D Gubb

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs
    D Gubb
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    Genes Dev 13:2315-27. 1999
  2. ncbi Recovery of a marked translocation strain that will facilitate the isolation of balancer chromosomes in the Mediterranean fruit fly, Ceratitis capitata
    D Gubb
    Institute of Molecular Biology and Biotechnology, Research Center of Crete, Foundation for Research and Technology Hellas, Greece
    Genome 41:256-65. 1998
  3. pmc Topological constraints on transvection between white genes within the transposing element TE35B in Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, United Kingdom
    Genetics 146:919-37. 1997
  4. pmc A selective screen to recover chromosomal deletions and duplications in Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, England
    Genetics 119:377-90. 1988
  5. pmc The necrotic gene in Drosophila corresponds to one of a cluster of three serpin transcripts mapping at 43A1.2
    C Green
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, England
    Genetics 156:1117-27. 2000
  6. ncbi Cellular polarity, mitotic synchrony and axes of symmetry during growth. Where does the information come from?
    D Gubb
    Department of Genetics, University of Cambridge, United Kingdom
    Int J Dev Biol 42:369-77. 1998
  7. ncbi Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein
    S Collier
    Department of Genetics, University of Cambridge, UK
    Development 124:4029-37. 1997
  8. pmc A novel transvection phenomenon affecting the white gene of Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, England
    Genetics 126:167-76. 1990
  9. ncbi Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Drosophila melanogaster
    T Davis
    Kennedy Galton Centre, Northwick Park, Harrow, UK
    Hereditas 126:67-75. 1997
  10. pmc Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster
    P Heitzler
    Laboratoire de Genetique Moleculaire des Eucaryotes du CNRS, Unite 184 de Biologie Moleculaire et de Genie Genetique de l INSERM, Faculte de Medicine, Strasbourg, France
    Genetics 135:105-15. 1993

Collaborators

Detail Information

Publications14

  1. pmc The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs
    D Gubb
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    Genes Dev 13:2315-27. 1999
    ..Lack of both pk and sple transcripts gives a phenotype affecting the whole body surface that is similar to those of dishevelled and frizzled (fz) suggesting a functional relationship between pk and fz signaling...
  2. ncbi Recovery of a marked translocation strain that will facilitate the isolation of balancer chromosomes in the Mediterranean fruit fly, Ceratitis capitata
    D Gubb
    Institute of Molecular Biology and Biotechnology, Research Center of Crete, Foundation for Research and Technology Hellas, Greece
    Genome 41:256-65. 1998
    ..These results have implications for the construction and long-term maintenance of genetically modified strains...
  3. pmc Topological constraints on transvection between white genes within the transposing element TE35B in Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, United Kingdom
    Genetics 146:919-37. 1997
    ..Similarly, breakpoints immediately proximal or distal to both w genes give partial suppression. This transvection-dependent downregulation of w genes may result from mis-activation of the X-chromosome dosage compensation mechanism...
  4. pmc A selective screen to recover chromosomal deletions and duplications in Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, England
    Genetics 119:377-90. 1988
    ..Such aberration breakpoints can be genetically mapped, as synthetic deletions, and then used as transposon-tagged sites for the recovery of genomic clones...
  5. pmc The necrotic gene in Drosophila corresponds to one of a cluster of three serpin transcripts mapping at 43A1.2
    C Green
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, England
    Genetics 156:1117-27. 2000
    ..Absence of Spn43Ac, however, gives a clear phenotype, which will allow a mutational analysis of critical features of the molecular structure of serpins...
  6. ncbi Cellular polarity, mitotic synchrony and axes of symmetry during growth. Where does the information come from?
    D Gubb
    Department of Genetics, University of Cambridge, United Kingdom
    Int J Dev Biol 42:369-77. 1998
    ..The polarity patterns observed in adult cuticular bristles and hairs reflect accurate control of the shape of terminally differentiating cells rather than fine-grained positional information...
  7. ncbi Drosophila tissue polarity requires the cell-autonomous activity of the fuzzy gene, which encodes a novel transmembrane protein
    S Collier
    Department of Genetics, University of Cambridge, UK
    Development 124:4029-37. 1997
    ..Expression of the fy transcript is developmentally regulated and peaks sharply at the time of wing cell pre-hair initiation...
  8. pmc A novel transvection phenomenon affecting the white gene of Drosophila melanogaster
    D Gubb
    Department of Genetics, University of Cambridge, England
    Genetics 126:167-76. 1990
    ..This effect of rearrangements has been used as the basis for a screen, gamma-ray induced aberrations with at least one breakpoint opposite the TE site were recovered by their suppression of the zeste phenotype...
  9. ncbi Genetic and phenotypic analysis of the genes of the elbow-no-ocelli region of chromosome 2L of Drosophila melanogaster
    T Davis
    Kennedy Galton Centre, Northwick Park, Harrow, UK
    Hereditas 126:67-75. 1997
    ..Alleles of el and noc show partial failure of complementation, heterozygotes having weak el or weak noc phenotypes. Alleles of both these genes interact with the antimorphic noc allele Sco...
  10. pmc Genetic and cytogenetic analysis of the 43A-E region containing the segment polarity gene costa and the cellular polarity genes prickle and spiny-legs in Drosophila melanogaster
    P Heitzler
    Laboratoire de Genetique Moleculaire des Eucaryotes du CNRS, Unite 184 de Biologie Moleculaire et de Genie Genetique de l INSERM, Faculte de Medicine, Strasbourg, France
    Genetics 135:105-15. 1993
    ..In addition 19 novel lethal complementation groups and two semi-lethal complementation groups with morphogenetic escaper phenotypes are described...
  11. ncbi A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster
    D Gubb
    J Embryol Exp Morphol 68:37-57. 1982
    ..The mutants affect several independent functions. The possible wild-type function of the loci in polarity formation is discussed...
  12. ncbi Spontaneous excision of a large composite transposable element of Drosophila melanogaster
    W Chia
    Nature 316:81-3. 1985
    ..These residual sequences share homology with the FB family. Furthermore, despite their imprecise nature, all these spontaneous excisions restore a wild-type noc+ phenotype...
  13. ncbi Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila
    E A Levashina
    UPR 9022 CNRS, Institut de Biologie Moleculaire et Cellulaire, 15 rue Rene Descartes, Strasbourg 67084, France
    Science 285:1917-9. 1999
    ..Hence, Spn43Ac negatively regulates the Toll signaling pathway, and Toll does not function as a pattern recognition receptor in the Drosophila host defense...
  14. ncbi The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family
    J Chae
    Department of Life Science, Kwangju Institute of Science and Technology K JIST, Kwangju, Korea
    Development 126:5421-9. 1999
    ..This suggests that Stan functions in signal reception, perhaps together with Fz...