Derek Gatherer

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. pmc So what do we really mean when we say that systems biology is holistic?
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
    BMC Syst Biol 4:22. 2010
  2. ncbi The 2009 H1N1 influenza outbreak in its historical context
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, Glasgow, UK
    J Clin Virol 45:174-8. 2009
  3. pmc Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis
    Derek Gatherer
    MRC Virology Unit, Institute of Virology Church Street, Glasgow G11 5JR, UK
    Evol Bioinform Online 3:211-36. 2007
  4. pmc Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR UK
    Bioinform Biol Insights 1:101-26. 2009
  5. doi Passage in egg culture is a major cause of apparent positive selection in influenza B hemagglutinin
    Derek Gatherer
    MRC Virology Unit, University of Glasgow, Church Street, Glasgow, UK
    J Med Virol 82:123-7. 2010
  6. doi The Little Ice Age and the emergence of influenza A
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
    Med Hypotheses 75:359-62. 2010
  7. pmc Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens
    Charles Cunningham
    MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow G11 5JR, UK
    J Gen Virol 91:605-15. 2010
  8. pmc High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169
    Amanda J Bradley
    MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK
    J Gen Virol 90:2375-80. 2009
  9. pmc Genotypic analysis of two hypervariable human cytomegalovirus genes
    Amanda J Bradley
    MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow, United Kingdom
    J Med Virol 80:1615-23. 2008

Collaborators

Detail Information

Publications9

  1. pmc So what do we really mean when we say that systems biology is holistic?
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
    BMC Syst Biol 4:22. 2010
    ..The histories of holism and reductionism in the philosophy of biology are reviewed, and the current debate in systems biology is placed in context...
  2. ncbi The 2009 H1N1 influenza outbreak in its historical context
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, Glasgow, UK
    J Clin Virol 45:174-8. 2009
    ..Given that the divergence between H1 and its nearest serotype neighbour H2 is around 40-46%, the 2009 H1 may be broadly considered as halfway towards a new serotype. The current situation is one of antigenic pseudo-shift...
  3. pmc Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis
    Derek Gatherer
    MRC Virology Unit, Institute of Virology Church Street, Glasgow G11 5JR, UK
    Evol Bioinform Online 3:211-36. 2007
    ..These results may also be more generally applicable to the use of SOMs for other complex data sets, such as microarray data...
  4. pmc Peptide vocabulary analysis reveals ultra-conservation and homonymity in protein sequences
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR UK
    Bioinform Biol Insights 1:101-26. 2009
    ..Homonyms may be useful in detecting convergent evolution and positive selection in protein evolution. Ultra-conserved words may be useful in identifying structures intolerant to substitution over long periods of evolutionary time...
  5. doi Passage in egg culture is a major cause of apparent positive selection in influenza B hemagglutinin
    Derek Gatherer
    MRC Virology Unit, University of Glasgow, Church Street, Glasgow, UK
    J Med Virol 82:123-7. 2010
    ..The major cause of molecular adaptation in influenza B hemagglutinin proteins may well be laboratory eggs rather than natural hosts...
  6. doi The Little Ice Age and the emergence of influenza A
    Derek Gatherer
    MRC Virology Unit, Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, UK
    Med Hypotheses 75:359-62. 2010
    ....
  7. pmc Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens
    Charles Cunningham
    MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow G11 5JR, UK
    J Gen Virol 91:605-15. 2010
    ..These observations imply that HCMV mutants exist in human infections...
  8. pmc High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169
    Amanda J Bradley
    MRC Virology Unit, Institute of Virology, Church Street, Glasgow G11 5JR, UK
    J Gen Virol 90:2375-80. 2009
    ..Like other AD169 variants, varUC is mutated in genes RL5A, RL13, UL36 and UL131A. A subpopulation of varUC contains an additional deletion affecting genes IRS1, US1 and US2...
  9. pmc Genotypic analysis of two hypervariable human cytomegalovirus genes
    Amanda J Bradley
    MRC Virology Unit, Institute of Virology, University of Glasgow, Glasgow, United Kingdom
    J Med Virol 80:1615-23. 2008
    ..The emerging scenario is that the HCMV genotypes developed in early human populations (or even earlier), becoming established via founder or bottleneck effects, and have spread, recombined and mixed worldwide in more recent times...