Research Topics
| Adam GibsonSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonateA P Gibson
Department of Medical Physics and Bioengineering, University College London, Malet Place Engineering Building, London WC1E 6BT, UK
Neuroimage 30:521-8. 2006..8 mm. These results suggest that optical tomography may provide an appropriate technique for non-invasive cot-side imaging of brain function...- Linear and nonlinear reconstruction for optical tomography of phantoms with nonscattering regionsAdam P Gibson
Department of Medical Physics and Bioengineering, University College London, London WC1E 6JA, United Kingdom
Appl Opt 44:3925-36. 2005..This study supports the use of linear reconstruction for dynamic imaging but suggests that, in all cases, image quality is likely to improve if the clear regions are modeled correctly... 
Diffuse optical imagingAdam Gibson
Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK
Philos Trans A Math Phys Eng Sci 367:3055-72. 2009..We aim to review the state of the art of optical imaging...- Optical tomography of a realistic neonatal head phantomAdam Gibson
Department of Medical Physics and Bioengineering, University College London, 11 20 Capper Street, London WC1E 6JA
Appl Opt 42:3109-16. 2003..The head-shaped mesh performed slightly better than the spherical mesh, particularly when the absorption of the central region of the phantom was increased... - Imaging changes in blood volume and oxygenation in the newborn infant brain using three-dimensional optical tomographyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, 11-20 Capper Street, London WC1E 6JA, UK
Phys Med Biol 49:1117-30. 2004..The results exhibit large changes in absorption coefficient at both wavelengths. Images corresponding to differences in concentrations of oxy- and deoxyhaemoglobin are in qualitative agreement with known physiological data... - Optical tomography of the breast using a multi-channel time-resolved imagerTara Yates
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 50:2503-17. 2005..Drawbacks of our current methodology and plans for overcoming them are discussed... - Assessment of an in situ temporal calibration method for time-resolved optical tomographyJeremy C Hebden
University College London, Department of Medical Physics and Bioengineering, 11 20 Capper Street, London WC1E 6JA, UK
J Biomed Opt 8:87-92. 2003..The effectiveness of the method is briefly demonstrated by imaging a solid object with tissue-equivalent optical properties... - Monitoring recovery after laser surgery of the breast with optical tomography: a case studyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, United Kingdom
Appl Opt 44:1898-904. 2005..Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed... - Three-dimensional optical topography of brain activity in infants watching videos of human movementTeresa Correia
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 57:1135-46. 2012..These results suggest that infants a few months old have regions which are specialized for reacting to human activity, and that these subtle changes can be effectively analysed using 3D optical topography... - Selection of regularization parameter for optical topographyTeresa Correia
University College London, Department of Medical Physics and Bioengineering, Gower Street, London WC1E 6BT, United Kingdom
J Biomed Opt 14:034044. 2009..We test them on two trial problems, deblurring and optical topography, and conclude that the L-curve method is the method of choice, though in particularly ill-posed problems, generalized cross-validation may provide an alternative... - Three-dimensional optical tomography of the premature infant brainJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, 11-20 Capper Street, London WC1E 6JA, UK
Phys Med Biol 47:4155-66. 2002.... - Identification of the optimal wavelengths for optical topography: a photon measurement density function analysisTeresa Correia
University College London, Department of Medical Physics and Bioengineering, Gower Street, London, WC1E 6BT United Kingdom
J Biomed Opt 15:056002. 2010..However, for the adult human head, the differences between interrogated volumes at NIR wavelengths are very small and image reconstruction is only slightly improved when measurements with overlapping sensitivities are used... - An elastically compressible phantom material with mechanical and x-ray attenuation properties equivalent to breast tissueB D Price
Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK
Phys Med Biol 55:1177-88. 2010..Varying the PVAL concentration from 7.5 to 20% w/v produces gels with Young's moduli from 20 to 220 kPa at 15% strain. These values are characteristic of normal and cancerous breast tissue, respectively... - Investigation of depth dependent changes in cerebral haemodynamics during face perception in infantsA Blasi
Biomedical Optics Research Lab, Department of Medical Physics and Bioengineering, Malet Place Engineering Building, University College London, London WC1E 6BT, UK
Phys Med Biol 52:6849-64. 2007..Activation maps were obtained using 3D reconstruction methods on multi source-detector separation optical topography data... - Assessing the validity of modulation transfer function evaluation techniques with application to small area and scanned digital detectorsB D Price
Department of Medical Physics and Bioengineering, University College London, London, United Kingdom
Rev Sci Instrum 79:113103. 2008..It was also found that use of such a step and shoot technique does cause a very small overall degradation in resolution. The resolution of overall images was calculated to be 0.1 lp/mm lower than that of the individual images acquired... - Transient haemodynamic events in neurologically compromised infants: a simultaneous EEG and diffuse optical imaging studyR J Cooper
Biomedical Optics Research Laboratory, Department of Medical Physics and Bioengineering, University College London, London, UK
Neuroimage 55:1610-6. 2011..The importance and physiological implications of our findings are discussed, as is the suitability of a combined EEG and diffuse optical imaging approach to the study and monitoring of neonatal brain injury... - Design and evaluation of a probe for simultaneous EEG and near-infrared imaging of cortical activationR J Cooper
Department of Medical Physics and Bioengineering, University College London, London WC1E 6BT, UK
Phys Med Biol 54:2093-102. 2009..We successfully acquired NIR optical and EEG data simultaneously for both our phantom and our human motor cortex experiments, clearly demonstrating the effectiveness and suitability of our 'opto-electrode'... - A method for generating patient-specific finite element meshes for head modellingA P Gibson
Department of Medical Physics and Bioengineering, University College London, UK
Phys Med Biol 48:481-95. 2003..However, data generated from a mesh of the best fit sphere were significantly different from data generated from the original neonatal head surface... - Three dimensional optical imaging of blood volume and oxygenation in the neonatal brainT Austin
Department of Paediatrics and Child Health, University College London, UK
Neuroimage 31:1426-33. 2006..These results suggest that optical tomography may provide an appropriate technique for investigating regional cerebral haemodynamics and oxygenation at the cotside... - Electrical impedance tomography of human brain function using reconstruction algorithms based on the finite element methodAndrew P Bagshaw
Department of Clinical Neurophysiology, University College London, UK
Neuroimage 20:752-64. 2003.... - Three-dimensional time-resolved optical mammography of the uncompressed breastLouise C Enfield
Department of Medical Physics and Bioengineering, University College London, London, WC1E 6BT, UK
Appl Opt 46:3628-38. 2007..Only half of the fibroadenomas scanned could be observed, but of those that could be detected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation... - A soft deformable tissue-equivalent phantom for diffuse optical tomographyJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 51:5581-90. 2006..The deformable phantoms may be used to test and calibrate optical tomography systems designed for use on patients with irregular or variable geometries... - Computational calibration method for optical tomographyTanja Tarvainen
Department of Applied Physics, University of Kuopio, P O Box 1627, FIN 70211 Kuopio, Finland
Appl Opt 44:1879-88. 2005..The results show that the coupling coefficients of the sources and detectors can be estimated with good accuracy. Furthermore, the results show that the method can significantly improve the quality of reconstructed images... - Time-resolved optical mammography using a liquid coupled interfaceTara D Yates
University College London, Department of Medical Physics and Bioengineering, London WC1E 6BT, United Kingdom
J Biomed Opt 10:054011. 2005..Preliminary images of a healthy human subject are also presented, which reveal subtle heterogeneity, particularly in the distribution of scatter. The ability to detect an absorbing target adjacent to the breast is also demonstrated... - An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systemsJeremy C Hebden
Department of Medical Physics and Bioengineering, University College London, Gower Street, London WC1E 6BT, UK
Phys Med Biol 53:329-37. 2008..Images of the phantom have been reconstructed using data acquired with a continuous wave optical topography system...