C A Goddard

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Genistein activates CFTR-mediated Cl(-) secretion in the murine trachea and colon
    C A Goddard
    Department of Physiology, University of Cambridge, United Kingdom
    Am J Physiol Cell Physiol 279:C383-92. 2000
  2. ncbi A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo
    J W Wiseman
    1Department of Physiology, University of Cambridge, Cambridge, UK
    Gene Ther 10:1654-62. 2003
  3. ncbi Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart
    M J Killeen
    Physiological Laboratory, University of Cambridge, Cambridge, UK
    Acta Physiol (Oxf) 189:33-46. 2007
  4. ncbi Optimisation of real-time quantitative RT-PCR for the evaluation of non-viral mediated gene transfer to the airways
    A C Rose
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Gene Ther 9:1312-20. 2002

Collaborators

Detail Information

Publications4

  1. ncbi Genistein activates CFTR-mediated Cl(-) secretion in the murine trachea and colon
    C A Goddard
    Department of Physiology, University of Cambridge, United Kingdom
    Am J Physiol Cell Physiol 279:C383-92. 2000
    ..We conclude that genistein activates CFTR-mediated Cl(-) secretion in the murine trachea and distal colon...
  2. ncbi A comparison of linear and branched polyethylenimine (PEI) with DCChol/DOPE liposomes for gene delivery to epithelial cells in vitro and in vivo
    J W Wiseman
    1Department of Physiology, University of Cambridge, Cambridge, UK
    Gene Ther 10:1654-62. 2003
    ..To establish that PEI can be used to deliver a physiologically relevent gene in vivo, we used it to restore Cl(-) secretion by CFTR gene delivery in the airways of a CF mouse model...
  3. ncbi Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart
    M J Killeen
    Physiological Laboratory, University of Cambridge, Cambridge, UK
    Acta Physiol (Oxf) 189:33-46. 2007
    ..Hypokalaemia is associated with a lethal form of ventricular tachycardia (VT), torsade de pointes, through pathophysiological mechanisms requiring clarification...
  4. ncbi Optimisation of real-time quantitative RT-PCR for the evaluation of non-viral mediated gene transfer to the airways
    A C Rose
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Gene Ther 9:1312-20. 2002
    ..Although it remains to be seen if CF patients can tolerate long-term expression of wild-type CFTR, these data demonstrate that TaqMan RT-PCR is an effective tool to accurately quantify transgene expression in the airways...