Affiliation: University College London
- Clinical review: Evidence-based perioperative medicine?Hanif Meeran
Centre for Anaesthesia, University College London, UK
Crit Care 9:81-5. 2005..Conversely a high level of evidence supports other interventions that have not been so widely adopted. This may be due to concerns about limitations in the design and conduct of some of the clinical trials...
- Design and conduct of Caudwell Xtreme Everest: an observational cohort study of variation in human adaptation to progressive environmental hypoxiaDenny Z H Levett
Centre for Altitude Space and Extreme Environment Medicine, UCL Institute of Human Health and Performance, First Floor, Charterhouse Building, UCL Archway Campus, Highgate Hill, London, N19 5LW, UK
BMC Med Res Methodol 10:98. 2010..The aim of this study was to describe the spectrum of adaptive responses in humans exposed to graded EHH and identify factors (physiological and genetic) associated with inter-individual variation in these responses...
- Ketamine for emergency anaesthesia at very high altitude (4243 m above sea-level)M P W Grocott
Centre for Altitude, Space, and Extreme Environment Medicine, UCL Institute of Human Health and Performance, Ground Floor, Charterhouse Building, UCL Archway Campus, Highgate Hill, London N19 5LW, UK
Anaesthesia 62:959-62. 2007..The availability of airway management equipment and the skills to use them may significantly reduce the risks associated with anaesthetic administration at very high altitude...
- Caudwell xtreme Everest expeditionMichael P W Grocott
High Alt Med Biol 11:133-7. 2010..Unique arterial blood gas values were obtained from 4 subjects at 8400 m during descent from the summit of Everest. Arterial blood gas and microcirculatory blood flow data are discussed in detail...
- Arterial blood gases and oxygen content in climbers on Mount EverestMichael P W Grocott
Centre for Altitude, Space, and Extreme Environment Medicine, University College London Institute of Human Health and Performance, London, United Kingdom
N Engl J Med 360:140-9. 2009..We performed direct field measurements of arterial blood gases in climbers breathing ambient air on Mount Everest...
- The Postoperative Morbidity Survey was validated and used to describe morbidity after major surgeryM P W Grocott
Surgical Outcome Research Centre, University College London Hospitals, London, W1T 3AA, UK
J Clin Epidemiol 60:919-28. 2007..To describe the reliability and validity of the Postoperative Morbidity Survey (POMS). To describe the level and pattern of short-term postoperative morbidity after major elective surgery using the POMS...
- High-altitude physiology and pathophysiology: implications and relevance for intensive care medicineMichael Grocott
Centre for Altitude, Space and Extreme Environment Medicine CASE Medicine, UCL Institute of Human Health and Performance, UCL Archway Campus, Highgate Hill, London, UK
Crit Care 11:203. 2007..The present review explores the idea that human responses to the hypoxia of high altitude may be used as a means of exploring elements of the pathophysiology of critical illness...
- Resuscitation from hemorrhagic shock using rectally administered fluids in a wilderness environmentMichael P W Grocott
Centre for Aviation Space and Extreme Environment Medicine University College London, Room 103, 1st Floor Crosspiece, Middlesex Hospital, Mortimer Street, London, W1A 3AA, UK
Wilderness Environ Med 16:209-11. 2005..The subject was a 21-year-old Nepali man who had experienced a major upper gastrointestinal hemorrhage...
- Systematic review of paediatric alert criteria for identifying hospitalised children at risk of critical deteriorationSusan M Chapman
UCL Institute of Child Health, London, UK
Intensive Care Med 36:600-11. 2010....
- Parent stress levels during children's hospital recovery after congenital heart surgeryLinda S Franck
UCL Institute of Child Health, London, UK
Pediatr Cardiol 31:961-8. 2010..Better identification of parents at risk for high stress and specific interventions to improve parental support and coping are needed...
- Physiology, pharmacology, and rationale for colloid administration for the maintenance of effective hemodynamic stability in critically ill patientsAndre Vercueil
Department of Anaesthetics and Intensive Care, Royal Brompton and Harefield NHS Trust, London, UK
Transfus Med Rev 19:93-109. 2005..9% saline as a resuscitation fluid. The choice of clinical endpoints to guide dosage (infused volume) of colloids is probably therefore more important than the choice between individual products...
- Perioperative fluid management and clinical outcomes in adultsMichael P W Grocott
Centre for Anaesthesia, University College London, United Kingdom
Anesth Analg 100:1093-106. 2005..In this article, we review the available fluid types and strategies of fluid administration and discuss their relationship to clinical outcomes in adults...