- Actin-induced hyperactivation of the Ras signaling pathway leads to apoptosis in Saccharomyces cerevisiaeC W Gourlay
Department of Molecular Biology and Biotechnology, University of Sheffield, Firth Court, Western Bank, Sheffield S10 2TN, United Kingdom
Mol Cell Biol 26:6487-501. 2006..This pathway represents the first defined link between environmental sensing, actin remodeling, and apoptosis in Saccharomyces cerevisiae...
- A role for actin in aging and apoptosisC W Gourlay
Department of Molecular Biology and Biotechnology, Firth Court, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
Biochem Soc Trans 33:1260-4. 2005..Conversely, increased actin dynamics correlates with low ROS levels and increased survival. Our current studies have focused on identifying pathways which couple changes in actin dynamics to cell death...