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Species | Derek GathererSummaryAffiliation: University of Glasgow Country: UK Publications
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Publications
So what do we really mean when we say that systems biology is holistic?Derek Gatherer
MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
BMC Syst Biol 4:22. 2010..The histories of holism and reductionism in the philosophy of biology are reviewed, and the current debate in systems biology is placed in context...
The 2009 H1N1 influenza outbreak in its historical contextDerek Gatherer
MRC Virology Unit, Institute of Virology, Glasgow, UK
J Clin Virol 45:174-8. 2009..Given that the divergence between H1 and its nearest serotype neighbour H2 is around 40-46%, the 2009 H1 may be broadly considered as halfway towards a new serotype. The current situation is one of antigenic pseudo-shift...
Passage in egg culture is a major cause of apparent positive selection in influenza B hemagglutininDerek Gatherer
MRC Virology Unit, University of Glasgow, Church Street, Glasgow, UK
J Med Virol 82:123-7. 2010..The major cause of molecular adaptation in influenza B hemagglutinin proteins may well be laboratory eggs rather than natural hosts...
The Little Ice Age and the emergence of influenza ADerek Gatherer
MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
Med Hypotheses 75:359-62. 2010....
Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimensCharles Cunningham
MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow G11 5JR, UK
J Gen Virol 91:605-15. 2010..These observations imply that HCMV mutants exist in human infections...
High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169Amanda J Bradley
MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK
J Gen Virol 90:2375-80. 2009..Like other AD169 variants, varUC is mutated in genes RL5A, RL13, UL36 and UL131A. A subpopulation of varUC contains an additional deletion affecting genes IRS1, US1 and US2...
Genotypic analysis of two hypervariable human cytomegalovirus genesAmanda J Bradley
MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow, United Kingdom
J Med Virol 80:1615-23. 2008..The emerging scenario is that the HCMV genotypes developed in early human populations (or even earlier), becoming established via founder or bottleneck effects, and have spread, recombined and mixed worldwide in more recent times...
