Research Topics
| F J GilbertSummaryAffiliation: University of Aberdeen Country: UK Publications
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Detail Information
Publications
Variable size computer-aided detection prompts and mammography film reader decisionsFiona J Gilbert
Division of Applied Medicine, School of Medicine and Dentistry, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, UK
Breast Cancer Res 10:R72. 2008....
Participants' preference for type of leaflet used to feed back the results of a randomised trial: a surveyStephen Brealey
Department of Health Sciences, Seebohm Rowntree Building, University of York, Heslington, York YO10 5DD, UK
Trials 11:116. 2010..This study aims to determine participants' preferences for type of leaflet (short versus long) used to summarise the findings of a randomised trial; and to test whether certain characteristics explained participants' preferences...
Visually assessed breast density, breast cancer risk and the importance of the craniocaudal viewStephen W Duffy
Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Breast Cancer Res 10:R64. 2008..A particularly strong association with risk has been observed when density is measured using interactive threshold software. This, however, is a labour-intensive process for large-scale studies...
Improving response rates using a monetary incentive for patient completion of questionnaires: an observational studyStephen D Brealey
Department of Health Sciences, York Trials Unit, Seebohm Rowntree Building, University of York, Heslington, York YO10 5DD, UK
BMC Med Res Methodol 7:12. 2007..To improve response rates in our trial in primary care we tested the effect of introducing an unconditional direct payment of 5 pounds for the completion of postal questionnaires...
Is computer aided detection (CAD) cost effective in screening mammography? A model based on the CADET II studyCarla Guerriero
Health Service Research and Policy Department, London School of Hygiene and Tropical Medicine, London, UK
BMC Health Serv Res 11:11. 2011..The aim of this study is to investigate whether the use of a single reader with CAD is more cost-effective than double reading...
The DAMASK trial protocol: a pragmatic randomised trial to evaluate whether GPs should have direct access to MRI for patients with suspected internal derangement of the kneeStephen D Brealey
Department of Health Sciences, York Trials Unit, Seebohm Rowntree Building, University of York, Heslington, York YO10 5DD, UK
BMC Health Serv Res 6:133. 2006..The objective of this study was to resolve uncertainty whether GPs should refer patients with suspected internal derangement of the knee for MRI or to an orthopaedic specialist in secondary care...
APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profilingRussell D Petty
University of Aberdeen, UK
BMC Cancer 9:434. 2009..The aim was to identify novel 5FU resistance mechanisms and qualify these as candidate biomarkers and therapeutic targets...
Cancers in BRCA1 and BRCA2 carriers and in women at high risk for breast cancer: MR imaging and mammographic featuresFiona J Gilbert
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Lilian Sutton Bldg, Foresterhill, Aberdeen, AB25 2ZD, Scotland
Radiology 252:358-68. 2009....
Should we use MRI to screen women at high-risk of breast cancer?F J Gilbert
Department of Radiology, University of Aberdeen, Aberdeen, Scotland, UK
Cancer Imaging 5:32-8. 2005..The Dutch and Canadian studies have reported the sensitivity of MRI to be 71% and 77% compared to mammography which was 40% and 36%, respectively, in asymptomatic high risk cohorts...
Breast cancer screening in high risk womenFiona J Gilbert
Radiology Department, University of Aberdeen, Aberdeen, UK
Cancer Imaging 8:S6-9. 2008..National recommendations have been produced by the National Institute of Clinical Excellence in the UK and also by the American Cancer Society...
Single reading with computer-aided detection for screening mammographyFiona J Gilbert
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom
N Engl J Med 359:1675-84. 2008..We conducted a trial to determine whether the performance of a single reader using a computer-aided detection system would match the performance achieved by two readers...
Single reading with computer-aided detection and double reading of screening mammograms in the United Kingdom National Breast Screening ProgramFiona J Gilbert
Department of Radiology, University of Aberdeen, Lilian Sutton Bldg, Foresterhill, Aberdeen, Scotland
Radiology 241:47-53. 2006..To retrospectively determine if the use of a computer-aided detection (CAD) system can improve the performance of single reading of screening mammograms to match that of double reading in the United Kingdom...
Low back pain: influence of early MR imaging or CT on treatment and outcome--multicenter randomized trialFiona J Gilbert
Department of Radiology, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland
Radiology 231:343-51. 2004..To establish whether early use of magnetic resonance (MR) imaging or computed tomography (CT) influences treatment and outcome of patients with low back pain (LBP) and whether it is cost-effective...
Research misconductF J Gilbert
Department of Radiology, University of Aberdeen, Aberdeen, UK
Clin Radiol 58:499-504. 2003..The issue of how the radiology community might tackle research misconduct is discussed with reference to guidance from the Medical Research Council, the Wellcome Trust and the Committee of Publication Ethics...
Positron emission tomography using [(18)F]-fluorodeoxy-D-glucose to predict the pathologic response of breast cancer to primary chemotherapyI C Smith
John Mallard Scottish Positron Emission Tomography Center, Scotland, United Kingdom
J Clin Oncol 18:1676-88. 2000..To determine whether [(18)F]-fluorodeoxy-D-glucose ([(18)F]-FDG) positron emission tomography (PET) can predict the pathologic response of primary and metastatic breast cancer to chemotherapy...
Accuracy of T1 measurement in dynamic contrast-enhanced breast MRI using two- and three-dimensional variable flip angle fast low-angle shotJ A Brookes
Department of Bio Medical Physics and Bio Engineering, University of Aberdeen, Foresterhill, United Kingdom
J Magn Reson Imaging 9:163-71. 1999..Rigorous quality assurance programs with calibrated phantoms are thus recommended, to verify the accuracy with which T1 measurements are obtained...
The biological correlates of macroscopic breast tumour structure measured using fractal analysis in patients undergoing neoadjuvant chemotherapyP Di Giovanni
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK
Breast Cancer Res Treat 133:1199-206. 2012....
Use of a capillary input function with cardiac output for the estimation of lesion pharmacokinetic parameters: preliminary results on a breast cancer patientP Di Giovanni
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, UK
Phys Med Biol 56:1743-53. 2011..The technique may also have applicability to T1-weighted DCE-MRI data...
The accuracy of pharmacokinetic parameter measurement in DCE-MRI of the breast at 3 TP Di Giovanni
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK
Phys Med Biol 55:121-32. 2010..These results demonstrate the importance of high temporal resolution, accurate T1 measurement and good B1 homogeneity...
Low-bandwidth tele-ultrasoundJ A Brebner
Department of General Practice and Primary Care, University of Aberdeen, UK
J Telemed Telecare 5:S75-6. 1999..Observers were not satisfied with low-bandwidth transmission of ultrasound images despite adequate diagnostic accuracy. Dynamic ultrasound images transmitted at 384 kbit/s were viewed as both diagnostically acceptable and accurate...
What is achieved by mammographic surveillance after breast conservation treatment for breast cancer?F Ashkanani
Department of Surgery, University of Aberdeen, Aberdeen, UK
Am J Surg 182:207-10. 2001..This study has investigated this aspect and, in particular, whether mammography or clinical examination or both allowed an early detection of recurrence of the disease in the conserved breast...
Economic analysis of outreach assessment clinics in breast screening programmesM M Van Der Pol
Health Economics Research Unit, University of Aberdeen, Foresterhill, Scotland
Int J Health Plann Manage 14:57-67. 1999....
Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administrationS I K Semple
Department of Radiology, University of Aberdeen, Scotland, UK
Ann Oncol 17:1393-8. 2006..Reduction in (18)F-FDG PET metabolism has previously been shown to correlate with histological response to primary chemotherapy...
The impact of operative approach for oesophageal cancer on outcome: the transhiatal approach may influence circumferential margin involvementS A Suttie
Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, United Kingdom
Eur J Surg Oncol 38:157-65. 2012..This study aims to determine the impact of operative approach on tumour margin involvement and survival...
Does early imaging influence management and improve outcome in patients with low back pain? A pragmatic randomised controlled trialF J Gilbert
Department of Radiology, University of Aberdeen, UK
Health Technol Assess 8:iii, 1-131. 2004..To establish whether the early use of sophisticated imaging techniques influences the clinical management and outcome of patients with low back pain (LBP) and whether it is cost-effective...
Screening for breast cancer in women at moderate and high riskF J Gilbert
Department of Radiology, University of Aberdeen, Aberdeen, Scotland, UK
Clin Oncol (R Coll Radiol) 17:240-3. 2005
Age threshold for endoscopy and risk of missing upper gastrointestinal malignancy--data from the Scottish audit of gastric and oesophageal cancerP S Phull
Gastrointestinal and Liver Service, Aberdeen Royal Infirmary, Aberdeen, UK
Aliment Pharmacol Ther 23:229-33. 2006..Urgent endoscopy is indicated for suspected upper gastrointestinal malignancy. However, there is limited evidence on the age threshold for performing urgent endoscopy in uncomplicated dyspepsia (that is, without alarm features)...
Magnetic resonance imaging in gynecological oncologyVanessa N Harry
Department of Gynaecological Oncology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
Int J Gynecol Cancer 19:186-93. 2009..This paper reviews the current role of MRI in gynecological cancers and highlights the potential of novel techniques in improving patient care...
Predicting the response of advanced cervical and ovarian tumors to therapyVanessa N Harry
Department of Gynaecological Oncology, Aberdeen Royal Infirmary, Aberdeen, UK
Obstet Gynecol Surv 64:548-60. 2009....
The intrinsic shape of the human lumbar spine in the supine, standing and sitting postures: characterization using an active shape modelJudith R Meakin
Bone and Musculoskeletal Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen, UK
J Anat 215:206-11. 2009..Systematic differences in the behaviour of the spine, when changing posture, were found that suggest that the shape of the spine may affect its biomechanics...
Opportunities for PET to deliver clinical benefit in cancer: breast cancer as a paradigmIan N Fleming
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK
Cancer Imaging 10:144-52. 2010..The aim of this paper is to consider how the availability of new tracers, or new applications for existing PET/CT technologies, could deliver clinical benefit in cancer, using breast cancer as a paradigm...
Increasing participant recruitment into large-scale screening trials: experience from the CADET II studyMaureen G C Gillan
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Lilian Sutton Building, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
J Med Screen 16:180-5. 2009..We report on recruitment strategies implemented in a randomized evaluation of computer-aided detection in women attending routine screening in the UK Breast Screening Programme...
B1 transmission-field inhomogeneity and enhancement ratio errors in dynamic contrast-enhanced MRI (DCE-MRI) of the breast at 3TChe A Azlan
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, UK
J Magn Reson Imaging 31:234-9. 2010....
Characterizing the shape of the lumbar spine using an active shape model: reliability and precision of the methodJudith R Meakin
Department of Radiology, University of Aberdeen, Foresterhill, Aberdeen, UK
Spine (Phila Pa 1976) 33:807-13. 2008..Analysis of positional magnetic resonance images of normal volunteers...
Correlation of MRI/PET rim enhancement in breast cancer: a delivery related phenomenon with therapy implications?Scott I K Semple
Department of Radiology, University of Aberdeen, Foresterhill, Scotland, UK
Lancet Oncol 4:759. 2003
Neoadjuvant chemotherapy in breast cancer: significantly enhanced response with docetaxelIan C Smith
Department of Academic Radiology, University of Aberdeen, Foresterhill, Aberdeen, Scotland, United Kingdom
J Clin Oncol 20:1456-66. 2002..To compare the efficacy of neoadjuvant (NA) docetaxel (DOC) with anthracycline-based therapy and determine the efficacy of NA DOC in patients with breast cancer initially failing to respond to anthracycline-based NA chemotherapy (CT)...
The relationship between vascular and metabolic characteristics of primary breast tumoursScott I K Semple
Department of Radiology, University of Aberdeen, Lilian Sutton Building, AB252ZD Aberdeen, Scotland, UK
Eur Radiol 14:2038-45. 2004..MRI and PET provide methods of assessing breast tumour vascularity and metabolism in vivo using the exchange rate constants of dynamic MRI, and DUR of PET, respectively, these measures being related but not equivalent...
The effect of axial load on the sagittal plane curvature of the upright human spine in vivoJudith R Meakin
Bone and Musculoskeletal Programme, Division of Applied Medicine, Room 2 26 IMS Building, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
J Biomech 41:2850-4. 2008..The variation in behaviour of differently shaped spines may have further implications for the effects of load in lifting manoeuvres and in understanding the aetiology of back pain...
Mammographic features of breast cancers at single reading with computer-aided detection and at double reading in a large multicenter prospective trial of computer-aided detection: CADET IIJonathan J James
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland
Radiology 256:379-86. 2010..To evaluate the mammographic features of breast cancer that favor lesion detection with single reading and computer-aided detection (CAD) or with double reading...
Reporting and management of breast lesions detected using MRIB J G Dall
Department of Radiology, Leeds General Infirmary, Leeds, UK
Clin Radiol 66:1120-8. 2011..The format of MRI reporting is discussed in detail as is the usefulness of discussion of cases at multidisciplinary meetings. Illustrative cases are used to clarify the points made...
The clinical effectiveness and cost-effectiveness of different surveillance mammography regimens after the treatment for primary breast cancer: systematic reviews registry database analyses and economic evaluationC Robertson
Health Services Research Unit, University of Aberdeen, Aberdeen, UK
Health Technol Assess 15:v-vi, 1-322. 2011..Surveillance mammography is used to detect these cancers, but the optimal frequency of surveillance and the length of follow-up are unclear...
Influence of imaging on clinical decision making in the treatment of lower back painM G Gillan
Department of Radiology, University of Aberdeen, Foresterhill, AB25 2ZD, Scotland, UK
Radiology 220:393-9. 2001..To assess the impact of cross-sectional imaging with magnetic resonance (MR) imaging or computed tomography (CT) on clinical decision making for patients with lower back pain (LBP)...
The measurement of fetal liver T(*)(2) in utero before and after maternal oxygen breathing: progress towards a non-invasive measurement of fetal oxygenation and placental functionS I Semple
Department of Bio medical Physics, University of Aberdeen, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, AB25 2ZD Scotland
Magn Reson Imaging 19:921-8. 2001..This technique may potentially be applied to the identification and understanding of placental dysfunction in intra-uterine growth retardation...
Evaluation of a prospective scoring system designed for a multicenter breast MR imaging screening studyRuth M L Warren
Department of Radiology, Addenbrooke's Hospital, Cambridge, England, and Department of Radiology, University of Aberdeen, Aberdeen, Scotland
Radiology 239:677-85. 2006..In the context of screening, quantitative enhancement parameters appear to be less useful for lesion characterization...
A test of performance of breast MRI interpretation in a multicentre screening studyRuth Warren
Department of Radiology, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK
Magn Reson Imaging 24:917-29. 2006..Scoring systems developed on one equipment software may not be transferable to other manufacturers...
The diagnostic acceptability of low-bandwidth transmission for tele-ultrasoundJ A Brebner
Department of General Practice and Primary Care, University of Aberdeen, UK
J Telemed Telecare 6:335-8. 2000..62) and 78% (kappa = 0.63). The quality of dynamic ultrasound images transmitted at 384 kbit/s was diagnostically acceptable, but was unsatisfactory at 128 kbit/s...
Dynamic contrast enhanced MRI of the axilla in women with breast cancer: comparison with pathology of excised nodesA D Murray
Department of Radiology, University of Aberdeen and Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
Br J Radiol 75:220-8. 2002....
A comparison of digital and screen-film mammography using quality control phantomsP E Undrill
Department of Biomedical Physics and Bioengineering, University of Aberdeen, Foresterhill, Aberdeen, Scotland
Clin Radiol 55:782-90. 2000..To compare the performance of a direct digital mammography system with normal-view and magnified-view conventional screen-film methods using quality control phantoms...
A pilot study with long term follow up of hyperbaric oxygen pretreatment in patients with locally advanced breast cancer undergoing neo-adjuvant chemotherapyS D Heys
Department of Surgery, University of Aberdeen, Scotland
Undersea Hyperb Med 33:33-43. 2006..Five year survival in those who tolerated the trial regime was 73% and did not differ between the groups. This mortality was cancer related...
Monitoring primary breast cancer throughout chemotherapy using FDG-PETGarry M McDermott
School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Breast Cancer Res Treat 102:75-84. 2007..The purpose was to determine whether there is an optimal method for defining tumour volume and an optimal imaging time for predicting pathologic chemotherapy response...
Axial BMD, change in BMD and bone turnover do not predict breast cancer incidence in early postmenopausal womenA Stewart
Osteoporosis Research Unit, Department of Medicine and Therapeutics, University of Aberdeen, Victoria Pavilion, Woolmanhill Hospital, Aberdeen, AB25 1LD, UK
Osteoporos Int 16:1627-32. 2005..In conclusion, in perimenopausal or early postmenopausal women there is no relationship between the incidence of breast cancer and BMD, change in BMD or bone turnover...
Effects of mailed dissemination of the Royal College of Radiologists' guidelines on general practitioner referrals for radiography: a time series analysisL Matowe
Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, UK
Clin Radiol 57:575-8. 2002..To evaluate the effect of postal dissemination of the third edition of the Royal College of Radiologists' (RCR) guidelines on general practitioner referrals for radiography...
Endoscopic palliative treatment for esophageal and gastric cancer: techniques, complications, and survival in a population-based cohort of 948 patientsA M Thompson
Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, DD1 9SY, Dundee, Scotland, United Kingdom
Surg Endosc 18:1257-62. 2004....
Morbidity and mortality rates following gastric cancer surgery and contiguous organ removal, a population based studyS Nanthakumaran
Department of Upper Gastrointestinal Surgery, Aberdeen Royal Infirmary, Ward 33, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
Eur J Surg Oncol 31:1141-4. 2005..05). CONCLUSIONS: The risk of more extensive resection is not balanced by improved survival in this population based series. Extending gastric resection to involve contiguous organs should be confined to highly selected cases...
Reading protocol for dynamic contrast-enhanced MR images of the breast: sensitivity and specificity analysisRuth M L Warren
Department of Radiology, Addenbrooke's Hospital, Cambridge, England
Radiology 236:779-88. 2005..Interreader correlation was moderately good, and evidence of learning was seen. Equipment manufacturer, field strength, and age affected specificity but not sensitivity...
BRCA1 mutation and young age predict fast breast cancer growth in the Dutch, United Kingdom, and Canadian magnetic resonance imaging screening trialsMadeleine M A Tilanus-Linthorst
Department of Surgery, Erasmus University Medical Centre, Rotterdam, The Netherlands
Clin Cancer Res 13:7357-62. 2007..We investigated the effect of a BRCA1 or BRCA2 mutation and age on the growth rate of breast cancers, as this may influence the optimal screening frequency...
