Research Topics
| Paul GlasziouSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Ethics and evidence-based medicineMalcolm H Parker
Med J Aust 176:138-9; author reply 139. 2002
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. The Standards for Reporting of Diagnostic Accuracy GroupPatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Croat Med J 44:635-8. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalizability of its results...
The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration. The Standards for Reporting of Diagnostic Accuracy GroupPatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Croat Med J 44:639-50. 2003..Complete and informative reporting can only lead to better decisions in health care...
Do all fractures need full immobilisation?Paul Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 335:612-3. 2007
Can we rely on the best trial? A comparison of individual trials and systematic reviewsPaul P Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, UK
BMC Med Res Methodol 10:23. 2010..However, for many clinical questions a systematic review will not be available, or may not be up to date. One option could be to use the evidence from an individual trial to answer the question?..
Diagnostic accuracy of nitroglycerine as a 'test of treatment' for cardiac chest pain: a systematic reviewKatherine Grailey
Department of Public Health and Primary Care, University of Oxford, Old Road Campus, Old Road, Oxford OX3 7LF, UK
Emerg Med J 29:173-6. 2012..However, further studies are needed to determine the diagnostic accuracy of nitroglycerine for recurrent exertional chest pain...
Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2)Matthias Briel
Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada
Trials 10:49. 2009..The aim of STOPIT-2 is to determine the magnitude and determinants of possible bias introduced by stopping RCTs early for benefit...
An implementation research agendaMartin P Eccles
Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK
Implement Sci 4:18. 2009..This editorial presents the summary of the CERAG report and recommendations...
When are randomised trials unnecessary? Picking signal from noisePaul Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 334:349-51. 2007..This model may help to reduce controversy about evidence for treatments whose effects are so dramatic that randomised trials are unnecessary...
When should a new test become the current reference standard?Paul Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford, United Kingdom
Ann Intern Med 149:816-22. 2008..Second, resolving these disagreements requires a fair, but not necessarily perfect, umpire test. Finally, umpire tests include consequences, such as prognosis and response to treatment, as well as causal exposures and other test results...
Monitoring cholesterol levels: measurement error or true change?Paul P Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford, United Kingdom
Ann Intern Med 148:656-61. 2008..Cholesterol level monitoring is a common clinical activity, but the optimal monitoring interval is unknown and practice varies...
Assessing the quality of researchPaul Glasziou
Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 328:39-41. 2004
Promoting evidence-based non-drug interventions: time for a non-pharmacopoeia?Paul P Glasziou
Med J Aust 191:52-3. 2009
Which health-related quality of life score? A comparison of alternative utility measures in patients with Type 2 diabetes in the ADVANCE trialPaul Glasziou
Centre for Evidence Based Practice, Institute of Health Sciences, Oxford University, Oxford, UK
Health Qual Life Outcomes 5:21. 2007..The study aimed to measure the impact of diabetes on various health-related quality of life domains, and compare several summary utility measures...
Monitoring in chronic disease: a rational approachPaul Glasziou
University of Oxford, Department of Primary Health Care, Oxford OX3 7LF, UK
BMJ 330:644-8. 2005
Managing the evidence floodPaul Glasziou
Centre for Evidence Based Practice, Department of Primary Health Care, University of Oxford, Old Road Campus, Oxford OX3 7LF, England, UK
Surg Clin North Am 86:193-9, xi. 2006..Unless we focus some of our research and practice effort on better organizing, filtering, and using the research that we have, the gap between what we know and what we do will continue to grow...
What is missing from descriptions of treatment in trials and reviews?Paul Glasziou
Centre for Evidence Based Medicine, Department of Primary Health Care, University of Oxford, Oxford OX3 7LF
BMJ 336:1472-4. 2008
What are the basic self-monitoring components for cardiovascular risk management?Alison M Ward
Department of Primary Health Care, The University of Oxford, Headington, UK
BMC Med Res Methodol 10:105. 2010..We examined the interventions included in systematic reviews of self-monitoring for four clinical problems that increase cardiovascular disease risk...
Individual patient meta-analysis of self-monitoring of an oral anticoagulation protocolRafael Perera
Department of Primary Health Care, University of Oxford, UK
J Heart Valve Dis 17:233-8. 2008..In order to overcome these limitations and allow further investigation of the data, the study aim is to undertake an Individual Patient Data (IPD) meta-analysis...
A model for reflection for good clinical practiceJohn I Balla
Centre for Evidence Based Medicine, Department of Primary Care, Old Road Campus, Headington Oxford OX3 7LF, UK
J Eval Clin Pract 15:964-9. 2009..In line with good practice, the model also links the crucial knowledge used in decision making, to value judgments made in relation to the patient...
Use of evidence in hypertension guidelines: should we measure in both arms?Emily Parker
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, UK
Br J Gen Pract 59:e87-92. 2009..It is suggested that if guidelines better justified recommendations and cited primary literature to support claims, a greater percentage of practitioners might accept and adhere to such guidance...
Assessing differential attrition in clinical trials: self-monitoring of oral anticoagulation and type II diabetesCarl Heneghan
Department of Primary Health Care, University of Oxford, Oxford, UK
BMC Med Res Methodol 7:18. 2007..Analyzing drop out rates and when they occur may give important information about the patient characteristics and trial characteristics that affect the overall uptake of an intervention...
Using the Turning Research Into Practice (TRIP) database: how do clinicians really search?Emma Meats
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Headington, Oxford, United Kingdom
J Med Libr Assoc 95:156-63. 2007..This study aimed to examine clinicians' current search behavior when using the Turning Research Into Practice (TRIP) database to examine search engine use and the ways it might be improved...
Identification and guided treatment of ventricular dysfunction in general practice using blood B-type natriuretic peptideDavid Mant
University Department of Primary Health Care, University of Oxford, Old Road Campus, Oxford
Br J Gen Pract 58:393-9. 2008..B-type natriuretic peptide (BNP) is a blood test which detects ventricular wall stretch and is being increasingly used in primary care on limited evidence...
Hypertension guideline recommendations in general practice: awareness, agreement, adoption, and adherenceCarl Heneghan
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford
Br J Gen Pract 57:948-52. 2007..GPs vary greatly in their clinical management of hypertension, for reasons that are poorly understood...
Patterns of 'leakage' in the utilisation of clinical guidelines: a systematic reviewSharon Mickan
Department of Primary Health Care, International Program in Evidence Based Health Care, University of Oxford, Oxford, UK
Postgrad Med J 87:670-9. 2011..Research evidence is insufficient to change physicians' behaviour. In 1996, Pathman developed a four step model: that physicians need to be aware of, agree with, adopt, and adhere to guidelines...
No surgical innovation without evaluation: the IDEAL recommendationsPeter McCulloch
Nuffield Department of Surgery, University of Oxford, Oxford, UK
Lancet 374:1105-12. 2009..Achievement of improved design, conduct, and reporting of surgical research will need concerted action by editors, funders of health care and research, regulatory bodies, and professional societies...
A simple method to correct for the design effect in systematic reviews of trials using paired dichotomous dataRafael Perera
Department of Primary Health Care, University of Oxford, Rosemary Rue Building, Headington, OX3 7LF, Oxford, UK
J Clin Epidemiol 60:975-8. 2007..An incorrect analysis (without adjustment) would usually overestimate the precision of the estimate. We discuss a simple method of adjustment that deals with this problem...
Was the study big enough? Two "café" rulesPaul Glasziou
Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
ACP J Club 147:A8-9. 2007
Corticosteroids for pain relief in sore throat: systematic review and meta-analysisGail Hayward
Department of Primary Health Care, University of Oxford, Bond University, Gold Coast, Queensland 4229, Australia
BMJ 339:b2976. 2009..To evaluate whether systemic corticosteroids improve symptoms of sore throat in adults and children...
Evidence-based medicine teaching in UK medical schoolsEmma Meats
Department of Primary Health Care, University of Oxford, Oxford, UK
Med Teach 31:332-7. 2009..It is recognized that clinicians need training in evidence-based medicine (EBM), however there is considerable variation in the content and methods of the EBM curriculum in UK medical schools...
How quickly should we titrate antihypertensive medication? Systematic review modelling blood pressure response from trial dataDaniel S Lasserson
Department of Primary Health Care, University of Oxford, Old Road Campus, Headington, Oxford OX3 7LF, UK
Heart 97:1771-5. 2011..There are no evidence syntheses available to guide clinicians on when to titrate antihypertensive medication after initiation...
A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndromeNourieh Hoveyda
Department of Primary Health Care, Centre for Evidence Based Medicine, University of Oxford, Rosemary Rue Building, Old Road Campus, Headington, Oxford, UK
BMC Gastroenterol 9:15. 2009..We searched Ovid versions of MEDLINE (1950-2007), EMBASE (1980-2007), CINAHL (1982-2007), AMED (1985-2007), the Cochrane library and hand searched retrieved papers...
Epley and the slow boat from research to practicePaul Glasziou
Centre for Evidence-based Medicine, Department of Primary Health Care, University of Oxford, Oxford, UK
Evid Based Med 13:34-5. 2008
Cochrane systematic review of colorectal cancer screening using the fecal occult blood test (hemoccult): an updatePaul Hewitson
Department of Primary Health Care, University of Oxford, Oxford, United Kingdom
Am J Gastroenterol 103:1541-9. 2008....
The paths from research to improved health outcomesPaul Glasziou
University of Oxford, Oxford, UK
Evid Based Nurs 8:36-8. 2005
The rise of cholesterol testing: how much is unnecessaryHelen Doll
Department of Primary Health Care, University of Oxford, Old Road Campus, Headington, Oxford, UK
Br J Gen Pract 61:e81-8. 2011..Laboratory testing has increased dramatically over recent decades, which is a consequence particularly of repeat testing or monitoring, as either a response to treatment or follow-up...
The EBM journal selection process: how to find the 1 in 400 valid and highly relevant new research articlesPaul Glasziou
Oxford University, Oxford, UK
Evid Based Med 11:101. 2006
Was the study big enough? Two café rulesPaul Glasziou
Centre for Evidence Based Medicine, University of Oxford, Oxford, UK
Evid Based Med 11:69-70. 2006
What is EBM and how should we teach it?Paul Glasziou
Centre for Evidence Based Medicine, University of Oxford, Old Road Campus, Old Road, Headington, Oxford OX3 7LF, UK
Med Teach 28:303-4. 2006
The state of primary-care researchDavid Mant
Department of Primary Health Care, Oxford University, Oxford, UK
Lancet 364:1004-6. 2004
Practice corner: the first symptom of hyperkalemia is deathPaul Glasziou
Centre for Evidence-based Medicine, Oxford, England, UK
ACP J Club 140:A13. 2004
What makes evidence-based journal clubs succeed?Robert S Phillips
Centre for Evidence Based Medicine, Oxford, England, UK
ACP J Club 140:A11-2. 2004
Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?Paul P Glasziou
c Professor John Simes, NHMRC Clinical Trials Centre, Locked Bag 77, Camperdown, NSW 1450, Australia
Med J Aust 177:428-34. 2002..To measure the cost-effectiveness of cholesterol-lowering therapy with pravastatin in patients with established ischaemic heart disease and average baseline cholesterol levels...
The Cochrane Library: access for all AustraliansPaul P Glasziou
Med J Aust 177:532-3. 2002
Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD InitiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, The Netherlands
Radiology 226:24-8. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
Towards complete and accurate reporting of studies of diagnostic accuracy: The STARD InitiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Ann Intern Med 138:40-4. 2003..If medical journals adopt the checklist and the flow diagram, the quality of reporting of studies of diagnostic accuracy should improve to the advantage of the clinicians, researchers, reviewers, journals, and the public...
The STARD statement for reporting studies of diagnostic accuracy: explanation and elaborationPatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, 1100 DE Amsterdam, The Netherlands
Clin Chem 49:7-18. 2003..Complete and informative reporting can only lead to better decisions in healthcare...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, Netherlands
BMJ 326:41-4. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in a study, and to evaluate a study's generalisability...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic AccuracyPatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, 1100 DE Amsterdam, The Netherlands
Clin Chem 49:1-6. 2003..To comprehend the results of diagnostic accuracy studies, readers must understand the design, conduct, analysis, and results of such studies. That goal can be achieved only through complete transparency from authors...
General practice research: attitudes and involvement of Queensland general practitionersDeborah A Askew
Centre for General Practice, School of Population Health, The University of Queensland Medical School, Herston Road, Herston, QLD 4006, Australia
Med J Aust 177:74-7. 2002..To determine general practitioners' (GPs') attitudes towards and involvement in general practice research...
Benefits, harms and costs of screening mammography in women 70 years and over: a systematic reviewAlexandra L Barratt
Department of Public Health and Community Medicine, University of Sydney, NSW
Med J Aust 176:266-71. 2002..To assess the (i) benefits, (ii) harms and (iii) costs of continuing mammographic screening for women 70 years and over...
Natural remedies for osteoporosis in postmenopausal womenB Del Mar Christopher
Centre for General Practice, Medical School, University of Queensland, Herston
Med J Aust 176:182-3. 2002
The STARD statement for reporting studies of diagnostic accuracy: explanation and elaborationPatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Ann Intern Med 138:W1-12. 2003..Complete and informative reporting can only lead to better decisions in health care...
Toward complete and accurate reporting of studies of diagnostic accuracy. The STARD initiativePatrick M Bossuyt
Dept of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Am J Clin Pathol 119:18-22. 2003..If medical journals adopt the checklist and the flow diagram, the quality of reporting of studies of diagnostic accuracy should improve, to the advantage of clinicians, researchers, reviewers, journals, and the public...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
Clin Biochem 36:2-7. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
Do individualized medication effectiveness tests (n-of-1 trials) change clinical decisions about which drugs to use for osteoarthritis and chronic pain?C Jane Nikles
Discipline of General Practice, The University of Queensland, Herston, Queensland, Australia
Am J Ther 12:92-7. 2005..Our results provide a new (individual) perspective on the well-known recommendation for paracetamol as first-line treatment for chronic pain and demonstrate that it is feasible to provide IMETs nationally by mail and telephone...
Resting injured limbs delays recovery: a systematic reviewCharlotte E Nash
Centre for General Practice, University of Queensland, Herston, Queensland, Australia
J Fam Pract 53:706-12. 2004..CONCLUSIONS: We should not assume any benefit for immobilization after acute upper or lower limb injuries in adults. Rest appears to be overused as a treatment. More trials are needed to identify optimal programs for early mobilization...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Fam Pract 21:4-10. 2004..Our aim was to improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalizability of its results...
Prolotherapy injections, saline injections, and exercises for chronic low-back pain: a randomized trialMichael J Yelland
Centre for General Practice and School of Population Health, University of Queensland, Brisbane, Australia
Spine (Phila Pa 1976) 29:9-16; discussion 16. 2004..To assess the efficacy of a prolotherapy injection and exercise protocol in the treatment of chronic nonspecific low back pain...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology, Amsterdam, The Netherlands
Ann Clin Biochem 40:357-63. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy in order to allow readers to assess the potential for bias in a study and to evaluate the generalizability of its results...
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center-University of Amsterdam, P. O. Box 22700, 1100 DE Amsterdam, The Netherlands
AJR Am J Roentgenol 181:51-5. 2003..If medical journals adopt the checklist and the flow diagram, the quality of reporting of studies of diagnostic accuracy should improve to the advantage of clinicians, researchers, reviewers, journals, and the public...
Toward complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Acad Radiol 10:664-9. 2003....
Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiativePatrick M Bossuyt
Academic Medical Center, Department of Clinical Epidemiology, University of Amsterdam, Amsterdam, The Netherlands
Clin Chem Lab Med 41:68-73. 2003..To improve the accuracy and completeness of reporting of studies of diagnostic accuracy, to allow readers to assess the potential for bias in the study and to evaluate its generalisability...
Computerised reminders and feedback in medication management: a systematic review of randomised controlled trialsJohn W Bennett
University Health Service, University of Queensland, Gordon Greenwood Building, Brisbane, Queensland 4072, Australia
Med J Aust 178:217-22. 2003..To systematically review randomised controlled trials (RCTs) of computer-generated medication reminders or feedback directed to healthcare providers or patients...
Information overload: what's behind it, what's beyond it?Paul P Glasziou
Med J Aust 189:84-5. 2008
