Eva Gluenz

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 64:1529-39. 2007
  2. pmc The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    Mol Cell Biol 31:1012-21. 2011
  3. doi request reprint An expanded family of proteins with BPI/LBP/PLUNC-like domains in trypanosome parasites: an association with pathogenicity?
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Biochem Soc Trans 39:966-70. 2011
  4. pmc Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 69:666-80. 2008
  5. pmc Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis
    Richard J Wheeler
    The Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    BMC Biol 10:1. 2012
  6. pmc The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles
    Bill Wickstead
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 5:e15020. 2010
  7. pmc Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    FASEB J 24:3117-21. 2010
  8. pmc The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology
    Richard J Wheeler
    The Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 79:647-62. 2011
  9. doi request reprint Bioinformatic insights to the ESAG5 and GRESAG5 gene families in kinetoplastid parasites
    Amy R Barker
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Biochem Parasitol 162:112-22. 2008
  10. doi request reprint Ultrastructural investigation methods for Trypanosoma brucei
    Johanna L Höög
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX13RE, United Kingdom
    Methods Cell Biol 96:175-96. 2010

Detail Information

Publications13

  1. pmc Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 64:1529-39. 2007
    ..We also describe a hitherto unrecognized, intramitochondrial, filamentous structure rich in basic proteins that links the kDNA discs during their segregation and is maintained between them for an extended period of the cell cycle...
  2. pmc The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, United Kingdom
    Mol Cell Biol 31:1012-21. 2011
    ..This new view of the complexities of kinetoplast duplication emphasizes the dependencies between the dynamic remodelling of the cytoskeleton and the inheritance of the mitochondrial genome...
  3. doi request reprint An expanded family of proteins with BPI/LBP/PLUNC-like domains in trypanosome parasites: an association with pathogenicity?
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Biochem Soc Trans 39:966-70. 2011
    ..Current work focuses on the elucidation of possible roles for this gene family in infection. This is likely to provide novel insights into the evolution of the BPI/LBP/PLUNC-like domains...
  4. pmc Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 69:666-80. 2008
    ..In contrast, cytokinesis was incomplete in bloodstream forms, where cleavage was initiated but cells failed to progress to abscission. Kinetoplast duplication was uninterrupted resulting in cells with multiple kinetoplasts and flagella...
  5. pmc Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis
    Richard J Wheeler
    The Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK
    BMC Biol 10:1. 2012
    ..This presents a technical challenge. Accurate identification and quantitation of the DNA content of these organelles is a central requirement of any automated analysis method...
  6. pmc The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles
    Bill Wickstead
    Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 5:e15020. 2010
    ....
  7. pmc Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    FASEB J 24:3117-21. 2010
    ..We propose that the main function of the amastigote flagellum is to act as a sensory organelle with important functions in host-parasite interactions and signaling in the intracellular stage of the L. mexicana life cycle...
  8. pmc The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology
    Richard J Wheeler
    The Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Microbiol 79:647-62. 2011
    ..This data set therefore provides a platform which will be of use for post-genomic analyses of Leishmania cell biology in relation to differentiation and infection...
  9. doi request reprint Bioinformatic insights to the ESAG5 and GRESAG5 gene families in kinetoplastid parasites
    Amy R Barker
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Mol Biochem Parasitol 162:112-22. 2008
    ..Together, these results provide insights into the structure and evolution of an important extended gene family, and present a number of testable hypotheses which will aid in elucidating the function of ESAG5...
  10. doi request reprint Ultrastructural investigation methods for Trypanosoma brucei
    Johanna L Höög
    Sir William Dunn School of Pathology, University of Oxford, Oxford OX13RE, United Kingdom
    Methods Cell Biol 96:175-96. 2010
    ..We also introduce a novel high-pressure freezing protocol, which followed by rapid freeze substitution and HM20 embedding generates T. brucei samples displaying good cell morphology, which are suitable for immunocytochemistry...
  11. doi request reprint Flagellum assembly and function during the Leishmania life cycle
    Eva Gluenz
    Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK
    Curr Opin Microbiol 13:473-9. 2010
    ....
  12. ncbi request reprint Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes
    Reuben Sharma
    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK
    Protist 159:137-51. 2008
    ..Thus, the asymmetric cell division cycle provides a mechanism for a change in cell morphology and also an explanation for how a reduction in cell length can occur in a cell shaped by a stable microtubule array...
  13. pmc The Trypanosoma cruzi metacyclic-specific protein Met-III associates with the nucleolus and contains independent amino and carboxyl terminal targeting elements
    Eva Gluenz
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    Int J Parasitol 37:617-25. 2007
    ..To investigate the function of Met-III, we used gene deletion. This showed that Met-III is not required for the development of metacyclic trypomastigotes and that null mutants can complete the life-cycle in vitro...