C Gardiner

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Self-monitoring of oral anticoagulation: does it work outside trial conditions?
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    J Clin Pathol 62:168-71. 2009
  2. ncbi request reprint A randomised control trial of patient self-management of oral anticoagulation compared with patient self-testing
    Chris Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Br J Haematol 132:598-603. 2006
  3. ncbi request reprint Recommendations for evaluation of coagulation analyzers
    Chris Gardiner
    University College London Hospitals, London, UK
    Lab Hematol 12:32-8. 2006
  4. ncbi request reprint Can oral anticoagulation be managed using telemedicine and patient self-testing? A pilot study
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Clin Lab Haematol 28:122-5. 2006
  5. doi request reprint Measuring thrombin generation based sensitivity to activated protein C using an automated coagulometer (ACL 9000)
    C Gardiner
    Department of Haematology, University College London, London, UK
    Int J Lab Hematol 30:261-8. 2008
  6. doi request reprint The clinical significance of differences between point-of-care and laboratory INR methods in over-anticoagulated patients
    A S Lawrie
    Haemostasis Research Unit, Department of Haematology, University College London, London, UK
    Thromb Res 130:110-4. 2012
  7. ncbi request reprint The importance of locally derived reference ranges and standardized calculation of dilute Russell's viper venom time results in screening for lupus anticoagulant
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Br J Haematol 111:1230-5. 2000
  8. doi request reprint Diagnosis of antiphospholipid syndrome in routine clinical practice
    C Gardiner
    Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK
    Lupus 22:18-25. 2013
  9. ncbi request reprint An evaluation of screening tests for defects in the protein C pathway: commercial kits lack sensitivity and specificity
    C Gardiner
    Department of Haematology, University College London Hospital, London, UK
    Blood Coagul Fibrinolysis 13:155-63. 2002
  10. ncbi request reprint Individual patient meta-analysis of self-monitoring of an oral anticoagulation protocol
    Rafael Perera
    Department of Primary Health Care, University of Oxford, UK
    J Heart Valve Dis 17:233-8. 2008

Collaborators

Detail Information

Publications14

  1. pmc Self-monitoring of oral anticoagulation: does it work outside trial conditions?
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    J Clin Pathol 62:168-71. 2009
    ..Patient self-monitoring (PSM) of oral anticoagulation therapy (OAT) can improve anticoagulant control, but poor uptake and high dropout rates have prompted suggestions that PSM is suitable for only a minority of patients in the UK...
  2. ncbi request reprint A randomised control trial of patient self-management of oral anticoagulation compared with patient self-testing
    Chris Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Br J Haematol 132:598-603. 2006
    ..86) also showed a significant difference. The quality of warfarin control in both PST and PSM may be superior to that achieved by conventional management in a specialised hospital anticoagulation clinic...
  3. ncbi request reprint Recommendations for evaluation of coagulation analyzers
    Chris Gardiner
    University College London Hospitals, London, UK
    Lab Hematol 12:32-8. 2006
  4. ncbi request reprint Can oral anticoagulation be managed using telemedicine and patient self-testing? A pilot study
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Clin Lab Haematol 28:122-5. 2006
    ..In conclusion, this pilot study showed that telemedicine is a feasible option for anticoagulant management, but that the technology requires thorough testing prior to installation...
  5. doi request reprint Measuring thrombin generation based sensitivity to activated protein C using an automated coagulometer (ACL 9000)
    C Gardiner
    Department of Haematology, University College London, London, UK
    Int J Lab Hematol 30:261-8. 2008
    ..73-1.06; ETP(+APC) 0.42-1.07. ETP(+APC) was found to be sensitive to factor V Leiden, oral contraceptive use, low levels of protein S and tissue factor pathway inhibitor and increased plasma factor VIII...
  6. doi request reprint The clinical significance of differences between point-of-care and laboratory INR methods in over-anticoagulated patients
    A S Lawrie
    Haemostasis Research Unit, Department of Haematology, University College London, London, UK
    Thromb Res 130:110-4. 2012
    ..5; the relationships between the INR and levels of vitamin K-dependent coagulation factors (VKD-CF) and thrombin generation test (TGT) parameters; and the impact that variation in results would have on warfarin dosing...
  7. ncbi request reprint The importance of locally derived reference ranges and standardized calculation of dilute Russell's viper venom time results in screening for lupus anticoagulant
    C Gardiner
    Department of Haematology, University College London Hospitals, London, UK
    Br J Haematol 111:1230-5. 2000
    ..Standardizing DRVVT interpretation in this way should improve the consistency of LA detection...
  8. doi request reprint Diagnosis of antiphospholipid syndrome in routine clinical practice
    C Gardiner
    Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK
    Lupus 22:18-25. 2013
    ..5% and 29.4% of patients, respectively. Our data suggest that LA, aCL and aβ(2)GPI testing are all required for the accurate diagnosis of APS and that low-titre antibodies should be included in the diagnosis of obstetric APS...
  9. ncbi request reprint An evaluation of screening tests for defects in the protein C pathway: commercial kits lack sensitivity and specificity
    C Gardiner
    Department of Haematology, University College London Hospital, London, UK
    Blood Coagul Fibrinolysis 13:155-63. 2002
    ..We conclude that all four kits lack the sensitivity and specificity required for routine laboratory screening for defects in the protein C pathway and cannot replace assays for the individual proteins of this system...
  10. ncbi request reprint Individual patient meta-analysis of self-monitoring of an oral anticoagulation protocol
    Rafael Perera
    Department of Primary Health Care, University of Oxford, UK
    J Heart Valve Dis 17:233-8. 2008
    ..In order to overcome these limitations and allow further investigation of the data, the study aim is to undertake an Individual Patient Data (IPD) meta-analysis...
  11. ncbi request reprint Detection of acquired resistance to activated protein C associated with antiphospholipid antibodies using a novel clotting assay
    Chris Gardiner
    Department of Haematology, University College London, UK
    Blood Coagul Fibrinolysis 17:477-83. 2006
    ..Purified aPA IgG caused a dose-dependent increase in APC resistance when added to normal plasma. We conclude that aPA-associated acquired APC resistance is a common feature of APS and may be independent of anti-beta2GPI...
  12. ncbi request reprint Patient self-testing is a reliable and acceptable alternative to laboratory INR monitoring
    Chris Gardiner
    Department of Haematology, University College London Hospitals NHS Trust, London, UK
    Br J Haematol 128:242-7. 2005
    ..We conclude that PST is a reliable alternative to hospital clinic attendance and is acceptable to the majority of suitably trained patients...
  13. doi request reprint Performance evaluation of a new small-volume coagulation monitor: the SmartCheck INR system
    Chris Gardiner
    Department of Haematology, University College London Hospitals, London, England
    Am J Clin Pathol 129:500-4. 2008
    ..7%. The SmartCheck INR provides accurate and reproducible results and is suitable for routine monitoring of oral anticoagulant therapy in the majority of patients...
  14. ncbi request reprint The SmartCheck INR system
    Chris Gardiner
    Am J Clin Pathol 129:826. 2008