D Gems

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Nematode ageing: Putting metabolic theories to the test
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, London, NW1 2HE, UK
    Curr Biol 9:R614-6. 1999
  2. pmc Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    D Gems
    The Galton Laboratory, Department of Biology, University College London, England
    Genetics 154:1597-610. 2000
  3. ncbi request reprint Insulin/IGF signalling and ageing: seeing the bigger picture
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, NW1 2HE, London, UK
    Curr Opin Genet Dev 11:287-92. 2001
  4. ncbi request reprint Defining wild-type life span in Caenorhabditis elegans
    D Gems
    Department of Biology, University College London, England
    J Gerontol A Biol Sci Med Sci 55:B215-9. 2000
  5. pmc An integrated theory of ageing in the nematode Caenorhabditis elegans
    D Gems
    Department of Biology, University College London, UK
    J Anat 197:521-8. 2000
  6. ncbi request reprint Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    D J Clancy
    Department of Biology, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    Science 292:104-6. 2001
  7. ncbi request reprint Longevity and ageing in parasitic and free-living nematodes
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
    Biogerontology 1:289-307. 2000
  8. ncbi request reprint An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins
    D Gems
    Wellcome Research Centre for Parasitic Infections, Department of Biology, Imperial College of Science, Technology and Medicine, London, United Kingdom
    J Biol Chem 270:18517-22. 1995

Detail Information

Publications8

  1. ncbi request reprint Nematode ageing: Putting metabolic theories to the test
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, London, NW1 2HE, UK
    Curr Biol 9:R614-6. 1999
    ..New findings support the former, but not the latter interpretation...
  2. pmc Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    D Gems
    The Galton Laboratory, Department of Biology, University College London, England
    Genetics 154:1597-610. 2000
    ..This variability was reduced when dead bacteria were used as food. Maintenance on dead bacteria extended both male and hermaphrodite longevity...
  3. ncbi request reprint Insulin/IGF signalling and ageing: seeing the bigger picture
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, NW1 2HE, London, UK
    Curr Opin Genet Dev 11:287-92. 2001
    ..The focus now is on how this pathway is regulated, how it controls nematode ageing, and how this relates to the ageing process in higher animals...
  4. ncbi request reprint Defining wild-type life span in Caenorhabditis elegans
    D Gems
    Department of Biology, University College London, England
    J Gerontol A Biol Sci Med Sci 55:B215-9. 2000
    ..We infer that the longest-lived N2 variant best resembles the original N2 isolate. This is the N2 male stock currently distributed by the Caenorhabditis Genetics Center...
  5. pmc An integrated theory of ageing in the nematode Caenorhabditis elegans
    D Gems
    Department of Biology, University College London, UK
    J Anat 197:521-8. 2000
    ..This tripartite theory of ageing gives rise to a number of predictions that may be tested experimentally...
  6. ncbi request reprint Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    D J Clancy
    Department of Biology, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, UK
    Science 292:104-6. 2001
    ..The dwarf phenotype of chico homozygotes was also unnecessary for extension of life-span. The role of insulin/IGF signaling in regulating animal aging is therefore evolutionarily conserved...
  7. ncbi request reprint Longevity and ageing in parasitic and free-living nematodes
    D Gems
    Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK
    Biogerontology 1:289-307. 2000
    ..The possible evolutionary and mechanistic causes of such differences in ageing are discussed...
  8. ncbi request reprint An abundant, trans-spliced mRNA from Toxocara canis infective larvae encodes a 26-kDa protein with homology to phosphatidylethanolamine-binding proteins
    D Gems
    Wellcome Research Centre for Parasitic Infections, Department of Biology, Imperial College of Science, Technology and Medicine, London, United Kingdom
    J Biol Chem 270:18517-22. 1995
    ..Assays with the T. canis recombinant 26-kDa protein expressed as a fusion with maltose-binding protein have confirmed phosphatidylethanolamine-binding specificity for this novel product...