are warranted...
  10. ncbi request reprint Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS)
    Irene Guerrini
    Molecular Psychiatry Laboratory, Windeyer Institute of Medical Sciences, Department of Mental Health Sciences, Royal Free and University College London Medical School, 46 Cleveland Street, London W1T 4JF, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 137:17-9. 2005
  11. pmc Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia
    Cathryn M Lewis
    Division of Genetics and Development, Guy s, King s and St Thomas School of Medicine, London, UK
    Am J Hum Genet 73:34-48. 2003
    ..There is greater consistency of linkage results across studies than has been previously recognized. The results suggest that some or all of these regions contain loci that increase susceptibility to schizophrenia in diverse populations...
  12. doi request reprint Genetics of attention-deficit hyperactivity disorder (ADHD)
    Sally I Sharp
    Molecular Psychiatry Laboratory, Research Department of Mental Health Sciences, Windeyer Institute of Medical Sciences, University College London Medical School, 46 Cleveland Street, London W1T 4JF, UK
    Neuropharmacology 57:590-600. 2009
    ....
  13. ncbi request reprint Molecular and genomic studies of IMMP2L and mutation screening in autism and Tourette syndrome
    Erwin Petek
    Institute of Medical Biology and Human Genetics, Medical University of Graz, Harrachgasse 21 8, 8010, Graz, Austria
    Mol Genet Genomics 277:71-81. 2007
    ..Despite the fact that no deleterious mutations in IMMPL2 (other than the inverted duplication identified previously) were identified in either GTS or AD, this gene cannot be excluded as a possible rare cause of either disorder...
  14. ncbi request reprint Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands
    John B Vincent
    Neurogenetics Section, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Am J Med Genet B Neuropsychiatr Genet 129:82-4. 2004
    ..Our own study, screening a larger sample of 196 autism probands, failed to identify any mutations that would affect the coding regions of these genes. Our findings suggest that mutations in these two genes are infrequent in autism...