P D Griffiths

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. ncbi request reprint MR imaging of patients with localisation-related seizures: initial experience at 3.0T and relevance to the NICE guidelines
    P D Griffiths
    Section of Radiology, University of Sheffield, Sheffield, UK
    Clin Radiol 60:1090-9. 2005
  2. pmc MRI of the foetal brain using a rapid 3D steady-state sequence
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Br J Radiol 86:20130168. 2013
  3. pmc The use of in utero MRI to supplement ultrasound in the foetus at high risk of developmental brain or spine abnormality
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Br J Radiol 85:e1038-45. 2012
  4. doi request reprint The use of in utero MR imaging to delineate developmental brain abnormalities in multifetal pregnancies
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    AJNR Am J Neuroradiol 33:359-65. 2012
  5. ncbi request reprint Neurofibromatosis bright objects in children with neurofibromatosis type 1: a proliferative potential?
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, Sheffield, United Kingdom
    Pediatrics 104:e49. 1999
  6. ncbi request reprint MR imaging of the fetal brain and spine: a maturing technology
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, United Kingdom
    Ann Acad Med Singapore 32:483-9. 2003
  7. doi request reprint Effects of failed commissuration on the septum pellucidum and fornix: implications for fetal imaging
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Neuroradiology 51:347-56. 2009
  8. doi request reprint Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Neuroradiology 51:337-45. 2009
  9. pmc In utero magnetic resonance imaging for brain and spinal abnormalities in fetuses
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF
    BMJ 331:562-5. 2005
  10. ncbi request reprint MR imaging of recent non-traumatic intracranial hemorrhage: early experience at 3 T
    Paul D Griffiths
    Academic Unit of Radiology, Floor C, Royal Hallamshire Hospital, Sheffield, UK
    Neuroradiology 48:247-54. 2006

Collaborators

Detail Information

Publications111 found, 100 shown here

  1. ncbi request reprint MR imaging of patients with localisation-related seizures: initial experience at 3.0T and relevance to the NICE guidelines
    P D Griffiths
    Section of Radiology, University of Sheffield, Sheffield, UK
    Clin Radiol 60:1090-9. 2005
    ..Although MR is acknowledged to be a reliable way of detecting pathology in people with epilepsy there is a dearth of information studying the health economics of imaging epilepsy in relation to patient management and outcomes...
  2. pmc MRI of the foetal brain using a rapid 3D steady-state sequence
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Br J Radiol 86:20130168. 2013
    ..We have also made assessments of the estimates of energy deposition using those methods...
  3. pmc The use of in utero MRI to supplement ultrasound in the foetus at high risk of developmental brain or spine abnormality
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Br J Radiol 85:e1038-45. 2012
    ..In this paper, we test the hypothesis that in utero MRI of the foetal brain in high-risk pregnancies will detect abnormalities not shown by ultrasound at a rate that justifies its use in clinical practice...
  4. doi request reprint The use of in utero MR imaging to delineate developmental brain abnormalities in multifetal pregnancies
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    AJNR Am J Neuroradiol 33:359-65. 2012
    ..The hypothesis tested in this study was that iuMR performed in multifetal pregnancies will show additional information about fetal CNS abnormalities in a similar proportion of cases when compared with singleton pregnancies...
  5. ncbi request reprint Neurofibromatosis bright objects in children with neurofibromatosis type 1: a proliferative potential?
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, Sheffield, United Kingdom
    Pediatrics 104:e49. 1999
    ..We have paid particular attention to the development of tumors in these areas of abnormality...
  6. ncbi request reprint MR imaging of the fetal brain and spine: a maturing technology
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, United Kingdom
    Ann Acad Med Singapore 32:483-9. 2003
    ..We describe the background and refinements to a 3-year research study designed to evaluate the role of magnetic resonance (MR) imaging in detecting and defining abnormalities of the fetal central nervous system in utero...
  7. doi request reprint Effects of failed commissuration on the septum pellucidum and fornix: implications for fetal imaging
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Neuroradiology 51:347-56. 2009
    ..In this article, we discuss the effects of failed commissuration on the midline structures. We highlight some of the misconceptions of this process that may lead to misdiagnosis of agenesis of the corpus callosum in utero...
  8. doi request reprint Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Neuroradiology 51:337-45. 2009
    ..In this article, we consider the normal appearances of the corpus callosum, septum pellucidum and fornix as shown on MR imaging in normal and near-normal states...
  9. pmc In utero magnetic resonance imaging for brain and spinal abnormalities in fetuses
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF
    BMJ 331:562-5. 2005
  10. ncbi request reprint MR imaging of recent non-traumatic intracranial hemorrhage: early experience at 3 T
    Paul D Griffiths
    Academic Unit of Radiology, Floor C, Royal Hallamshire Hospital, Sheffield, UK
    Neuroradiology 48:247-54. 2006
    ..0 T may offer opportunities for significant changes in patient management. We present our experiences of using 3.0 T MR angiography in 27 patients with acute or early subacute ICH...
  11. doi request reprint Distribution and conspicuity of intracranial abnormalities on MR imaging in adults with tuberous sclerosis complex: A comparison of sequences including ultrafast T2-weighted images
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom
    Epilepsia 50:2605-10. 2009
    ..This study evaluates which magnetic resonance (MR) sequences show the pathology best and to see if "ultrafast" sequences can show the pathology robustly...
  12. doi request reprint A prospective study of fetuses with isolated ventriculomegaly investigated by antenatal sonography and in utero MR imaging
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    AJNR Am J Neuroradiol 31:106-11. 2010
    ....
  13. ncbi request reprint Imaging the fetal spine using in utero MR: diagnostic accuracy and impact on management
    Paul D Griffiths
    Academic Unit of Radiology, Royal Hallamshire Hospital, University of Sheffield, Glossop Road, Sheffield, S10 2JF, UK
    Pediatr Radiol 36:927-33. 2006
    ..In-utero MR imaging (iuMR) has entered the clinical arena during the last decade. It is used mainly for imaging fetal brain abnormalities...
  14. doi request reprint Fetuses with ventriculomegaly diagnosed in the second trimester of pregnancy by in utero MR imaging: what happens in the third trimester?
    P D Griffiths
    Academic Unit of Radiology, University of Sheffield, United Kingdom
    AJNR Am J Neuroradiol 32:474-80. 2011
    ..In particular, we wished to study the hypothesis that third-trimester fetal MR imaging studies would not show extra brain abnormalities compared with the second-trimester studies in this group...
  15. ncbi request reprint The use of MR imaging and spectroscopy of the brain in children investigated for developmental delay: what is the most appropriate imaging strategy?
    Paul D Griffiths
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    Eur Radiol 21:1820-30. 2011
    ..Our study was performed as part of a continuing audit process to optimise our MR protocol and case selection...
  16. ncbi request reprint Assessment of cerebral haemodynamics and vascular reserve in patients with symptomatic carotid artery occlusion: an integrated MR method
    P D Griffiths
    Unit of Academic Radiology, Floor C, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK
    Neuroradiology 47:175-82. 2005
    ..We believe that demonstration of both macroscopic vascular anatomy and microvascular reserve is important when assessing patients with possible low-flow states and the described method is a robust means of obtaining that data...
  17. ncbi request reprint In vivo measurement of cerebral blood flow: a review of methods and applications
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, UK
    Vasc Med 6:51-60. 2001
    ..Applications of magnetic resonance and X-ray computed tomographic methods are reviewed and illustrated by examples from the authors' radiological practice...
  18. ncbi request reprint Differential growth rates of the cerebellum and posterior fossa assessed by post mortem magnetic resonance imaging of the fetus: implications for the pathogenesis of the chiari 2 deformity
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, UK
    Acta Radiol 45:236-42. 2004
    ..To evaluate post mortem magnetic resonance imaging of the fetus to provide data on the rate of growth of the cerebellum, bony posterior fossa, supratentorial bony compartment and cerebrum...
  19. ncbi request reprint Post-mortem MRI as an adjunct to fetal or neonatal autopsy
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, Sheffield S10 2JF, UK
    Lancet 365:1271-3. 2005
    ..This information is mainly obtained from autopsies, but the number of parents agreeing to autopsy has dropped, which has prompted the search for adjuncts to autopsy...
  20. pmc Cerebellar abnormalities on proton MR spectroscopy in gluten ataxia
    I D Wilkinson
    Academic Unit of Radiology, University of Sheffield, Sheffield, England
    J Neurol Neurosurg Psychiatry 76:1011-3. 2005
    ..These data support the hypothesis that cerebellar neuronal physiology differs between patients with gluten ataxia and healthy controls...
  21. ncbi request reprint A method of generalized projections (MGP) ghost correction algorithm for interleaved EPI
    K J Lee
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
    IEEE Trans Med Imaging 23:839-48. 2004
    ....
  22. ncbi request reprint First-line investigation of acute intracerebral hemorrhage using dynamic magnetic resonance angiography
    A L Evans
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Acta Radiol 46:625-30. 2005
    ..To report the initial experience of magnetic resonance (MR) digital subtraction angiography (MR-DSA) in the dynamic assessment of the cerebral circulation in acute non-traumatic intracerebral hemorrhage (ICH)...
  23. ncbi request reprint Proton spectroscopy and imaging at 3T in ataxia-telangiectasia
    L I Wallis
    Academic Unit of Radiology, The University of Sheffield, Sheffield, United Kingdom
    AJNR Am J Neuroradiol 28:79-83. 2007
    ..We used MR spectroscopy to test the hypothesis that cerebellar metabolism in A-T patients would be abnormal relative to healthy controls...
  24. ncbi request reprint Cerebral arteriovenous malformations: comparison of novel magnetic resonance angiographic techniques and conventional catheter angiography
    D J Warren
    Section of Academic Radiology, University of Sheffield, England
    Neurosurgery 48:973-82; discussion 982-3. 2001
    ..MR DSA shows promise as a noninvasive method for dynamic angiography but is presently restricted by limitations in both temporal and spatial resolution...
  25. ncbi request reprint Comparison of ultrasound and magnetic resonance imaging in 100 singleton pregnancies with suspected brain abnormalities
    E H Whitby
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, UK
    BJOG 111:784-92. 2004
    ..To compare the diagnostic accuracy of the current reference standard-ultrasound with in utero magnetic resonance imaging, in a selected group of patients...
  26. ncbi request reprint Corroboration of in utero MRI using post-mortem MRI and autopsy in foetuses with CNS abnormalities
    E H Whitby
    Section of Academic Radiology, Department of MRI, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK
    Clin Radiol 59:1114-20. 2004
    ....
  27. ncbi request reprint Stereotactic radiosurgery for brain arteriovenous malformations: quantitative MR assessment of nidal response at 1 year and angiographic factors predicting early obliteration
    S Nagaraja
    Section of Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, England, UK
    Neuroradiology 48:821-9. 2006
    ....
  28. ncbi request reprint Imaging findings and referral outcomes of rapid assessment stroke clinics
    E Widjaja
    Radiology Department, Royal Hallamshire Hospital, Sheffield, UK
    Clin Radiol 60:1076-82. 2005
    ..In this report we review imaging findings and clinical outcomes of patients proceeding to the carotid surgery programme...
  29. ncbi request reprint Simultaneous multislice imaging with slice-multiplexed RF pulses
    K J Lee
    Academic Unit of Radiology, University of Sheffield, UK
    Magn Reson Med 54:755-60. 2005
    ..There is also a concomitant increase in the minimum TR of the sequence. The method is demonstrated with phantom and in vivo images using gradient-echo and spin-echo versions...
  30. ncbi request reprint Assessment of sulcation of the fetal brain in cases of isolated agenesis of the corpus callosum using in utero MR imaging
    D J Warren
    Radiology Department, Royal Hallamshire Hospital, Sheffield NHS Teaching Hospitals Trust, Glossop Road, Sheffield, UK
    AJNR Am J Neuroradiol 31:1085-90. 2010
    ..In this paper we sought to confirm whether delayed sulcation is found in fetuses with isolated agenesis of the corpus callosum as judged by in utero MR imaging...
  31. pmc Detection of subarachnoid haemorrhage with magnetic resonance imaging
    P Mitchell
    Department of Neurosurgery, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    J Neurol Neurosurg Psychiatry 70:205-11. 2001
    ..To measure the sensitivity and specificity of five MRI sequences to subarachnoid haemorrhage...
  32. ncbi request reprint The effects of dehydration on brain volume -- preliminary results
    J M Dickson
    Department of Biomedical Science, The University of Sheffield, Sheffield, UK
    Int J Sports Med 26:481-5. 2005
    ..932, p=0.007). The changes in ventricular volume caused by dehydration were much larger than those seen in day-to-day fluctuations in a normally hydrated healthy control subject...
  33. doi request reprint Corpus callosum morphology and microstructure assessed using structural MR imaging and diffusion tensor imaging: initial findings in adults with neurofibromatosis type 1
    E L Wignall
    Academic Unit of Radiology, University of Sheffield, Sheffield, UK
    AJNR Am J Neuroradiol 31:856-61. 2010
    ..The purpose of this study was to determine if the CC in adults with NF-1 differed from that in matched controls by using DTI and volumetric imaging...
  34. ncbi request reprint The value of in-utero magnetic resonance imaging in ultrasound diagnosed foetal isolated cerebral ventriculomegaly
    J E Morris
    Section of Academic Radiology, Royal Hallamshire Hospital, University of Sheffield, UK
    Clin Radiol 62:140-4. 2007
    ..To assess whether, in such cases, ventricular morphology is a useful indicator for the underlying pathology, as has recently been suggested...
  35. ncbi request reprint Post-mortem MRI of the foetal spine and spinal cord
    E Widjaja
    Academic Section of Radiology, Sheffield Children s Hospital, Sheffield, UK
    Clin Radiol 61:679-85. 2006
    ..To compare the findings of post-mortem magnetic resonance imaging (MRI) of the foetal spine with autopsy with a view to using post-mortem MRI as an alternative or adjunct to autopsy, particularly in foetal and neonatal cases...
  36. doi request reprint MR spectroscopy and atrophy in Gluten, Friedreich's and SCA6 ataxias
    M Hadjivassiliou
    Department of Neurology, Royal Hallamshire Hospital, Sheffield, UK
    Acta Neurol Scand 126:138-43. 2012
    ..Previous work using proton MR spectroscopy ((1)H-MRS) of the cerebellum in the ataxias suggested that (1)H-MRS abnormalities and atrophy do not necessarily occur concurrently...
  37. pmc 3.0 T MRI of 2000 consecutive patients with localisation-related epilepsy
    I J Craven
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Br J Radiol 85:1236-42. 2012
    ..We set out to review the detection rate of radiological abnormalities found by imaging patients with localised seizures using a high-resolution 3.0 T epilepsy protocol...
  38. ncbi request reprint Method of generalized projections algorithm for image-based reduction of artifacts in radial imaging
    K J Lee
    Academic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom
    Magn Reson Med 54:246-50. 2005
    ..In phantom experiments, MGP performed better than magnitude filtered backprojection and anti-parallel projections correction...
  39. ncbi request reprint Misrepresentation of surface rendering of pediatric brain malformations performed following spatial normalization
    L I Wallis
    Academic Unit of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Acta Radiol 47:1094-9. 2006
    ..To evaluate the effects of spatial normalization on volume rendering in cases of pediatric brain malformation...
  40. ncbi request reprint Normal fetal lumbar spine on postmortem MR imaging
    E Widjaja
    Academic Section of Radiology, University of Sheffield, Sheffield, United Kingdom
    AJNR Am J Neuroradiol 27:553-9. 2006
    ..The aim of this study is to describe the MR imaging appearances of normal development of the fetal spine at different gestational ages...
  41. ncbi request reprint Brain arteriovenous malformations: measurement of nidal volume using a combination of static and dynamic magnetic resonance angiography techniques
    S Nagaraja
    Academic Radiology Section, Royal Hallamshire Hospital, University of Sheffield, Glossop Road, Sheffield, S10 2JF, UK
    Neuroradiology 47:387-92. 2005
    ..The results showed an excellent correlation between MRA and CA measurement of both maximum linear dimension and AVM nidus volume...
  42. ncbi request reprint Proton MR spectroscopy of cortical tubers in adults with tuberous sclerosis complex
    W Mukonoweshuro
    Department of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    AJNR Am J Neuroradiol 22:1920-5. 2001
    ..The reduced NA/Cr ratio is probably due to reduced levels of NA, most likely caused by the presence of immature neurons and glia in tubers that do not express NA, or by the presence of gliosis, a known histologic component of tubers...
  43. ncbi request reprint Multimodality MR imaging depiction of hemodynamic changes and cerebral ischemia in subarachnoid hemorrhage
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, Sheffield, England
    AJNR Am J Neuroradiol 22:1690-7. 2001
    ..MR imaging is a simple noninvasive method of assessing cerebral blood flow and its complications in SAH. It can be performed in a clinical environment...
  44. ncbi request reprint Ultrafast magnetic resonance imaging of central nervous system abnormalities in utero in the second and third trimester of pregnancy: comparison with ultrasound
    E Whitby
    University of Sheffield, Section of Academic Radiology, Royal Hallamshire Hospital, UK
    BJOG 108:519-26. 2001
    ....
  45. ncbi request reprint Measurements and modeling of long range 3He diffusion in the lung using a "slice-washout" method
    Stanislao Fichele
    Academic Unit of Radiology, The University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    J Magn Reson 174:28-33. 2005
    ..The results yield values of the order 0.034 cm2 s(-1), which are nearly an order of magnitude smaller than those reported by PGSE measurements at shorter diffusion times...
  46. doi request reprint Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus
    D Selvarajah
    Diabetes Research Unit, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK
    Diabetologia 51:2088-92. 2008
    ..Our aim was to use in vivo proton magnetic resonance specroscopy (H-MRS) in patients with DPN in order to assess the neuro-chemical status of the thalamus, which acts as the gateway to the brain for somatosensory information...
  47. doi request reprint Discrepancy in reporting among specialist registrars and the role of a paediatric neuroradiologist in reporting paediatric CT head examinations
    S Nagaraja
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Clin Radiol 64:891-6. 2009
    ..To investigate which were the commonly missed abnormalities and the consequences for teaching purposes. To investigate the role of a specialist consultant neuroradiologist in reporting paediatric head computed tomography examinations...
  48. doi request reprint Management of isolated syringomyelia in the paediatric population--a review of imaging and follow-up in a single centre
    R N Joseph
    Department of Radiology, Sheffield Children s Hospital, Sheffield, South Yorkshire, UK
    Br J Neurosurg 27:683-6. 2013
    ..To assess the natural history of isolated syringomyelia in children...
  49. ncbi request reprint Imaging of haemorrhagic stroke
    N Hoggard
    Academic Department of Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    Clin Radiol 57:957-68. 2002
    ..MR in addition offers pathophysiological information that can help with assessment of both the aetiology of and complications arising from both SAH and intra-parenchymal haemorrhage...
  50. ncbi request reprint Brain MR perfusion imaging in humans
    P D Griffiths
    Section of Academic Radiology, University of Sheffield, Sheffield, UK
    Acta Radiol 42:555-9. 2001
    ..CONCLUSION: Four-mm slice thickness perfusion imaging can be performed with high-concentration gadolinium in the human brain and we discuss the advantages of this...
  51. ncbi request reprint Magnetic resonance imaging with stepped B(0) fields
    K J Lee
    Department of Academic Radiology, University of Sheffield, Sheffield, UK
    Magn Reson Imaging 21:625-9. 2003
    ..The principle is illustrated using simple coil designs which introduce up to two steps into the main B(0) field. Phantoms placed in each uniform region were successfully imaged simultaneously with no aliasing...
  52. ncbi request reprint Sequential dynamic gadolinium magnetic resonance perfusion-weighted imaging: effects on transit time and cerebral blood volume measurements
    P D Griffiths
    Unit of Academic Radiology, Royal Hallamshire Hospital, Sheffield, United Kingdom
    Acta Radiol 47:1079-84. 2006
    ..To evaluate if two gadolinium perfusion studies can be performed during the same table occupancy without degradation of the derived data in the second study...
  53. ncbi request reprint Post-mortem fetal MRI: what do we learn from it?
    E H Whitby
    Section of Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Eur J Radiol 57:250-5. 2006
    ....
  54. ncbi request reprint Thunderclap headache: presentation of intracranial sinus thrombosis?
    E Widjaja
    Department of Radiology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Clin Radiol 58:648-52. 2003
  55. ncbi request reprint Neurovascular MRI with dynamic contrast-enhanced subtraction angiography
    S C Coley
    Department of Radiology, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK
    Neuroradiology 45:843-50. 2003
    ..As time-resolved techniques become more sophisticated and 3D acquisitions can be obtained with high isotropic spatial resolution we may start to see the demise of catheter angiography as a diagnostic procedure...
  56. ncbi request reprint The imaging of ischaemic stroke
    N Hoggard
    Academic Department of Radiology, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK
    Clin Radiol 56:171-83. 2001
    ..This can also be achieved with CT. This review article discusses the imaging of ischaemic stroke, relating the pathophysiology of stroke to it. It deals separately in more detail with these newer MR techniques...
  57. ncbi request reprint Frequency and natural history of subdural haemorrhages in babies and relation to obstetric factors
    E H Whitby
    Section of Academic Radiology, University of Sheffield, Sheffield, UK
    Lancet 363:846-51. 2004
    ....
  58. ncbi request reprint Magnetic resonance perfusion imaging in malformations of cortical development
    E Widjaja
    Academic Section of Radiology, University of Sheffield, Sheffield, United Kingdom
    Acta Radiol 48:907-17. 2007
    ..Malformations of cortical development vary in neuronal maturity and level of functioning...
  59. ncbi request reprint The nonspecific nature of proton spectroscopy in brain masses in children: a series of demyelinating lesions
    H G Pandya
    Academic Unit of Radiology, Floor C, Royal Hallamshire Hospital, Sheffield, UK
    Neuroradiology 47:955-9. 2005
    ..We reiterate that spectroscopic appearances are nonspecific and spectroscopic data should be evaluated in the light of concurrent imaging features and the clinical presentation...
  60. ncbi request reprint The high incidence and bioethics of findings on magnetic resonance brain imaging of normal volunteers for neuroscience research
    N Hoggard
    University of Sheffield, Sheffield, UK
    J Med Ethics 35:194-9. 2009
    ..Yet the implications for the individuals involved may be profound. Should all participants have review of their imaging by an expert and who should be informed?..
  61. ncbi request reprint Diffusion tensor imaging for the assessment of upper motor neuron integrity in ALS
    J M Graham
    Academic Unit of Radiology, University of Sheffield, UK
    Neurology 63:2111-9. 2004
    ....
  62. ncbi request reprint Proton magnetic resonance spectroscopy of brain lesions in children with neurofibromatosis type 1
    I D Wilkinson
    Section of Academic Radiology, University of Sheffield, Sheffield, England, UK
    Magn Reson Imaging 19:1081-9. 2001
    ..05). This cross-sectional data suggests that proton spectroscopy can aid differentiating between NBO and brain (non-optic/hypothalamic) glioma. Typical NBO have different short echo-time spectroscopic appearances compared to normal brain...
  63. ncbi request reprint Motor functional MRI for pre-operative and intraoperative neurosurgical guidance
    I D Wilkinson
    Academic Unit of Radiology, University of Sheffield, Sheffield S10 2JF, UK
    Br J Radiol 76:98-103. 2003
    ..This observation is reinforced by the fact that no patients suffered permanent neurological deficit after radical tumour debulking (surgical estimates >90% tumour resection)...
  64. doi request reprint Dimensions and ossification of the normal anterior cranial fossa in children
    David C Hughes
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, United Kingdom
    AJNR Am J Neuroradiol 31:1268-72. 2010
    ..The purpose of this study was to ascertain the age at which the anterior cranial fossa is fully ossified as assessed on CT examinations...
  65. doi request reprint Role of imaging in the diagnosis of acute bacterial meningitis and its complications
    D C Hughes
    Department of Radiology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Postgrad Med J 86:478-85. 2010
    ..Diffusion weighted imaging (DWI) and magnetic resonance spectroscopy (MRS) are useful to distinguish abscess from other ring enhancing lesions...
  66. pmc Idiopathic generalised epilepsy: a pilot study of memory and neuronal dysfunction in the temporal lobes, assessed by magnetic resonance spectroscopy
    J M Dickson
    Department of Biomedical Science, University of Sheffield, Sheffield, UK
    J Neurol Neurosurg Psychiatry 77:834-40. 2006
    ..IGE is therefore ideal for investigations on the effects of seizure activity on memory and cognition. Aim and..
  67. doi request reprint Magnetic resonance imaging of epilepsy at 3 Tesla
    I Craven
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Clin Radiol 66:278-86. 2011
    ..5T. This article reviews the imaging findings of many of the common diseases that can cause epilepsy...
  68. ncbi request reprint Intracranial MR venography in children: normal anatomy and variations
    E Widjaja
    Department of Radiology, Royal Hallamshire Hospital, University of Sheffield, Sheffield, England
    AJNR Am J Neuroradiol 25:1557-62. 2004
    ..Little information is available regarding the anatomy of the intracranial veins and sinuses that can be shown on MR venograms of children. The aim of this study was to determine the normal venous anatomy and anatomic variants...
  69. ncbi request reprint Fast two-dimensional MR imaging by multiple acquisition with micro B(0) array (MAMBA)
    K J Lee
    Department of Academic Radiology, University of Sheffield, Sheffield, United Kingdom
    Magn Reson Imaging 20:119-25. 2002
    ..The results are promising, with the spectra showing generally good resolution between peaks, enabling localisation in up to half the pixels. Technical difficulties are discussed and possible applications are outlined...
  70. ncbi request reprint A stereoscope for image-guided surgery
    P Mitchell
    Department of Neurosurgery, Royal Hallamshire Hospital Sheffield, UK
    Br J Neurosurg 16:261-6; discussion 267-8. 2002
    ..The instrument was used in six cases. A lateral accuracy of 10-15 mm was achieved and a depth accuracy of 5-10 mm...
  71. ncbi request reprint Diabetic neuropathic pain in a leg amputated 44 years previously
    S M Rajbhandari
    Diabetes Centre, Royal Hallamshire Hospital, Sheffield, UK
    Pain 83:627-9. 1999
    ....
  72. ncbi request reprint Image-based EPI ghost correction using an algorithm based on projection onto convex sets (POCS)
    K J Lee
    Department of Academic Radiology, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK
    Magn Reson Med 47:812-7. 2002
    ..The method is tested on spin-echo EPI data. The results show that the method is robust and remarkably effective, reducing the N/2 ghost to a level nearly comparable to that achieved with reference scans...
  73. ncbi request reprint MR imaging of the lungs with hyperpolarized helium-3 gas transported by air
    J M Wild
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, UK
    Phys Med Biol 47:N185-90. 2002
    ..In this study, the feasibility of transporting large quantities of HP gas for in vivo MR imaging from a remote production facility in Mainz, Germany, by airfreight to Sheffield, UK, was successfully demonstrated...
  74. ncbi request reprint k-space filtering in 2D gradient-echo breath-hold hyperpolarized 3He MRI: spatial resolution and signal-to-noise ratio considerations
    Jim M Wild
    Section of Academic Radiology, Royal Hallamshirw Hospital, University of Sheffield, Sheffield, UK
    Magn Reson Med 47:687-95. 2002
    ..A half-Fourier approach potentially offers increased SNR through the use of higher flip angles without compromising the spatial resolution, which is comparable to that achieved with sequential encoding...
  75. ncbi request reprint Finite-difference simulations of 3He diffusion in 3D alveolar ducts: comparison with the "cylinder model"
    Stanislao Fichele
    Academic Unit of Radiology, The University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    Magn Reson Med 52:917-20. 2004
    ..The simulations also demonstrated that the measurement of the longitudinal ADC (along the alveolar ducts) should be sensitive to early emphysematous changes, whereas the measured radii should be far less sensitive...
  76. doi request reprint MRI assessment of basal ganglia iron deposition in Parkinson's disease
    Lauren I Wallis
    Academic Unit of Radiology, The University of Sheffield, and Department of Clinical Neurology, Royal Hallamshire Hospital, Sheffield, United Kingdom
    J Magn Reson Imaging 28:1061-7. 2008
    ..To estimate the levels of basal ganglia iron levels in Parkinson's disease (PD) using the PRIME MR sequence at 3.0 Tesla, in relation to patients' motor symptom severity...
  77. ncbi request reprint Cerebellar volume and cerebellar metabolic characteristics in adults with dyslexia
    Suzanna K Laycock
    Department of Psychology, University of Sheffield, Sheffield, England, UK
    Ann N Y Acad Sci 1145:222-36. 2008
    ..Although it is difficult to interpret the volumetric and spectroscopic results unambiguously, taken together they suggest two possible interpretations: excessive connectivity or abnormal myelination...
  78. ncbi request reprint Investigating 3He diffusion NMR in the lungs using finite difference simulations and in vivo PGSE experiments
    Stanislao Fichele
    Academic Unit of Radiology, The University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, England, UK
    J Magn Reson 167:1-11. 2004
    ..The results presented may have clinical implications for (3)He ADC measurements in assessing lung diseases such as chronic-obstructive-pulmonary-disease...
  79. ncbi request reprint Ultrafast magnetic resonance imaging of the neonate in a magnetic resonance-compatible incubator with a built-in coil
    Elspeth H Whitby
    Section of Academic Radiology, University of Sheffield, Sheffield, United Kingdom
    Pediatrics 113:e150-2. 2004
    ..MR imaging usually involves moving neonates away from their controlled environment to the scanner...
  80. ncbi request reprint Postmortem MR imaging of the fetus: an adjunct or a replacement for conventional autopsy?
    Elspeth H Whitby
    Academic Unit of Radiology, University of Sheffield, MRI Department Floor C, Royal Hallamshire Hospital, UK
    Semin Fetal Neonatal Med 10:475-83. 2005
    ..It often provides more information in cases of central nervous system abnormalities, but is less accurate for cardiac abnormalities. Targeted, image-guided biopsy may allow histological diagnosis following postmortem MRI...
  81. ncbi request reprint Dynamic radial projection MRI of inhaled hyperpolarized 3He gas
    Jim M Wild
    Unit of Academic Radiology, University of Sheffield, UK
    Magn Reson Med 49:991-7. 2003
    ....
  82. doi request reprint Neonatal cochlear function: measurement after exposure to acoustic noise during in utero MR imaging
    Michael J Reeves
    Academic Unit of Radiology, University of Sheffield, Royal Hallamshire Hospital, Glossop Rd, C Floor, Sheffield S10 2JF, England
    Radiology 257:802-9. 2010
    ..To establish whether fetal exposure to the operating noise of 1.5-T magnetic resonance (MR) imaging is associated with cochlear injury and subsequent hearing loss in neonates...
  83. ncbi request reprint Effects of creatine supplementation on cerebral white matter in competitive sportsmen
    Iain D Wilkinson
    Academic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom
    Clin J Sport Med 16:63-7. 2006
    ..To determine the neurobiochemical sequelae of oral creatine monohydrate supplementation in active athletes...
  84. doi request reprint The clinical course after stereotactic radiosurgical amygdalohippocampectomy with neuroradiological correlates
    Nigel Hoggard
    Academic Unit of Radiology, University of Sheffield, Sheffield, England
    Neurosurgery 62:336-44; discussion 344-6. 2008
    ..In this study, we analyzed the magnetic resonance imaging (MRI) and spectroscopic changes that follow the treatment and report the clinical sequelae of the procedure...
  85. pmc Low field strength magnetic resonance imaging of the neonatal brain
    E H Whitby
    Department of Academic Radiology, Floor C, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Arch Dis Child Fetal Neonatal Ed 88:F203-8. 2003
    ..Ultrasound is the reference standard for neonatal imaging...
  86. ncbi request reprint SNR phase order k-space encoding (SPOKE)
    Martyn N J Paley
    Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    Magn Reson Imaging 25:1402-8. 2007
    ..Applications may also be found for 3D volumetric acquisitions where two dimensions can be SPOKE encoded...
  87. ncbi request reprint Simultaneous parallel inclined readout image technique
    Martyn N J Paley
    Section of Academic Radiology, Royal Hallamshire Hospital, University of Sheffield, S10 2JF Sheffield, UK
    Magn Reson Imaging 24:557-62. 2006
    ....
  88. ncbi request reprint Magnetic resonance spectroscopic abnormalities in sporadic and variant Creutzfeldt-Jakob disease
    H G Pandya
    Section of Academic Radiology, Royal Hallamshire Hospital, Floor C Glossop Road, Sheffield, UK
    Clin Radiol 58:148-53. 2003
    ..To study the proton MR spectroscopic findings in Creutzfeldt-Jakob disease (CJD) (sporadic and variant)...
  89. ncbi request reprint Proton MR spectroscopy of polymicrogyria and heterotopia
    Elysa Widjaja
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, England
    AJNR Am J Neuroradiol 24:2077-81. 2003
    ..The aim of this study was to determine the MR spectroscopic characteristics of polymicrogyria and heterotopia compared with those of normal frontal lobe white matter...
  90. ncbi request reprint Contrast-enhanced fluid-attenuated inversion recovery imaging for leptomeningeal disease in children
    Paul D Griffiths
    Unit of Academic Radiology, University of Sheffield, England
    AJNR Am J Neuroradiol 24:719-23. 2003
    ..To develop an MR imaging method that improves detection of leptomeningeal disease when compared with the current reference standard, contrast-enhanced T1-weighted imaging...
  91. ncbi request reprint Pediatric head and neck lesions: assessment of vascularity by MR digital subtraction angiography
    Weng Kong Chooi
    Section of Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, England
    AJNR Am J Neuroradiol 25:1251-5. 2004
    ..We investigated the use of dynamic MR digital subtraction angiography as a noninvasive adjunct for the assessment of the vascularity of these abnormalities...
  92. ncbi request reprint Postmortem MR imaging of the fetal and stillborn central nervous system
    Paul D Griffiths
    Section of Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    AJNR Am J Neuroradiol 24:22-7. 2003
    ..We evaluated the diagnostic accuracy of postmortem MR imaging of the fetal brain and spine when compared with the reference standard, autopsy...
  93. ncbi request reprint Assessment of blood supply to intracranial pathologies in children using MR digital subtraction angiography
    Weng Kong Chooi
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Pediatr Radiol 36:1057-62. 2006
    ..MR digital subtraction angiography (MR-DSA) is a contrast-enhanced MR angiographic sequence that enables time-resolved evaluation of the cerebral circulation...
  94. ncbi request reprint Interleaved pulsed MAMBA: a new parallel slice imaging method
    Martyn N J Paley
    Section of Academic Radiology, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    Magn Reson Med 48:1043-50. 2002
    ..Extension of interleaved coil design to two or three dimensions is feasible, which could provide full spatial coverage combined with ultra-rapid data acquisition...
  95. ncbi request reprint MR imaging and spectroscopy in Lhermitte-Duclos disease
    S Nagaraja
    Academic Unit of Radiology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
    Neuroradiology 46:355-8. 2004
    ....
  96. ncbi request reprint Design and initial evaluation of a low-cost 3-Tesla research system for combined optical and functional MR imaging with interventional capability
    M Paley
    Section of Academic Radiology and Department of Psychology, University of Sheffield, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, England
    J Magn Reson Imaging 13:87-92. 2001
    ..This novel, low-cost, high field system appears to be a useful research tool for functional and interventional studies of rat brain and allows concurrent optical spectroscopy. J. Magn. Reson. Imaging 2001;13:87-92...
  97. pmc How well do we investigate patients with suspected subarachnoid haemorrhage? The continuing need for cerebrospinal fluid investigations
    M L A Schofield
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, UK
    Postgrad Med J 80:27-30. 2004
    ..To demonstrate the extent of compliance with established guidelines for the investigation of suspected subarachnoid haemorrhage (SAH) and the implications of non-compliance...
  98. ncbi request reprint Choice of cross size in stereology--a cautionary note
    J M Dickson
    Department of Biomedical Science, Alfred Denny Building, University of Sheffield, Western Bank, Sheffield, S10 2TN, UK
    Neuroradiology 45:896-9. 2003
    ..Investigators should be aware of this fact, especially when trying to make direct comparisons between volume estimates derived from the stereological method using different cross sizes...
  99. ncbi request reprint Magnetic resonance spectroscopy changes following haemopoietic stem cell transplantation in children with cerebral adrenoleukodystrophy
    Daniel J Warren
    Radiology Department, Royal Hallamshire Hospital, and Academic Section of Radiology, University of Sheffield, UK
    Dev Med Child Neurol 49:135-9. 2007
    ....
  100. ncbi request reprint Cerebral perfusion abnormalities in children with Sturge-Weber syndrome shown by dynamic contrast bolus magnetic resonance perfusion imaging
    Amlyn L Evans
    Department of Radiology, Royal Hallamshire Hospital, Sheffield, United Kingdom
    Pediatrics 117:2119-25. 2006
    ..In this article, we assess the utility of magnetic resonance perfusion in demonstrating perfusion abnormalities in pediatric cases of Sturge-Weber syndrome...
  101. doi request reprint Imaging in acute ischaemic stroke: essential for modern stroke care
    Daniel J Warren
    Radiology Department, Royal Hallamshire Hospital, Sheffield NHS Teaching Hospitals Trust, Sheffield S10 2JF, UK
    Postgrad Med J 86:409-18. 2010
    ..This review highlights the basic imaging findings of acute stroke and discusses the role of advanced CT and MR techniques as well as options for vascular imaging...