Robert L J Graham

Summary

Affiliation: University of Ulster
Country: UK

Publications

  1. pmc Microbial proteomics: a mass spectrometry primer for biologists
    Robert Lj Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, UK
    Microb Cell Fact 6:26. 2007
  2. ncbi request reprint Adenosine in the venoms from viperinae snakes of the genus Bitis: identification and quantitation using LC/MS and CE/MS
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Biochem Biophys Res Commun 333:88-94. 2005
  3. ncbi request reprint Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
    Toxicon 51:121-9. 2008
  4. pmc A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthropi
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry BT52 1SA, UK
    Genome Biol 8:R110. 2007
  5. ncbi request reprint Multidimensional analysis of the insoluble sub-proteome of Oceanobacillus iheyensis HTE831, an alkaliphilic and halotolerant deep-sea bacterium isolated from the Iheya ridge
    Robert L J Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, UK
    Proteomics 7:82-91. 2007
  6. ncbi request reprint Multidimensional proteomic analysis of the soluble subproteome of the emerging nosocomial pathogen Ochrobactrum anthropi
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, United Kingdom
    J Proteome Res 5:3145-53. 2006
  7. ncbi request reprint A combined shotgun and multidimensional proteomic analysis of the insoluble subproteome of the obligate thermophile, Geobacillus thermoleovorans T80
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry BT52 1SA, United Kingdom
    J Proteome Res 5:2465-73. 2006
  8. ncbi request reprint Top-down proteomic analysis of the soluble sub-proteome of the obligate thermophile, Geobacillus thermoleovorans T80: insights into its cellular processes
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, United Kingdom
    J Proteome Res 5:822-8. 2006
  9. ncbi request reprint Identification and functional analysis of a novel bradykinin inhibitory peptide in the venoms of New World Crotalinae pit vipers
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
    Biochem Biophys Res Commun 338:1587-92. 2005
  10. doi request reprint Quantitative proteomic analysis of the heat stress response in Clostridium difficile strain 630
    Shailesh Jain
    School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, Co Londonderry, North Ireland, United Kingdom
    J Proteome Res 10:3880-90. 2011

Collaborators

Detail Information

Publications13

  1. pmc Microbial proteomics: a mass spectrometry primer for biologists
    Robert Lj Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, UK
    Microb Cell Fact 6:26. 2007
    ..Finally in order to illustrate the power of microbial proteomics a case study of its current application within the Bacilliaceae is given together with a description of the emerging discipline of metaproteomics...
  2. ncbi request reprint Adenosine in the venoms from viperinae snakes of the genus Bitis: identification and quantitation using LC/MS and CE/MS
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, UK
    Biochem Biophys Res Commun 333:88-94. 2005
    ..Adenosine may thus act at the site of envenomation causing local vasodilatation and may play a role in the subsequent systemic hypotension observed...
  3. ncbi request reprint Elucidation of trends within venom components from the snake families Elapidae and Viperidae using gel filtration chromatography
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
    Toxicon 51:121-9. 2008
    ....
  4. pmc A semi-quantitative GeLC-MS analysis of temporal proteome expression in the emerging nosocomial pathogen Ochrobactrum anthropi
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry BT52 1SA, UK
    Genome Biol 8:R110. 2007
    ..We used proteomics to investigate how protein expression of this organism changes with time during growth...
  5. ncbi request reprint Multidimensional analysis of the insoluble sub-proteome of Oceanobacillus iheyensis HTE831, an alkaliphilic and halotolerant deep-sea bacterium isolated from the Iheya ridge
    Robert L J Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, UK
    Proteomics 7:82-91. 2007
    ..iheyensis HTE831...
  6. ncbi request reprint Multidimensional proteomic analysis of the soluble subproteome of the emerging nosocomial pathogen Ochrobactrum anthropi
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, United Kingdom
    J Proteome Res 5:3145-53. 2006
    ..In addition, a number of potential virulence factors of relevance to both plant and human disease were identified...
  7. ncbi request reprint A combined shotgun and multidimensional proteomic analysis of the insoluble subproteome of the obligate thermophile, Geobacillus thermoleovorans T80
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry BT52 1SA, United Kingdom
    J Proteome Res 5:2465-73. 2006
    ..In addition, a number of proteins were identified that are known to be involved in the transport of compatible solutes, known to be important in microbial stress responses...
  8. ncbi request reprint Top-down proteomic analysis of the soluble sub-proteome of the obligate thermophile, Geobacillus thermoleovorans T80: insights into its cellular processes
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine, County Londonderry, BT52 1SA, United Kingdom
    J Proteome Res 5:822-8. 2006
    ..In addition, it has enabled us to assign a degree of functionality to 29 out of 36 gene products detected in this study that were hitherto described as being only hypothetical conserved proteins...
  9. ncbi request reprint Identification and functional analysis of a novel bradykinin inhibitory peptide in the venoms of New World Crotalinae pit vipers
    Robert Leslie James Graham
    School of Biomedical Sciences, University of Ulster, Coleraine BT52 1SA, UK
    Biochem Biophys Res Commun 338:1587-92. 2005
    ..BIP thus represents a novel biological entity from snake venom...
  10. doi request reprint Quantitative proteomic analysis of the heat stress response in Clostridium difficile strain 630
    Shailesh Jain
    School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, Co Londonderry, North Ireland, United Kingdom
    J Proteome Res 10:3880-90. 2011
    ..Thus we have a benchmark proteome for this pathogen, leading to a deeper understanding of its physiology and metabolism informed by the unique functional and adaptive processes used during a temperature upshift mimicking host pyrexia...
  11. doi request reprint Proteomic analysis of the insoluble subproteome of Clostridium difficile strain 630
    Shailesh Jain
    University of Ulster, Coleraine, Co Londonderry, Northern Ireland
    FEMS Microbiol Lett 312:151-9. 2010
    ..difficile 630. This would be a significant initial step towards a full systems understanding of this clinically important microorganism...
  12. doi request reprint Semiquantitative Analysis of Clinical Heat Stress in Clostridium difficile Strain 630 Using a GeLC/MS Workflow with emPAI Quantitatio
    Nigel G Ternan
    Northern Ireland Centre for Food and Health NICHE, School of Biomedical Sciences, University of Ulster, Coleraine, Co Londonderry, Northern Ireland, United Kingdom
    PLoS ONE 9:e88960. 2014
    ..The current work has thus allowed development of a heat stress model for the key cellular processes of protein folding and export. ..
  13. ncbi request reprint A role for carbon catabolite repression in the metabolism of phosphonoacetate by Agromyces fucosus Vs2
    Sheryl Naomi O'Loughlin
    School of Biomedical Sciences, University of Ulster, Coleraine, UK
    FEMS Microbiol Lett 261:133-40. 2006
    ..Excision of stained zymogram gel pieces, followed by tryptic digestion and mass spectrometric analysis, allowed the identification of phosphonoacetate hydrolase-derived peptides...