Research Topics
| A J GermanSummaryAffiliation: University of Bristol Country: UK Publications
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Detail Information
Publications
Eosinophilic diseases in two Cavalier King Charles spanielsA J German
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU
J Small Anim Pract 43:533-8. 2002..This report is the first to describe the concurrence of eosinophilic stomatitis and systemic eosinophilic disease in Cavalier King Charles spaniels, and suggest that this breed may be predisposed to eosinophilic syndromes...
Expression of major histocompatibility complex class II antigens in the canine intestineA J German
Department of Clinical Veterinary Science, University of Bristol, Langford, UK
Vet Immunol Immunopathol 61:171-80. 1998..Definition of constitutive expression of MHC class II within the canine intestine may be important in identifying upregulation of this molecule in inflammatory bowel diseases...
Measurement of IgG, IgM and IgA concentrations in canine serum, saliva, tears and bileA J German
University of Clinical Veterinary Science, University of Bristol, Langford, UK
Vet Immunol Immunopathol 64:107-21. 1998..Both findings should be taken into account in future studies of canine mucosal immunoglobulins...
Relative deficiency in IgA production by duodenal explants from German shepherd dogs with small intestinal diseaseA J German
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol, BS40 5DU, UK
Vet Immunol Immunopathol 76:25-43. 2000..It remains to be determined whether such a deficiency is a breed-related primary defect, or whether it arises secondary to the pathological processes within the intestinal mucosa...
Immune cell populations within the duodenal mucosa of dogs with enteropathiesA J German
Department of Clinical Veterinary Science, University of Bristol, UK
J Vet Intern Med 15:14-25. 2001..The altered mucosal immune cell populations observed in dogs with ARD or IBD may reflect an underlying immunologic pathogenesis in these disorders...
Chronic intestinal inflammation and intestinal disease in dogsA J German
Department of Clinical Veterinary Science, University of Bristol, Bristol, UK
J Vet Intern Med 17:8-20. 2003..This review includes discussion of the factors involved in breakdown of mucosal tolerance, the immunologic basis of canine enteropathies, and the use of novel immunotherapies for these diseases...
Fecal alpha1-proteinase inhibitor concentration in dogs receiving long-term nonsteroidal anti-inflammatory drug therapyK F Murphy
Department of Clinical Veterinary Science, University of Bristol, Bristol, UK
Vet Clin Pathol 32:136-9. 2003..The value of fecal alpha(1)-PI measurement in detecting unrelated gastrointestinal disease may be limited in dogs on NSAID therapy, but alpha(1)-PI may be a useful marker for NSAID-induced gastrointestinal damage...
Fecal alpha1-proteinase inhibitor concentration in dogs with chronic gastrointestinal diseaseK F Murphy
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU, UK
Vet Clin Pathol 32:67-72. 2003..Fecal alpha(1)-proteinase inhibitor (alpha(1)-PI) clearance is a reliable, noninvasive marker for protein-losing enteropathy in human beings. An assay for use in dogs has been developed and validated...
Sterile nodular panniculitis and pansteatitis in three weimaranersA J German
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU
J Small Anim Pract 44:449-55. 2003..This report thus describes a presumed sterile and idiopathic panniculitis/pansteatitis complex in weimaraner dogs. Although the aetiology is unknown, this may represent an immune-mediated disorder...
Effect of intestinal inflammation on fecal elastase concentration in dogsI A Battersby
School of Veterinary Medicine, University of Bristol, UK
Vet Clin Pathol 34:49-51. 2005..A commercially available ELISA kit for fecal elastase measurement can be used in the diagnosis of exocrine pancreatic insufficiency (EPI) in dogs. However, other causes of diarrhea also may affect fecal elastase concentration...
Comparison of direct and indirect tests for small intestinal bacterial overgrowth and antibiotic-responsive diarrhea in dogsA J German
Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol, UK
J Vet Intern Med 17:33-43. 2003..These results question the utility of quantitative duodenal juice bacteriology and indirect biochemical marker tests for SIBO in the investigation of canine gastrointestinal disorders...
Analysis of canine and feline haemograms using the VetScan HMT analyserE C Dewhurst
Langford Veterinary Diagnostics, Department of Clinical Veterinary Science, University of Bristol, Langford
J Small Anim Pract 44:443-8. 2003..For feline samples, although there was excellent correlation for Hct, Hb and RBC, the WBC and three-part white blood cell differential and platelet count should be interpreted with caution as they can be unreliable...
Unusual vascular ring anomaly associated with a persistent right aortic arch in two dogsA K House
Queen Mother Hospital, Royal Veterinary College, Hatfield
J Small Anim Pract 46:585-90. 2005..Surgical ligation and division of the left ligamentum arteriosum in both dogs, along with division of the left subclavian artery in the great Dane, resulted in resolution of clinical signs in both of the dogs in this report...
Adipokine gene expression in dog adipose tissues and dog white adipocytes differentiated in primary cultureI Eisele
Neuroendocrine and Obesity Biology Unit, Liverpool Centre for Nutritional Genomics, School of Clinical Sciences, University of Liverpool, University Clinical Departments, Liverpool L69 3GA, United Kingdom
Horm Metab Res 37:474-81. 2005..Investigation of adipokine production and function will provide insight into the mechanisms involved in obesity-related pathologies in dogs and serve as a model for the related human diseases...
Multicentric lymphoma in a dog after cyclosporine therapyL Blackwood
Small Animal Hospital, Department of Veterinary Clinical Science, University of Liverpool, Crown Street, Liverpool L7 7EX
J Small Anim Pract 45:259-62. 2004..As the use of cyclosporine in small animals is increasing, further work is required to substantiate and quantify the proposed increased risk...
Detection of endoparasites with zoonotic potential in dogs with gastrointestinal disease in the UKD J Batchelor
Department of Veterinary Clinical Science, Small Animal Teaching Hospital, University of Liverpool, Leahurst, Neston, Wirral, UK
Transbound Emerg Dis 55:99-104. 2008..Moreover, they provide information to direct future work in determining the risk to the human population from parasitic zoonoses of dogs...
