Affiliation: University College London
- Factor XI deficiencyK Gomez
Haemophilia Centre and Thrombosis Unit, Royal Free Hospital, Hampstead, London, UK
Haemophilia 14:1183-9. 2008..The publication of the crystal structure has greatly enhanced our understanding of the structure-function relationship in FXI. The impact of recent studies on our understanding of the role of FXI in coagulation is discussed...
- An interactive mutation database for human coagulation factor IX provides novel insights into the phenotypes and genetics of hemophilia BP M Rallapalli
Division of Biosciences, Research Department of Structural and Molecular Biology, University College London, London, UK
J Thromb Haemost 11:1329-40. 2013..Factor IX (FIX) is important in the coagulation cascade, being activated to FIXa on cleavage. Defects in the human F9 gene frequently lead to hemophilia B...
- The role of recombinant factor VIIa for obstetric block in women with severe factor XI deficiencyS Setty
Department of Anaesthesia, The Royal Free Hospital, London, UK
Haemophilia 17:906-9. 2011..Low-dose rFVIIa seems to be effective and safe in the management of delivery and enables provision of regional blocks in women with severe FXI deficiency...