Affiliation: University of Bristol
Gibson W, Peacock L. Fluorescent proteins reveal what trypanosomes get up to inside the tsetse fly. Parasit Vectors. 2019;12:6 pubmed publisher
..Without fluorescent proteins we would still be in the "dark ages" of understanding what trypanosomes get up to inside the tsetse fly. ..
Gibson W. Molecular characterization of field isolates of human pathogenic trypanosomes. Trop Med Int Health. 2001;6:401-6 pubmed
..However, virulence or fly transmissibility have been correlated with molecular markers in some instances. ..
Gibson W, Stevens J, Mwendia C, Ngotho J, Ndung u J. Unravelling the phylogenetic relationships of African trypanosomes of suids. Parasitology. 2001;122:625-31 pubmed
..congolense Tsavo on database. In phylogenetic analysis of the SSU rRNA genes of Salivarian trypanosomes, T. congolense Tsavo grouped with T. simiae rather than T. congolense, suggesting that the name T. simiae Tsavo is more appropriate. ..
Gibson W. Liaisons dangereuses: sexual recombination among pathogenic trypanosomes. Res Microbiol. 2015;166:459-66 pubmed publisher
..The process involves meiosis and production of haploid gametes, and thus appears to be true sexual reproduction. This review looks at the experimental evidence concerning genetic exchange and identifies current gaps in our knowledge. ..
Hutchinson R, Gibson W. Rediscovery of Trypanosoma (Pycnomonas) suis, a tsetse-transmitted trypanosome closely related to T. brucei. Infect Genet Evol. 2015;36:381-388 pubmed publisher
..suis from other, better-known African tsetse-transmitted trypanosomes. The rediscovery of T. suis opens new lines of research into the evolution and biology of the African trypanosomes. ..
Gibson W, Backhouse T, Griffiths A. The human serum resistance associated gene is ubiquitous and conserved in Trypanosoma brucei rhodesiense throughout East Africa. Infect Genet Evol. 2002;1:207-14 pubmed
..These results are consistent with the hypothesis that new T.b. rhodesiense strains arise by genetic exchange among T. brucei ssp. spreading the SRA gene and thereby the trait for human serum resistance and human infectivity...
Gibson W. The SRA gene: the key to understanding the nature of Trypanosoma brucei rhodesiense. Parasitology. 2005;131:143-50 pubmed
Gibson W, Peacock L, Hutchinson R. Microarchitecture of the tsetse fly proboscis. Parasit Vectors. 2017;10:430 pubmed publisher
..We highlight the remarkable architecture of the tsetse proboscis, in particular the intricate structure of the distal end of the hypopharynx. Further work is needed to elucidate the function of this intriguing structure. ..