Affiliation: University of Bristol
- Antisense suppression of tau in cultured rat oligodendrocytes inhibits process formationDavid Gordon
Department of Biochemistry and Molecular Biology, The University of Queensland, Brisbane, Queensland, Australia
J Neurosci Res 86:2591-601. 2008..The timing of oligonucleotide addition to oligodendrocyte cultures was important, with addition of antisense at the time of plating into culture having the most significant effect on morphology through reduction of tau expression...
- Enhanced green fluorescent protein-expressing human mesenchymal stem cells retain neural marker expressionDavid Gordon
MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, BS16 1JB, UK
J Neuroimmunol 193:59-67. 2008..We show that human MSCs expressing EGFP represent an attractive and practical source of stem cells for the study of repair and regeneration in neurological models...
- Human mesenchymal stem cells infiltrate the spinal cord, reduce demyelination, and localize to white matter lesions in experimental autoimmune encephalomyelitisDavid Gordon
MS Labs, Burden Centre, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, United Kingdom
J Neuropathol Exp Neurol 69:1087-95. 2010..These data support a potential role for hMSCs in autologous cell therapy in multiple sclerosis...
- Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltrationDavid Gordon
MS Stem Cell Group, Burden Neurological Institute, University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol BS16 1LE, UK
Neurosci Lett 448:71-3. 2008..Our findings therefore help confirm the therapeutic potential of mesenchymal stem cells, show that this does indeed extend to human cells, and are consistent with a peripheral or systemic immune effect of human MSCs in this model...
- Human mesenchymal stem cell culture for neural transplantationDavid Gordon
University of Bristol Institute of Clinical Neurosciences, Frenchay Hospital, Bristol, UK
Methods Mol Biol 549:103-18. 2009....
- Child rights and child poverty: can the international framework of children's rights be used to improve child survival rates?Simon Pemberton
University of Bristol, Bristol, United Kingdom
PLoS Med 4:1567-70. 2007
- Poverty, child undernutrition and morbidity: new evidence from IndiaShailen Nandy
School for Policy Studies, University of Bristol, Bristol, England
Bull World Health Organ 83:210-6. 2005....
- Neo-colonialism versus sound globalization policy in medical educationHans Karle
World Federation for Medical Education, University of Copenhagen, Faculty of Health Sciences, Blegdamsvej 3b, DK-2200 Copenhagen N, Denmark
Med Educ 42:956-8. 2008
- Nuclear targeting of the growth hormone receptor results in dysregulation of cell proliferation and tumorigenesisBecky L Conway Campbell
Institute for Molecular Bioscience and School of Biomedical Sciences, University of Queensland, Brisbane 4072, Australia
Proc Natl Acad Sci U S A 104:13331-6. 2007..We conclude that aberrant nuclear localization of GHR is a marker of high proliferative status and is sufficient to induce tumorigenesis and tumor progression...
- Transfusion of apoptotic beta-cells induces immune tolerance to beta-cell antigens and prevents type 1 diabetes in NOD miceChang Qing Xia
Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610, USA
Diabetes 56:2116-23. 2007..The transfusion of apoptotic beta-cells effectively protects against type 1 diabetes in NOD mice by inducing immune tolerance to beta-cell antigens. This approach has great potential for immune intervention for human type 1 diabetes...
- First vaginal delivery at an older age: Does it carry an extra risk for the development of stress urinary incontinence?Asnat Groutz
Urogynecology and Pelvic Floor Unit, Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Neurourol Urodyn 26:779-82. 2007..First delivery at an older age is not an uncommon event in modern obstetric practice. The present study was undertaken to compare the prevalence of postpartum stress urinary incontinence (SUI) according to maternal age and mode of delivery...
- High prevalence of false chordae tendinae in patients without left ventricular tachycardiaSarah K Gualano
Department of Medicine, Division of Cardiology, University of Michigan, Ann Arbor, Michigan, USA
Pacing Clin Electrophysiol 30:S156-9. 2007..However, it is unknown whether pretest bias contributes to an apparent association with disease. The purpose of this study was to determine the prevalence of false chords on direct inspection of the LV endocardium...
- Role of socioeconomic markers and state prohibition policy in predicting alcohol consumption among men and women in India: a multilevel statistical analysisS V Subramanian
Harvard School of Public Health, Kresge Building, 7th Floor Rm 716, 677 Huntington Avenue, Boston, MA, USA
Bull World Health Organ 83:829-36. 2005..To investigate the independent contribution of individual socioeconomic markers and state prohibition policy on alcohol consumption among men and women in India...
- Characterization of agonist-induced motilin receptor trafficking and its implications for tachyphylaxisVahideh Lamian
Clinical Discovery Technologies, Bristol-Myers Squibb Medical Imaging, 331 Treble Cove Rd, North Billerica, MA 01862, USA
Mol Pharmacol 69:109-18. 2006....
- Interstitial cystitis and endometriosis in patients with chronic pelvic pain: The "Evil Twins" syndromeMaurice K Chung
Midwest Regional Center for Chronic Pelvic Pain and Bladder Control, The Medical Park of Lima Memorial Hospital, Lima, OH 45805, USA
JSLS 9:25-9. 2005..To determine the prevalence of interstitial cystitis and endometriosis in patients with chronic pelvic pain...
- Brain natriuretic peptide predicts serious cardiac allograft rejection independent of hemodynamic measurementsAudrey H Wu
Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
J Heart Lung Transplant 24:52-7. 2005..91. CONCLUSIONS: BNP predicts new episodes of serious cardiac allograft rejection, particularly vascular rejection, independent of hemodynamic measurements, and may be a useful part of rejection surveillance...
- Cesarean section: does it really prevent the development of postpartum stress urinary incontinence? A prospective study of 363 women one year after their first deliveryAsnat Groutz
Urogynecology and Pelvic Floor Unit, Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Israel
Neurourol Urodyn 23:2-6. 2004..We undertook a prospective study to compare the prevalence of SUI among primiparae 1 year after spontaneous vaginal delivery versus elective cesarean section, or cesarean section performed for obstructed labor...
- Health policy in relation to improving equity in child healthDavid Gordon
Townsend Centre for International Poverty Research, University of Bristol, Bristol, United Kingdom
Pediatrics 112:725-6. 2003..The United States spent 3700 dollars per person on health care in 1997. In the United Kingdom, we spent less than one third of that...
- The new bisphosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronateAllan Lipton
Milton S Hershey Medical Center, P O Box 850 H 46, Hershey, PA 17003, USA
Cancer Invest 20:45-54. 2002..In conclusion, Zol is the first bisphosphonate to demonstrate efficacy in both lytic and blastic disease. The unique properties of this novel agent should be further explored in future clinical trials...