Elizabeth Gray

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. doi Accumulation of cortical hyperphosphorylated neurofilaments as a marker of neurodegeneration in multiple sclerosis
    Elizabeth Gray
    MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, UK
    Mult Scler 19:153-61. 2013
  2. pmc The PPAR-γ agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
    Elizabeth Gray
    Multiple Sclerosis and Stem Cell Group, Burden Centre, Institute of Clinical Neurosciences, Frenchay Hospital, University of Bristol, Bristol BS16 1JB, UK
    J Neuroinflammation 9:63. 2012
  3. doi Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function
    Elizabeth Gray
    University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1JB, UK
    Eur J Neurosci 33:1421-32. 2011
  4. doi Neurofilament dot blot assays: novel means of assessing axon viability in culture
    Kelly Hares
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, Clinical Sciences, University of Bristol, North Bristol, UK
    J Neurosci Methods 198:195-203. 2011
  5. doi Changes in expression of the antioxidant enzyme SOD3 occur upon differentiation of human bone marrow-derived mesenchymal stem cells in vitro
    Helen Nightingale
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristo, Bristol, UK
    Stem Cells Dev 21:2026-35. 2012
  6. doi Elevated myeloperoxidase activity in white matter in multiple sclerosis
    Elizabeth Gray
    MS Laboratories, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1JB, United Kingdom
    Neurosci Lett 444:195-8. 2008
  7. doi Inflammatory cytokine induced regulation of superoxide dismutase 3 expression by human mesenchymal stem cells
    Kevin Kemp
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, Clinical Sciences North Bristol, University of Bristol, Bristol, UK
    Stem Cell Rev 6:548-59. 2010
  8. doi Elevated matrix metalloproteinase-9 and degradation of perineuronal nets in cerebrocortical multiple sclerosis plaques
    Elizabeth Gray
    MS Laboratories, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK
    J Neuropathol Exp Neurol 67:888-99. 2008
  9. doi Human mesenchymal stem cells increase anti-oxidant defences in cells derived from patients with Friedreich's ataxia
    Rimi Dey
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Bristol, UK
    Cerebellum 11:861-71. 2012
  10. doi Purkinje cell fusion and binucleate heterokaryon formation in multiple sclerosis cerebellum
    Kevin Kemp
    Multiple Sclerosis and Stem Cell, School of Clinical Sciences, University of Bristol, Bristol, BS16 1JB, UK
    Brain 135:2962-72. 2012

Collaborators

Detail Information

Publications11

  1. doi Accumulation of cortical hyperphosphorylated neurofilaments as a marker of neurodegeneration in multiple sclerosis
    Elizabeth Gray
    MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, UK
    Mult Scler 19:153-61. 2013
    ..Perikaryal accumulation of abnormally phosphorylated neurofilament proteins has been reported in some neurodegenerative diseases...
  2. pmc The PPAR-γ agonist pioglitazone protects cortical neurons from inflammatory mediators via improvement in peroxisomal function
    Elizabeth Gray
    Multiple Sclerosis and Stem Cell Group, Burden Centre, Institute of Clinical Neurosciences, Frenchay Hospital, University of Bristol, Bristol BS16 1JB, UK
    J Neuroinflammation 9:63. 2012
    ..Recent evidence has suggested that oligodendrocyte peroxisomes may play an important role in protecting neurons from inflammatory damage...
  3. doi Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function
    Elizabeth Gray
    University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1JB, UK
    Eur J Neurosci 33:1421-32. 2011
    ....
  4. doi Neurofilament dot blot assays: novel means of assessing axon viability in culture
    Kelly Hares
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, Clinical Sciences, University of Bristol, North Bristol, UK
    J Neurosci Methods 198:195-203. 2011
    ....
  5. doi Changes in expression of the antioxidant enzyme SOD3 occur upon differentiation of human bone marrow-derived mesenchymal stem cells in vitro
    Helen Nightingale
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristo, Bristol, UK
    Stem Cells Dev 21:2026-35. 2012
    ..This should help guide further in vivo work establishing the therapeutic and antioxidative potential of MSC and their differentiated progeny...
  6. doi Elevated myeloperoxidase activity in white matter in multiple sclerosis
    Elizabeth Gray
    MS Laboratories, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1JB, United Kingdom
    Neurosci Lett 444:195-8. 2008
    ..Demyelination in MS is associated with increased activity of MPO, suggesting that this production of reactive oxygen species may contribute to axonal injury within plaques...
  7. doi Inflammatory cytokine induced regulation of superoxide dismutase 3 expression by human mesenchymal stem cells
    Kevin Kemp
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, Clinical Sciences North Bristol, University of Bristol, Bristol, UK
    Stem Cell Rev 6:548-59. 2010
    ..SOD3 secretion by MSCs maybe of relevance to treatment strategies for inflammatory disease of the central nervous system...
  8. doi Elevated matrix metalloproteinase-9 and degradation of perineuronal nets in cerebrocortical multiple sclerosis plaques
    Elizabeth Gray
    MS Laboratories, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK
    J Neuropathol Exp Neurol 67:888-99. 2008
    ..Matrix metalloproteinase-mediated degradation of PNs in cortical plaques may, therefore, contribute to neuronal dysfunction and degeneration in MS patients...
  9. doi Human mesenchymal stem cells increase anti-oxidant defences in cells derived from patients with Friedreich's ataxia
    Rimi Dey
    Multiple Sclerosis and Stem Cell Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Bristol, UK
    Cerebellum 11:861-71. 2012
    ..This study further suggests the potential therapeutic use of MSCs in patients with FRDA...
  10. doi Purkinje cell fusion and binucleate heterokaryon formation in multiple sclerosis cerebellum
    Kevin Kemp
    Multiple Sclerosis and Stem Cell, School of Clinical Sciences, University of Bristol, Bristol, BS16 1JB, UK
    Brain 135:2962-72. 2012
    ..It also suggests an exciting new avenue for therapeutic intervention, as enhancement or manipulation of fusion events may have a therapeutic role in cellular protection in multiple sclerosis...
  11. ncbi Elevated activity and microglial expression of myeloperoxidase in demyelinated cerebral cortex in multiple sclerosis
    Elizabeth Gray
    Glial Cell Biology Laboratories, University of Bristol Institute of Clinical Neuroscience, Frenchay Hospital, Bristol, UK
    Brain Pathol 18:86-95. 2008
    ....