Earn H Gan

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. doi A UK epidemic of testosterone prescribing, 2001-2010
    Earn H Gan
    Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 79:564-70. 2013
  2. pmc The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease
    Earn H Gan
    Institute of Genetic Medicine, International Centre for Life, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK
    Eur J Endocrinol 167:825-8. 2012
  3. pmc Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people
    Earn H Gan
    Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, United Kingdom
    J Clin Endocrinol Metab 97:3438-49. 2012
  4. doi The role of a nonsynonymous CD226 (DNAX-accessory molecule-1) variant (Gly 307Ser) in isolated Addison's disease and autoimmune polyendocrinopathy type 2 pathogenesis
    Earn H Gan
    Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 75:165-8. 2011
  5. doi Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment
    Earn H Gan
    Institute of Genetic Medicine E H G, K M, A L M, P P, R Q, S H S P, Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom the Endocrine Unit E H G, A L M, P P, S G B, R A J, R Q, S H S P, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom the Centre for Endocrinology, Diabetes, and Metabolism B A H, W A, University of Birmingham, Birmingham B15 2TT, United Kingdom and RSR Ltd S C, J F, FIRS Laboratories, Cardiff CF4 5DU, United Kingdom
    J Clin Endocrinol Metab 99:111-8. 2014
  6. doi The effect of B cell depletion therapy on anti-TSH receptor antibodies and clinical outcome in glucocorticoid-refractory Graves' orbitopathy
    Anna L Mitchell
    Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 79:437-42. 2013
  7. doi Association of Autoimmune Addison's Disease with Alleles of STAT4 and GATA3 in European Cohorts
    Anna L Mitchell
    Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom
    PLoS ONE 9:e88991. 2014

Detail Information

Publications7

  1. doi A UK epidemic of testosterone prescribing, 2001-2010
    Earn H Gan
    Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 79:564-70. 2013
    ..Therefore, we aimed to examine trends in testosterone prescribing in UK primary care over the last 10 years...
  2. pmc The role of functionally defective rare germline variants of sialic acid acetylesterase in autoimmune Addison's disease
    Earn H Gan
    Institute of Genetic Medicine, International Centre for Life, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK
    Eur J Endocrinol 167:825-8. 2012
    ..We performed a case-control study to determine whether these rare variants are associated with a rarer condition, AAD...
  3. pmc Clinical review: The thyroid in mind: cognitive function and low thyrotropin in older people
    Earn H Gan
    Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, United Kingdom
    J Clin Endocrinol Metab 97:3438-49. 2012
    ..We performed a detailed systematic review to assess the evidence available to support the association between these two conditions...
  4. doi The role of a nonsynonymous CD226 (DNAX-accessory molecule-1) variant (Gly 307Ser) in isolated Addison's disease and autoimmune polyendocrinopathy type 2 pathogenesis
    Earn H Gan
    Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 75:165-8. 2011
    ..PATIENT AND DESIGN: We genotyped rs763361 in a UK cohort of 326 AAD subjects [183 with associated autoimmune conditions - autoimmune polyendocrinopathy syndrome type-2 (APS2)] and 311 healthy controls, using a Taqman genotyping assay...
  5. doi Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment
    Earn H Gan
    Institute of Genetic Medicine E H G, K M, A L M, P P, R Q, S H S P, Newcastle University, Newcastle upon Tyne NE1 3BZ, United Kingdom the Endocrine Unit E H G, A L M, P P, S G B, R A J, R Q, S H S P, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, United Kingdom the Centre for Endocrinology, Diabetes, and Metabolism B A H, W A, University of Birmingham, Birmingham B15 2TT, United Kingdom and RSR Ltd S C, J F, FIRS Laboratories, Cardiff CF4 5DU, United Kingdom
    J Clin Endocrinol Metab 99:111-8. 2014
    ..In health, adrenocortical cells undergo continuous self-renewal from a population of subcapsular progenitor cells, under the influence of ACTH, suggesting a therapeutic possibility...
  6. doi The effect of B cell depletion therapy on anti-TSH receptor antibodies and clinical outcome in glucocorticoid-refractory Graves' orbitopathy
    Anna L Mitchell
    Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne, UK
    Clin Endocrinol (Oxf) 79:437-42. 2013
    ..This case series documents the response of nine individuals with glucocorticoid-refractory Graves' orbitopathy (GO) to B cell depletion therapy with rituximab (RTX)...
  7. doi Association of Autoimmune Addison's Disease with Alleles of STAT4 and GATA3 in European Cohorts
    Anna L Mitchell
    Institute of Genetic Medicine, Newcastle University, Newcastle, United Kingdom
    PLoS ONE 9:e88991. 2014
    ..The majority of the genetic component to disease susceptibility has yet to be accounted for...