Stephen F Garner

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Glycoprotein V: the predominant target antigen in gold-induced autoimmune thrombocytopenia
    Stephen F Garner
    Division of Transfusion Medicine, University of Cambridge and National Blood Service East Anglia Centre, United Kingdom
    Blood 100:344-6. 2002
  2. ncbi request reprint Teicoplanin-dependent antibodies: detection and characterization
    Stephen F Garner
    National Blood Service, Cambridge, UK
    Br J Haematol 129:279-81. 2005
  3. pmc Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins
    Marie N O'Connor
    Department of Haematology, University of Cambridge, Cambridge, United Kingdom
    Blood 113:4754-62. 2009
  4. doi request reprint Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation
    Adam Walker
    Domantis Ltd, 315 Cambridge Science Park, Cambridge, UK
    Platelets 20:268-76. 2009
  5. pmc A HaemAtlas: characterizing gene expression in differentiated human blood cells
    Nicholas A Watkins
    Department of Haematology, University of Cambridge, National Health Service Blood and Transplant, Cambridge, United Kingdom
    Blood 113:e1-9. 2009
  6. pmc A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function
    Nicole Soranzo
    Human Genetics Department, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
    Blood 113:3831-7. 2009
  7. ncbi request reprint Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
    Peter A Smethurst
    Department of Haematology, University of Cambridge and National Blood Service Cambridge, Long Road, Cambridge, CB2 2PT, United Kingdom
    Blood 103:903-11. 2004
  8. ncbi request reprint A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia
    Cedric Ghevaert
    Department of Haematology, University of Cambridge, UK
    Blood 111:3407-14. 2008
  9. doi request reprint A single-nucleotide polymorphism in the human ITGB3 gene is associated with the platelet-specific alloantigen Va (HPA-17bw) involved in fetal maternal alloimmune thrombocytopenia
    Prachi Stafford
    The Department of Haematology, University of Cambridge and NHS Blood and Transplant, Cambridge, UK
    Transfusion 48:1432-8. 2008
  10. doi request reprint Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality
    Stephen F Garner
    Department of Haematology, University of Cambridge, Cambridge, UK
    Transfusion 48:673-80. 2008

Detail Information

Publications12

  1. ncbi request reprint Glycoprotein V: the predominant target antigen in gold-induced autoimmune thrombocytopenia
    Stephen F Garner
    Division of Transfusion Medicine, University of Cambridge and National Blood Service East Anglia Centre, United Kingdom
    Blood 100:344-6. 2002
    ..Autoantibodies recognizing GPV were not seen in the 28 nonthrombocytopenic control RA patients. Thus, GPV seems to be targeted in gold-induced autoimmune thrombocytopenia...
  2. ncbi request reprint Teicoplanin-dependent antibodies: detection and characterization
    Stephen F Garner
    National Blood Service, Cambridge, UK
    Br J Haematol 129:279-81. 2005
    ....
  3. pmc Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins
    Marie N O'Connor
    Department of Haematology, University of Cambridge, Cambridge, United Kingdom
    Blood 113:4754-62. 2009
    ..We conclude that phenotypic analysis of MO-injected zebrafish is a fast and powerful method for initial screening of novel platelet proteins for function in thrombosis...
  4. doi request reprint Single domain antibodies against the collagen signalling receptor glycoprotein VI are inhibitors of collagen induced thrombus formation
    Adam Walker
    Domantis Ltd, 315 Cambridge Science Park, Cambridge, UK
    Platelets 20:268-76. 2009
    ..These data, together with the desirable properties of Domain Antibodies, show that dAbs could potentially be used to generate novel biopharmaceuticals with anti-thrombotic properties...
  5. pmc A HaemAtlas: characterizing gene expression in differentiated human blood cells
    Nicholas A Watkins
    Department of Haematology, University of Cambridge, National Health Service Blood and Transplant, Cambridge, United Kingdom
    Blood 113:e1-9. 2009
    ..The data, which are freely accessible, will be invaluable for future studies on hematopoiesis and the role of specific genes and will also aid the understanding of the recent genome-wide association studies...
  6. pmc A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function
    Nicole Soranzo
    Human Genetics Department, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom
    Blood 113:3831-7. 2009
    ....
  7. ncbi request reprint Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
    Peter A Smethurst
    Department of Haematology, University of Cambridge and National Blood Service Cambridge, Long Road, Cambridge, CB2 2PT, United Kingdom
    Blood 103:903-11. 2004
    ..Antibody 10B12 showed significantly reduced binding to the hD1D2-E59, and, on that basis, the GPVI:10B12 interface was modeled...
  8. ncbi request reprint A nonsynonymous SNP in the ITGB3 gene disrupts the conserved membrane-proximal cytoplasmic salt bridge in the alphaIIbbeta3 integrin and cosegregates dominantly with abnormal proplatelet formation and macrothrombocytopenia
    Cedric Ghevaert
    Department of Haematology, University of Cambridge, UK
    Blood 111:3407-14. 2008
    ..We conclude that the constitutive activation of the alphaIIbbeta3-H723 receptor causes abnormal proplatelet formation, leading to incorrect sizing of platelets and the thrombocytopenia observed in the pedigree...
  9. doi request reprint A single-nucleotide polymorphism in the human ITGB3 gene is associated with the platelet-specific alloantigen Va (HPA-17bw) involved in fetal maternal alloimmune thrombocytopenia
    Prachi Stafford
    The Department of Haematology, University of Cambridge and NHS Blood and Transplant, Cambridge, UK
    Transfusion 48:1432-8. 2008
    ..This PLT antigen was localized to the integrin alphaIIbbeta3 (GPIIbIIIa) but its genetic basis was not defined...
  10. doi request reprint Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality
    Stephen F Garner
    Department of Haematology, University of Cambridge, Cambridge, UK
    Transfusion 48:673-80. 2008
    ....
  11. ncbi request reprint Expression of a single-chain human leukocyte antigen-DRA/DRB3*01:01 molecule and differential binding of a monoclonal antibody in the presence of specifically bound human platelet antigen-1a peptide
    Evelien E Bouwmans
    Department of Haematology, University of Cambridge, Cambridge, UK
    Transfusion 54:1478-85. 2014
    ..An antibody reagent that has a different binding affinity to HLA-DRA/DRB3*01:01 with and without the β3 -L33 peptide would be a valuable reagent to study peptide presentation on maternal antigen-presenting cells...
  12. ncbi request reprint Production of calmodulin-tagged proteins in Drosophila Schneider S2 cells: a novel system for antigen production and phage antibody isolation
    Nicola S Jennings
    Department of Haematology, University of Cambridge and the National Blood Service Cambridge, Cambridge, UK
    J Immunol Methods 316:75-83. 2006
    ....